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CHEBI:84612 - 8-(4-chlorophenylthio)-cAMP
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ChEBI Name
8-(4-chlorophenylthio)-cAMP
ChEBI ID
CHEBI:84612
Definition
A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP in which the hydrogen at position 2 on the purine fragment is replaced by a 4-chlorophenylthio group.
Stars
This entity has been manually annotated by the ChEBI Team.
Submitter
Margaret Duesbury
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Formula
C16H15ClN5O6PS
Net Charge
0
Average Mass
471.81200
Monoisotopic Mass
471.01692
InChI
InChI=1S/C16H15ClN5O6PS/c17-
7-
1-
3-
8(4-
2-
7)
30-
16-
21-
10-
13(18)
19-
6-
20-
14(10)
22(16)
15-
11(23)
12-
9(27-
15)
5-
26-
29(24,25)
28-
12/h1-
4,6,9,11-
12,15,23H,5H2,(H,24,25)
(H2,18,19,20)
/t9-
,11-
,12-
,15-
/m1/s1
InChIKey
AAZMHPMNAVEBRE-SDBHATRESA-N
SMILES
Nc1ncnc2n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c(Sc3ccc(Cl)cc3)nc12
Roles Classification
Biological Role
(s):
protein kinase agonist
An agonist that selectively binds to and activates a protein kinase receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
8-(4-chlorophenylthio)-cAMP (
CHEBI:84612
)
has functional parent
3',5'-cyclic AMP (
CHEBI:17489
)
8-(4-chlorophenylthio)-cAMP (
CHEBI:84612
)
has role
protein kinase agonist (
CHEBI:64106
)
8-(4-chlorophenylthio)-cAMP (
CHEBI:84612
)
is a
3',5'-cyclic purine nucleotide (
CHEBI:19834
)
8-(4-chlorophenylthio)-cAMP (
CHEBI:84612
)
is a
adenyl ribonucleotide (
CHEBI:61296
)
8-(4-chlorophenylthio)-cAMP (
CHEBI:84612
)
is a
aryl sulfide (
CHEBI:35683
)
8-(4-chlorophenylthio)-cAMP (
CHEBI:84612
)
is a
organochlorine compound (
CHEBI:36683
)
IUPAC Name
(4a
R
,6
R
,7
R
,7a
S
)-
6-
{6-
amino-
8-
[(4-
chlorophenyl)sulfanyl]-
9
H
-
purin-
9-
yl}-
2,7-
dihydroxytetrahydro-
2
H
,4
H
-
2λ
5
-
furo[3,2-
d
][1,3,2]dioxaphosphinin-
2-
one
Synonyms
Sources
8-((4-Chlorophenyl)thio)cyclic-3',5'-amp
ChemIDplus
8-(4-chlorophenylthio)-3',5'-cyclic AMP
ChEBI
8-(4-chlorophenylthio)-cyclic AMP
ChEBI
8-(4-chlorophenylthio)adenosine cyclic 3',5'-phosphate
ChEBI
8-CPT-cAMP
ChEBI
8-Parachlorophenylthio camp
ChemIDplus
Registry Numbers
Types
Sources
41941-66-6
CAS Registry Number
ChemIDplus
598763
Reaxys Registry Number
Reaxys
Citations
Types
Sources
23382200
PubMed citation
Europe PMC
24586238
PubMed citation
Europe PMC
24605759
PubMed citation
SUBMITTER
Last Modified
23 March 2015