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> Main
CHEBI:16810 - 2-oxoglutarate(2−)
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ChEBI Name
2-oxoglutarate(2−)
ChEBI ID
CHEBI:16810
ChEBI ASCII Name
2-oxoglutarate(2-)
Definition
An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid.
Stars
This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs
CHEBI:11638, CHEBI:19748
Supplier Information
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Formula
C5H4O5
Net Charge
-2
Average Mass
144.08226
Monoisotopic Mass
144.00697
InChI
InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)/p-2
InChIKey
KPGXRSRHYNQIFN-UHFFFAOYSA-L
SMILES
[O-]C(=O)CCC(=O)C([O-])=O
Metabolite of Species
Details
Chlamydomonas reinhardtii
(NCBI:txid3055)
See:
PubMed
Saccharomyces cerevisiae
(NCBI:txid4932)
Source: yeast.sf.net See:
PubMed
Homo sapiens
(NCBI:txid9606)
See:
DOI
Roles Classification
Biological Role
(s):
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (
Saccharomyces cerevisiae
).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (
Homo sapiens
).
algal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
Application
(s):
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
2-oxoglutarate(2−) (
CHEBI:16810
)
has functional parent
glutarate(2−) (
CHEBI:30921
)
2-oxoglutarate(2−) (
CHEBI:16810
)
has role
Saccharomyces cerevisiae
metabolite (
CHEBI:75772
)
2-oxoglutarate(2−) (
CHEBI:16810
)
has role
algal metabolite (
CHEBI:84735
)
2-oxoglutarate(2−) (
CHEBI:16810
)
has role
geroprotector (
CHEBI:176497
)
2-oxoglutarate(2−) (
CHEBI:16810
)
has role
human metabolite (
CHEBI:77746
)
2-oxoglutarate(2−) (
CHEBI:16810
)
is a
oxo dicarboxylate (
CHEBI:36147
)
2-oxoglutarate(2−) (
CHEBI:16810
)
is conjugate base of
2-oxoglutarate(1−) (
CHEBI:30916
)
Incoming
2-oxoglutarate(1−) (
CHEBI:30916
)
is conjugate acid of
2-oxoglutarate(2−) (
CHEBI:16810
)
IUPAC Name
2-oxopentanedioate
Synonyms
Sources
2-ketoglutarate
ChEBI
2-oxoglutarate
UniProt
2-oxopentanedioic acid, ion(2−)
ChemIDplus
α-ketoglutarate
ChEBI
Manual Xrefs
Databases
2-KETOGLUTARATE
MetaCyc
C00026
KEGG COMPOUND
View more database links
Registry Numbers
Types
Sources
3664503
Reaxys Registry Number
Reaxys
602479
Gmelin Registry Number
Gmelin
64-15-3
CAS Registry Number
ChemIDplus
Citations
Types
Sources
11913971
PubMed citation
Europe PMC
15612731
PubMed citation
Europe PMC
17190852
PubMed citation
Europe PMC
19376872
PubMed citation
Europe PMC
21184277
PubMed citation
Europe PMC
21196226
PubMed citation
Europe PMC
21791173
PubMed citation
Europe PMC
24828042
PubMed citation
Europe PMC
Last Modified
28 October 2021