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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   Z86002; SV 1; linear; genomic DNA; STD; PRO; 1027 BP.
XX
AC   Z86002;
XX
DT   18-FEB-1997 (Rel. 51, Created)
DT   18-APR-2005 (Rel. 83, Last updated, Version 2)
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DE   P.mirabilis dfrVI gene encoding dihydrofolate reductase.
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KW   dfrVI gene; dihydrofolate reductase.
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OS   Proteus mirabilis
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Proteus.
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RN   [1]
RP   1-1027
RX   PUBMED; 1941991.
RA   Wylie B.A., Koornhof H.J.;
RT   "Nucleotide sequence of dihydrofolate reductase type VI";
RL   J. Med. Microbiol. 35(4):214-218(1991).
XX
RN   [2]
RP   1-1027
RA   Adrian P.V.;
RT   ;
RL   Submitted (14-FEB-1997) to the EMBL/GenBank/DDBJ databases.
RL   Adrian P.V., South African Institute for Medical Research, Medical
RL   Microbiology, Cnr Hospital and deKorte Street, Johannesburg, Gauteng, South
RL   Africa, 2000
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FH   Key             Location/Qualifiers
FH
FT   source          1..1027
FT                   /organism="Proteus mirabilis"
FT                   /isolate="J120 (pUK672)"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:584"
FT   -35_signal      260..265
FT   -10_signal      284..289
FT   RBS             326..329
FT   misc_feature    316..320
FT                   /standard_name="core element"
FT                   /note="Gene cassette boundary"
FT   CDS             336..809
FT                   /transl_table=11
FT                   /gene="dfrVI"
FT                   /standard_name="DHFR"
FT                   /product="dihydrofolate reductase"
FT                   /function="trimethoprim resistance"
FT                   /EC_number="1.5.1.3"
FT                   /db_xref="GOA:P95524"
FT                   /db_xref="InterPro:IPR001796"
FT                   /db_xref="InterPro:IPR012259"
FT                   /db_xref="InterPro:IPR017925"
FT                   /db_xref="UniProtKB/Swiss-Prot:P95524"
FT                   /protein_id="CAB06660.1"
FT                   /translation="MKISLMAAVSENGVIGSGLDIPWHVQGEQLLFKAMTYNQWLLVGR
FT                   KTFDSMGKLPNRKYAVVTRSKIISNDPDVVYFASVESALAYLNNATAHIFVSGGGEIYK
FT                   ALIDQADVIHLSVIHKHISGDVFFPPVPQGFKQTFEQSFSSNIDYTYQIWAKG"
FT   repeat_region   830..861
FT                   /rpt_type=INVERTED
FT                   /note="The inverted repeat forms a stem and loop structure
FT                   which marks the boundaries of the gene cassette."
XX
SQ   Sequence 1027 BP; 299 A; 191 C; 219 G; 318 T; 0 other;
     cctgcagttg ccatgtttta cggcagtgaa gagatagcga gcgctgatgt ccggcggtgc        60
     ttttgccgtt acgcaccacc ccgtcagtag atgaacagga gggacagctg atagaaacag       120
     aagccactgg agcacctcaa aaacaccatc atacactaaa tcagtaagtt ggcagcatca       180
     ccctatttaa cttaattcaa atattttaga aaacttagtg atagtaatac cttaggatat       240
     ttgttaaaac tatatagagt agacaaatga gcgtttagtc ggcagaaata tgcgcgatga       300
     gcgcactatt aaattgttag ccctcaggag gaaaaatgaa aatatctctt atggcagctg       360
     tttccgagaa tggagtaatt ggctctggat tggatatacc ttggcatgta caaggcgagc       420
     agctcctatt caaagccatg acttacaatc aatggcttct agttggtcgt aaaaccttcg       480
     actcaatggg taaacttccg aatagaaaat atgcagtggt tactcgttct aaaattatct       540
     cgaatgaccc tgatgttgtg tatttcgcaa gtgttgaatc ggcattagct tacctaaaca       600
     atgcgacagc acatatcttt gtttctggtg gtggtgaaat atataaagct ttaatcgatc       660
     aagcagatgt tatccatctt tcagtgattc acaagcatat ctctggcgat gtgttttttc       720
     ctccagttcc acagggcttc aagcaaacat ttgagcaaag tttcagttca aatattgatt       780
     acacgtacca aatttgggca aagggctaac aatctgttta agagtgattc gcaacgcgtg       840
     gaatttttac tatgcgttgc gtttagtgtt taaggtggta tgcggaggct tcggtattgc       900
     gttgctcaca ccttaacagg gcgttatgtg tctcttggat ttaggtgaaa taaactatgt       960
     tgaatatcat taaatttatt cttatttcct taatgctttc agtgattttt atctatattg      1020
     ctctaga                                                                1027
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