CHEBI:73755 - 1,2-dimethylhydrazine

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ChEBI Name 1,2-dimethylhydrazine
ChEBI ID CHEBI:73755
Definition A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C2H8N2
Net Charge 0
Average Mass 60.09830
Monoisotopic Mass 60.06875
InChI InChI=1S/C2H8N2/c1-3-4-2/h3-4H,1-2H3
InChIKey DIIIISSCIXVANO-UHFFFAOYSA-N
SMILES CNNC
Roles Classification
Biological Role(s): carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
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ChEBI Ontology
Outgoing 1,2-dimethylhydrazine (CHEBI:73755) has role alkylating agent (CHEBI:22333)
1,2-dimethylhydrazine (CHEBI:73755) has role carcinogenic agent (CHEBI:50903)
1,2-dimethylhydrazine (CHEBI:73755) is a hydrazines (CHEBI:24631)
1,2-dimethylhydrazine (CHEBI:73755) is conjugate base of 1,2-dimethylhydrazine(2+) (CHEBI:73760)
Incoming 1,2-dimethylhydrazine(2+) (CHEBI:73760) is conjugate acid of 1,2-dimethylhydrazine (CHEBI:73755)
IUPAC Name
1,2-dimethylhydrazine
Synonyms Sources
(CH3NH)2 NIST Chemistry WebBook
(MeNH)2 ChEBI
1,2-Dimethylhydrazin ChemIDplus
1,2-DMH ChemIDplus
DMH ChemIDplus
hydrazomethane NIST Chemistry WebBook
MeNHNHMe ChEBI
N,N'-dimethylhydrazine ChEBI
SDMH ChemIDplus
sym-dimethylhydrazine ChemIDplus
symmetrical-dimethylhydrazine ChemIDplus
Manual Xrefs Databases
1,2-dimethylhydrazine Wikipedia
C19176 KEGG COMPOUND
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Registry Numbers Types Sources
1730826 Reaxys Registry Number Reaxys
540-73-8 CAS Registry Number KEGG COMPOUND
540-73-8 CAS Registry Number ChemIDplus
540-73-8 CAS Registry Number NIST Chemistry WebBook
Citation Waiting for Citations Type Source
21193881 PubMed citation Europe PMC
Last Modified
22 May 2013