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EBI DbfetchID Z48951; SV 1; linear; genomic DNA; STD; FUN; 17660 BP. XX AC Z48951; U00094; XX DT 04-APR-1995 (Rel. 43, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 2) XX DE S.cerevisiae chromosome XVI cosmid 9723. XX KW CDE1; CDE2; CDE3; centromere; citrate synthase; delta element; KW electron transport flavoprotein; HAL1; halotolerance; isocitrate lyase; KW LTR; transfer RNA-Gly; transfer RNA-Phe. XX OS Saccharomyces cerevisiae (baker's yeast) OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. XX RN [1] RP 1-17660 RA Pearson D., Bowman S.; RT ; RL Unpublished. XX RN [2] RP 1-17660 RA Barrell B., Rajandream M.A., Walsh S.V.; RT ; RL Submitted (03-APR-1995) to the EMBL/GenBank/DDBJ databases. RL Saccharomyces cerevisiae chromosome XVI sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR RFAM; RF00005; tRNA. DR UniProtKB/Swiss-Prot; Q6B0V7; YPR02_YEAST. XX CC Notes: CC CC All CDS over 100 codons have been analysed. CDS that are CC completely overlapped and those that are overlapped by more than CC 50% CC of their length by a larger CDS have been omitted from this CC analysis. CC Details of the omitted CDS are available on request. CC The more significant matches with motifs in the PROSITE database CC are CC also included but some of these may be fortuitous. CC The length in codons and the calculated codon adaptation index CC (CAI) CC is given for each CDS. CC CC Cosmid 9723 lies beetween cosmid 8132 and cosmid 9531. XX FH Key Location/Qualifiers FH FT source 1..17660 FT /organism="Saccharomyces cerevisiae" FT /chromosome="XVI" FT /map="XVIR" FT /strain="AB972" FT /mol_type="genomic DNA" FT /clone="cosmid 9723" FT /db_xref="taxon:4932" FT misc_feature 1..99 FT /note="overlap with sequence from cosmid 8132, EMBL entry FT SC8132X, accession no. Z48483" FT misc_feature 139..146 FT /note="cen16 CDE1 motif" FT misc_feature 147..230 FT /note="cen16 CDE2 motif" FT misc_feature 231..256 FT /note="cen16 CDE3 motif" FT CDS 559..2019 FT /product="unknown" FT /note="YP9723.01, putative citrate synthase gene, len: 486, FT CAI: 0.12; PS00480 Citrate synthase signature" FT /db_xref="GOA:P43635" FT /db_xref="InterPro:IPR002020" FT /db_xref="InterPro:IPR016141" FT /db_xref="InterPro:IPR016142" FT /db_xref="InterPro:IPR019810" FT /db_xref="SGD:S000006205" FT /db_xref="UniProtKB/Swiss-Prot:P43635" FT /protein_id="CAA88779.1" FT /translation="MVQRLLPGAHICRRSFNSSAIIKSSALTLKEALENVIPKKRDAVK FT KLKACYGSTFVGPITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNT FT GIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPM FT TQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTLEDSLNLIASLPLLTGRIYSNITNE FT GHPLGQYSEEVDWCTNICSLLGMTNGTNSSNTCNLTSQQSLDFINLMRLYTGIHVDHEG FT GNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLIEMNSNISSIAREQ FT EIKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAMLEFAQKRPIEFENDKNVLLMQKLAE FT IAPKVLLEHGKSKNPFPNVDSASGILFYHYGIRELLFFTVIFGCSRAMGPLTQLVWDRI FT LGLPIERPKSLNLEGLEALTKASNVNKL" FT misc_feature 1630..1668 FT /note="PS00480 Citrate synthase signature" FT CDS 2567..4117 FT /product="unknown" FT /note="YP9723.02, unknown, len: 516, CAI: 0.13, similar to FT B43936, orf 3' of CTSA - Bacillus sp. (54.3% identity in FT 105 aa overlap)" FT /db_xref="GOA:Q12428" FT /db_xref="InterPro:IPR005656" FT /db_xref="InterPro:IPR012705" FT /db_xref="SGD:S000006206" FT /db_xref="UniProtKB/Swiss-Prot:Q12428" FT /protein_id="CAA88780.1" FT /translation="MFLAKNLKNNKIKVCLPKKKFAALSTASIQTNERPNPDKVLKDIA FT KYVHETPLKSSLALDTARLCFLDTLGCGLAALKFKQAQNIIKPIVPGTIVPSGTKILGT FT SYVMDPVKGAFAIGTLIRWLDYNDCWLAAEWGHPSDNLGGILAVADHLSRLNKATHGKN FT GKQFLVKDVLEAMIKAHEIQGIIALENSFNKVGLDHVVLVKVATAGVVSKMLGLSQEQT FT IEALSQAFVDGQSLRTYRHAPNTGSRKSWAAGDAVSRAVNLAYLVKNANVGTIPSVLTA FT RTWGFYDVLFKGKPFSFQQRSKYDSYVMENVLFKISFPAEFHAQTAVEAAVKAYRILAK FT QGKTFKDIKSIRIRTQEAAMRIIDKSGPLYNYADRDHCIQYMIAVPLITGNLTATDYSD FT EVARNPEIDNLRSKMYCIEDTHLTQNYHDPDKRSIGNALLIELNDGTQLDEIFVEYPVG FT HKFRREEGIPLLMNKFQRHLREHFVESPDKVDLIMKVSSKTNFLNMQIDKYMDLFTEG" FT tRNA complement(4380..4471) FT /note="tRNA-Phe gene, anticodon gaa, potential intron FT between positions 4434 4416, length = 92" FT LTR 4663..4994 FT /note="solo delta element, 91% identity to a delta element FT consensus sequence" FT LTR 4947..5266 FT /note="solo delta element, 40.7% identity to a delta FT element consensus sequence" FT CDS complement(5686..7950) FT /product="unknown" FT /note="YP9723.03c, unknown, len: 754, CAI: 0.10, some FT similarity to S34800 Nodulin (Clone GMN70) - Soybean (24.1% FT identity in 436 aa overlap) and to sulphate permeases eg FT YB8H_YEAST P38359, YBR294W (22.2% identity in 514 aa FT overlap)" FT /db_xref="GOA:P53394" FT /db_xref="InterPro:IPR002645" FT /db_xref="InterPro:IPR011547" FT /db_xref="InterPro:IPR018045" FT /db_xref="SGD:S000006207" FT /db_xref="UniProtKB/Swiss-Prot:P53394" FT /protein_id="CAA88781.1" FT /translation="MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSN FT RGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYY FT LPCFSWLPEYTFNKLWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVY FT GILGSVPQMIVGPESAISLVVGQAVESITLHKENVSLIDISTVITFVSGTILLFSGISR FT FGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDY FT APAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYHKSAIFFPDILLVVIVTILISMKFNL FT KHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGT FT TYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITL FT ITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTT FT IFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVE FT GTEEIEGCMIVRIPEPLTFTNSEDLKQRLDRIERYGSSKIHPGRKSLRSKDSIKYVIFD FT LGGMTSIDSSAAQVLEEIITSYKRRNVFIYLVNVSINDKVRRRLFKAGVAASVERAQAN FT NNENNTSNTFSDAGETYSPYFDSIDAALYEIEKMKIKGNNVPNNDSESFMSNTLFNSSL FT V" FT CDS complement(8189..9223) FT /product="unknown" FT /note="YP9723.04c, len: 344, CAI: 0.15, putative electron FT transport flavoprotein, similar to ETFA_HUMAN P13804 (45.3% FT identity in 342 aa overlap); presence of splice branch FT consenus sequence, tactaac, upstream at position 9322, may FT indicate splicing at the 5' end of the gene" FT /db_xref="GOA:Q12480" FT /db_xref="InterPro:IPR001308" FT /db_xref="InterPro:IPR014729" FT /db_xref="InterPro:IPR014730" FT /db_xref="InterPro:IPR014731" FT /db_xref="InterPro:IPR018206" FT /db_xref="SGD:S000006208" FT /db_xref="UniProtKB/Swiss-Prot:Q12480" FT /protein_id="CAA88782.1" FT /translation="MFKSLAAVLPRASKAKFLQKNYASTLAFIESSKDGSVSRSSLSLL FT AAAQKLSNPITAVITGSKAEKTAEALKSSYSCSNLEKLVIFEDSKLDTCLPEQLTPLLV FT KLLKGGDYSHFVVSNSSVGKSVLPRVGALLDVQPVCEVTVIKDPKTFIRPIYAGNIIST FT IECQAEKKLLIIRASAFPPIAEGSMDSVTIEKRTDIPPCDLNVTWVKTILTKSERPELT FT SAQNVVTGGRALKDKETFEKLLSPLADVLHAAIGATRASVDNGLCDNSLQIGQTGKVVA FT PNLYIAIGVSGAVQHLAGMKDSKVIVAINNDPDAPIFNVADYGLQGDLYKIVPELTEKL FT GKYK" FT CDS complement(9969..10853) FT /gene="HAL1" FT /product="Hal1p" FT /note="YP9723.05c, HAL1 gene, len: 294, CAI: 0.12, FT HAL1_YEAST Q01766 halotolerance protein" FT /db_xref="GOA:Q01766" FT /db_xref="SGD:S000006209" FT /db_xref="UniProtKB/Swiss-Prot:Q01766" FT /protein_id="CAA88783.1" FT /translation="MHFKDLGLHDYTLKNLMYENNCCKFYDAVDENNISYVLKFVPSDV FT TSEGDTFPFVDRFQVKEGVFLVYSSNDFGKEGTDYFTYTGSGGNEVHISGTSSEAGIKP FT QFIETCHPKHLKRGTKEQEDINSSTSKKSAVINNFSGEKTPNPRPQSSNISERETYVGI FT LNVKCKNKNSSKIRSEKLVSSVIETKHTPGLASILSKEGTTYPNNADGKHISIVNPSSK FT IYHSSHKQIVKTPIPKSGLSPIERCPFNGQNIKCYSPRPLDHESPQRDFNNNFQLRILK FT SSVLQRRQSTQNS" FT CDS complement(11451..13178) FT /product="unknown" FT /note="YP9723.06c, putative isocitrate lyase, len: 575, FT CAI: 0.16, similar to ACEA_YEAST P28240 isocitrate lyase FT (EC 4.1.3.1) (41.6% identity in 541 aa overlap)" FT /db_xref="GOA:Q12031" FT /db_xref="InterPro:IPR000918" FT /db_xref="InterPro:IPR006254" FT /db_xref="InterPro:IPR015813" FT /db_xref="InterPro:IPR018523" FT /db_xref="SGD:S000006210" FT /db_xref="UniProtKB/Swiss-Prot:Q12031" FT /protein_id="CAA88784.1" FT /translation="MITMINNKTFNRKTTGTLKKLVLSSDKSLRRSFNGASSTKDFVFS FT ESSKVEEWWESARFKNISRPYSATDVVKHRGSLPANTSIYPSSYQARKLFNLLEENFKN FT GTPLHTLGVIDPVQMSQLARCRNIKVAYISGWACSSTLVGSTNEVSPDFGDYPYDTVPN FT QVERIFKAQQLHDRKAFLEASIKGSTPVDYLKPIIADADMGHGGPTTVMKVAKLFAEKG FT AAGIHLEDQMVGGKRCGHLSGAVLVPTATHLMRLISTRFQWDIMGTENLVIARTDSCNG FT KLLSSSSDPRDHEFIRGIIRDNVVPWSEKLIEMEDKKIPNSAIADMEKEWYHENELFTF FT EEALEKQFTASEFESYKEKKEDLMVNKLGRAYLSLREMKLLAQEVTPLKKIIFDWDAPR FT TKEGYYMFNGCIEAAIRRSLVFAPYSDMIWLETKTPDLEQARSFSRKIHKQLPATKLVY FT NLSPSFNWSAHGFDDKALKSFVWDLAKEGFTLQLVSLAGLHSDGVSFWELANSFQSDGM FT KAYVEKVQKREKETNCDIMTHQLWSGAEYVDSLMKVVQNGASSQTLSTSGESFTETQF" FT CDS complement(13518..15560) FT /product="unknown" FT /note="YP9723.07c, unknown, len: 680, CAI: 0.14" FT /db_xref="GOA:Q12188" FT /db_xref="InterPro:IPR006910" FT /db_xref="SGD:S000006211" FT /db_xref="UniProtKB/Swiss-Prot:Q12188" FT /protein_id="CAA88785.1" FT /translation="MAPLSLNFKDDKKYKGLTTVWLLSALGNSIVKESNNYYSNKSNST FT GNISSSTVKKKDIVNISIPKTCDEIQNFENDFSLRYISNLLYGVTICYNKKTEYVLNDL FT NHLLVQLQKNDVYAFKAKNKSTRINGLNSNNSIIGNKNNNYTWEECVFFDDDPLYDITK FT VPALEFLNTTLQDNVSFIEEAKSIRRQDYINELSNSNRFELHGDMTNSDAQSNLGSNVR FT NSFPLDEIPVDVDFNLDLDDIVSHQGTPLGSHSSSQKDGNDFKFNYQGDELVLNFENDN FT ENNSNGGEDTSVENEGPVANLKDYELGLEAQASEEENDLQQKLNTRMQRGHRADVGGQF FT SKVQFDAKTSYPNEVLKFNHGNYSHLMEKNRIRKLTGQNFLTSNISSLVRSCGEEEFFS FT TNWLSIFNDFSNIKTSEWDLYPQGFSSVERGRKRAHSLVSTQSSSSTRSHEYGRKSFRN FT NKNDNYSSDMENDNLLLNLEQINEDLEDGHYIEENSQGNILDFNLNLPPSSFGRSHTRN FT STRSSGFNEDIVGALRRRVGPSEQNFAEEDDSSNSCFSDGSQQNLQQDKTNFQDVILDY FT QTKKFYDYIKERSIVVGRTTRSNPPFKRKMLLVDIIPSRMGEAQTGANFDDVERGVSRQ FT IAASAFLSLLNLATKGMVKLNEYPVADAVTKDLKLRREDEIIVYA" FT LTR complement(16027..16355) FT /note="solo delta element, 46.3% identity to a delta FT element consensus sequence" FT tRNA 16451..16521 FT /note="tRNA-Gly gene, anticodon gcc, len: 71" FT CDS 17200..>17660 FT /product="unknown" FT /note="YP9723.08, putative transcription factor, FT incomplete, len: >153, CAI: 0.13, similar to A41116, FT transcription factor AMT1, (40.2% identity in 127 aa FT overlap) and ACE1_YEAST P15315 (38.9% identity in 149 aa FT overlap)" FT /db_xref="GOA:Q12753" FT /db_xref="InterPro:IPR001083" FT /db_xref="InterPro:IPR018373" FT /db_xref="UniProtKB/Swiss-Prot:Q12753" FT /protein_id="CAA88786.1" FT /translation="MVLINGIKYACERCIRGHRVTTCNHTDQPLMMIKPKGRPSTTCDY FT CKQLRKNKNANPEGVCTCGRLEKKKLAQKAKEEARAKAKEKQRKQCTCGTDEVCKYHAQ FT KRHLRKSPSSSQKKGRSISRSQPMFERVLSSTSLDSNMLSGHGALSDTS" XX SQ Sequence 17660 BP; 5517 A; 3307 C; 3281 G; 5555 T; 0 other; caaagtgtct ctatagttaa tataagctta tgcaaaggtt gaagccgtta tgttgtcgta 60 attctaaatt acaggttata ttaaagagat tatcttgact gatataaaat ttcttatcat 120 ggtagtgatc acaaatagat cacatgatat attttttatt tttaattttt tttaattata 180 aaaataattt ttttctttaa attaaacaaa aataaaaaat tgttttttgt tggttaagat 240 ttccgaaaat agaaatatta ttcagttgaa agacaaaaaa acataaatat ttctatgagc 300 aaacaatttg aacagaaaaa taaaattggg gaagtgacac accatggtag cggttctaaa 360 gcgaaatcgg caaagcggct aaatagcagt tttgatgact tactccacac tgaaaatgga 420 tgaccttaaa taggagataa agctttttca tccctatgta tttaagatga ctggcttgtc 480 aagcattcta atcataaaaa aaagatcgta tttgatcaag aatttataca tagacgccgc 540 taaataattg aatacaaaat ggtacaaagg cttctaccgg gcgcacatat atgcagaagg 600 tccttcaatt cgtctgcaat tataaagtct tctgcattga ctctcaagga agcattagaa 660 aacgtgatac ctaagaaaag agatgctgtg aagaaattga aggcctgtta tggcagcacg 720 tttgtcggac cgattaccat ttcatcagtt ctaggtggga tgagaggtaa tcagtcaatg 780 ttttggcaag gaacatcatt agatcccgaa catggcatta aatttcaagg tttaacgatt 840 gaagaatgtc aaaatagatt acctaataca ggtattgatg gcgataattt cctgccagaa 900 tcaatgttat ggctgttgat gacaggtggt gtgccaactt tccagcaagc tgcttctttc 960 aggaaagaat tggctattcg tggaaggaaa ttgccacatt atacagagaa agttttgtca 1020 agtttaccca aagatatgca ccctatgacc caacttgcaa ttggtttagc atcaatgaac 1080 aaaggatccc tctttgctac aaactaccaa aagggcctca taggaaagat ggaattttgg 1140 aaagatactc ttgaagattc gctaaattta attgcttcac tcccgctgct gactgggaga 1200 atttattcga acattacaaa tgagggacac ccattaggtc aatatagtga ggaggtggat 1260 tggtgtacaa acatatgttc cctgctcggc atgacaaatg gaacgaactc ttctaataca 1320 tgcaacctta cttcccagca atccctggac ttcataaact tgatgcggtt atataccggt 1380 atacatgtag accatgaagg tggtaatgtt tctgctcaca ccacccactt ggttggaagt 1440 gcgttgagtg acccgtatct cagctattca tctggaataa tgggattagc gggtcctttg 1500 catgggttag cagcacaaga agtagtaagg tttctcatag agatgaactc taatatttcc 1560 agcattgcac gagaacaaga aatcaaagat tatctttgga aaattttgaa ttcaaaccgt 1620 gtgatccccg gttatgggca cgcagttttg cgtaaaccgg atcctcgatt tacagcaatg 1680 cttgaatttg cgcaaaagag gcctattgaa tttgagaacg acaagaacgt tttgttgatg 1740 caaaaattgg cagaaatagc gcctaaggtt ttgttggaac acggaaagag taagaatcca 1800 tttcccaatg ttgactctgc atcggggatt ttgttttatc attatggaat cagggaatta 1860 ttattcttta ccgtcatttt tgggtgttca agggccatgg gacccttgac acaacttgtt 1920 tgggatcgca ttctaggttt accaattgaa aggcccaaga gtttgaactt ggagggtctg 1980 gaagcactta ccaaagcaag caatgttaac aagttgtaac gcagttccaa tttacaagaa 2040 tgcttcgttt gctattacaa tattgaaata taaataaaat tccatacagc atgtctaatc 2100 atagctaatt tatacatatt catcatgaaa acatataggg gaaaatatgg tcggttaaca 2160 cacctatcaa aaaattattc agcaattcca atctcgttag taaaatatat tcttattttt 2220 tttttttttc tctgattgta ttatttctgg agttttgact tattttttta ccacatcgcg 2280 cttttcgtcc ccaatctctc tgatatatga tgctgtctat aggtagccac ttccccgatg 2340 tcggacctcg ggccgtttac aaactttatt gagatgacct tatttctcca cattctagtc 2400 attcaacttt taccctcata tgtttacctt cactaatgtg aaagcatgac caaagaaagt 2460 gtataaggta tataaatctg ccataatgta tgtataactt attaggactt tctcaaatag 2520 tattttggta ttttctactg ttctctgatg atcgagagca aacagaatgt ttttagccaa 2580 aaatctaaaa aataataaaa tcaaggtatg cttgcctaaa aagaaatttg ctgcgctgag 2640 tacagcgtct atacaaacta atgaaagacc aaatccagat aaggttttga aggacatcgc 2700 gaaatatgtc catgaaaccc cattaaaatc atctttggct ctagatacag cacgactctg 2760 tttccttgat actctaggct gtggcttggc ggctttgaaa tttaagcagg ctcaaaatat 2820 tattaaacca attgtgccag gaacaatagt tcccagtgga acaaaaatat tgggcacatc 2880 ttacgttatg gatccagtga agggagcttt tgccattggt actctaatac gttggttaga 2940 ttacaatgac tgctggttag ctgccgagtg ggggcaccca tcagataacc ttgggggaat 3000 tttagctgtc gcggatcact tgtccagatt aaacaaggct acccacggaa agaatggaaa 3060 acagtttctt gttaaagacg tattagaggc aatgattaaa gcgcatgaaa tccaaggtat 3120 tatagcgctc gaaaattctt tcaataaagt aggtttagat catgtggtac tcgtgaaagt 3180 agcaacggct ggtgttgtct cgaagatgct gggcctgagc caggaacaaa ctattgaagc 3240 attgtcacaa gcatttgtag acggtcaatc actgcgtact taccgtcatg ccccaaatac 3300 tggatctaga aagtcgtggg cggcgggaga tgcagtttcg agggctgtaa acttggctta 3360 tttagtcaaa aatgctaatg ttggcacgat accttcagta ttaacagcta gaacctgggg 3420 attttatgac gttttattta agggtaaacc tttttcattc caacaaagat caaaatatga 3480 ttcctacgtc atggaaaacg ttctgttcaa gatatcattt cctgccgaat tccatgcgca 3540 aactgctgta gaagctgctg taaaagcata taggattctt gccaaacaag ggaaaacttt 3600 taaagatatt aaatcgatca gaattagaac tcaagaggcg gcaatgagga ttatagataa 3660 atccggtcct ctgtataatt atgccgatag ggatcattgt atccagtaca tgatcgcggt 3720 tccgctgatt actggtaatc tcacagctac tgattattcg gatgaggtcg caagaaatcc 3780 tgagatcgat aacttgagat cgaaaatgta ctgtatcgaa gatactcatc tcactcaaaa 3840 ctatcacgat cctgataaaa ggtcgatagg aaacgctctt ctcatagagc tgaacgatgg 3900 gacgcagttg gatgaaattt ttgtagagta ccctgttggt cacaaattta gacgagagga 3960 aggaatacca ttactaatga ataaatttca aaggcatctg cgcgaacatt ttgtagagag 4020 ccctgataaa gtcgacctta taatgaaggt aagttcaaaa acaaactttt tgaatatgca 4080 aatcgacaaa tacatggatt tgtttactga gggatgaatg gttggctctt taagagcgaa 4140 cggcatggta cctacttcaa tttttaaaga caaaaggcgc cgtttcgata aacaagaaat 4200 cactttcaaa acataattaa accaaagaac atgcggtttt ctaattatgc tggcttaatt 4260 ttactggtat ttatctacat aataataact attaaaaaat taaataattg gctctattta 4320 tttttctttc ttcaacttgc aagagttcgt caattcatgg aaaaatacaa aaatagaaat 4380 gcgaattctg tggatcgaac acaggacctc cagataactt gaccgaagtt ttttcttcag 4440 tctggcgctc tcccaactga gctaaatccg ctcaatttct atgctctaac caccttagct 4500 aaaaactcaa tacaggatta gttgataaat gggtgttatc aactcaatcc acagtgttgg 4560 aatcagagtc agttatcatc tttgggctag tattattgta agtgttggaa taaaaattct 4620 aaaatatcat ccatttagta gtgttcatat tactaatata tctgttggaa taaaaatcca 4680 ctatcgtcta tcaactaata gttatattat caatatatta tcatatacgg tgttaagatg 4740 atgacataag ttatgagaag ctgtcatcga ggttagagga agctgaagtg caaggattga 4800 taatgtaata ggataatgaa acatataaaa cggaatgagg aatattcgta atattagtat 4860 gtagaaatat agattccatt ttgaggattc ctatatcctc gaggagaact tctagtatat 4920 tctgtatacc taatattata gccttcatca acaatggaat cccaacaatt atctcaacat 4980 tcacccattt ctcaatatca tcacgtgcgg tctaagaaga tgatatgaag attgagaata 5040 gtcatcaggt gtaatggaag ctaattgcaa ggattggtaa tttagtagga tgatgaatga 5100 cagtcacata agatgaaaag gaaaacaata atgccattat atcgagaata tcgatctctt 5160 cgtggattct tctcatagag aaattctagt ataatatata tacgaaatat tatggccttt 5220 aacaacaata aaattccaac aattatcaac taattcgaac atctcttgac aatatacatt 5280 attaattttt acatttcgac tttctttgaa ttagggactg tctctcaatt catctctttc 5340 tcatacagaa tatcacttat cctatataac ttatataaga ttagaatcta actagagcga 5400 ggagagcgga aactcggatc aaaagtgatt gtttaagtgt ttgtgcgttt gtgcggctca 5460 ttaagacaat aaggttttgc ttttgtattc aattttgtgg gttttataac gtataaatgc 5520 gcttcttgaa agcttgttaa cgattttatc gtaaagaaat aaataaacta aagaattgag 5580 gagacaatac tgttttgata aataagcccc aaaaatatta tagggccgca aggaataaat 5640 ttcataatgc gcatatgccc agactcctct gtttctttcg aagttttaca ctagacttga 5700 attaaataaa gtattggaca taaaactctc cgaatcattg ttcgggacgt tgttcccttt 5760 aattttcatt ttctcaattt cataaagagc cgcatcaatg ctatcgaagt acggagaata 5820 tgtctctcct gcatcactaa atgtgttgct agtattattt tcgttgttat ttgcttgcgc 5880 tctttccaca ctagcagcta cacctgcttt gaataatcgc cttcttactt tgtcatttat 5940 agatacattg acaaggtaaa taaagacatt gcgcctcttg taactagtga taatttcctc 6000 cagcacttgg gcggctgaag aatctattga ggtcatccca cctaaatcga aaatgacata 6060 ttttatggaa tccttcgagc gaagtgattt ccttccagga tgtatcttag acgaaccgta 6120 cctctctatt ctgtcaagtc tctgttttaa atcttcgctg tttgtaaatg tgagaggctc 6180 aggtattcta acaatcatgc atccctcgat ttcttctgtg ccctcaacat ccagagagtt 6240 ccttttcatg ttcatcatgt agtcgtcaag attcgtaaag ttcgacgttc ccgctaccct 6300 agccagaatt tggattcttg actttgctga atgctttata atatttataa ttgaatagac 6360 acatccgatg catattcctg cttcgattga gtaaaatatt gtagtgcaga aggtaacagc 6420 aaaaacaaat agttcactaa agccaccaca tcgcaaatgg aactttatgt cgcctggcac 6480 ttcctctaat aaactaattc cgatgatggt tgttatgacg gataaaacac aattaggaat 6540 ataatgtacg aattgaagaa gtaaattcat tgtgattagg gtgatgacac ccataaacac 6600 tcccgacatt acgctttgtg ctcctgatag ggcgttgatc ttggatcttc catatccgcc 6660 gaatgcggga agagcaccga ataatgagat gacaatattc atgaatccta aagctactag 6720 ttctctatta gaggaaacgg taagattgta agttgttcca agagatttcg acgcggtcgt 6780 agattcaaaa aaacccaaca ttgccactat tagagatgca ctaaaaagat ctggtattag 6840 cttacgtcta ggacgagtta aagggttttt caattcatca aaattgtcca tgctaaagtc 6900 gccaatgata gaaataccat atctgtgttt taaattaaat ttcatggaaa taagaatagt 6960 aacaattacc accaataata tatctggaaa aaatattgcg ctcttgtgat atttcattaa 7020 tttcctcttt agtagacgcg ttaaaaagag gacaatcaag caacatccgc tgaatattgc 7080 cgttggtata tggtattgtg ctggtgcata atcaatgagg aaaagtattt tctcgaaagg 7140 ggtatggtag tgttgaggca agcttactaa aaatttgtct agctttaatt cagaaatcaa 7200 agagttgatt atcataacca gtcctactga acttatgaaa cctcgtagaa gtgccttgct 7260 aagaacattt ccaaggaaac caaatctgga aataccagaa aaaagtagga tagtgccact 7320 aacaaatgtt attactgttg aaatatcaat tagagaaaca ttttctttat gtagtgttat 7380 agattcgact gcttgtccca cgaccaagga aattgcactt tcgggcccaa ctatcatctg 7440 aggaacagaa cctaaaatac catagacaaa tgggctaata gccaaagaat atagtccgca 7500 taaaggtggg acatgtgcaa ttgaagttgt gtacgatagc gcaagtggta tctgaaatga 7560 cgctactgag atacctgcga ttacgtcgcc ccacagttta ttgaaagtgt actcaggaag 7620 ccatgaaaag cagggcaggt aataaggtaa agtttcaaac actgtattct catcaacgct 7680 atcattattg ttcgtattac ttgtattact tgtattattt gtattatttg tattattggt 7740 gcatcctgat cttgagttgt tgggtggggg taccccagta gttgaattag atgctgcaat 7800 ataggtcctg cctcgattgg atgaatcctt atcataatca aaattgtccg agaaagtgtc 7860 acgctggtcg actgatcttt tgaatcttgg tggagcggta gaggaatatg acatccttcc 7920 acgccccaat aacgaattat ttgatgtcat cctataattg tttccgtaag ttcttggaaa 7980 tcactaggaa gtttgtggag ttattgttct cctcatattc tcccatctgg aagaactcta 8040 ttattccttt gccatttctc gtagtctttt atatttagtc cgctttacac cgaaaaggtc 8100 atttttaaaa aggcaagaga actaggaaaa gtaaaacgtg cccccttcaa agcgaagaga 8160 tgaatatatt tagaagttaa gaatttattt atttatattt accaagtttt tcagttagtt 8220 cagggactat tttgtaaaga tccccttgca acccatagtc agcgacatta aatatagggg 8280 catcaggatc attgttaatg gcaacgataa ctttcgaatc cttcattccc gctaaatgct 8340 gaactgcacc agaaacgcca atggctatat acaaatttgg tgcgactacc ttaccagtct 8400 gaccgatttg tagagaatta tcacatagtc cattatcaac agaagctctt gtggcaccta 8460 tagcagcgtg caaaacatct gctagcggcg ataatagctt ctcaaatgtc tccttatcct 8520 tgagtgccct tccaccagtt accacgttct gtgcagaagt aagttcaggc ctttcactct 8580 tggtaagaat agttttaacc caggtaacat ttaagtcaca aggaggaata tcagttctct 8640 tctcaatggt aacagaatcc atactaccct ctgcaattgg tggaaaagct gatgccctaa 8700 taatcaacag ttttttttct gcctggcatt ctattgtaga aataatgtta cctgcataaa 8760 ttggccttat aaaggtctta ggatctttga ttacagtaac ctcacaaaca ggttggacgt 8820 ccaagagcgc acccacccga ggtaaaacac tttttccaac agaggagttt gagacaacaa 8880 aatgtgaata gtcgccgcct tttaatagtt tcactaataa cggagttagt tgttcgggaa 8940 gacaggtatc taattttgaa tcttcaaata tgacaagctt ttctaaattg ctgcatgaat 9000 atgaagattt tagcgcctca gcagtttttt cagctttgct acctgtgatt acagctgtga 9060 tagggttaga caacttttgt gcagcagcca ataaactcaa tgatgacctt gaaacagagc 9120 catcttttga gctttcaatg aaagctaaag tggaggcgta atttttctgg aggaactttg 9180 ccttgctagc tctaggcaag acagcagcca atgatttaaa catagaaatt aacaattagc 9240 tgctttaccg ttaatggtag taaattatat cactagattt tgtttgttga ttattttaat 9300 tgtttttaat ttttagttag tagattttcg ttcgaggccc taaaaatgta ccgaaaagtc 9360 ataataaacg ggcggagtca catcgtaaga gtaacatata caatatgcga gcagactttg 9420 tccattaagc caagtaacaa caaaagaacc aaaaaaagga aagtatctcg tctctgttga 9480 gtaattctta tatcttgcaa gatttaattc tcactactaa tacggaactc aatcaaagtg 9540 gcttaatccc aagacatgca ttgaatacgg tatcattggc tgttgacagt ttaagaaaag 9600 tagttgtcac gttcctgagg ttactgggga caagggaaag tagatactcg tcttacgaaa 9660 ttggatatag ttactctcta atgctcaatc catgtaaagc atgaatcatc tcaacagaaa 9720 aatctgggag agcatatttg caacaaaaga atccaaatat cagtatataa ttatataagt 9780 gagctaagaa gtgaacaaaa gaaaaggaag aggggaaaaa ttttggctgg acttgtagaa 9840 cgatagaacg aaagagtcca agggggaagt aataaagtta ttgaacgaaa caacaaaaat 9900 tcgatggaga tattaacaaa tgcatagcag cgcagctaac cgacccgaag ctagtaccaa 9960 cgaatttttc aactattctg tgttgattgt ctcctttgca acaccgagct cttcagtatt 10020 ctcagctgaa agttattatt gaaatcacgt tggggacttt catgatctag tggtcttggt 10080 gagtagcatt taatattttg accattgaaa gggcatctct caattggaga aaggccactc 10140 ttagggatag gcgttttaac aatctgttta tgggatgaat gatatatttt tgaggatgga 10200 ttcacgatac tgatatgttt cccgtccgca ttattcggat atgtagtgcc ttctttcgat 10260 aaaatagatg ccaatcctgg cgtatgcttt gtttcgatga cggagcttac caatttttca 10320 cttcgtattt tcgatgagtt cttattttta catttgacgt tcaatattcc gacatacgtc 10380 tctctttctg aaatgttgga actctgtggc cttggatttg gtgttttttc acccgaaaaa 10440 ttgttgataa ctgcactttt ctttgaggta ctactattta tatcttcctg ctcttttgtt 10500 ccccgcttaa gatgttttgg atggcaagtt tcaataaact gcggttttat tcctgcttct 10560 gaagaggtgc ccgagatgtg aacctcattt ccaccactac cagtataagt aaagtagtcc 10620 gtaccttctt ttccaaagtc atttgaggaa tataccaaaa aaacaccttc ctttacttga 10680 aagcgatcca cgaatgggaa agtatcccct tccgaagtca catctgaggg aacaaatttt 10740 aaaacatatg agatgttgtt ttcatccacg gcatcataaa atttacagca attattctca 10800 tacatcaagt ttttgagagt gtagtcatgc aatcctaaat ctttgaaatg catctgatct 10860 atttgtttct gtatttctct tttcttgagt tatataaacg gaatgattag tagtttggca 10920 gaatttatag caagtattaa atagttgaat acctcaatat tctccataat aaacgccata 10980 tcgtacataa aggctaaaac aagaatgcct gataccgttc tgctttttgt tttatctttc 11040 cctatatttt ctttcccttt tgatgcttta cgtaattttt cccggcatat gtgagcttcc 11100 taatagactc tatttttatt tttccctttc aaagtgcgag agaaatacac acaaccagcc 11160 tacgcttatt ttcacccata ccgtcatacg ccatatgata tataatgtga aacaaacgcg 11220 gggaagagcg cgacacgaca gcttagcagg ggcattccac gcaacacctg aaactttaag 11280 taaaactgtt tctgcgagga tatcttggca aaacaaacac taactttcga actaaatata 11340 gtgatcgtgg tcataaatta ataaaaagag gataaataga gataaaagag atatgtgact 11400 aagttgctgg caatatgtat tatttatact tttatcttct tgaagcgtat tcaaaattgc 11460 gtttcggtaa agctctcacc agatgtactt aaagtttggg atgaagcacc gttttggaca 11520 actttcatta aggaatcaac atattctgca ccagaccata gctggtgtgt catgatatca 11580 caattagtct ccttttcccg tttttgcact ttttcgacgt atgctttcat tccgtcactt 11640 tggaagctat tggctaattc ccagaatgat actccatctg aatgcagacc ggcaagggaa 11700 accagttgca acgtgaagcc ttcttttgcc aagtcccata cgaaggattt taatgcctta 11760 tcatcaaagc cgtgagcgct ccaattgaaa ctaggagata agttatatac tagcttggta 11820 gctggaagtt gtttatgaat ttttcttgaa aatgagcgtg cctgctccag gtcaggagtt 11880 ttcgtttcca gccaaatcat atcagaatat ggggcaaaca ccaaagatct tctaatagct 11940 gcttcaatac aaccgttaaa catgtaatat ccctctttgg tcctcggagc atcccagtca 12000 aatataattt tctttagtgg tgtcacttct tgagctaaaa gtttcatttc tcttaagctt 12060 aggtatgctc tacccagctt gtttaccata aggtcttcct tcttttcttt atagctttca 12120 aactcgcttg ccgtaaactg cttttctaag gcctcttcaa atgtaaacag ctcattttca 12180 tggtaccatt ctttttccat gtcagcaatg gcggagttgg gaattttttt gtcctccatc 12240 tcaatcaatt tttcgctcca aggcaccacg ttatctctta ttatacccct aatgaattcg 12300 tggtctctcg gatcactgct tgaactcaac agcttaccat tacaggaatc tgttcttgca 12360 ataaccaaat tttctgtccc catgatatcc cattgaaacc tggtggaaat caatctcata 12420 agatgtgttg ctgtgggcac caaaacagcc ccacttagat ggccacacct tttgcctccc 12480 accatctgat cttcaagatg aataccagca gcccctttct ccgcaaacaa cttagcaact 12540 ttcattacag tcgttgggcc accgtgaccc atgtctgcgt ccgcgataat tggttttaaa 12600 taatcaacag gagtagaacc tttgatggag gcctccaaga aagcctttcg atcgtgcaat 12660 tgctgcgcct tgaatattct ctccacttga ttcggcacag tatcgtatgg ataatcgcca 12720 aaatccggcg atacttcatt tgtagatcca actaatgtgg aagaacaagc ccaaccagat 12780 atgtaagcaa ctttgatatt tctgcaacgg gccaactgac tcatttgtac aggatcgata 12840 actcccaacg tgtgaagtgg agtaccattc ttgaaattct cttctagtaa gttgaacagc 12900 tttcgagctt gataagatga aggataaatt gaagtattag caggaaggct gccccgatgc 12960 tttacaacat ccgtagctga gtatggacga ctgatattct taaatctggc tgattcccac 13020 cattcttcta ctttacttga ttccgagaac acgaagtctt tagtactgct tgccccgttg 13080 aaagatcttc gcagtgactt gtctgatgac aaaaccagct tcttcagtgt tcccgtagtt 13140 tttctattga aagttttgtt gttaatcatt gtaatcatcg gcgaaatact agaaaagtcg 13200 aaatcgatat tattatcggc gctgtagctt ctttaggcca ctagtacttt tataagctct 13260 tcaaccgcaa caaaagttaa gaaataagag agttattctt aagcccattt tttacattat 13320 atagtgtacg tatgatatcg ctagcatgat gttagtgttt cggcgcttct aattgaagag 13380 catatccttt tcttctccaa tgcactttta tttctttccc cgcaagcata ttcggcccgg 13440 atctcggact tggatcatta acctgaggac agcggctagt aaccgctgtc gctcatatgg 13500 aaggagaaaa taaaaattca ggcatataca attatttcgt cctctcttct cagtttaaga 13560 tctttagtta ccgcatctgc aacaggatat tcgttcaact tgaccatccc tttcgtagcc 13620 aaattcagta aggataggaa ggcactggcg gctatctgtc tgctgacacc tctttctaca 13680 tcatcaaagt tagctcccgt ttgagcttcg cccatgcggc ttgggatgat gtcaaccaac 13740 agcatctttc tcttgaaagg cggattggag cgcgttgttc ttccgacaac aattgatctt 13800 tctttgatgt aatcgtagaa ttttttagtt tgataatcca gaatgacgtc ttgaaaattt 13860 gttttgtcct gctgcaaatt ttgctgagag ccatcagaaa aacaactgtt gctggaatcg 13920 tcttcctcgg caaaattctg ttcagatggc ccgactctcc ttctgagagc accaactata 13980 tcttcattga aaccactaga cctggttgag tttctggtat gacttcttcc aaaacttgaa 14040 ggaggtagat tcaaattaaa atctaggatg ttaccttgag agttttcttc aatatagtgc 14100 ccatcttcca aatcctcatt aatttgttca aggtttaaaa gtaaattatc attttccata 14160 tcggaagaat aattatcgtt cttattattg cgaaaacttt tcctaccata ttcgtgactt 14220 ctggtactac ttgagctttg ggttgatact aaagaatgtg ctctttttct ccctctttca 14280 actgaactaa aaccttgggg atataagtcc cattcgctag tctttatatt ggaaaagtcg 14340 ttaaatatac ttaaccaatt tgttgaaaaa aattcttcct caccacatga ccttaccaaa 14400 ctacttatgt tagaggtgag aaaattttgg ccggttagtt ttctaatcct gtttttttcc 14460 attaagtgac tgtaatttcc atggttgaat ttgagaactt catttggata actcgttttg 14520 gcatcaaatt gtaccttaga aaattgccca cctacatcgg cgcgatgtcc tctttgcatt 14580 ctggtgttaa gtttctgttg aagatcgttt tcttcttcag aagcctgcgc ttctaacccc 14640 aattcgtagt ctttgagatt ggctaccggc ccttcatttt caactgatgt atcttctcct 14700 ccattactgt tattttcatt atcgttctca aaattcaaca ccaattcatc tccttgataa 14760 ttaaacttga aatcgtttcc atccttctgt gaacttgagt gagagcctaa aggtgtcccc 14820 tgatggctca ctatatcatc taagtccagg ttaaagtcca catcaacggg aatttcatcc 14880 agcggaaaag aatttctaac gttagatcct agattacttt gcgcgtctga gttagtcatg 14940 tccccatgaa gctcgaacct gttagaatta cttaactcat tgatgtagtc ttgtctcctt 15000 attgatttag cttcctcaat aaaagataca ttatcttgga gagtagtgtt aagaaactcc 15060 agtgcgggaa ctttagtaat atcatataag ggatcgtcat cgaaaaaaac gcattcttcc 15120 caggtgtaat tattgttttt gtttcctata atactgttat tactattcaa tccattaatc 15180 ctcgtagact tatttttggc cttaaaagcg tatacatcat ttttttgtaa ctgcacaagc 15240 aggtgattta ggtcattcaa cacatactcg gtttttttat tatagcaaat tgtcactcca 15300 tataaaagat tagaaatgta tctaagagaa aaatcatttt cgaaattttg aatttcatca 15360 catgtttttg gtatggaaat atttacgatg tcttttttct taacggtgga tgaagatatg 15420 tttccagtgg agttgctttt gtttgaataa taattgttac tttcctttac aatggaattt 15480 cccaacgcag aaagcaacca cactgttgtg aggcccttat atttcttgtc atctttaaag 15540 ttcaacgaaa gaggtgccat tgcagaatat ttgtaatatt aatctatata tagcaaatgc 15600 tttagagttg ctgaggctaa aaagaaatta tagaacaact ataaaatatt aagtccggat 15660 acactgcttc ctttatacca tgcccttccc tttatagtgt aaaaacgcgt aatcttaatc 15720 aatctgatat attggtttgc cgccgaagtc aagttctcct gctaaaacga gacaaaaaga 15780 acacgtgaaa gaagaaagaa aaacgttacg ataaaataag ttttatacct actttcatat 15840 ctaccaaagg aacacaatga attgccgtat gttattcttg aagtaagagt caagtattat 15900 ttatggacta gtattcacgt tactagtaca ttatcacatg cggtgtaaga agatgatata 15960 aaaattgagg gacagtaatc aaattcaacg gaagtcaaaa aggaaggatt ggtaatgtat 16020 aatatcgaaa aatgtgcgaa atagttgata attgttggag ttttatagtt gttaaaggct 16080 ataatattac gtatttagaa tatactagaa tttctctatg agaagaaccc acgaagagat 16140 cgatattctc gatataatgg cattattgtt atccttttca tcttatgtga ctgtcattca 16200 tcatcctact aaattatcaa tccttgcaat tagcttctat tacacctgat gactgttttt 16260 caatctttat gtgatctttt tacacccaat gtgataaagt actagtaaca tgaatactac 16320 taaacagatg atactttaga gttttcattc caacactcaa ttgtaaaaat aagacaatat 16380 tatgattttt tggctgtata accacatcta tttagtagca gggtgacatg ttactcccac 16440 acaatacttc gcgcaagtgg tttagtggta aaatccaacg ttgccatcgt tgggcccccg 16500 gttcgattcc gggcttgcgc aatttttccc cctcgccctg aagggcgtaa cgttaacgct 16560 tccggtaatt tgcgaataat ttttcttccc atttcccctt tcttttccct ttaacatgtg 16620 gagcatagca ggctctttac ttttttacgc attcagacag tcgggaggtc aattggtggt 16680 gccggttgtg ggaaagaggt aattttattt cctttattgg acatgatttc aatagtcaca 16740 ttggggcagg aaaaagaaaa gggagaaaaa aattcagtaa agaaaaaaaa taagaaaaag 16800 agaaaagaaa caagagaggg ctacagattt ctaaatatcc ttttgctgca cattttttat 16860 ttacctgcta attggtctta gtaatacaga gtcgtgcatt tccactttat aagaaaaaaa 16920 aaagggataa cagcaccagc acttgattga aaactagaaa gttcacgttt tataagtcct 16980 ttccgttctc tttatcagtt ataataaaag agccaagaca aaacgtggca gggaagcttt 17040 tccaaggaaa agagggttgt aatattaaac aaaaaccgta atcaagcaaa ataagacccc 17100 gtggtttttt atcataggaa aagagttctc tgttgtcact ctaccatatt tgacaagaaa 17160 aaggaaacaa aagtatagaa aaaaaaaacc taaaaaataa tggtcttgat aaatggcata 17220 aagtatgcct gtgagaggtg cataagaggc catagagtaa caacatgcaa tcatacagat 17280 caaccgctta tgatgatcaa acccaaaggt agaccttcca ctacatgcga ctattgtaaa 17340 caacttcgaa aaaacaagaa tgcaaatcct gaaggtgttt gcacgtgtgg ccggctagag 17400 aagaaaaaac tggcacagaa agccaaagaa gaagcaagag ctaaagccaa agaaaaacaa 17460 agaaaacagt gtacctgcgg gactgatgag gtttgcaaat atcatgctca aaagagacat 17520 ctaagaaagt ccccttcaag ttctcaaaag aaaggaagat ccatttctcg ttctcaacca 17580 atgtttgaaa gggtattgtc ttctacttca cttgacagca atatgttatc cggccacgga 17640 gcactatcag atacctctag 17660 // |
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