CHEBI:6704 - mebendazole

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ChEBI Name mebendazole
ChEBI ID CHEBI:6704
Definition A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C16H13N3O3
Net Charge 0
Average Mass 295.29284
Monoisotopic Mass 295.09569
InChI InChI=1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)
InChIKey OPXLLQIJSORQAM-UHFFFAOYSA-N
SMILES COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1ccccc1
Roles Classification
Biological Role(s): tubulin modulator
Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
microtubule-destabilising agent
Any substance that interacts with tubulin to inhibit polymerisation of microtubules.
Application(s): antinematodal drug
A substance used in the treatment or control of nematode infestations.
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ChEBI Ontology
Outgoing mebendazole (CHEBI:6704) has parent hydride 1H-benzimidazole (CHEBI:41275)
mebendazole (CHEBI:6704) has role antinematodal drug (CHEBI:35444)
mebendazole (CHEBI:6704) has role microtubule-destabilising agent (CHEBI:61951)
mebendazole (CHEBI:6704) has role tubulin modulator (CHEBI:60832)
mebendazole (CHEBI:6704) is a aromatic ketone (CHEBI:76224)
mebendazole (CHEBI:6704) is a benzimidazoles (CHEBI:22715)
mebendazole (CHEBI:6704) is a carbamate ester (CHEBI:23003)
IUPAC Name
methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate
Synonyms Sources
(5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester ChemIDplus
MBDZ ChemIDplus
Mebendazole KEGG COMPOUND
Vermox ChemIDplus
Manual Xrefs Databases
1641 DrugCentral
D00368 KEGG DRUG
DB00643 DrugBank
LSM-3749 LINCS
Mebendazole Wikipedia
View more database links
Registry Numbers Types Sources
31431-39-7 CAS Registry Number ChemIDplus
759809 Beilstein Registry Number Beilstein
759809 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
6126101 PubMed citation Europe PMC
Last Modified
22 February 2017