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M  END
> <ID>
CHEBI:41879

> <NAME>
dexamethasone

> <DEFINITION>
A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of  glucocorticoids.

> <STAR>
3

> <SECONDARY_ID>
CHEBI:41873; CHEBI:4461

> <SYNONYM>
fluormethylprednisolone; dexamethasone; Dexamethasone; 9alpha-fluoro-16alpha-methylprednisolone; 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol; 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone; (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

> <IUPAC_NAME>
9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

> <INN>
dexamethasonum; dexamethasone; dexamethasone; dexametasona

> <BRAND_NAME>
Zema-Pak; Solurex; Ozurdex; Oradexon; Millicorten; Maxidex; Hexadrol; Diodex; DexPak; Dexasone; Dexason; Dexacortin; Dexacortal; Decameth; Decalix; Decaject; Decadron; Decacort; Cortisumman; Corson; Calonat; Azium; Auxiron; Aeroseb-Dex

> <FORMULA>
C22H29FO5

> <MASS>
392.467

> <MONOISOTOPIC_MASS>
392.19990

> <CHARGE>
0

> <SMILES>
C1=CC(C=C2[C@]1([C@@]3([C@@](CC2)([C@]4([C@](C[C@@H]3O)([C@]([C@@H](C4)C)(C(CO)=O)O)C)[H])[H])F)C)=O

> <INCHI>
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

> <INCHIKEY>
UREBDLICKHMUKA-CXSFZGCWSA-N

> <BEILSTEIN_REGISTRY_NUMBER>
2066652

> <CAS_REGISTRY_NUMBER>
50-02-2

> <REAXYS_REGISTRY_NUMBER>
2066652

> <CHEMIDPLUS>
50-02-2

> <DRUGBANK_ACCESSION>
DB01234

> <KEGG_COMPOUND_ACCESSION>
C15643

> <KEGG_DRUG_ACCESSION>
D00292

> <METACYC_ACCESSION>
CPD-10549

> <NIST_CHEMISTRY_WEBBOOK>
50-02-2

> <WIKIPEDIA_ACCESSION>
Dexamethasone

> <PUBMED_CITATION>
11508649; 12151000; 12686538; 18272184; 18524938; 19779450; 20850457; 26602186; 29958267; 31391291; 32195984; 32280693; 32496907; 32551464; 32570995

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