CHEBI:86989 - stattic

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ChEBI Name stattic ChEBI ID CHEBI:86989 Definition A member of the class of 1-benzothiophenes that is 1-benzothiophene-1,1-dioxide substituted at position 6 by a nitro group. Used as a radiosensitising agent for esophageal squamous cell carcinoma. Stars This entity has been manually annotated by the ChEBI Team. Submitter TheOtherDave Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C8H5NO4S Net Charge 0 Average Mass 211.19500 Monoisotopic Mass 210.99393 InChI InChI=1S/C8H5NO4S/c10-9(11)7-2-1-6-3-4-14(12,13)8(6)5-7/h1-5H InChIKey ZRRGOUHITGRLBA-UHFFFAOYSA-N SMILES [O-][N+](=O)c1ccc2C=CS(=O)(=O)c2c1 Roles Classification Biological Role(s): STAT3 inhibitor An inhibitor of signal transducer and activator of transcription 3 (STAT3) Application(s): radiosensitizing agent A drug that makes increases the sensitivity of tumour cells to radiation therapy. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. View more via ChEBI Ontology ChEBI Ontology Outgoing stattic (CHEBI:86989) has role antineoplastic agent (CHEBI:35610) stattic (CHEBI:86989) has role radiosensitizing agent (CHEBI:132992) stattic (CHEBI:86989) has role STAT3 inhibitor (CHEBI:87183) stattic (CHEBI:86989) is a 1-benzothiophenes (CHEBI:38836) stattic (CHEBI:86989) is a C-nitro compound (CHEBI:35716) stattic (CHEBI:86989) is a sulfone (CHEBI:35850) IUPAC Name 6-nitro-1H-1-benzothiophene-1,1-dione Synonyms Sources 6-nitro-1-benzothiophene 1,1-dioxide SUBMITTER CHEMBL1337170 SUBMITTER STAT3 Inhibitor V SUBMITTER Registry Number Type Source 11410 Reaxys Registry Number Reaxys Citations Types Sources 17114005 PubMed citation Europe PMC 25425624 PubMed citation Europe PMC 25492480 PubMed citation Europe PMC Last Modified 11 August 2016