CHEBI:65606 - celebixanthone

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ChEBI Name celebixanthone
ChEBI ID CHEBI:65606
Definition A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 3, 4 and 8, a methoxy group at position 2 and a prenyl group at position 1. Isolated from Cratoxylum celebicum and the roots of Cratoxylum cochinchinense, it exhibits cytotoxic and antimalarial activities.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H18O6
Net Charge 0
Average Mass 342.34260
Monoisotopic Mass 342.11034
InChI InChI=1S/C19H18O6/c1-9(2)7-8-10-13-15(21)14-11(20)5-4-6-12(14)25-19(13)17(23)16(22)18(10)24-3/h4-7,20,22-23H,8H2,1-3H3
InChIKey OQPZXQVAOOHEFP-UHFFFAOYSA-N
SMILES COc1c(O)c(O)c2oc3cccc(O)c3c(=O)c2c1CC=C(C)C
Metabolite of Species Details
Cratoxylum celebicum (IPNI:433052-1) See: DOI
Cratoxylum cochinchinense (NCBI:txid271749) Found in root (BTO:0001188). See: PubMed
Roles Classification
Biological Role(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing celebixanthone (CHEBI:65606) has role antimalarial (CHEBI:38068)
celebixanthone (CHEBI:65606) has role antineoplastic agent (CHEBI:35610)
celebixanthone (CHEBI:65606) has role metabolite (CHEBI:25212)
celebixanthone (CHEBI:65606) is a aromatic ether (CHEBI:35618)
celebixanthone (CHEBI:65606) is a polyphenol (CHEBI:26195)
celebixanthone (CHEBI:65606) is a xanthones (CHEBI:51149)
Incoming 5-O-methylcelebixanthone (CHEBI:65607) has functional parent celebixanthone (CHEBI:65606)
IUPAC Name
3,4,8-trihydroxy-2-methoxy-1-(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
Registry Number Type Source
1298314 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
16651783 PubMed citation Europe PMC
Last Modified
10 December 2012