CHEBI:75044 - phleomycin

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ChEBI Name phleomycin
ChEBI ID CHEBI:75044
Definition A mixture of glycopeptide antibiotics originally isolated from the bacterium Streptomyces verticillus whose components all contain a thiazolinylthiazole moiety and can form complexes with redox-active metals such as Co, Cu, and Fe. (Bleomycins are very similar to phleomycins, but have a bithiazole moiety in place of the thiazolinylthiazole moiety).
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
mutagen
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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ChEBI Ontology
Outgoing phleomycin (CHEBI:75044) has part phleomycin D1 (CHEBI:75046)
phleomycin (CHEBI:75044) has role antibacterial agent (CHEBI:33282)
phleomycin (CHEBI:75044) has role antimicrobial agent (CHEBI:33281)
phleomycin (CHEBI:75044) has role antineoplastic agent (CHEBI:35610)
phleomycin (CHEBI:75044) has role metabolite (CHEBI:25212)
phleomycin (CHEBI:75044) has role mutagen (CHEBI:25435)
phleomycin (CHEBI:75044) is a mixture (CHEBI:60004)
Synonym Source
phleomycins ChEBI
Manual Xref Database
Phleomycin Wikipedia
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Citations Waiting for Citations Types Sources
13345730 PubMed citation Europe PMC
13672899 PubMed citation Europe PMC
19114524 PubMed citation Europe PMC
19428369 PubMed citation Europe PMC
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6202668 PubMed citation Europe PMC
Last Modified
01 August 2013