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EBI DbfetchID Z69973; SV 1; linear; genomic DNA; STD; MAM; 1178 BP. XX AC Z69973; XX DT 01-APR-1996 (Rel. 47, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 4) XX DE C.familiaris cGMP-PDE gamma subunit gene XX KW cGMP phosphodiesterase gamma-subunit; cGMP-PDE gene. XX OS Canis lupus familiaris (dog) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis. XX RN [1] RP 1-1178 RA Kylma T., Paulin L., Hurwitz M.Y., Hurwitz R.L., Kommonen B.; RT "Sequence analysis of rod photoreceptor cGMP-phosphodiesterase alpha and RT gamma subunits: Exclusion of phosphodiesterase as cause for retinal RT degeneration in the Labrador Retriever dog"; RL Unpublished. XX RN [3] RP 1-1178 RA Paulin L.; RT ; RL Submitted (07-MAR-1996) to the EMBL/GenBank/DDBJ databases. RL Paulin L., University of Helsinki, Viikinkaari 9, Helsinki, Finland. XX RN [4] RP 1-1178 RX DOI; 10.1016/S0034-5288(97)90208-3 RX PUBMED; 9300552. RA Kylma T., Paulin L., Hurwitz M., Hurwitz R., Kommonen B.; RT "Cloning of the cDNA encoding rod photoreceptor cGMP-phosphodiesterase RT alpha and gamma subunits from the retinal degenerate Labrador retriever RT dog"; RL Res. Vet. Sci. 62(3):293-296(1997). XX RN [6] RP 1-1178 RX PUBMED; 8726673. RA Kommonen B., Kylma T., Cohen R.J., Penn J.S., Paulin L., Hurwitz M.Y., RA Hurwitz R.I.; RT "Elevation of cGMP with normal expression and activity of rod cGMP-PDE in RT photoreceptor degenerate labrador retrievers"; RL Ophthalmic Res. 28(1):19-28(1996). XX FH Key Location/Qualifiers FH FT source 1..1178 FT /organism="Canis lupus familiaris" FT /variety="labrador retriever" FT /mol_type="genomic DNA" FT /dev_stage="mature" FT /cell_type="rod cell" FT /tissue_type="retina" FT /db_xref="taxon:9615" FT 5'UTR <1..165 FT CDS join(166..311,600..640,987..1063) FT /gene="PDEG" FT /product="cGMP-phosphodiesterase gamma subunit" FT /db_xref="GOA:P54827" FT /db_xref="InterPro:IPR006952" FT /db_xref="UniProtKB/Swiss-Prot:P54827" FT /protein_id="CAA93815.1" FT /translation="MNLEPPKAEIRSATRVIGGPVTPRKGPPKFKQRQTRQFKSKPPKK FT GVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII" FT exon <1..311 FT /number=1 FT /experiment="experimental evidence, no additional details FT recorded" FT intron 312..599 FT /number=1 FT exon 600..640 FT /number=2 FT /experiment="experimental evidence, no additional details FT recorded" FT intron 641..986 FT /number=2 FT exon 987..>1178 FT /number=3 FT /experiment="experimental evidence, no additional details FT recorded" XX SQ Sequence 1178 BP; 189 A; 424 C; 364 G; 201 T; 0 other; cccgtgaccc tgagacctgc ccagggcttg gacttcctct gttcagctgg ttgagacctg 60 caaggggggc agccgcaggg ggggctgact ggtgtgcccc cagcccacag cgtgagggga 120 gtctagaagc cagacgtcgc cgtggggttc tctgccaacc tggccatgaa cctggagcca 180 ccgaaggccg agatccggtc ggccaccagg gtgattgggg ggcccgtcac tcccagaaaa 240 gggcccccca aatttaagca gcggcaaacc aggcagttca agagcaagcc ccccaagaaa 300 ggcgtccaag ggtaagcaga gctggcggag gggcccagcc gcaggctacc caggaattgg 360 ggggggcggc caccctttcc tggctgaggt cggtcccacc atcctactag gctggggtgg 420 tgcccctcat tcctcagcat ggaggtggga gggctcgggg ccccctggca ctgtccccct 480 gaggaccaca ctcactgccc cttagtgact gggccacagc ccccgcacca gcctgtgtcc 540 ccgcatgcac ccccactccc ctcctcctgg ccactggccc tgaccactct gtcctgcagg 600 tttggggacg acatccctgg aatggaaggc ctggggacag gtatgacggc atctagggtc 660 ttcccagatc ccccaactct cccgcgggcc gtgggctggg gcctgtgctc cctgtgctgt 720 ctccagccgg agcttaccta gggcatcgcc ccaagcctgt ctgtcctctg ccccaacccc 780 gagctttagc ctcaccgagg ggctgctcct ttcagtgggt tcgccgggta cttggaggtg 840 ccggagagca ccgaggggcc ctcgctgtcc tctcacctcc ctggcgtgct gtacccgtac 900 gcttccctcg acaccctggg aagaggacct ctgggcgtgg acaacagggc cacgaccccc 960 ctgatgccct gtcccttctc ctgcagacat cacggtcatc tgcccttggg aggccttcaa 1020 ccacctggag ctgcacgagc tggcccagta cggcatcatc tagcgccaga gcctgaccca 1080 gaggcttggg gccagggtcc ctgccgccca ctccgctccc tgctccgggt gcctgcgagg 1140 aggccggccc ccccccgcgg tgtccagacg gcccagtg 1178 // |
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