lidocaine hydrochloride (CHEBI:50512)

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ChEBI Name	lidocaine hydrochloride

ChEBI ID	CHEBI:50512

Definition	The anhydrous form of the hydrochloride salt of lidocaine.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formulae

C14H22N2O.HCl
C14H23ClN2O

Net Charge

Average Mass

270.79800

Monoisotopic Mass

270.14989

InChI

InChI=1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H

InChIKey

IYBQHJMYDGVZRY-UHFFFAOYSA-N

SMILES

[Cl-].CC[NH+](CC)CC(=O)Nc1c(C)cccc1C

Roles Classification
Application(s):	local anaesthetic Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.

ChEBI Ontology
Outgoing	lidocaine hydrochloride (CHEBI:50512) has part lidocaine (CHEBI:6456) lidocaine hydrochloride (CHEBI:50512) has role anti-arrhythmia drug (CHEBI:38070) lidocaine hydrochloride (CHEBI:50512) has role local anaesthetic (CHEBI:36333) lidocaine hydrochloride (CHEBI:50512) is a hydrochloride (CHEBI:36807)

Incoming	lidocaine hydrochloride monohydrate (CHEBI:60791) has part lidocaine hydrochloride (CHEBI:50512)

IUPAC Name

N-(2,6-dimethylphenyl)-N²,N²-diethylglycinamide hydrochloride

Synonyms	Sources
2-Diethylamino-2',6'-acetoxylidide hydrochloride	ChemIDplus
alpha-Diethylamino-2,6-acetoxylidine hydrochloride	ChemIDplus
Lidocaine hydrochloride anhydrous	ChemIDplus
omega-Diethylamino-2,6-dimethylacetanilide hydrochloride	ChemIDplus

Last Modified

09 December 2010

General Comment
2010-12-08	Both the anhydrous and the monohydrate forms of lidocaine hydrochloride are used as local anaesthetics, as well as for treatment of ventricular arrhythmias, especially after myocardial infarction.