CHEBI:59167 - bambuterol hydrochloride

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ChEBI Name bambuterol hydrochloride
ChEBI ID CHEBI:59167
Definition The hydrochloride salt of bambuterol. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C18H30ClN3O5
Net Charge 0
Average Mass 403.90100
Monoisotopic Mass 403.18740
InChI InChI=1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H
InChIKey LBARATORRVNNQM-UHFFFAOYSA-N
SMILES Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
EC 3.1.1.7 (acetylcholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
Application(s): sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
anti-asthmatic drug
A drug used to treat asthma.
bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing bambuterol hydrochloride (CHEBI:59167) has part bambuterol (CHEBI:553827)
bambuterol hydrochloride (CHEBI:59167) has role β-adrenergic agonist (CHEBI:35522)
bambuterol hydrochloride (CHEBI:59167) has role anti-asthmatic drug (CHEBI:49167)
bambuterol hydrochloride (CHEBI:59167) has role bronchodilator agent (CHEBI:35523)
bambuterol hydrochloride (CHEBI:59167) has role EC 3.1.1.7 (acetylcholinesterase) inhibitor (CHEBI:38462)
bambuterol hydrochloride (CHEBI:59167) has role prodrug (CHEBI:50266)
bambuterol hydrochloride (CHEBI:59167) has role sympathomimetic agent (CHEBI:35524)
bambuterol hydrochloride (CHEBI:59167) is a carbamate ester (CHEBI:23003)
bambuterol hydrochloride (CHEBI:59167) is a hydrochloride (CHEBI:36807)
bambuterol hydrochloride (CHEBI:59167) is a phenylethanolamines (CHEBI:25990)
Incoming (R)-bambuterol hydrochloride (CHEBI:59182) is a bambuterol hydrochloride (CHEBI:59167)
(S)-bambuterol hydrochloride (CHEBI:59183) is a bambuterol hydrochloride (CHEBI:59167)
IUPAC Name
5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate) hydrochloride
Synonym Source
bambuterol HCl ChemIDplus
Manual Xrefs Databases
D07489 KEGG DRUG
DB01408 DrugBank
US6075048 Patent
View more database links
Registry Numbers Types Sources
81732-46-9 CAS Registry Number ChemIDplus
81732-46-9 CAS Registry Number KEGG DRUG
9451479 Beilstein Registry Number Beilstein
Last Modified
19 April 2010