8-azahypoxanthine (CHEBI:136532)

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ChEBI Name	8-azahypoxanthine

ChEBI ID	CHEBI:136532

Definition	A triazolopyrimidine that consists of 1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing an oxo substituent at position 7.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C4H3N5O

Net Charge

Average Mass

137.100

Monoisotopic Mass

137.03376

InChI

InChI=1S/C4H3N5O/c10-4-2-3(5-1-6-4)8-9-7-2/h1H,(H2,5,6,7,8,9,10)

InChIKey

OEEYCNOOAHGFHL-UHFFFAOYSA-N

SMILES

C=12C(NC=NC1NN=N2)=O

Roles Classification
Biological Role(s):	antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of hypoxanthine phosphoribosyltransferase (EC 2.4.2.8).

Application(s):	antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.

ChEBI Ontology
Outgoing	8-azahypoxanthine (CHEBI:136532) has role antimalarial (CHEBI:38068) 8-azahypoxanthine (CHEBI:136532) has role EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor (CHEBI:136537) 8-azahypoxanthine (CHEBI:136532) is a nucleobase analogue (CHEBI:67142) 8-azahypoxanthine (CHEBI:136532) is a triazolopyrimidines (CHEBI:48435)

IUPAC Name

1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one

Last Modified

13 March 2017