CHEBI:79548 - L-365260

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name L-365260
ChEBI ID CHEBI:79548
Stars This entity has been manually annotated by a third party.
Supplier Information
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Formula C24H22N4O2
Net Charge 0
Average Mass 398.45710
Monoisotopic Mass 398.17428
InChI InChI=1S/C24H22N4O2/c1-16-9-8-12-18(15-16)25-24(30)27-22-23(29)28(2)20-14-7-6-13-19(20)21(26-22)17-10-4-3-5-11-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1
InChIKey KDFQABSFVYLGPM-QFIPXVFZSA-N
SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
Application(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing L-365260 (CHEBI:79548) is a benzodiazepine (CHEBI:22720)
Synonym Source
N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea KEGG COMPOUND
Manual Xref Database
C15026 KEGG COMPOUND
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Registry Number Type Source
118101-09-0 CAS Registry Number KEGG COMPOUND