CHEBI:66577 - lindechunine A

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ChEBI Name lindechunine A
ChEBI ID CHEBI:66577
Definition An isoquinoline alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2, methoxy groups at positions 3 and 11 and a hydroxy group at position 10. Isolated from the roots of Lindera chunii, it exhibits anti-HIV activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H13NO6
Net Charge 0
Average Mass 351.30960
Monoisotopic Mass 351.07429
InChI InChI=1S/C19H13NO6/c1-23-16-9-5-6-20-14-11(9)13(18-19(16)26-7-25-18)12-8(15(14)22)3-4-10(21)17(12)24-2/h3-6,21H,7H2,1-2H3
InChIKey ZLFKJSKABHQLAQ-UHFFFAOYSA-N
SMILES COc1c(O)ccc2C(=O)c3nccc4c(OC)c5OCOc5c(-c12)c34
Metabolite of Species Details
Lindera chunii (NCBI:txid344093) Found in root (BTO:0001188). See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
HIV-1 integrase inhibitor
An inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing lindechunine A (CHEBI:66577) has functional parent aporphine (CHEBI:35643)
lindechunine A (CHEBI:66577) has role HIV-1 integrase inhibitor (CHEBI:67268)
lindechunine A (CHEBI:66577) has role metabolite (CHEBI:25212)
lindechunine A (CHEBI:66577) is a aromatic ether (CHEBI:35618)
lindechunine A (CHEBI:66577) is a cyclic ketone (CHEBI:3992)
lindechunine A (CHEBI:66577) is a isoquinoline alkaloid (CHEBI:24921)
lindechunine A (CHEBI:66577) is a organic heteropentacyclic compound (CHEBI:38164)
lindechunine A (CHEBI:66577) is a oxacycle (CHEBI:38104)
lindechunine A (CHEBI:66577) is a phenols (CHEBI:33853)
IUPAC Name
11-hydroxy-4,12-dimethoxy-8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-8-one
Registry Number Type Source
9292933 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
12237535 PubMed citation Europe PMC
Last Modified
22 March 2013