CHEBI:9368 - swerchirin

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ChEBI Name swerchirin
ChEBI ID CHEBI:9368
Definition A member of the class of xanthones that is the 5-O-methyl derivative of bellidifolin. Isolated from Centaurium erythraea and Swertia chirayita, it exhibits hypoglycemic activity.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:66536
Supplier Information
Download Molfile XML SDF
Formula C15H12O6
Net Charge 0
Average Mass 288.25220
Monoisotopic Mass 288.06339
InChI InChI=1S/C15H12O6/c1-19-7-5-9(17)12-11(6-7)21-15-10(20-2)4-3-8(16)13(15)14(12)18/h3-6,16-17H,1-2H3
InChIKey GNSHHHWDGOHNPC-UHFFFAOYSA-N
SMILES COc1cc(O)c2c(c1)oc1c(OC)ccc(O)c1c2=O
Metabolite of Species Details
Canscora lucidissima (IPNI:366566-1) See: PubMed
Gentiana bellidifolia (IPNI:367849-1) See: DOI
Gentiana karelini (IPNI:368363-1) See: DOI
Gentiana lactea (IPNI:368388-1) See: PubMed
Swertia gracilescens (IPNI:370915-1) See: PubMed
Swertia longifolia (IPNI:370964-1) Found in aerial part (BTO:0001658). See: PHARM BIOL,2003,41,497
Swertia patens (IPNI:371018-1) See: YUNNAN ZHIWU YANJIU,1982,4,68
Swertia sp.ciosa (IPNI:371090-1) See: BULL MUS NATL HIST NAT PARIS,1977,13,55
Swertia tetrapetala (IPNI:371108-1) See: PubMed
Swertia chirata (IPNI:60447539-2) Found in root (BTO:0001188). See: DOI
Swertia chirata (IPNI:60447539-2) Found in aerial part (BTO:0001658). See: DOI
Frasera albicaulis (NCBI:txid137093) Found in root (BTO:0001188). See: DOI
Swertia japonica (NCBI:txid137129) See: DOI
Swertia racemosa (NCBI:txid137132) See: PubMed
Swertia mussotii (NCBI:txid137888) See: DOI
Swertia bimaculata (NCBI:txid148627) Found in whole plant (BTO:0001461). See: DOI
Frasera albomarginata (NCBI:txid166602) Found in root (BTO:0001188). See: DOI
Swertia calycina (NCBI:txid166613) Found in whole plant (BTO:0001461). See: DOI
Centaurium erythraea (NCBI:txid172057) Found in root (BTO:0001188). See: DOI
Centaurium pulchellum (NCBI:txid172069) Found in whole plant (BTO:0001461). See: DOI
Centaurium littorale (NCBI:txid225562) Found in root (BTO:0001188). See: DOI
Centaurium cachanlahuen (NCBI:txid225565) See: DOI
Swertia mileensis (NCBI:txid266086) Found in whole plant (BTO:0001461). Air dried whole plant See: PubMed
Swertia nervosa (NCBI:txid363513) See: PubMed
Swertia petiolata (NCBI:txid39380) Found in aerial part (BTO:0001658). See: DOI
Frasera caroliniensis (NCBI:txid485363) Found in root (BTO:0001188). See: DOI
Gentiana algida (NCBI:txid50748) See: DOI
Comastoma pulmonarium (NCBI:txid50754) See: ZHIWU XUEBAO,1988,30,303
Swertia franchetiana (NCBI:txid50785) See: DOI
Swertia dilatata (NCBI:txid559635) See: PubMed
Swertia paniculata (NCBI:txid559637) See: DOI
Blackstonia perfoliata (NCBI:txid82736) Found in aerial part (BTO:0001658). See: DOI
Swertia chirayita (NCBI:txid993650) Hexane extract of Swertia chirayita See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): hypoglycemic agent
A drug which lowers the blood glucose level.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing swerchirin (CHEBI:9368) has functional parent bellidifolin (CHEBI:3008)
swerchirin (CHEBI:9368) has role hypoglycemic agent (CHEBI:35526)
swerchirin (CHEBI:9368) has role metabolite (CHEBI:25212)
swerchirin (CHEBI:9368) is a aromatic ether (CHEBI:35618)
swerchirin (CHEBI:9368) is a phenols (CHEBI:33853)
swerchirin (CHEBI:9368) is a xanthones (CHEBI:51149)
IUPAC Name
1,8-dihydroxy-3,5-dimethoxy-9H-xanthen-9-one
Synonyms Sources
1,8-Dihydroxy-3,5-dimethoxyxanthone ChEBI
3,5-Dimethoxy-1,8-dihydroxyxanthone KEGG COMPOUND
5-O-Methylbellidifolin KEGG COMPOUND
methylbellidifolin ChEBI
Swerchirin KEGG COMPOUND
Manual Xrefs Databases
C00002973 KNApSAcK
C10091 KEGG COMPOUND
IN179769 Patent
View more database links
Registry Numbers Types Sources
313581 Reaxys Registry Number Reaxys
521-65-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12575167 PubMed citation Europe PMC
1891489 PubMed citation Europe PMC
19260313 PubMed citation Europe PMC
Last Modified
28 July 2014
General Comments
2012-07-27 BULL MUS NATL HIST NAT PARIS,1977,13,55
2012-07-27 YUNNAN ZHIWU YANJIU,1982,4,68
2012-07-27 PHARM BIOL,2003,41,497
2012-07-27 ZHIWU XUEBAO,1988,30,303