tenidap (CHEBI:35847)

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ChEBI Name	tenidap

ChEBI ID	CHEBI:35847

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C14H9ClN2O3S

Net Charge

Average Mass

320.75164

Monoisotopic Mass

320.00224

InChI

InChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,18H,(H2,16,20)/b12-11-

InChIKey

LXIKEPCNDFVJKC-QXMHVHEDSA-N

SMILES

NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12

Roles Classification
Biological Role(s):	EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.

Application(s):	non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.

ChEBI Ontology
Outgoing	tenidap (CHEBI:35847) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) tenidap (CHEBI:35847) has role non-steroidal anti-inflammatory drug (CHEBI:35475) tenidap (CHEBI:35847) is a indoles (CHEBI:24828) tenidap (CHEBI:35847) is a organochlorine compound (CHEBI:36683) tenidap (CHEBI:35847) is a thiophenes (CHEBI:26961) tenidap (CHEBI:35847) is a ureas (CHEBI:47857)

IUPAC Name

(3Z)-5-chloro-3-[hydroxy(2-thienyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-1-carboxamide

Synonyms	Sources
(Z)-5-Chloro-3-(alpha-hydroxy-2-thenylidene)-2-oxo-1-indolinecarboxamide	ChemIDplus
Tenidap	ChemIDplus

Registry Number	Type	Source
120210-48-2	CAS Registry Number	ChemIDplus

Last Modified

22 February 2017