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InChI=1S/CH4O/c1-2/h2H,1H3
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ChEBI
> Main
CHEBI:85997 - sangivamycin
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ChEBI Ontology
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ChEBI Name
sangivamycin
ChEBI ID
CHEBI:85997
Definition
A nucleoside analogue that is adenosine in which the nitrogen at position 7 is replaced by a carbamoyl-substituted carbon. It is a potent inhibitor of protein kinase C.
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This entity has been manually annotated by the ChEBI Team.
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Formula
C12H15N5O5
Net Charge
0
Average Mass
309.27800
Monoisotopic Mass
309.10732
InChI
InChI=1S/C12H15N5O5/c13-
9-
6-
4(10(14)
21)
1-
17(11(6)
16-
3-
15-
9)
12-
8(20)
7(19)
5(2-
18)
22-
12/h1,3,5,7-
8,12,18-
20H,2H2,(H2,14,21)
(H2,13,15,16)
/t5-
,7-
,8-
,12-
/m1/s1
InChIKey
OBZJZDHRXBKKTJ-JTFADIMSSA-N
SMILES
NC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12
Roles Classification
Biological Role
(s):
protein kinase inhibitor
An EC 2.7.* (
P
-containing group transferase) inhibitor that interferes with the action of protein kinases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
sangivamycin (
CHEBI:85997
)
has functional parent
adenosine (
CHEBI:16335
)
sangivamycin (
CHEBI:85997
)
has role
protein kinase inhibitor (
CHEBI:37699
)
sangivamycin (
CHEBI:85997
)
is a
nucleoside analogue (
CHEBI:60783
)
IUPAC Name
4-
amino-
7-
β-
D
-
ribofuranosyl-
7
H
-
pyrrolo[2,3-
d
]pyrimidine-
5-
carboxamide
Synonyms
Sources
7-Deaza-7-carbamoyladenosine
ChEBI
7-Deazaadenosine-7-carboxamide
ChemIDplus
Registry Numbers
Types
Sources
18417-89-5
CAS Registry Number
ChemIDplus
626355
Reaxys Registry Number
Reaxys
626355
Beilstein Registry Number
ChemIDplus
Citations
Types
Sources
26024233
PubMed citation
Europe PMC
3338987
PubMed citation
Europe PMC
Last Modified
11 June 2015