thioflavine T (CHEBI:76023)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	thioflavine T

ChEBI ID	CHEBI:76023

Definition	An organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Margaret Duesbury

Secondary ChEBI IDs	CHEBI:88013

Supplier Information

Download	Molfile XML SDF

more structures >>

Wikipedia	License

Read full article at Wikipedia

Formula

C17H19ClN2S

Net Charge

Average Mass

318.866

Monoisotopic Mass

318.09575

InChI

InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1

InChIKey

JADVWWSKYZXRGX-UHFFFAOYSA-M

SMILES

C=1(C=2C=CC(N(C)C)=CC2)SC=3C=C(C)C=CC3[N+]1C.[Cl-]

Roles Classification
Application(s):	fluorochrome A fluorescent dye used to stain biological specimens. histological dye A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.

ChEBI Ontology
Outgoing	thioflavine T (CHEBI:76023) has part thioflavin T cation (CHEBI:76034) thioflavine T (CHEBI:76023) has role fluorochrome (CHEBI:51217) thioflavine T (CHEBI:76023) has role geroprotector (CHEBI:176497) thioflavine T (CHEBI:76023) has role histological dye (CHEBI:77178) thioflavine T (CHEBI:76023) is a organic chloride salt (CHEBI:36094)

IUPAC Name

2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride

Synonyms	Sources
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzothiazolium chloride	ChemIDplus
basic yellow 1	ChEBI
C.I. 49005	ChEBI
C.I. Basic Yellow 1	ChemIDplus
Thioflavin T	ChemIDplus
ThT	SUBMITTER

Last Modified

28 October 2021