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EBI DbfetchID Z69785; SV 1; linear; mRNA; STD; ROD; 2032 BP. XX AC Z69785; XX DT 19-MAR-1996 (Rel. 47, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 9) XX DE C.porcellus mRNA for 11-beta-hydroxylase XX KW 11-beta-hydroxylase; CYP11B1 gene. XX OS Cavia porcellus (domestic guinea pig) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricognathi; Caviidae; OC Cavia. XX RN [1] RP 1-2028 RX DOI; 10.1006/bbrc.1996.0591 RX PUBMED; 8619851. RA Bulow H.E., Mobius K., Bahr V., Bernhardt R.; RT "Molecular cloning and functional expression of the cytochrome P450 RT 11B-hydroxylase of the guinea pig"; RL Biochem. Biophys. Res. Commun. 221(2):304-312(1996). XX RN [2] RC Revised by [3] RA Buelow H.E.; RT ; RL Submitted (26-FEB-1996) to the EMBL/GenBank/DDBJ databases. RL Buelow H. E., Max-Delbrueck-Center for Molecular Medicine, Cellbiology, RL Robert-Roessle-Strasse 10, Berlin, Germany, 13122 XX RN [3] RP 1-2032 RA Buelow H.E.; RT ; RL Submitted (13-AUG-1997) to the EMBL/GenBank/DDBJ databases. RL Buelow H. E., Max-Delbrueck-Center for Molecular Medicine, Cellbiology, RL Robert-Roessle-Strasse 10, Berlin, Germany, 13122 XX FH Key Location/Qualifiers FH FT source 1..2032 FT /organism="Cavia porcellus" FT /strain="Duncan Hartley" FT /mol_type="mRNA" FT /sex="male" FT /dev_stage="adult, low sodium /high potassium diet" FT /clone_lib="lamda ZAP II" FT /clone="pHBL 5 /pHBL 19" FT /tissue_type="adrenal gland" FT /db_xref="taxon:10141" FT mRNA 1..2014 FT /gene="CYP11B1" FT 5'UTR 1..5 FT CDS 6..1508 FT /gene="CYP11B1" FT /product="11-beta-hydroxylase" FT /db_xref="GOA:Q64408" FT /db_xref="HSSP:1SCC" FT /db_xref="InterPro:IPR002401" FT /db_xref="UniProtKB/Swiss-Prot:Q64408" FT /protein_id="CAA93633.1" FT /translation="MAFRLKSDVRLAGSWLCLRGARALGTRAVTASKASVLPFEVIPQH FT QGNKRQRVLQFWKEQNHDDLHLEMHQTFQELGPIFRCDVGSTRIVAVMLPEDCARLHQA FT ESPYPHRMHLEPWMAYREHRRQNLGVFLLNGPEWLSNRRWLNPNVLSPKAVQNLLPMVD FT TVARDFSEALKQKVLQSAQGSLTMDMQPDIHKYTVEVSNFALFGERLGLFGCNPSSQSL FT KFIHALEAVFKTTTQLMFLPRSLSRWMRSQAWKEHFEAWDYISEYAENRIQKKYEELAR FT GCSQYNSIVANLMLQGNLPLRAMKANIMDLVAGSVDTTALPLMMTLFELARNPTVQQAL FT RQESMATEPNIYENPQRLRMELPLLWAAIKETLRMYPVGLFLERFLTSPLVLQNYHIPA FT GTLVHLNLYSMGRNPEVFLSPEHYNPQRWLENKETYKHLAFGFGVRQCIGRRLAEVEML FT LFLHHVLKSFCVETAFQEDVKFAYRFVMMPTSAPLLTFRPVS" FT sig_peptide 6..77 FT mat_peptide 78..1505 FT /product="11-beta-hydroxylase" FT /function="11-beta-hydroxylation, 18-hydroxylation, FT 19-hydroxylation" FT /EC_number="1.14.15.4" FT 3'UTR 1509..2014 FT polyA_signal 1994..2000 FT polyA_site 2014 XX SQ Sequence 2032 BP; 541 A; 491 C; 489 G; 511 T; 0 other; tgaaaatggc atttaggttg aagtcagatg tgcggctggc aggttcttgg ctgtgcctgc 60 gtggggccag ggcactgggc accagagcag tcacggcctc caaagcctca gtgctgccct 120 ttgaagtcat accccaacac cagggcaaca agaggcagag ggtgctgcag ttctggaagg 180 agcagaacca tgatgacttg cacctggaga tgcaccagac cttccaggag ctggggccga 240 ttttcaggtg tgatgtggga agtacacgga tagtcgctgt gatgctgcca gaggactgtg 300 cgaggctgca ccaggcagag agcccctatc cccatcgcat gcacctggag ccctggatgg 360 cctacagaga gcaccgacgg cagaaccttg gcgtgttttt gctgaatggg cctgaatggc 420 tctccaaccg acggtggctg aacccaaatg tgctgtcccc aaaggcagtg caaaacctcc 480 tccccatggt agacacagtg gcaagagact tctcagaggc tctgaagcag aaggtacttc 540 agagtgccca ggggagcctg accatggaca tgcagcccga catccataag tatactgtgg 600 aagtcagcaa ttttgcacta tttggtgaaa gactgggcct ttttggctgt aaccccagct 660 ctcaaagcct gaaattcatc catgccctgg aggccgtatt taaaacgacc acacagttaa 720 tgtttctgcc aagaagtcta tcccgctgga tgagaagtca agcatggaag gagcactttg 780 aggcctggga ctacatttct gagtatgctg aaaatcgcat ccagaagaaa tatgaggagc 840 ttgctcgagg ttgctctcag tacaacagca ttgtggcaaa tctgatgctg caggggaatt 900 taccactacg tgccatgaaa gcaaacatta tggacctcgt ggcagggagt gtggacacga 960 cagccttacc attgatgatg acactctttg agttggccag gaatcctacc gtgcagcagg 1020 ccctgcggca ggagagcatg gctactgaac ccaatattta tgagaatccc cagagactca 1080 gaatggagct cccccttctg tgggcagcca tcaaggaaac cctgaggatg taccctgttg 1140 gtctttttct ggagagattc ctgacctcac ccttggtgct tcagaactac cacatcccag 1200 cagggacttt ggtgcattta aatctgtact ccatgggccg aaaccctgag gtgttcctga 1260 gtccagagca ttacaacccc cagcggtggc tggagaacaa ggagacctat aagcatctgg 1320 cctttggatt tggggttcgc cagtgtattg gacggcgcct agcagaagtg gagatgctgc 1380 tgtttctcca tcatgtgctg aagtccttct gtgtggagac agcattccaa gaggatgtga 1440 agttcgccta ccgcttcgtt atgatgccca cctctgcacc cctcctcact ttcaggcctg 1500 tcagctaatg tcaccttcct gctgagtctc cccaccatgc caccattgtc tgtccctatg 1560 actctagacc attccgccac ttctgcaaag gcactgcttc ctagctacac tgctgctcag 1620 tggaccttct gatgaaacag tccctgcaaa agcaataaga actgtgggag caataaaact 1680 caaaatgtgt aatagtcatt atacaaaaca gaagaaaaga aagtgctcta aatgatataa 1740 ctgcatataa atttaagtgt gtaagataaa caatgatatt actgagtttt gttggatcat 1800 tgaacagaac tgtttgcagt ctcactgttt gaatgttcac tttacatgct ttaatcttgt 1860 aacttgaacg aacaaatatt tctaagatga caatatgtaa ttcattaact agtgattttc 1920 tactgtttat ttttttctga aattctgtat aacttgtacc ctttttctgc tttttttccc 1980 ctttttttcc ttaaattaaa aaaaagaaac agtcaaaaaa aaaaaaaaaa aa 2032 // |
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