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tetrodotoxin |
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CHEBI:9506 |
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A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels. |
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This entity has been manually annotated by the ChEBI Team.
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Molfile
XML
SDF
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more structures >>
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InChI=1S/C11H17N3O8/c12- 8- 13- 6(17) 2- 4- 9(19,1- 15) 5- 3(16) 10(2,14- 8) 7(18) 11(20,21- 4) 22- 5/h2- 7,15- 20H,1H2,(H3,12,13,14) /t2- ,3+,4- ,5+,6- ,7+,9+,10- ,11+/m1/s1 |
CFMYXEVWODSLAX-QYIGHCJRSA-N |
OC[C@@]1(O)[C@H]2O[C@@]3(O)O[C@@H]1[C@@H]1[C@@H](O)NC(=N)N[C@]1([C@H]2O)[C@@H]3O |
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marine metabolite
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
animal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
voltage-gated sodium channel blocker
Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels.
neurotoxin
A poison that interferes with the functions of the nervous system.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
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View more via ChEBI Ontology
(1R,5R,6R,7R,9S,11R,12R,13S,14S)- 14- (hydroxymethyl)- 3- imino- 8,10- dioxa- 2,4- diazatetracyclo[7.3.1.17,11.01,6]tetradecane- 5,9,12,13,14- pentol
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fugu poison
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ChemIDplus
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maculotoxin
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ChemIDplus
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octahydro- 12- (hydroxymethyl)- 2- imino- 5,9:7,10a- dimethano- 10aH- [1,3]dioxocino[6,5- d]pyrimidine- 4,7,10,11,12- pentol
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ChEBI
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spheroidine
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ChemIDplus
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tarichatoxin
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ChemIDplus
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tetrodontoxin
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ChemIDplus
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Tetrodotoxin
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KEGG COMPOUND
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TTX
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KEGG COMPOUND
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TTX
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ChemIDplus
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4156319
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Beilstein Registry Number
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Beilstein
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4368-28-9
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CAS Registry Number
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ChemIDplus
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6072946
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Reaxys Registry Number
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Reaxys
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22163187
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PubMed citation
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Europe PMC
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22412801
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PubMed citation
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Europe PMC
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22798951
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PubMed citation
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Europe PMC
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23261990
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Europe PMC
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23661608
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Europe PMC
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23866757
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Europe PMC
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23980434
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24121556
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Europe PMC
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24295175
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PubMed citation
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Europe PMC
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24566728
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PubMed citation
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Europe PMC
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28817087
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PubMed citation
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Europe PMC
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