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EBI DbfetchID Z93767; SV 1; linear; genomic DNA; STD; PRO; 15218 BP. XX AC Z93767; XX DT 07-APR-1997 (Rel. 51, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 7) XX DE B.subtilis DNA; 15.2 kb fragment, from ywqN gene to ywrO gene XX KW acetolactate operon; alpha-acetolactate decarboxylase; KW alpha-acetolactate synthase protein; alsD gene; alsR gene; alsS gene; KW cotB gene; cotG gene; spore coat protein B; spore coat protein G; KW transcriptional regulatory protein; ywqN gene; ywqO gene; ywrA gene; KW ywrB gene; ywrC gene; ywrD gene; ywrE gene; ywrF gene; ywrH gene; KW ywrJ gene; ywrK gene; ywrO gene. XX OS Bacillus subtilis OC Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus. XX RN [1] RP 1-15218 RA Presecan E., Moszer I., Hullo M., Danchin A., Glaser P.; RT "The Bacillus subtilis genome from gerBC to licR"; RL Unpublished. XX RN [2] RP 5311-6209 RX PUBMED; 7814326. RA Sacco M., Ricca E., Losick R., Cutting S.; RT "An additional GerE-controlled gene encoding an abundant spore coat protein RT from Bacillus subtilis"; RL J. Bacteriol. 177(2):372-377(1995). XX RN [3] RP 10080-14588 RX PUBMED; 7685336. RA Renna M.C., Najimudin N., Winik L.R., Zahler S.A.; RT "Regulation of the Bacillus subtilis alsS, alsD, and alsR genes involved in RT post-exponential-phase production of acetoin"; RL J. Bacteriol. 175(12):3863-3875(1993). XX RN [4] RP 1-15218 RA Glaser P.; RT ; RL Submitted (05-APR-1997) to the EMBL/GenBank/DDBJ databases. RL Philippe Glaser, Regulation de l'Expression Genetique, Institut Pasteur, 28 RL Rue du Dr Roux, Paris, 75724, FRANCE XX RN [5] RP 1-15218 RX PUBMED; 9353933. RA Presecan E., Moszer I., Boursier L., Cruz H., De La Fuente V., Hullo M.F., RA Lelong C., Schleich S., Sekowska A., Song B.H., Villani G., Kunst F., RA Danchin A., Glaser P.; RT "The Bacillus subtilis genome from gerBC (311degree) to licR (334degree)"; RL Microbiology (Reading, Engl.) 143:3313-3328(1997). XX FH Key Location/Qualifiers FH FT source 1..15218 FT /organism="Bacillus subtilis" FT /strain="168" FT /mol_type="genomic DNA" FT /db_xref="taxon:1423" FT CDS <1..418 FT /codon_start=2 FT /transl_table=11 FT /gene="ywqN" FT /db_xref="GOA:P96726" FT /db_xref="InterPro:IPR005025" FT /db_xref="PDB:1RLI" FT /db_xref="UniProtKB/Swiss-Prot:P96726" FT /protein_id="CAB07794.1" FT /translation="DLRHAQGGFRPVQDDYDSIIERILQCHILIFATPIYWFGMSGTLK FT LFIDRWSQTLRDPRFPDFKQQMSVKQAYVIAVGGDNPKIKGLPLIQQFEHIFHFMGMSF FT KGYVLGEGNRPGDILRDHQALSAASRLLKRSDAI" FT RBS 400..410 FT /gene="ywqO" FT CDS 415..636 FT /transl_table=11 FT /gene="ywqO" FT /db_xref="UniProtKB/Swiss-Prot:P96727" FT /protein_id="CAB07795.1" FT /translation="MKFLLSVIAGLLILALYLFWKVQPPVWIQVETNSSQLKQSVRMAG FT TTLQVKHMIKSDAGEETAVISNGISGLK" FT terminator 631..666 FT /gene="ywqO" FT CDS complement(663..1199) FT /transl_table=11 FT /gene="ywrA" FT /note="similar to chromate transport protein, ChrA" FT /db_xref="GOA:O05215" FT /db_xref="InterPro:IPR003370" FT /db_xref="UniProtKB/Swiss-Prot:O05215" FT /protein_id="CAB07796.1" FT /translation="MISIYLFMAFFIANLLGYGGGPASIPLMFEEVVNRYSWLSNDQFS FT NMLALANALPGPIATKIAAYVGYSAGGWPGFLIALIATVVPSALALIVLLRIIQRFRQS FT PVIKGMTLSVQPVIAVMMLILTWQIGADGIKAIGWVQSIVITGISLLAMTKFKMHPAFL FT IIAAFLYGGLVIPYL" FT RBS complement(1208..1215) FT /gene="ywrA" FT CDS complement(1196..1789) FT /transl_table=11 FT /gene="ywrB" FT /note="similar to chromate transport protein, ChrA" FT /db_xref="GOA:O05216" FT /db_xref="InterPro:IPR003370" FT /db_xref="UniProtKB/Swiss-Prot:O05216" FT /protein_id="CAB07797.1" FT /translation="MKNHPYRDMTAAMVRTGILGFGGGPSVIPLIRHEAVNKYKWIDDD FT EFGEILAIANALPGPIATKMAAYLGFKLKGTLGAIVAILAHILPTCLAMVGLFAAVNVL FT SHSAIVAGMIGAVTPVIAVMLGIMAYEFGQKALKGFGWVTGILFFIIAFIGLQTLQINP FT GLVIIIFLAYGAFHFKLKDKITNKHSKDKGMSAS" FT RBS complement(1796..1803) FT /gene="ywrB" FT CDS complement(1803..2279) FT /transl_table=11 FT /gene="ywrC" FT /note="similar to leucine regulatory protein, Lrp and AsnC FT protein that regulates expression of asnA gene which FT encodes asparagine synthetase A" FT /db_xref="GOA:O05217" FT /db_xref="HSSP:1I1G" FT /db_xref="InterPro:IPR000485" FT /db_xref="InterPro:IPR011008" FT /db_xref="InterPro:IPR011991" FT /db_xref="InterPro:IPR013199" FT /db_xref="InterPro:IPR019887" FT /db_xref="InterPro:IPR019888" FT /db_xref="UniProtKB/Swiss-Prot:O05217" FT /protein_id="CAB07798.1" FT /translation="MSHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAV FT QARINQLIEAGVIEKFTAVINPAKIGIHVSVFFNVEVEPQFLEEVALKLEEEPAVTSLY FT HMTGPSKLHMHGIFTNDQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL" FT RBS complement(2286..2294) FT /gene="ywrC" FT RBS 2480..2490 FT /gene="ywrD" FT CDS 2493..4070 FT /transl_table=11 FT /gene="ywrD" FT /note="similar to gamma glutamyl transpeptidase precursor, FT GGT protein" FT /db_xref="GOA:O05218" FT /db_xref="HSSP:2DG5" FT /db_xref="InterPro:IPR000101" FT /db_xref="UniProtKB/Swiss-Prot:O05218" FT /protein_id="CAB07790.1" FT /translation="MNKSVIGTKQMVVSPHYLASQAGNRILDKGGNAFDAAVAVSACLA FT VVYPHMTGLGGDSFWLTFHQETKAVKVYNGSGRSGKNVTRDVYKGKSAIPLRGIDSAIT FT VPGMVDSWDAVLKEYGRLSLADVLEPARDYAQNGFPVSADQCRHTEKNIELLASTPYTA FT DIFTRRGKAPVPGERFVQKELADSLNLIAEKGRSAFYEGDLAQRIVSHLQNNGSYMTID FT DFKAHRGEWAAPVSSDYRGYSVYQAPPNSQGFTGLLTLNILENYDFTQIEHGSFEYYHV FT LVEALKKSFLDRDAVLTDPAFADIPLERLLDKRYAKQLAEEIGYLAIPAESRPVGSDTA FT YAAVIDADGNAVSFIQSLYFEFGSAVTAGDTGILLQNRGSFFSLDENHVNTLEPRKRTF FT HTLMPAMVCKGGKPKILYGTQGGEGQPQTQTAIITRMLDYGMHPQQAISEPRWVWGRTW FT GEEYEGLRVEGRFTDKTIQKLKDSGHLVEVVGDYDPLMGQAAAIKVDEEGFLQGGADPR FT GDGAAVGI" FT CDS complement(4075..4410) FT /transl_table=11 FT /gene="ywrE" FT /db_xref="GOA:O05219" FT /db_xref="UniProtKB/Swiss-Prot:O05219" FT /protein_id="CAB07791.1" FT /translation="MTNFWILMLIAITISLASQFFIKKKYGIDKSGWRYKHVSNTHKWI FT EITLLILFVFSLSFFPVEYLLLLFFIVIDSIRIFMEWHYRPEDKQYMYHIVEVSLMFML FT LIYVCTL" FT RBS complement(4413..4423) FT /gene="ywrE" FT stem_loop 4463..4498 FT CDS complement(4588..5205) FT /transl_table=11 FT /gene="ywrF" FT /db_xref="GOA:O05220" FT /db_xref="InterPro:IPR002563" FT /db_xref="InterPro:IPR009002" FT /db_xref="InterPro:IPR012349" FT /db_xref="UniProtKB/Swiss-Prot:O05220" FT /protein_id="CAB07792.1" FT /translation="MYIFQADQLSAKDTYKLLSGTVIPRPIAFVTTLSSGGAVNAAPFS FT FYNVVSSDPPLLSISVNRTEGRQKDTARNAVENGEFVVHVSDEAIIEDINETAASLRPD FT ESELTRTSLHPVESKAVSVPGIKEARVRFECKLERHITFDNDQGITTADLLIGRVVCFH FT LDEKVYDAEKGYILTDELKPASRLAGNHYAKLGEEFTLIRPS" FT RBS complement(5211..5220) FT /gene="ywrF" FT terminator complement(5327..5359) FT /gene="cotG" FT CDS complement(5379..5966) FT /transl_table=11 FT /gene="cotG" FT /product="spore coat protein G, CotG" FT /db_xref="GOA:P39801" FT /db_xref="UniProtKB/Swiss-Prot:P39801" FT /protein_id="CAB07799.1" FT /translation="MGHYSHSDIEEAVKSAKKEGLKDYLYQEPHGKKRSHKKSHRTHKK FT SRSHKKSYCSHKKSRSHKKSFCSHKKSRSHKKSYCSHKKSRSHKKSYRSHKKSRSYKKS FT YRSYKKSRSYKKSCRSYKKSRSYKKSYCSHKKKSRSYKKSCRTHKKSYRSHKKYYKKPH FT HHCDDYKRHDDYDSKKEYWKDGNCWVVKKKYK" FT RBS complement(5973..5981) FT /gene="cotG" FT RBS 6093..6101 FT /gene="ywrH" FT CDS 6107..7195 FT /transl_table=11 FT /gene="ywrH" FT /db_xref="GOA:Q45535" FT /db_xref="InterPro:IPR014867" FT /db_xref="UniProtKB/Swiss-Prot:Q45535" FT /protein_id="CAB07793.1" FT /translation="MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDI FT DIAYRGSHIRDFKKKSYHISFYQPKTFRGAREIHLNAEYKDPSLMRNKLSLDFFSELGT FT LSPKAEFAFVKMNGKNEGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSDLER FT ETKTSLELGYEKKTGTEEDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIV FT FTSNYDGFVHNYALYRSGETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTAR FT ILDESEFRKSYKRLLEKTLQSLFTIEYMEPKIMAMYERIRPFVLMDPYKKNDIERFDRE FT PDVICEYIKNRSQYLKDHLSIL" FT RBS 7310..7318 FT /gene="cotB" FT CDS 7323..8465 FT /transl_table=11 FT /gene="cotB" FT /product="spore coat protein B, CotB" FT /db_xref="GOA:P07789" FT /db_xref="UniProtKB/Swiss-Prot:P07789" FT /protein_id="CAB07789.1" FT /translation="MSKRRMKYHSNNEISYYNFLHSMKDKIVTVYRGGPESKKGKLTAV FT KSDYIALQAEKKIIYYQLEHVKSITEDTNNSTTTIETEEMLDADDFHSLIGHLINQSVQ FT FNQGGPESKKGRLVWLGDDYAALNTNEDGVVYFNIHHIKSISKHEPDLKIEEQTPVGVL FT EADDLSEVFKSLTHKWVSINRGGPEAIEGILVDNADGHYTIVKNQEVLRIYPFHIKSIS FT LGPKGSYKKEDQKNEQNQEDNNDKDSNSFISSKSYSSSKSSKRSLKSSDDQSSKSGRSS FT RSKSSSKSSKRSLKSSDYQSSKSGRSSRSKSSSKSSKRSLKSSDYQSSKSSKRSPRSSD FT YQSSRSPGYSSSIKSSGKQKEDYSYETIVRTIDYHWKRKF" FT RBS 8512..8520 FT /gene="ywrJ" FT CDS 8525..9202 FT /transl_table=11 FT /gene="ywrJ" FT /db_xref="InterPro:IPR020173" FT /db_xref="UniProtKB/Swiss-Prot:O05223" FT /protein_id="CAB07800.1" FT /translation="MKGLNQFLNTDVEVVISGDTRFVGTLIDIGQDIFVIFDGCNYLYI FT PLLHLHQINKAKIVTSTEKPFLINPEDPMIEAETQAFSYRNTLNKVKGQFIEVYVTGGR FT SIHGYVTNVLNDYIVFFSPVFKILFISMHHLKWFTPYSTEQTPYTLDNSQLPVVPSKVP FT LVRNFEEQIKKNIGELVIFDMGEVPEKVGLLKGVSNNIIELINASGEPVIWKLNHLKTM FT HLP" FT terminator 9210..9243 FT /gene="ywrJ" FT CDS complement(9259..10587) FT /transl_table=11 FT /gene="ywrK" FT /note="similar to ArsB integral membrane protein presumably FT containing the arsenate-arsenite-antimony transmembrane FT channel" FT /db_xref="GOA:O05224" FT /db_xref="InterPro:IPR000802" FT /db_xref="UniProtKB/Swiss-Prot:O05224" FT /protein_id="CAB07801.1" FT /translation="MLAFFVTMIFIFWRPKGLNEAIPATFGALMVLLCGSVSLADLGEI FT GTKVTGASVTILATMIMAIALESFGFFYWVAAKLLQQSKGSGIKLFWLTNLLCFLMTIF FT LNNDGSILITTPILLLVLKYLGLKKHQKAPYLLSGVLIATASSAPIGVSNIVNLISLKI FT IGMDLYLHTAMMFVPSMMGLIFMTCLLFMFFYKRLPKSLPDIPGHFQSLRHRRYHPLHS FT PSAPLPERNQTKIMLFVLAFVFLVRMSLFAASYTGISVPLVAVIGSFILLSWRWIYFKT FT SPRDLLYKSPWHIFIFAFTMYVLIYGLHNIGFTELLVSYFEPVVSGSLAHATFASGIST FT SVFSNLFNNHPALMISTFTLTEMTLNPSTTKIIYLANIIGSDIGSLLLPMGTLATLIWM FT HILKQHDESISWGEYIKTTIIIIPLTVLFTLTCLYFWISWLFL" FT RBS complement(10595..10602) FT /gene="ywrK" FT CDS complement(10798..11706) FT /transl_table=11 FT /gene="alsR" FT /product="transcriptional regulatory protein of the FT acetolactate operon, AlsR" FT /db_xref="GOA:Q04778" FT /db_xref="InterPro:IPR000847" FT /db_xref="InterPro:IPR005119" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:Q04778" FT /protein_id="CAB07788.1" FT /translation="MELRHLQYFIAVAEELHFGKAARRLNMTQPPLSQQIKQLEEEVGV FT TLLKRTKRFVELTAAGEIFLNHCRMALMQIGQGIELAQRTARGEQGLLVIGFVGSATYE FT FLPPIVREYRKKFPSVKIELREISSSRQQEELLKGNIDIGILHPPLQHTALHIETAQSS FT PCVLALPKQHPLTSKESITIEDLRDEPIITVAKEAWPTLYMDFIQFCEQAGFRPNIVQE FT ATEYQMVIGLVSAGIGMTFVPSSAKKLFNLDVTYRKMDQIQLNAEWVIAYRKDNHNPLI FT KHFIHISNCQQTRTKESDAGT" FT RBS complement(11715..11727) FT /gene="alsR" FT RBS 11850..11857 FT /gene="alsS" FT CDS 11861..13576 FT /transl_table=11 FT /gene="alsS" FT /product="alpha-acetolactate synthase protein, AlsS" FT /db_xref="GOA:Q04789" FT /db_xref="InterPro:IPR000399" FT /db_xref="InterPro:IPR011766" FT /db_xref="InterPro:IPR012000" FT /db_xref="InterPro:IPR012001" FT /db_xref="InterPro:IPR012782" FT /db_xref="UniProtKB/Swiss-Prot:Q04789" FT /protein_id="CAB07802.1" FT /translation="MLTKATKEQKSLVKNRGAELVVDCLVEQGVTHVFGIPGAKIDAVF FT DALQDKGPEIIVARHEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNLATGLLTANTEGD FT PVVALAGNVIRADRLKRTHQSLDNAALFQPITKYSVEVQDVKNIPEAVTNAFRIASAGQ FT AGAAFVSFPQDVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAKLPVVLVGMKG FT GRPEAIKAVRKLLKKVQLPFVETYQAAGTLSRDLEDQYFGRIGLFRNQPGDLLLEQADV FT VLTIGYDPIEYDPKFWNINGDRTIIHLDEIIADIDHAYQPDLELIGDIPSTINHIEHDA FT VKVEFAEREQKILSDLKQYMHEGEQVPADWKSDRAHPLEIVKELRNAVDDHVTVTCDIG FT SHAIWMSRYFRSYEPLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDGGFLFSA FT MELETAVRLKAPIVHIVWNDSTYDMVAFQQLKKYNRTSAVDFGNIDIVKYAESFGATGL FT RVESPDQLADVLRQGMNAEGPVIIDVPVDYSDNINLASDKLPKEFGELMKTKAL" FT RBS 13621..13628 FT /gene="alsD" FT CDS 13638..14405 FT /transl_table=11 FT /gene="alsD" FT /product="alpha-acetolactate decarboxylase protein, AlsD" FT /db_xref="GOA:Q04777" FT /db_xref="InterPro:IPR005128" FT /db_xref="UniProtKB/Swiss-Prot:Q04777" FT /protein_id="CAB07786.1" FT /translation="MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEI FT PKYGDFGIGTFNKLDGELIGFDGEFYRLRSDGTATPVQNGDRSPFCSFTFFTPDMTHKI FT DAKMTREDFEKEINSMLPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKTQPI FT FNFDNVRGTIVGFLTPAYANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMN FT MNLRLPNTADFFNANLDNPDFAKDIETTEGSPE" FT terminator 14407..14449 FT /gene="alsD" FT RBS 14492..14500 FT /gene="ywrO" FT CDS 14505..15032 FT /transl_table=11 FT /gene="ywrO" FT /note="similar to hypothetical NAD(P)H oxidoreductase FT protein" FT /db_xref="GOA:P80871" FT /db_xref="InterPro:IPR003680" FT /db_xref="UniProtKB/Swiss-Prot:P80871" FT /protein_id="CAB07787.1" FT /translation="MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAI FT DVAKEQQLCEEYDRIVFQFPLYWYSSPPLLKKWQDLVLTYGWAFGSEGNALHGKELMLA FT VSTGSEAEKYQAGGANHYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDISHSA FT KRLAEYIQQPFV" FT terminator 15032..15069 FT /gene="ywrO" FT conflict 6026..6028 FT /replace="cggc" FT /citation=[2] FT conflict 10214..10222 FT /replace="aaaatatttt" FT /citation=[3] FT conflict 11761..11766 FT /replace="aaggtcgaa" FT /citation=[3] FT conflict 12052..12060 FT /replace="agcaattcat" FT /citation=[3] FT conflict 12205..12213 FT /replace="tgcatatcg" FT /citation=[3] FT conflict 13061..13067 FT /replace="cactcca" FT /citation=[3] FT conflict 13306..13320 FT /replace="catggtgcatttcca" FT /citation=[3] FT conflict 13402..13412 FT /replace="aactgcgttgc" FT /citation=[3] XX SQ Sequence 15218 BP; 4615 A; 2960 C; 3422 G; 4221 T; 0 other; agatctgcgt cacgcccaag gcggctttcg tcctgttcaa gatgactacg attctatcat 60 tgaacggata ttgcagtgcc atattcttat attcgccacc ccaatttatt ggtttggcat 120 gtcagggaca ttaaagctgt ttattgatcg ctggtcacag acgttgagag atccgagatt 180 tcctgatttt aaacagcaaa tgtcagtgaa acaggcatat gtaatagcag tgggcggaga 240 caatccaaaa ataaaagggc tgccgctgat tcagcaattc gaacatattt ttcattttat 300 gggaatgtcc tttaaaggct atgtgctggg agaaggcaat cgtccaggcg atattcttcg 360 tgatcatcag gcgctgtccg ctgcgagccg cttactgaaa agaagcgatg cgatatgaag 420 tttttgctgt cggtcattgc tggcttgctg attcttgcac tctatttatt ttggaaggtc 480 cagcctcctg tttggataca agttgaaacc aattcgtccc agttgaagca atctgtgaga 540 atggcaggaa ccacgctgca agtcaagcac atgatcaaga gtgacgcagg agaagaaaca 600 gctgtcatat caaacggcat ttctgggcta aaataaaaaa gcacctgtcc aggtgctttt 660 ttctataaat aagggatcac aaggccccca tataaaaacg ccgcaataat caaaaatgcc 720 ggatgcattt tgaattttgt catggcaagg agcgaaattc ccgtaatcac gatcgattgg 780 acccagccga tcgctttgat gccgtctgcg ccgatttgcc aggtaagaat gagcatcatg 840 accgcgatga caggctggac ggacagcgtc atgcctttga tgacaggtga ttggcggaag 900 cgctggatga tgcgcagcag gacgatcaat gcgagcgccg acggtacgac ggttgcgatc 960 agggcaatta ggaagccggg ccacccgcct gcgctgtagc cgacatacgc agcgattttc 1020 gtggcgatcg ggcccggcaa tgcgttcgca agtgcgagca tatttgagaa ttgatcgttt 1080 gagagccagc tgtatctgtt tacgacttct tcaaacatta gcgggataga cgcaggtccg 1140 ccgccatatc ccagtaggtt tgcgataaaa aacgccataa ataaatagat cgatatcatg 1200 aggctgacat tcctttatct tttgaatgtt tatttgtgat tttgtctttc agtttaaaat 1260 gaaacgcccc gtaagctaag aaaatgataa tgaccaggcc gggattaatc tgtaaagttt 1320 gcaggccgat aaaagcgatg ataaaaaaca ggatgccggt aacccagccg aaacctttaa 1380 gcgctttttg gccaaactcg tacgccatga ttccgagcat gaccgcaatt accggcgtga 1440 cggcaccaat catacctgca acaattgctg aatggcttaa cacatttaca gccgcaaaca 1500 agcccaccat cgcaagacat gtaggcagaa tgtgggcgag gatcgccaca attgcaccta 1560 atgtgccttt tagcttaaag cccagataag cagccatttt ggtggcaatc ggtccgggaa 1620 gcgcattagc gattgctaat atttctccga attcatcatc gtcaatccat ttatatttat 1680 tgaccgcttc atggcggatc agcggaatca cggaaggtcc gccgccgaac cctaatatgc 1740 cggtgcgaac cattgcggcc gtcatatccc gataaggatg gtttttcatt tgtttctctc 1800 ctttacagct tcattcccat acggcttttg tatcgtttga tcagcatctg gcaatcaaca 1860 ctgacgacgc ctcgcaatgg atacagccgt tttgttaaga attcttccat ttcttgatcg 1920 ttggtaaaga tcccatgcat atgcagcttg ctcgggcctg tcatgtgata aaggctggtg 1980 accgcaggct cttcctcaag cttaagagcg acctcttcta aaaattgcgg ttctacctcg 2040 acattgaaaa acacggaaac atggatgccg attttagcgg gattgatgac agcggtgaat 2100 ttttcaataa caccggcttc aattaattgg ttgatacggg cctgaacggc gacccgtgac 2160 aaatcgactc ttttgccaag atccgtataa gaaattctgc cttcttcatg caaaatcgtg 2220 agaatttgtt tatcagtctc atcaagtaca aggttgggga tttgatattc atgactcaat 2280 tgctccacct gctttcgtag ccttttagca atcattttat cataaaagtt acgtatagaa 2340 ataataattt ttcatttgtt ttcgaaatga atgcgaaaat atcttattat ttgcgaaaag 2400 aagaaagttc gtcagttttt ctgccggatc agtagatgtg aaaaatcagg ctccctatac 2460 tgaagaaaat ttcttaaaaa aggggacttg tgatgaacaa atctgtcatc ggtacaaagc 2520 aaatggtcgt cagtccgcat tatctcgctt ctcaagccgg aaaccgcata ctggataagg 2580 gaggcaacgc gtttgacgcc gctgttgcgg tgagtgcttg tcttgcggtt gtgtacccgc 2640 atatgaccgg acttggcggg gattcctttt ggctgacctt tcaccaggaa acaaaggcag 2700 taaaagtcta caatggcagc ggccgttcag gaaaaaacgt aacgagagat gtatataagg 2760 gaaaaagcgc gattccgctg cggggaattg acagtgctat taccgtgccg ggaatggttg 2820 atagctggga tgcggtcctg aaggagtacg ggcgtctgtc tcttgcagat gtattggagc 2880 ccgcacgcga ttatgcccaa aatgggtttc ctgtatcagc tgatcagtgt cgtcacacag 2940 aaaagaatat tgaactgctg gcttccacgc cttacacggc tgacatcttc acgagaaggg 3000 gcaaagcacc tgtcccggga gagcggtttg tgcaaaaaga gcttgcagac agtctgaact 3060 tgattgctga aaaaggaaga agcgcatttt atgaaggaga tctcgctcag cggattgtct 3120 cacatttaca gaataacggc agttacatga caatcgatga ttttaaagcg catcggggtg 3180 agtgggcagc gcctgtatca agtgattatc gaggatacag tgtgtatcag gcgccgccga 3240 attctcaggg atttaccggt ttattaacac tgaacatttt ggaaaactat gatttcaccc 3300 aaatcgaaca cggttcattt gagtattatc acgtgcttgt ggaggcattg aaaaagagtt 3360 ttctagatcg ggatgccgtc ctgactgatc cggcgtttgc agacattccg cttgaaaggc 3420 ttttggacaa acgttatgca aaacaattgg cagaagaaat cggctatctc gcaataccgg 3480 cagaaagcag gccggtggga agtgatacgg catatgcggc cgtaatcgat gcggatggca 3540 acgcagtgtc attcattcaa agcctgtact ttgaatttgg ctcggcagtc actgccggtg 3600 atacaggcat attactgcaa aaccgcggat cgtttttctc actggatgaa aatcatgtca 3660 acacgcttga accgagaaag cgcaccttcc atacgttgat gccggctatg gtctgtaaag 3720 gcggaaagcc aaaaattctg tacggcacac aaggcggcga aggccagccg cagacccaga 3780 cggccatcat tacccgaatg ctggactacg gaatgcatcc acagcaggca atcagcgaac 3840 cgcgctgggt atggggcaga acgtggggag aggaatacga aggtctcaga gtcgagggca 3900 gattcacaga caaaacaatc caaaaactga aagacagcgg gcatctcgtg gaggttgtcg 3960 gtgactatga tccgctgatg ggacaagcgg ctgcaatcaa agttgatgaa gaaggctttc 4020 tccaaggcgg agccgatcct cggggagacg gagcggctgt ggggatttaa ataactatag 4080 ggtacaaaca taaatcaaaa gcataaacat aagggagacc tctacaatgt ggtacatata 4140 ctgtttatct tcaggtctat aatgccactc cataaaaata cgtattgagt caatcacaat 4200 aaaaaataaa agaagcaaat attcaactgg aaaaaaggag agtgaaaaca caaacaaaat 4260 aagtaaagtg atttcgatcc atttgtgtgt attgctgaca tgcttatatc gccagccgga 4320 tttatcaata ccgtattttt tctttataaa aaattgagag gcgagactga tggtaatagc 4380 gatcagcatt aaaatccaaa agtttgtcat tccaattcct cctaatctac ctttatacga 4440 agaaaaagga aaaacgtttc ataaaagaac accccgagct tgctctgggt gttctttttt 4500 ttgatatttt ttcagttatt tacaggcgat attttgtaat cataaggtct ttttgactag 4560 tttcttctat ttaaatagtc cttctcttca gctgggacga atcagtgtga attcttcccc 4620 cagcttggca tagtgatttc ccgccaatcg tgaggcaggc tttaattcat ccgttaaaat 4680 atatcccttt tctgcatcat acaccttttc atctaggtgg aagcagacaa ctcttccgat 4740 gagcagatct gctgtagtga tgccttgatc attgtcaaag gtaatatgcc gctctaattt 4800 gcactcaaag cgaacgcggg cttccttaat gccgggaact gaaacagctt tgctttcaac 4860 aggatgaagc gaggtgcgtg taagctcgct ttcatccggc cttaagcttg cagctgtttc 4920 attgatatct tcaatgatgg cttcatcact gacatgaacg acaaattctc cgttctccac 4980 tgcgtttcgt gctgtatctt tttggcgtcc ttccgtcctg ttaacagaaa tactgagaag 5040 cggaggatct gagctgacga cgttataaaa actgaaaggc gcggcattta ccgctcctcc 5100 tgaagaaagt gttgtcacaa atgcaatggg gcggggaata acggtacctg acaatagctt 5160 gtatgtgtct ttggcactaa gctgatcagc ttgaaatatg tacatagcaa caaccgcctt 5220 tatcgttagg ataccttgat tataacgaaa tggtttaaag gaaaccaaat gatgcgggtt 5280 gcatatgtta tgtcatgaca tatatctaat acagggcaaa taaaaaaata ggcttccgta 5340 cctccgccgg cagcctattg aaacaatgaa aacttagatt atttgtattt ctttttgact 5400 acccagcaat tgccgtcttt ccagtattct tttttgctgt cataatcatc gtgtcttttg 5460 tagtcgtcgc agtggtggtg cggttttttg tagtatttct tatgggaacg ataagatttt 5520 ttgtgtgtgc ggcatgactt cttatagctg cgagattttt tcttgtgaga acagtaagac 5580 tttttgtagc tgcgagattt tttgtaagaa cggcaagatt ttttatagct acgagatttt 5640 ttgtaagaac ggtaagattt tttatagctg cgagattttt tgtgagaacg gtacgatttt 5700 ttgtggctgc gagatttctt gtgagagcag tatgattttt tgtggctgcg agattttttg 5760 tgagaacaga atgatttttt gtgactgcga gattttttgt gagagcagta tgatttttta 5820 tggctgcgag attttttgtg agtgcggtgc gactttttat gactgcgttt ttttccatga 5880 ggctcttggt ataaataatc ctttaaacct tctttttttg cggatttcac cgcttcttcg 5940 atgtcagaat gggaatagtg gcccaatttg aaatcctcct tttaaaaata tgttaaggat 6000 gaagatcctt actaccctca tagtacgcgc ggttttaaaa agtgtataag tgttccgctg 6060 agatcttata aaaataaaag cctaaaattt gtaaggagga ttatggatga agaatcaatc 6120 caatttaccg ctttatcagc tgtttgttca tccaaaagac ttgcgtgaat taaaaaagga 6180 tatatgggac gatgatccgg tgccagctgt gatgaaggta aatcaaaaaa ggctggatat 6240 tgatatcgct tatcggggat cacatatcag agacttcaaa aagaagtcat accatatttc 6300 cttttatcag ccgaaaacat tccgcggcgc gcgagagatt cacttaaatg cggagtataa 6360 agacccttcc ttgatgagaa acaaattgtc tctggatttt ttctcggagc tagggacact 6420 gtctccaaag gcagagtttg cgtttgtaaa gatgaatggg aagaatgaag gggtttatct 6480 tgaacttgaa tccgtagatg aatattattt ggcgaaaagg aagctggctg atggcgcgat 6540 tttttatgcg gtggatgatg atgccaactt ttctctgatg agcgatttag aaagggaaac 6600 gaaaacatcg ctggagcttg gatatgaaaa gaaaacaggg actgaggaag atgattttta 6660 tttacaagat atgattttta aaattaatac ggtccctaaa gctcagttta agtcagaagt 6720 gacaaaacac gtggatgtcg ataagtattt gcgctggctt gctggtattg tattcacctc 6780 gaactatgac gggtttgtcc acaactacgc attatacaga agcggggaaa ccggattatt 6840 tgaggtgatt ccttgggatt atgatgcgac ttggggcagg gatatccatg gagagcggat 6900 ggctgccgat tatgtaagaa ttcaaggatt taatacacta accgcccgga tattggatga 6960 atccgagttt cgcaagtcct acaagcgcct gttagaaaaa acgctccaat ctctttttac 7020 aatagaatat atggaaccga aaatcatggc gatgtatgaa cggattaggc cgtttgtcct 7080 catggacccg tataaaaaga atgatattga gcgttttgac cgtgagccgg atgtgatctg 7140 cgagtatatt aaaaaccgtt cacaatacct caaagatcat ttaagtattt tatgaatgcg 7200 tgaaaatggg tattcgcgga aaaagcgaca attaggctat tgaattagtt caacaaataa 7260 atgtgacacg tatatatgca gtatgtttat catctatgta taagtgacta ggaggaattt 7320 gaatgagcaa gaggagaatg aaatatcatt caaataatga aatatcgtat tataactttt 7380 tgcactcaat gaaagataaa attgttactg tatatcgtgg aggtccggaa tctaaaaaag 7440 gaaaattaac agctgtaaaa tcagattata tagctttaca agctgaaaaa aaaataattt 7500 attatcagtt ggagcatgtg aaaagtatta ctgaggatac caataatagc accacaacaa 7560 ttgagactga ggaaatgctc gatgctgatg attttcatag cttaatcgga catttaataa 7620 accaatcagt tcaatttaac caagggggtc cggaatctaa aaaaggaaga ttggtctggc 7680 tgggagatga ttacgctgcg ttaaacacaa atgaggatgg ggtagtgtat tttaatatcc 7740 atcacatcaa aagtataagt aaacacgagc ctgatttgaa aatagaagag cagacgccag 7800 ttggagtttt ggaagctgat gatttaagcg aggtttttaa gagtctgact cataaatggg 7860 tttcaattaa tcgtggaggt ccggaagcca ttgagggtat ccttgtagat aatgccgacg 7920 gccattatac tatagtgaaa aatcaagagg tgcttcgcat ctatcctttt cacataaaaa 7980 gcatcagctt aggtccaaaa gggtcgtaca aaaaagagga tcaaaaaaat gaacaaaacc 8040 aggaagacaa taatgataag gacagcaatt cgttcatttc ttcaaaatca tatagctcat 8100 caaaatcatc taaacgatca ctaaaatctt cagatgatca atcatccaaa tctggtcgtt 8160 cgtcacgttc aaaaagttct tcaaaatcat ctaaacgatc actaaaatct tcggattatc 8220 aatcatccaa atctggccgt tcgtcacgtt caaaaagttc ttcaaaatca tctaaacgat 8280 cattaaaatc ttcagattat caatcatcaa aatcatctaa acgatcacca agatcttcag 8340 attatcaatc atcaagatca ccaggctatt caagttcaat aaaaagttca ggaaaacaaa 8400 aggaagatta tagctatgaa acgattgtca gaacgataga ctatcactgg aaacgtaaat 8460 tttaatagat aatggaggag catcagataa agtgatgccc tttttcagtt aaaggaggag 8520 aatcgtgaaa ggtttgaatc aattccttaa cacagatgtt gaggttgtca tttcaggaga 8580 tacaaggttt gtcggcaccc tcatagatat cggacaggat atttttgtta tttttgatgg 8640 ctgcaattat ctttatattc ccttgttgca tcttcatcaa ataaacaagg cgaaaatagt 8700 gaccagtact gagaagccat ttttgatcaa tccggaagat ccaatgatag aggcagaaac 8760 tcaagctttt tcatatagaa atacattaaa caaggtcaaa ggccagttta ttgaagttta 8820 tgtaactggg ggtcgatcga tccatggata tgttacaaat gttttaaacg attatattgt 8880 atttttctca cccgtattta aaatactttt tatatctatg catcatttaa aatggtttac 8940 cccttattca actgaacaaa caccgtatac tcttgacaac tcacaattgc cggtcgtgcc 9000 ttccaaagtt cctcttgtgc gtaattttga ggagcagatc aaaaaaaata ttggtgaatt 9060 ggtcatattt gatatgggag aggtgccaga aaaagtcgga ctattaaagg gtgtctctaa 9120 taatatcatt gagcttatta acgcaagtgg agagccagtc atttggaagt taaatcatct 9180 aaagacaatg catcttccct agtgtataca aaactgccct cttgaaaagc agaaggcagt 9240 ttttcgtttc atactgtgct aaagaaataa ccaactgatc caaaaatata aacatgttaa 9300 cgtaaaaaga acagtcagcg gaatgatgat aatggtcgtt tttatatatt cgccccatga 9360 aatactttca tcatgctgtt ttaatatatg catccaaata agcgttgcta aggttcccat 9420 aggtaataat aatgaaccga tatcactgcc gataatattt gccaagtaga tgatttttgt 9480 tgttgaagga ttcagggtca tttcagttaa ggtaaaagta ctgatcatta acgctggatg 9540 gttgttaaag agattagaaa aaactgaagt agagatacct gatgcgaaag ttgcatgggc 9600 gaggcttcca gaaaccacag gttcaaaata actcacaagt aactctgtga atccaatatt 9660 atgcagacca taaattaaga catacatagt aaaagcgaat ataaaaatgt gccaaggcga 9720 tttatataac aagtctcttg gggaggtttt gaaataaatc catctccagc tcaacaggat 9780 aaaagatccg atgacagcga ctagaggaac agaaataccg gtatatgatg ctgcaaatag 9840 actcattctg acgagaaaaa caaatgcaag cacaaacaac atgatttttg tttgatttcg 9900 ttctggtaaa ggagctgatg gcgaatgaag aggatggtac cttctatgcc gcagagactg 9960 aaaatggccc ggtatatctg gcaggctttt gggaagacgt ttataaaaga acataaacag 10020 tagacaagtc ataaaaatga gtcccatcat actagggaca aacatcatgg cggtgtgaag 10080 atatagatcc attccaatga ttttgagaga aattaaatta acaatattac ttacgccaat 10140 cggtgcgcta gaggctgtgg ctattaaaac accgcttaat aaatatgggg ctttttgatg 10200 tttttttaaa cctaaatatt ttagtacaag caaaaggatt ggagttgtga tcaaaatgct 10260 cccatcatta ttaaggaaaa tggtcatgag aaagcagagc aaattggtta gccaaaaaag 10320 cttgatgcct gaacccttgg attgttggag cagttttgca gccacccaat aaaagaaacc 10380 aaagctttct agtgcaatgg ccataatcat agtggcaagg attgtaaccg atgcacccgt 10440 gacttttgtt ccgatttccc ctaagtctgc caatgacaca cttccgcaca ataaaaccat 10500 taaagcgcca aatgtggcgg ggatagcttc atttagtcct tttggtctcc agaaaataaa 10560 aatcattgtt acgaaaaaag cgagcaatgt gaatatgccg gtgaactcaa taatttactt 10620 cacctctcta tctttcattt ttaaaatcaa actaatgtcc tgcgcttact gatgtccttg 10680 ccaactattt gtactgtatg tatacgtata ctgatataaa gttgtactaa gcgattatat 10740 taaattaata aaaattccat aagaatccca aaagaaaaaa gagattgcaa gtattgttca 10800 tgtacctgca tcactctctt tagttcttgt ctgctgacaa tttgaaatat gaataaaatg 10860 ctttataagc ggattatgat tgtctttgcg gtaagcgata acccattctg cattaagctg 10920 tatttggtcc atttttcgat aagtaacatc caaattaaat aattttttgg ccgaggaagg 10980 aacaaatgtc ataccaattc cggcactgac taaaccaatc accatttgat attctgtggc 11040 ttcctggaca atgttgggtc tgaagcccgc ttgttcacag aactgaataa aatccatgta 11100 tagagtaggc catgcttctt tagcaacagt aataattggt tcatctctta aatcctcaat 11160 cgtaattgat tccttagaag tcaatgggtg ttgcttaggc aaagctaaaa cacaagggct 11220 gctttgggcg gtttcgatat gtaaagctgt atgctgtaag ggaggatgaa gtataccaat 11280 atcaatgttg ccctttagta gctcctcctg ctgcctagac gaggatattt cacgcagttc 11340 tattttcaca gatgggaatt ttttacgata ttcccggaca atcggcggca gaaattcata 11400 tgtagctgat ccgacaaaac cgattacgag aaggccttgc tcgccgcggg ccgtccgctg 11460 tgccagttca attccttgtc cgatttgcat caatgccatg cggcaatgat ttaaaaagat 11520 ttctcctgct gcggtaagct cgacaaatcg ttttgtcctt ttcagaagcg taactccgac 11580 ttcttcctcc agctgtttga tctgctggct gagaggaggc tgcgtcatgt tcagccgccg 11640 ggcagccttt ccgaaatgaa gctcttcggc tactgcgata aagtattgaa gatggcgaag 11700 ctccattcaa tatgcattcc tttccatagg ttaataattc gtattacata ttaatcataa 11760 ggcgaatcga tattggaggt caatttccaa agagtgtata gtgaaactta tcacaagata 11820 tttaaaattt tacgtttaaa atgcataata aggagtgagg gtgttgacaa aagcaacaaa 11880 agaacaaaaa tcccttgtga aaaacagagg ggcggagctt gttgttgatt gcttagtgga 11940 gcaaggtgtc acacatgtat ttggcattcc aggtgcaaaa attgatgcgg tatttgacgc 12000 tttacaagat aaaggacctg aaattatcgt tgcccggcac gaacaaaacg cagcattcat 12060 ggcccaagca gtcggccgtt taactggaaa accgggagtc gtgttagtca catcaggacc 12120 gggtgcctct aacttggcaa caggcctgct gacagcgaac actgaaggag accctgtcgt 12180 tgcgcttgct ggaaacgtga tccgtgcaga tcgtttaaaa cggacacatc aatctttgga 12240 taatgcggcg ctattccagc cgattacaaa atacagtgta gaagttcaag atgtaaaaaa 12300 tataccggaa gctgttacaa atgcatttag gatagcgtca gcagggcagg ctggggccgc 12360 ttttgtgagc tttccgcaag atgttgtgaa tgaagtcaca aatacgaaaa acgtgcgtgc 12420 tgttgcagcg ccaaaactcg gtcctgcagc agatgatgca atcagtgcgg ccatagcaaa 12480 aatccaaaca gcaaaacttc ctgtcgtttt ggtcggcatg aaaggcggaa gaccggaagc 12540 aattaaagcg gttcgcaagc ttttgaaaaa ggttcagctt ccatttgttg aaacatatca 12600 agctgccggt accctttcta gagatttaga ggatcaatat tttggccgta tcggtttgtt 12660 ccgcaaccag cctggcgatt tactgctaga gcaggcagat gttgttctga cgatcggcta 12720 tgacccgatt gaatatgatc cgaaattctg gaatatcaat ggagaccgga caattatcca 12780 tttagacgag attatcgctg acattgatca tgcttaccag cctgatcttg aattgatcgg 12840 tgacattccg tccacgatca atcatatcga acacgatgct gtgaaagtgg aatttgcaga 12900 gcgtgagcag aaaatccttt ctgatttaaa acaatatatg catgaaggtg agcaggtgcc 12960 tgcagattgg aaatcagaca gagcgcaccc tcttgaaatc gttaaagagt tgcgtaatgc 13020 agtcgatgat catgttacag taacttgcga tatcggttcg cacgccattt ggatgtcacg 13080 ttatttccgc agctacgagc cgttaacatt aatgatcagt aacggtatgc aaacactcgg 13140 cgttgcgctt ccttgggcaa tcggcgcttc attggtgaaa ccgggagaaa aagtggtttc 13200 tgtctctggt gacggcggtt tcttattctc agcaatggaa ttagagacag cagttcgact 13260 aaaagcacca attgtacaca ttgtatggaa cgacagcaca tatgacatgg ttgcattcca 13320 gcaattgaaa aaatataacc gtacatctgc ggtcgatttc ggaaatatcg atatcgtgaa 13380 atatgcggaa agcttcggag caactggctt gcgcgtagaa tcaccagacc agctggcaga 13440 tgttctgcgt caaggcatga acgctgaagg tcctgtcatc atcgatgtcc cggttgacta 13500 cagtgataac attaatttag caagtgacaa gcttccgaaa gaattcgggg aactcatgaa 13560 aacgaaagct ctctagcact ctgcgcatca cgacactgtt ttatgaacag cactaaataa 13620 aaggagtgaa gggaaatatg aaacgagaaa gcaacattca agtgctcagc cgtggtcaaa 13680 aagatcagcc tgtgagccag atttatcaag tatcaacaat gacttctcta ttagacggag 13740 tatatgacgg agattttgaa ctgtcagaga ttccgaaata tggagacttc ggtatcggaa 13800 cctttaacaa gcttgacgga gagctgattg ggtttgacgg cgaattttac cgtcttcgct 13860 cagacggaac cgcgacaccg gtccaaaatg gagaccgttc accgttctgt tcatttacgt 13920 tctttacacc ggacatgacg cacaaaattg atgcgaaaat gacacgcgaa gactttgaaa 13980 aagagatcaa cagcatgctg ccaagcagaa acttatttta tgcaattcgc attgacggat 14040 tgtttaaaaa ggtgcagaca agaacagtag aacttcaaga aaaaccttac gtgccaatgg 14100 ttgaagcggt caaaacacag ccgattttca acttcgacaa cgtgagagga acgattgtag 14160 gtttcttgac accagcttat gcaaacggaa tcgccgtttc tggctatcac ctgcacttca 14220 ttgacgaagg acgcaattca ggcggacacg tttttgacta tgtgcttgag gattgcacgg 14280 ttacgatttc tcaaaaaatg aacatgaatc tcagacttcc gaacacagcg gatttcttta 14340 atgcgaatct ggataaccct gattttgcga aagatatcga aacaactgaa ggaagccctg 14400 aataaaagaa aaaaagaaag ccccttttag cagggctttc tttttatttg gctcttttcc 14460 tgattttaga taaaataaca tcaaaacagt aaaggtgtgg tctgatgaaa atattggttt 14520 tggcagtgca tcctcatatg gagacctcag ttgttaataa ggcgtgggct gaggaattga 14580 gtaaacatga caatatcaca gtacgggatc tttataagga atacccggat gaagcgatag 14640 atgttgcgaa ggaacagcag ctgtgcgagg aatacgatcg gattgtcttt caattcccgc 14700 tatattggta cagctctccg ccgctcttga aaaaatggca ggatcttgtg ctgacttatg 14760 gctgggcttt tggttcagaa ggaaatgcct tgcatggcaa ggagctgatg ctggctgtat 14820 caacagggag cgaagcagaa aaatatcaag cgggcggagc aaatcattac tcgatcagtg 14880 agctattgaa accatttcag gccacgagta atctgatcgg catgaagtat ctgcctccat 14940 atgtgttcta tggcgtgaat tatgcagctg cagaggatat ttctcacagt gcaaaacggt 15000 tagccgaata catccagcag ccttttgttt aaaatacagc cctgtccaac atacggcagg 15060 gctgtatttg tttaaaaatc cggcagctca gacaggttat tttccttgat gccgtccggt 15120 tcacttcgca aaatgtcacg cccgtattta tggaagacat caacatgagc gagttttcct 15180 gattttgctt ctgacagcgc agtagggtag tcgagctc 15218 // |
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