CHEBI:37560 - benproperine

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ChEBI Name benproperine
ChEBI ID CHEBI:37560
Definition A racemate comprising equimolar amounts of (R)- and (S)-benproperine. It is used as a cough suppressant in non-productive cough.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Application(s): antitussive
An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
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ChEBI Ontology
Outgoing benproperine (CHEBI:37560) has part (R)-benproperine (CHEBI:78388)
benproperine (CHEBI:37560) has part (S)-benproperine (CHEBI:78389)
benproperine (CHEBI:37560) has role antitussive (CHEBI:51177)
benproperine (CHEBI:37560) is a racemate (CHEBI:60911)
IUPAC Name
rac-1-[1-(2-benzylphenoxy)propan-2-yl]piperidine
INNs Sources
benproperina WHO MedNet
benpropérine WHO MedNet
benproperine WHO MedNet
benproperinum WHO MedNet
Synonyms Sources
(±)-benproperine ChEBI
1-[2-(2-benzylphenoxy)-1-methylethyl]piperidine ChemIDplus
1-{1-methyl-2-[(α-phenyl-o-tolyl)oxy]ethyl}piperidine ChemIDplus
rac-benproperine ChEBI
Manual Xrefs Databases
Benproperine Wikipedia
D07512 KEGG DRUG
GB914008 Patent
US3117059 Patent
View more database links
Registry Numbers Types Sources
1258822 Reaxys Registry Number Reaxys
2156-27-6 CAS Registry Number NIST Chemistry WebBook
2156-27-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12567913 PubMed citation Europe PMC
12567915 PubMed citation Europe PMC
15005888 PubMed citation Europe PMC
16280263 PubMed citation Europe PMC
16297353 PubMed citation Europe PMC
Last Modified
29 April 2014