A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
Isopropyl unoprostone, marketed under the trade name Rescula (eye drops), is an antihypertensive used for the treatment of open-angle glaucoma and ocular hypertension. A prodrug for the corresponding carboxylic acid, unoprostone, it is believed to reduce intraocular pressure by increasing the outflow of aqueous humor.