ranolazine (CHEBI:87681)

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ChEBI Name	ranolazine

ChEBI ID	CHEBI:87681

Definition	A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.

Stars	This entity has been manually annotated by the ChEBI Team.

Wikipedia	License

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Formula

C24H33N3O4

Net Charge

Average Mass

427.537

Monoisotopic Mass

427.24711

Roles Classification
Biological Role(s):	sodium channel blocker An agent that inhibits sodium influx through cell membranes.

Application(s):	anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.

ChEBI Ontology
Outgoing	ranolazine (CHEBI:87681) has part (R)-ranolazine (CHEBI:87696) ranolazine (CHEBI:87681) has part (S)-ranolazine (CHEBI:87693) ranolazine (CHEBI:87681) has role anti-arrhythmia drug (CHEBI:38070) ranolazine (CHEBI:87681) has role sodium channel blocker (CHEBI:38633) ranolazine (CHEBI:87681) is a racemate (CHEBI:60911)

IUPAC Name

rac-N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide

INN	Source
ranolazine	KEGG DRUG

Synonyms	Sources
(+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide	ChemIDplus
(+-)-Ranolazine	ChemIDplus
(RS)-ranolazine	ChEBI
rac-ranolazine	ChEBI
racemic ranolazine	ChEBI

Brand Name	Source
Ranexa	ChemIDplus

Last Modified

22 February 2017