CHEBI:18258 - 3,3',5-triiodo-L-thyronine

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ChEBI Name 3,3',5-triiodo-L-thyronine
ChEBI ID CHEBI:18258
ChEBI ASCII Name 3,3',5-triiodo-L-thyronine
Definition An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:11701, CHEBI:45840, CHEBI:11702, CHEBI:9722, CHEBI:13059, CHEBI:19894
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): thyroid hormone
Any hormone produced by the thyroid gland
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
Related Structures
3,3',5-triiodo-L-thyronine is a Functional Parent of
3,3',5-triiodo-L-thyronine sulfate
Mass : 731.03773
Formula : C15H12I3NO7S
35432
3,3',5-triiodo-L-thyronine has Substituent Group(s)
3,3',5-triiodo-L-thyronine residue
Mass : 632.959
Formula : C15H10I3NO3
90874
3,3',5-triiodo-L-thyronine is a Structural Derivative of
thyronine
Mass : 273.28394
Formula : C15H15NO4
30661 		ammonia
Mass : 17.03056
Formula : H3N
16134
3,3',5-triiodo-L-thyronine is a Conjugate Acid of
3,3',5-triiodo-L-thyroninate
Mass : 649.96560
Formula : C15H11I3NO4
60308
3,3',5-triiodo-L-thyronine is a Tautomer of
3,3',5-triiodo-L-thyronine zwitterion
Mass : 650.97350
Formula : C15H12I3NO4
533015
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