CHEBI:132869 - cyclomulberrin

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ChEBI Name cyclomulberrin
ChEBI ID CHEBI:132869
Definition A extended flavonoid that is 6H,7H-chromeno[4,3-b]chromen-7-one which is substituted by a 2-methylprop-1-en-1-yl group at position 6, a 3-methylbut-2-en-1-yl group at position 11, and hydroxy groups at positions 3, 8, and 10. It is found in the bark of Morus species and has been reported to protect human neuronal cells derived from the human neuroblastoma SH-SY5Y cell line.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter qingping liu
Supplier Information
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Formula C25H24O6
Net Charge 0
Average Mass 420.455
Monoisotopic Mass 420.15729
InChI InChI=1S/C25H24O6/c1-12(2)5-7-15-17(27)11-18(28)21-23(29)22-20(9-13(3)4)30-19-10-14(26)6-8-16(19)25(22)31-24(15)21/h5-6,8-11,20,26-28H,7H2,1-4H3
InChIKey SYFDWXWLRGHYAJ-UHFFFAOYSA-N
SMILES CC(C)=CCC=1C(=CC(=C2C(C=3C(C=C(C)C)OC=4C=C(C=CC4C3OC12)O)=O)O)O
Metabolite of Species Details
Morus alba var. atropurpurea (NCBI:txid1453101) Found in twig (BTO:0001411). See: PubMed
Morus (NCBI:txid3497) From root bark See: PubMed
Morus alba (NCBI:txid3498) See: PubMed
Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): protective agent
Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cyclomulberrin (CHEBI:132869) has role plant metabolite (CHEBI:76924)
cyclomulberrin (CHEBI:132869) has role protective agent (CHEBI:50267)
cyclomulberrin (CHEBI:132869) is a chromenochromene (CHEBI:133135)
cyclomulberrin (CHEBI:132869) is a cyclic ketone (CHEBI:3992)
cyclomulberrin (CHEBI:132869) is a extended flavonoid (CHEBI:71037)
cyclomulberrin (CHEBI:132869) is a organic heterotetracyclic compound (CHEBI:38163)
cyclomulberrin (CHEBI:132869) is a polyphenol (CHEBI:26195)
Incoming cyclomorusin A (CHEBI:132868) has functional parent cyclomulberrin (CHEBI:132869)
IUPAC Name
3,8,10-trihydroxy-11-(3-methylbut-2-en-1-yl)-6-(2-methylprop-1-en-1-yl)-6H,7H-chromeno[4,3-b]chromen-7-one
Manual Xrefs Databases
C00004061 KNApSAcK
HMDB0030688 HMDB
View more database links
Registry Numbers Types Sources
1631347 Reaxys Registry Number Reaxys
19275-51-5 CAS Registry Number HMDB
Citations Waiting for Citations Types Sources
19149258 PubMed citation Europe PMC
20815207 PubMed citation Europe PMC
22297755 PubMed citation Europe PMC
7903365 PubMed citation Europe PMC
8435100 PubMed citation Europe PMC
Last Modified
25 August 2016