CHEBI:84638 - 8-(4-chlorophenylthio)-cGMP

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ChEBI Name 8-(4-chlorophenylthio)-cGMP
ChEBI ID CHEBI:84638
Definition A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP in which the hydrogen at position 2 on the purine fragment is replaced by a 4-chlorophenylthio group.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Margaret Duesbury
Supplier Information
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Formula C16H15ClN5O7PS
Net Charge 0
Average Mass 487.81100
Monoisotopic Mass 487.01183
InChI InChI=1S/C16H15ClN5O7PS/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(28-14)5-27-30(25,26)29-11/h1-4,8,10-11,14,23H,5H2,(H,25,26)(H3,18,20,21,24)/t8-,10-,11-,14-/m1/s1
InChIKey ZDJHIEHUVPCEDK-IDTAVKCVSA-N
SMILES Nc1nc2n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c(Sc3ccc(Cl)cc3)nc2c(=O)[nH]1
Roles Classification
Biological Role(s): protein kinase agonist
An agonist that selectively binds to and activates a protein kinase receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 8-(4-chlorophenylthio)-cGMP (CHEBI:84638) has functional parent 3',5'-cyclic GMP (CHEBI:16356)
8-(4-chlorophenylthio)-cGMP (CHEBI:84638) has role protein kinase agonist (CHEBI:64106)
8-(4-chlorophenylthio)-cGMP (CHEBI:84638) is a 3',5'-cyclic purine nucleotide (CHEBI:19834)
8-(4-chlorophenylthio)-cGMP (CHEBI:84638) is a aryl sulfide (CHEBI:35683)
8-(4-chlorophenylthio)-cGMP (CHEBI:84638) is a organochlorine compound (CHEBI:36683)
8-(4-chlorophenylthio)-cGMP (CHEBI:84638) is a ribonucleotide (CHEBI:26561)
8-(4-chlorophenylthio)-cGMP (CHEBI:84638) is conjugate acid of 8-(4-chlorophenylthio)-cGMP(1−) (CHEBI:91239)
Incoming 8-(4-chlorophenylthio)-cGMP(1−) (CHEBI:91239) is conjugate base of 8-(4-chlorophenylthio)-cGMP (CHEBI:84638)
IUPAC Name
2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2λ5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one
Synonyms Sources
8-((4-Chlorophenyl)thio)cyclic-3',5'-GMP ChemIDplus
8-(4-chlorophenylthio)-3',5'-cyclic GMP ChEBI
8-(4-chlorophenylthio)-cyclic GMP ChEBI
8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphate ChEBI
8-(4-chlorophenylthio)guanosine 3',5'-cyclic phosphate ChEBI
8-pCPT-cGMP ChEBI
Registry Numbers Types Sources
1199328 Reaxys Registry Number Reaxys
54364-02-2 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
24481877 PubMed citation Europe PMC
24534906 PubMed citation Europe PMC
24605759 PubMed citation SUBMITTER
Last Modified
17 February 2016