CHEBI:66005 - N2-methylharmine

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ChEBI Name N2-methylharmine
ChEBI ID CHEBI:66005
ChEBI ASCII Name N(2)-methylharmine
Definition A member of the class of β-carbolines that is 9H-β-carboline substituted by a methoxy group at position 7 and methyl groups at positions 1 and 2. It is a semisynthetic derivative of harmine and has been shown to exhibit significant anti-HIV activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C14H14N2O
Net Charge 0
Average Mass 226.27380
Monoisotopic Mass 226.11061
InChI InChI=1S/C14H14N2O/c1-9-14-12(6-7-16(9)2)11-5-4-10(17-3)8-13(11)15-14/h4-8H,1-3H3
InChIKey SNPOLGTUMADPOR-UHFFFAOYSA-N
SMILES COc1ccc2c(c1)nc1c(C)n(C)ccc21
Roles Classification
Biological Role(s): anti-HIV agent
An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing N2-methylharmine (CHEBI:66005) has functional parent harmine (CHEBI:28121)
N2-methylharmine (CHEBI:66005) has role anti-HIV agent (CHEBI:64946)
N2-methylharmine (CHEBI:66005) is a β-carbolines (CHEBI:60834)
N2-methylharmine (CHEBI:66005) is a aromatic ether (CHEBI:35618)
N2-methylharmine (CHEBI:66005) is a semisynthetic derivative (CHEBI:72588)
IUPAC Name
7-methoxy-1,2-dimethyl-2H-β-carboline
Synonym Source
7-methoxy-1,2-dimethyl-2H-pyrido[3,4-b]indole ChEBI
Registry Numbers Types Sources
15521 Reaxys Registry Number Reaxys
6519-18-2 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
11473435 PubMed citation Europe PMC
Last Modified
10 May 2016