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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   Z48233; SV 1; linear; genomic DNA; STD; PRO; 1308 BP.
XX
AC   Z48233;
XX
DT   30-JUN-1995 (Rel. 44, Created)
DT   18-APR-2005 (Rel. 83, Last updated, Version 6)
XX
DE   S.epidermidis thyF and dfrC genes.
XX
KW   dfrC gene; dihydrofolate reductase; thyF gene; thymidylate synthase.
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OS   Staphylococcus epidermidis
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
XX
RN   [1]
RX   PUBMED; 7768789.
RA   Dale G.E., Broger C., Hartman P.G., Langen H., Page M.G., Then R.L.,
RA   Stueber D.;
RT   "Characterization of the gene for the chromosomal dihydrofolate reductase
RT   (DHFR) of Staphylococcus epidermidis ATCC 14990: the origin of the
RT   trimethoprim-resistant S1 DHFR from Staphylococcus aureus?";
RL   J. Bacteriol. 177(11):2965-2970(1995).
XX
RN   [2]
RP   1-1308
RA   Stueber D.;
RT   ;
RL   Submitted (10-FEB-1995) to the EMBL/GenBank/DDBJ databases.
RL   Dietrich Stueber Dr., PRPG, F.Hoffmann-La Roche Ltd, Grenzacherstrasse 124,
RL   Basel, 4002, Switzerland
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1308
FT                   /organism="Staphylococcus epidermidis"
FT                   /strain="ATCC14990"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:1282"
FT   CDS             <1..295
FT                   /codon_start=2
FT                   /transl_table=11
FT                   /gene="thyF"
FT                   /product="thymidylate synthase"
FT                   /EC_number="2.1.1.45"
FT                   /db_xref="GOA:P0C0M4"
FT                   /db_xref="HSSP:4TMS"
FT                   /db_xref="InterPro:IPR000398"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0C0M4"
FT                   /protein_id="CAA88268.1"
FT                   /translation="SADIFLGVPFNIASYALLTHLVAKECGLEVGEFIHTFGDAHIYSN
FT                   HMDAIHTQLSRDSYLPPQLKINTDKSIFDINYEDLELINYESHPAIKAPIAV"
FT   RBS             324..331
FT                   /note="putative"
FT   CDS             337..822
FT                   /transl_table=11
FT                   /gene="dfrC"
FT                   /product="dihydrofolate reductase"
FT                   /EC_number="1.5.1.3"
FT                   /db_xref="GOA:P0C0P0"
FT                   /db_xref="HSSP:1DHI"
FT                   /db_xref="InterPro:IPR017925"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0C0P0"
FT                   /protein_id="CAA88269.1"
FT                   /translation="MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHVKQLTTGNTLVMGR
FT                   KTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLFEAMID
FT                   QVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKGK"
FT   RBS             821..826
FT                   /note="putative"
FT   CDS             832..>1308
FT                   /transl_table=11
FT                   /gene="ORF3"
FT                   /product="unknown"
FT                   /db_xref="HSSP:1MGP"
FT                   /db_xref="InterPro:IPR003797"
FT                   /db_xref="UniProtKB/TrEMBL:Q54140"
FT                   /protein_id="CAA88270.1"
FT                   /translation="MAKQIIVTDSTSDLSHEYLKQHNIHVIPLSLTIDGKSYTDQVDIS
FT                   SSEYIDHIENDADVKTSQPPIGRFIETYEQLAQDDVEIISIHLSSGLSGTYNTAVQASH
FT                   MVDGNITVIDSKSISFGLGYQIKQIVELISQGTSTEEIVKEMTQLRDNLQLFVVI"
XX
SQ   Sequence 1308 BP; 469 A; 210 C; 231 G; 398 T; 0 other;
     aagtgctgat atatttttag gtgttccttt caatattgca agttatgctt tactgacaca        60
     tcttgttgca aaagaatgtg gacttgaggt gggtgaattc attcatacat ttggagatgc       120
     acatatttat tccaatcata tggatgcaat acatacacaa ttatcaagag atagttatct       180
     accacctcaa ttaaaaatta atacagataa atcaattttt gatattaatt atgaagattt       240
     agaattgata aattatgaat cacaccctgc tattaaagca cctattgcgg tataaaaaga       300
     tgcattaata tttcgcatac agaaaggagg tataccatga cattatcaat aattgtcgct       360
     cacgataaac aaagagtcat tgggtaccaa aatcaattac cttggcactt accaaatgat       420
     ttaaagcatg ttaaacaact gaccactggg aatacacttg taatgggacg gaaaactttt       480
     aattctatag ggaaaccatt gccaaataga cgtaacgtcg tactcactaa ccaagcttca       540
     tttcaccatg aaggggtaga tgttataaac tctcttgatg aaattaaaga gttatctggt       600
     catgttttta tatttggagg acaaacgtta ttcgaggcaa tgattgacca ggtagatgat       660
     atgtatatca cagtaataga tggaaagttt caaggagaca cattctttcc accatacaca       720
     ttcgaaaact gggaagtcga atcttcagta gaaggtcaac tagatgaaaa aaatactata       780
     ccgcatacat tcttacattt agtgcgtaga aaagggaaat aggaggcaat tatggctaaa       840
     caaattatcg tcacagattc aacctctgat ttatcacatg aatatttaaa acaacataac       900
     attcatgtta taccattaag cctgacaatc gacgggaaat cttacactga tcaagttgat       960
     atctcttcaa gtgagtatat cgatcatatt gaaaatgatg cagacgtcaa aacaagtcaa      1020
     ccacctattg gtcgatttat tgaaacatat gagcaattag ctcaagatga cgttgaaatt      1080
     ataagtattc atctttcgtc aggcttaagt ggtacttata atactgctgt tcaagcgagc      1140
     catatggtag atggcaatat cacagtgatt gattctaaat ctatttcgtt tgggttaggt      1200
     tatcaaatta agcaaattgt tgaattaata agtcaaggta catcaacaga agaaatagtg      1260
     aaggaaatga cacagttacg tgataacttg caactgtttg tggttatc                   1308
//
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