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> Main
CHEBI:31941 - oxaliplatin
Main
ChEBI Ontology
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ChEBI Name
oxaliplatin
ChEBI ID
CHEBI:31941
Definition
A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer.
Stars
This entity has been manually annotated by the ChEBI Team.
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Wikipedia
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Read full article at Wikipedia
Formulae
C6H14N2.C2O4.Pt
C8H14N2O4Pt
Net Charge
0
Average Mass
397.28584
Monoisotopic Mass
397.06015
InChI
InChI=1S/C6H14N2.C2H2O4.Pt/c7-
5-
3-
1-
2-
4-
6(5)
8;3-
1(4)
2(5)
6;/h5-
6H,1-
4,7-
8H2;(H,3,4)
(H,5,6)
;/q;;+2/p-
2/t5-
,6-
;;/m1../s1
InChIKey
ZROHGHOFXNOHSO-BNTLRKBRSA-L
SMILES
[H][N]1([H])[C@@H]2CCCC[C@H]2[N]([H])([H])[Pt]11OC(=O)C(=O)O1
Roles Classification
Biological Role
(s):
mutagen
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
Application
(s):
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
oxaliplatin (
CHEBI:31941
)
has role
antineoplastic agent (
CHEBI:35610
)
oxaliplatin (
CHEBI:31941
)
has role
mutagen (
CHEBI:25435
)
oxaliplatin (
CHEBI:31941
)
is a
platinum coordination entity (
CHEBI:33862
)
Incoming
cucurbit[7]uril—oxaliplatin (
CHEBI:51436
)
has part
oxaliplatin (
CHEBI:31941
)
IUPAC Name
(
SP
-
4-
2)[(1
R
,2
R
)-
cyclohexane-
1,2-
diamine-
κ
2
N
,
N
'][ethanedioato(2−)-
κ
2
O
1
,
O
2
]platinum
INNs
Sources
oxaliplatin
KEGG DRUG
oxaliplatine
ChEBI
oxaliplatino
DrugBank
oxaliplatinum
DrugBank
Synonyms
Sources
(
SP
-
4-
2-
(1
R
-
trans
))-
(1,2-
cyclohexanediamine-
N
,
N
')(ethanedioato(2−)-
O
,
O
')platinum
ChemIDplus
oxalato(1,2-diaminocyclohexane)platinum(
II
)
ChemIDplus
Oxaliplatin
KEGG COMPOUND
Brand Name
Source
Eloxatin
KEGG DRUG
Manual Xrefs
Databases
D01790
KEGG DRUG
DB00526
DrugBank
LSM-6352
LINCS
Oxaliplatin
Wikipedia
View more database links
Registry Numbers
Types
Sources
1046012
Gmelin Registry Number
Gmelin
15700099
Reaxys Registry Number
Reaxys
28892
Gmelin Registry Number
Gmelin
61825-94-3
CAS Registry Number
KEGG COMPOUND
63121-00-6
CAS Registry Number
ChemIDplus
Citations
Types
Sources
11300320
PubMed citation
Europe PMC
14755010
PubMed citation
Europe PMC
15477639
PubMed citation
Europe PMC
17347561
PubMed citation
Europe PMC
18440088
PubMed citation
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19138416
PubMed citation
Europe PMC
19735649
PubMed citation
Europe PMC
27756654
PubMed citation
Europe PMC
28186109
PubMed citation
Europe PMC
28398406
PubMed citation
Europe PMC
28415810
PubMed citation
Europe PMC
28499428
PubMed citation
Europe PMC
28505615
PubMed citation
Europe PMC
28624791
PubMed citation
Europe PMC
28642473
PubMed citation
Europe PMC
28654098
PubMed citation
Europe PMC
28695397
PubMed citation
Europe PMC
28762171
PubMed citation
Europe PMC
28777427
PubMed citation
Europe PMC
28800641
PubMed citation
Europe PMC
28811232
PubMed citation
Europe PMC
28812173
PubMed citation
Europe PMC
28837658
PubMed citation
Europe PMC
28876454
PubMed citation
Europe PMC
28881354
PubMed citation
Europe PMC
28881481
PubMed citation
Europe PMC
28884286
PubMed citation
Europe PMC
28894576
PubMed citation
Europe PMC
28924870
PubMed citation
Europe PMC
28938919
PubMed citation
Europe PMC
Last Modified
26 September 2017