CHEBI:64162 - N-methylquipazine dimaleate

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ChEBI Name N-methylquipazine dimaleate
ChEBI ID CHEBI:64162
ChEBI ASCII Name N-methylquipazine dimaleate
Definition A maleate salt obtained by reaction of N-methylquipazine with two equivalents of maleic acid. A 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C22H25N3O8
Net Charge 0
Average Mass 459.44920
Monoisotopic Mass 459.16416
InChI InChI=1S/C14H17N3.2C4H4O4/c1-16-8-10-17(11-9-16)14-7-6-12-4-2-3-5-13(12)15-14;2*5-3(6)1-2-4(7)8/h2-7H,8-11H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
InChIKey HNSITEGFVDCKMF-SPIKMXEPSA-N
SMILES [H+].[H+].[H+].[H+].[O-]C(=O)\C=C/C([O-])=O.[O-]C(=O)\C=C/C([O-])=O.CN1CCN(CC1)c1ccc2ccccc2n1
Roles Classification
Biological Role(s): serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Application(s): prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
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ChEBI Ontology
Outgoing N-methylquipazine dimaleate (CHEBI:64162) has part N-methylquipazine (CHEBI:64164)
N-methylquipazine dimaleate (CHEBI:64162) has role prodrug (CHEBI:50266)
N-methylquipazine dimaleate (CHEBI:64162) has role serotonergic agonist (CHEBI:35941)
N-methylquipazine dimaleate (CHEBI:64162) is a maleate salt (CHEBI:50221)
IUPAC Name
2-(4-methylpiperazin-1-yl)quinoline di[(2Z)-but-2-enedioate]
Synonyms Sources
2-(4-methylpiperazin-1-yl)quinoline dimaleate ChEBI
2-(4-methylpiperazin-1-yl)quinoline maleate ChEBI
N-methylquipazine maleate ChEBI
Registry Number Type Source
7614127 Reaxys Registry Number Reaxys
Last Modified
12 March 2012