CHEBI:66526 - strongylin A

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ChEBI Name strongylin A
ChEBI ID CHEBI:66526
Definition A sesquiterpenoid that is 1,2,3,4,4a,5,6,7,7a,8-decahydrobenzo[d]xanthene substituted by a hydroxy group at position 12, methyl groups at positions 4, 4, 7 and 7a and a methoxy group at position 9 (the 4aS,7S,7aR,13aS stereoisomer). Isolated from Strongylophora hartmani, it exhibits activity against the influenza virus.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C22H32O3
Net Charge 0
Average Mass 344.48770
Monoisotopic Mass 344.23514
InChI InChI=1S/C22H32O3/c1-14-7-10-18-20(2,3)11-6-12-22(18)21(14,4)13-15-17(24-5)9-8-16(23)19(15)25-22/h8-9,14,18,23H,6-7,10-13H2,1-5H3/t14-,18-,21+,22-/m0/s1
InChIKey AHDRBWCUVQGBTR-DNEUNLEDSA-N
SMILES [H][C@@]12CC[C@H](C)[C@@]3(C)Cc4c(OC)ccc(O)c4O[C@@]13CCCC2(C)C
Metabolite of Species Details
Strongylophora hartmani (WORMS:194087) See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing strongylin A (CHEBI:66526) has role antineoplastic agent (CHEBI:35610)
strongylin A (CHEBI:66526) has role EC 3.2.1.18 (exo-α-sialidase) inhibitor (CHEBI:52425)
strongylin A (CHEBI:66526) has role metabolite (CHEBI:25212)
strongylin A (CHEBI:66526) is a aromatic ether (CHEBI:35618)
strongylin A (CHEBI:66526) is a organic heterotetracyclic compound (CHEBI:38163)
strongylin A (CHEBI:66526) is a phenols (CHEBI:33853)
strongylin A (CHEBI:66526) is a sesquiterpenoid (CHEBI:26658)
IUPAC Name
(4aS,7S,7aR,13aS)-9-methoxy-4,4,7,7a-tetramethyl-1,2,3,4,4a,5,6,7,7a,8-decahydrobenzo[d]xanthen-12-ol
Registry Number Type Source
136978-48-8 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
1791476 PubMed citation Europe PMC
Last Modified
09 July 2013