Marvin 07181311422D 47 51 0 0 0 0 999 V2000 22.1812 -29.0697 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 23.7803 -33.1615 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 24.3182 -31.9494 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 22.4620 -33.0232 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 25.7766 -34.3106 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 26.4424 -35.4615 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 24.4461 -34.3123 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 22.1849 -31.7299 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 23.3352 -31.0644 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 25.7776 -36.6140 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.5733 -34.0185 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 25.6159 -31.6798 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 23.7819 -35.4646 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 26.4409 -33.1583 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 26.4431 -37.7643 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 24.4476 -36.6154 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.0326 -31.0656 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 23.3338 -29.7344 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.0309 -29.7351 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 26.7824 -27.7503 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.9778 -27.7490 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 22.1848 -27.7483 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 17.5774 -27.7490 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 16.4255 -27.0842 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 23.3276 -27.0872 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 26.7846 -29.0805 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.9778 -29.0779 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.0323 -27.0835 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.7294 -27.0842 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 19.8820 -27.7490 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.1210 -27.0842 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 25.6307 -27.0857 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 24.4798 -27.7515 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.2729 -27.7490 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.0309 -25.7535 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 18.7294 -25.7547 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 25.6338 -29.7462 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.1210 -29.7427 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.2729 -29.0779 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 24.4812 -29.0815 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 27.9332 -27.0845 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 11.8259 -27.0842 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 27.9364 -29.7450 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 11.8259 -29.7427 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 11.8259 -25.7547 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 27.9318 -25.7545 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 19.8834 -29.0790 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3 2 1 0 0 0 0 4 2 1 0 0 0 0 7 2 1 0 0 0 0 9 3 1 0 0 0 0 12 3 2 0 0 0 0 8 4 1 0 0 0 0 11 4 2 0 0 0 0 7 5 1 0 0 0 0 6 5 1 0 0 0 0 14 5 2 0 0 0 0 10 6 1 0 0 0 0 13 7 1 0 0 0 0 17 8 1 0 0 0 0 9 8 2 0 0 0 0 18 9 1 0 0 0 0 16 10 1 0 0 0 0 15 10 2 0 0 0 0 16 13 1 0 0 0 0 19 17 2 0 0 0 0 1 18 2 0 0 0 0 19 1 1 0 0 0 0 26 20 1 0 0 0 0 32 20 2 0 0 0 0 41 20 1 0 0 0 0 31 21 2 0 0 0 0 42 21 1 0 0 0 0 27 21 1 0 0 0 0 25 22 2 0 0 0 0 28 22 1 0 0 0 0 29 23 1 0 0 0 0 24 23 2 0 0 0 0 34 24 1 0 0 0 0 33 25 1 0 0 0 0 37 26 2 0 0 0 0 43 26 1 0 0 0 0 38 27 2 0 0 0 0 44 27 1 0 0 0 0 30 28 1 0 0 0 0 35 28 2 0 0 0 0 30 29 1 0 0 0 0 36 29 2 0 0 0 0 34 31 1 0 0 0 0 33 32 1 0 0 0 0 40 33 2 0 0 0 0 39 34 2 0 0 0 0 40 37 1 0 0 0 0 39 38 1 0 0 0 0 46 41 1 0 0 0 0 45 42 1 0 0 0 0 30 47 2 0 0 0 0 19 47 1 0 0 0 0 M END > CHEBI:74775 > 5-(2,2-diferuloylethen-1-yl)thalidomide > A dicarboximide that is thalidomide substituted at position 5 by an ethenyl group, which in turn is substituted by two feruloyl groups at position 2. The compound is a hybrid based on the structures of thalidomide and curcumin and has been found to exhibit cytotoxicity against human multiple myeloma cells. > 3 > 5-{2,2-di[(1E)-1-(4-hydroxy-3-methoxyphenyl)-3-oxoprop-1-en-3-yl]ethenyl}thalidomide; 5-{(4E)-5-(4-hydroxy-3-methoxyphenyl)-2-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-3-oxopenta-1,4-dien-1-yl}thalidomide > 2-(2,6-dioxopiperidin-3-yl)-5-{(4E)-5-(4-hydroxy-3-methoxyphenyl)-2-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-3-oxopenta-1,4-dien-1-yl}-1H-isoindole-1,3(2H)-dione > C35H28N2O10 > 636.60420 > 636.17440 > 0 > COc1cc(\C=C\C(=O)C(=Cc2ccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3c2)C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O > InChI=1S/C35H28N2O10/c1-46-30-17-19(6-12-28(30)40)4-10-26(38)24(27(39)11-5-20-7-13-29(41)31(18-20)47-2)16-21-3-8-22-23(15-21)35(45)37(34(22)44)25-9-14-32(42)36-33(25)43/h3-8,10-13,15-18,25,40-41H,9,14H2,1-2H3,(H,36,42,43)/b10-4+,11-5+ > RNAMRGODNOWOJL-ZVSIBQGLSA-N > 23784627 $$$$