6-anilino-5,8-quinolinedione (CHEBI:78677)

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ChEBI Name	6-anilino-5,8-quinolinedione

ChEBI ID	CHEBI:78677

Definition	A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C15H10N2O2

Net Charge

Average Mass

250.25210

Monoisotopic Mass

250.07423

InChI

InChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H

InChIKey

GXIJYWUWLNHKNW-UHFFFAOYSA-N

SMILES

O=C1C=C(Nc2ccccc2)C(=O)c2cccnc12

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	EC 4.6.1.2 (guanylate cyclase) inhibitor An EC 4.6.* (P1O lyase) inhibitor that interferes with the action of enzyme guanylate cyclase (EC 4.6.1.2).

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	6-anilino-5,8-quinolinedione (CHEBI:78677) has role antineoplastic agent (CHEBI:35610) 6-anilino-5,8-quinolinedione (CHEBI:78677) has role EC 4.6.1.2 (guanylate cyclase) inhibitor (CHEBI:78678) 6-anilino-5,8-quinolinedione (CHEBI:78677) is a p-quinones (CHEBI:25830) 6-anilino-5,8-quinolinedione (CHEBI:78677) is a aminoquinoline (CHEBI:36709) 6-anilino-5,8-quinolinedione (CHEBI:78677) is a aromatic amine (CHEBI:33860) 6-anilino-5,8-quinolinedione (CHEBI:78677) is a quinolone (CHEBI:23765)

IUPAC Name

6-anilinoquinoline-5,8-dione

Synonyms	Sources
6-(Phenylamino)-5,8-quinolinedione	ChemIDplus
LY 83583	ChemIDplus
LY-83583	ChemIDplus

Last Modified

03 June 2016