CHEBI:49668 - gefitinib

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ChEBI Name gefitinib
ChEBI ID CHEBI:49668
Definition A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:38917, CHEBI:49667
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): epidermal growth factor receptor antagonist
An antagonist at the epidermal growth factor receptor.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
gefitinib is a Functional Parent of
linkable gefitinib analogue
Mass : 376.81238
Formula : C18H18ClFN4O2
39084
gefitinib is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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