CHEBI:33270 - α-tocotrienol

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ChEBI Name α-tocotrienol
ChEBI ID CHEBI:33270
ChEBI ASCII Name alpha-tocotrienol
Definition A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a farnesyl chain at position 2. It has been found in palm oil derived from Elaeis guineensis.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:35062
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Formula C29H44O2
Net Charge 0
Average Mass 424.65846
Monoisotopic Mass 424.33413
InChI InChI=1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1
InChIKey RZFHLOLGZPDCHJ-XZXLULOTSA-N
SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1
Metabolite of Species Details
Panax ginseng (NCBI:txid4054) From MetaboLights See: MetaboLights Study
Homo sapiens (NCBI:txid9606) See: DOI
Homo sapiens (NCBI:txid9606) Found in blood (UBERON:0000178). See: PubMed
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
(via vitamin E )
(via tocol )
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
ferroptosis inhibitor
Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
fat-soluble vitamin (role)
Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess.
(via vitamin E )
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing α-tocotrienol (CHEBI:33270) has role ferroptosis inhibitor (CHEBI:173084)
α-tocotrienol (CHEBI:33270) has role human metabolite (CHEBI:77746)
α-tocotrienol (CHEBI:33270) has role neuroprotective agent (CHEBI:63726)
α-tocotrienol (CHEBI:33270) has role plant metabolite (CHEBI:76924)
α-tocotrienol (CHEBI:33270) is a tocotrienol (CHEBI:33235)
α-tocotrienol (CHEBI:33270) is a vitamin E (CHEBI:33234)
IUPAC Name
(2R)-2,5,7,8-tetramethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-chromen-6-ol
Synonyms Sources
(2R)-2,5,7,8-tetramethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-1-benzopyran-6-ol IUPAC
alpha-tocotrienol LIPID MAPS
alpha-tocotrienol KEGG COMPOUND
α-tocotrienol UniProt
α-tocotrienol ChemIDplus
zeta1-tocopherol LIPID MAPS
ζ1-tocopherol ChemIDplus
Manual Xrefs Databases
4445512 ChemSpider
Alpha-Tocotrienol Wikipedia
C00035044 KNApSAcK
C14153 KEGG COMPOUND
CPD-15836 MetaCyc
EP2362875 Patent
FDB002434 FooDB
HMDB0006327 HMDB
LMPR02020054 LIPID MAPS
US2010105930 Patent
WO2010051277 Patent
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Registry Numbers Types Sources
1721-51-3 CAS Registry Number KEGG COMPOUND
1721-51-3 CAS Registry Number ChemIDplus
45723 Beilstein Registry Number Beilstein
5484296 Beilstein Registry Number Beilstein
5484296 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
26 July 2021