CHEBI:81471 - 7α-hydroxydehydroepiandrosterone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 7α-hydroxydehydroepiandrosterone
ChEBI ID CHEBI:81471
ChEBI ASCII Name 7alpha-hydroxydehydroepiandrosterone
Definition An androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7α-position.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C19H28O3
Net Charge 0
Average Mass 304.425
Monoisotopic Mass 304.20384
InChI InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h10,12-15,17,20-21H,3-9H2,1-2H3/t12-,13-,14-,15+,17-,18-,19-/m0/s1
InChIKey OLPSAOWBSPXZEA-JIEICEMKSA-N
SMILES [C@@H]1([C@@]2([C@@]([C@@]3(C(C[C@@H](O)CC3)=C1)C)(CC[C@]4([C@]2(CCC4=O)[H])C)[H])[H])O
Metabolite of Species Details
Rattus norvegicus (NCBI:txid10116) See: PubMed
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role(s): estrogen
A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
rat metabolite
Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus).
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 7α-hydroxydehydroepiandrosterone (CHEBI:81471) has functional parent dehydroepiandrosterone (CHEBI:28689)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) has role anti-inflammatory agent (CHEBI:67079)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) has role antioxidant (CHEBI:22586)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) has role estrogen (CHEBI:50114)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) has role human xenobiotic metabolite (CHEBI:76967)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) has role rat metabolite (CHEBI:86264)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) is a 17-oxo steroid (CHEBI:19168)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) is a 3β-hydroxy-Δ5-steroid (CHEBI:1722)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) is a 7α-hydroxy steroid (CHEBI:36843)
7α-hydroxydehydroepiandrosterone (CHEBI:81471) is a androstanoid (CHEBI:50402)
IUPAC Name
3β,7α-dihydroxyandrost-5-en-17-one
Synonyms Sources
(3β,7α)-3,7-dihydroxyandrost-5-en-17-one IUPAC
3beta,7alpha-Dihydroxy-5-androstene-17-one KEGG COMPOUND
3β,7α-dihydroxyandrost-5-en-17-one UniProt
7alpha-Hydroxy-DHEA ChemIDplus
7alpha-Hydroxydehydroepiandrosterone ChemIDplus
7alpha-OH-DHEA KEGG COMPOUND
Manual Xrefs Databases
7alpha-Hydroxy-DHEA Wikipedia
C18045 KEGG COMPOUND
HMDB0004611 HMDB
LMST02020101 LIPID MAPS
US2003216588 Patent
View more database links
Registry Numbers Types Sources
2625222 Reaxys Registry Number Reaxys
53-00-9 CAS Registry Number KEGG COMPOUND
53-00-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12676372 PubMed citation Europe PMC
14977864 PubMed citation Europe PMC
15013692 PubMed citation Europe PMC
15476247 PubMed citation Europe PMC
15582537 PubMed citation Europe PMC
15698552 PubMed citation Europe PMC
15751070 PubMed citation Europe PMC
15784286 PubMed citation Europe PMC
16371229 PubMed citation Europe PMC
16524719 PubMed citation Europe PMC
16603347 PubMed citation Europe PMC
16713254 PubMed citation Europe PMC
16855167 PubMed citation Europe PMC
17152345 PubMed citation Europe PMC
17467270 PubMed citation Europe PMC
17681749 PubMed citation Europe PMC
18555503 PubMed citation Europe PMC
20024891 PubMed citation Europe PMC
20153344 PubMed citation Europe PMC
20553962 PubMed citation Europe PMC
24182335 PubMed citation Europe PMC
26680473 PubMed citation Europe PMC
26680484 PubMed citation Europe PMC
28948822 PubMed citation Europe PMC
Last Modified
10 April 2018