7,3',4'-trihydroxy-3,8-dimethoxyflavone (CHEBI:69452)

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ChEBI Name	7,3',4'-trihydroxy-3,8-dimethoxyflavone

ChEBI ID	CHEBI:69452

Definition	A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 7, 3' and 4' and methoxy groups at positions 3 and 8. Isolated from Mimosa diplotricha, it exhibits cytotoxic activity against human cancer cell lines.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C17H14O7

Net Charge

Average Mass

330.28890

Monoisotopic Mass

330.07395

InChI

InChI=1S/C17H14O7/c1-22-16-11(19)6-4-9-13(21)17(23-2)14(24-15(9)16)8-3-5-10(18)12(20)7-8/h3-7,18-20H,1-2H3

InChIKey

LLXQONIKJLTKCF-UHFFFAOYSA-N

SMILES

COc1c(O)ccc2c1oc(-c1ccc(O)c(O)c1)c(OC)c2=O

Metabolite of Species	Details
Mimosa diplotricha (NCBI:txid512270)	Found in aerial part (BTO:0001658). Ethanolic extract of aerial part See: PubMed

Roles Classification
Biological Role(s):	metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	7,3',4'-trihydroxy-3,8-dimethoxyflavone (CHEBI:69452) has functional parent flavone (CHEBI:42491) 7,3',4'-trihydroxy-3,8-dimethoxyflavone (CHEBI:69452) has role antineoplastic agent (CHEBI:35610) 7,3',4'-trihydroxy-3,8-dimethoxyflavone (CHEBI:69452) has role metabolite (CHEBI:25212) 7,3',4'-trihydroxy-3,8-dimethoxyflavone (CHEBI:69452) is a catechols (CHEBI:33566) 7,3',4'-trihydroxy-3,8-dimethoxyflavone (CHEBI:69452) is a dimethoxyflavone (CHEBI:23798) 7,3',4'-trihydroxy-3,8-dimethoxyflavone (CHEBI:69452) is a trihydroxyflavone (CHEBI:27116)

IUPAC Name

2-(3,4-dihydroxyphenyl)-7-hydroxy-3,8-dimethoxy-4H-chromen-4-one

Registry Number	Type	Source
1329302	Reaxys Registry Number	Reaxys

Citation	Type	Source
21875046	PubMed citation	Europe PMC

Last Modified

20 March 2018