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EBI DbfetchID Z37996; SV 1; linear; genomic DNA; STD; FUN; 17421 BP. XX AC Z37996; Z47047; XX DT 06-OCT-1994 (Rel. 41, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 2) XX DE S.cerevisiae chromosome IX cosmid 9167. XX KW DNA primase small chain; pri1; regulatory protein; KW small nuclear ribonuclearprotein; sts1. XX OS Saccharomyces cerevisiae (baker's yeast) OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. XX RN [1] RP 1-17421 RA Pearson D., Bowman S.; RT ; RL Unpublished. XX RN [2] RP 1-17421 RA Barrell B., Rajandream M.A.; RT ; RL Submitted (29-AUG-1994) to the EMBL/GenBank/DDBJ databases. RL Saccharomyces cerevisiae chromosome IX sequencing project, Sanger Centre, RL Hinxton Hall Hinxton, Cambridge CB10 1RQ by Bart Barrell and Marie-Adele RL Rajandream. E-mail: barrell@sanger.ac.uk XX DR TRANSFAC; T02309; T02309. DR UniProtKB/Swiss-Prot; Q3E7Z3; YI018_YEAST. XX CC Notes: CC CC All CDS over 100 codons have been analysed. CDS that are CC completely overlapped and those that are overlapped by more than CC 50% CC of their length by a larger CDS have been omitted from this CC analysis. CC Details of the omitted CDS are available on request. The more CC significant CC matches with motifs in the PROSITE database are also included but CC some CC of these may be fortuitous. The length in codons/amino acids is CC given CC for each CDS as is the calculated CAI (Codon Adaptation Index). CC CC Cosmid 9167 lies between cosmids 9687 and 9168. XX FH Key Location/Qualifiers FH FT source 1..17421 FT /organism="Saccharomyces cerevisiae" FT /strain="AB972" FT /mol_type="genomic DNA" FT /clone="cosmid 9167" FT /db_xref="taxon:4932" FT CDS <1..2236 FT /codon_start=2 FT /note="incomplete orf, len: 744, CAI: 0.14" FT /db_xref="GOA:P40566" FT /db_xref="InterPro:IPR001547" FT /db_xref="InterPro:IPR013781" FT /db_xref="InterPro:IPR017853" FT /db_xref="InterPro:IPR018087" FT /db_xref="UniProtKB/Swiss-Prot:P40566" FT /protein_id="CAA86077.1" FT /translation="IQLRGVNLDPSVKIPAKPFLSTHAPIENDTFFEDADKVSFINHPL FT VLDDIEQHIIRLKSLGYNTIRLPFTWESLEHAGPGQYDFDYMDYIVEVLTRINSVQQGM FT YIYLDPHQDVWSRFSGGSGAPLWTLYCAGFQPANFLATDAAILHNYYIDPKTGREVGKD FT EESYPKMVWPTNYFKLACQTMFTLFFGGKQYAPKCTINGENIQDYLQGRFNDAIMTLCA FT RIKEKAPELFESNCIIGLESMNEPNCGYIGETNLDVIPKERNLKLGKTPTAFQSFMLGE FT GIECTIDQYKRTFFGFSKGKPCTINPKGKKAWLSAEERDAIDAKYNWERNPEWKPDTCI FT WKLHGVWEIQNGKRPVLLKPNYFSQPDATVFINNHFVDYYTGIYNKFREFDQELFIIIQ FT PPVMKPPPNLQNSKILDNRTICACHFYDGMTLMYKTWNKRIGIDTYGLVNKKYSNPAFA FT VVLGENNIRKCIRKQLSEMQKDAKSMLGKKVPVFFTEIGIPFDMDDKKAYITNDYSSQT FT AALDALGFALEGSNLSYTLWCYCSINSHIWGDNWNNEDFSIWSPDDKPLYHDTRAKTPT FT PEPSPASTVASVSTSTSKSGSSQPPSFIKPDNHLDLDSPSCTLKSDLSGFRALDAIMRP FT FPIQIHGRFEFAEFNLCNKSYLLKLVGKTTPEQITVPTYIFIPRHHFTPSRLSIRSSSG FT HYTYNTDYQVLEWFHEPGHQFIEICAKSKSRPNTPGSDTSNDLPAECVIS" FT misc_feature 713..742 FT /note="Glycosyl hydrolases family 5 signature" FT CDS complement(2315..3544) FT /gene="pri1" FT /product="DNA primase small chain" FT /note="len: 409, CAI: 0.17, pri1 gene, PRI1_YEAST P10363" FT /db_xref="GOA:P10363" FT /db_xref="InterPro:IPR002755" FT /db_xref="InterPro:IPR014052" FT /db_xref="SGD:S000001447" FT /db_xref="UniProtKB/Swiss-Prot:P10363" FT /protein_id="CAA86078.1" FT /translation="MTNSVKTNGPSSSDMEYYYKSLYPFKHIFNWLNHSPKPSRDMINR FT EFAMAFRSGAYKRYNSFNSVQDFKAQIEKANPDRFEIGAIYNKPPRERDTLLKSELKAL FT EKELVFDIDMDDYDAFRTCCSGAQVCSKCWKFISLAMKITNTALREDFGYKDFIWVFSG FT RRGAHCWVSDKRARALTDVQRRNVLDYVNVIRDRNTDKRLALKRPYHPHLARSLEQLKP FT FFVSIMLEEQNPWEDDQHAIQTLLPALYDKQLIDSLKKYWLDNPRRSSKEKWNDIDQIA FT TSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVEVTKQTIHLLKAPFCIHPATGNVCV FT PIDESFAPEKAPKLIDLQTEMEKNNDVSLTALQPFINQFQAYVSSLLKNELGSVKRERE FT DDDEPASLDF" FT CDS 3763..4098 FT /note="len: 111, CAI: 0.10, similar to small nuclear FT ribonuclearproteins" FT /db_xref="GOA:P40567" FT /db_xref="InterPro:IPR000504" FT /db_xref="InterPro:IPR012677" FT /db_xref="SGD:S000001448" FT /db_xref="UniProtKB/Swiss-Prot:P40567" FT /protein_id="CAA86079.1" FT /translation="MVEPARKKQRIDRDTHHTVAEPVTEAKNTLYVSQLNEKINMQRLR FT VNLFLLFATFGEVLKVSMNFKKQRGQAFITMRTIDQASLAQISLNGERFFGKPLKVEFS FT KSETKTL" FT misc_feature 3967..3990 FT /note="Eukaryotic putative RNA-binding region RNP-1 FT signature" FT CDS 4669..6399 FT /note="orf, len: 576, CAI: 0.12" FT /db_xref="GOA:P40568" FT /db_xref="InterPro:IPR013218" FT /db_xref="InterPro:IPR018247" FT /db_xref="SGD:S000001449" FT /db_xref="UniProtKB/Swiss-Prot:P40568" FT /protein_id="CAA86080.1" FT /translation="MSLEPTQTVSGTPPMLHQRTHKQVYPLRMETIPILESDSKATLQS FT NEPTQKDEEETEYFENKQSVSNLSPDLKFKRHKNKHIQGFPTLGERLDNLQDIKKAKRV FT ENFNSSAPIADDNHSGDATANATANATANATANVNASAMPAPYMPYYYYYHPMNAPTPA FT MIPYPGSPMHSIMPNSSLQPFYSQPTAAGGPDMTTPQNISSSQQLLPAPQLFPYGSFHQ FT QQLQQPHYIQRTRERKKSIGSQRGRRLSMLASQANGGSTIISPHKDIPEEDFYTVVGNA FT SFGKNLQIRQLFNWCLMRSLHKLELKAKNQEEEGELEHLTKKSKLESTKAETDYVDPKR FT LAMVIIKEFVDDLKKDHIAIDWEDEEKYEDEDEEKILDNTENYDDTELRQLFQENDDDD FT DDDDEVDYSEIQRSRRKFSERRKALPKEPKKLLPNSKNVENTKNLSILTSKVNAIKNEV FT KEWAVTLDTSRPDLEWQELTSFSSQPLEPLSDTEEPDLAIADVETKLETKVDELRYQSH FT ILNSHSLALNEITNSKVNKLNIETMRKISSETDDDHSQVINPQQLLKGLSLSFSKKLDL FT " FT misc_feature 5860..5898 FT /note="EF-hand calcium-binding domain" FT CDS complement(6525..7484) FT /gene="sts1" FT /note="len: 319, CAI: 0.13, sts1 gene, STSI_YEAST P35188" FT /db_xref="GOA:P38637" FT /db_xref="InterPro:IPR013868" FT /db_xref="SGD:S000001450" FT /db_xref="UniProtKB/Swiss-Prot:P38637" FT /protein_id="CAA86081.1" FT /translation="MMGFEWGFKPSSKITQSTVSSQGTGNVMIPTAGVKQKRRYANEEQ FT EEEELPRNKNVMKYGGVSKRRPQPGSLIRGQPLPLQRGMELMNKNQLQQLLVDLMTKHP FT EIQQSVHTRVIGLDFSIQKCLDMLKQKSEAVYQSIPYNRSYESNKLDDYAFVRMKPQIL FT EFLNCLVDFILDNIPPRLENLHASLKFLDICTELVIKLPRFELASNNYYYDKCIEQLSH FT VWCTLIEHVARDRIILLADNSSVWKSHMTRLQVYNEHSNGLLERPLQLFKSLDMGSPSA FT ASSSTLSLQESIIYHHDTMTANENNNNSGSAATDSPFN" FT CDS 7724..9019 FT /note="len: 431, CAI: 0.17, YST1_YEAST P35184 HYPOTHETICAL FT 24.4 KD PROTEIN IN STS1 REGION" FT /db_xref="GOA:P35184" FT /db_xref="InterPro:IPR001680" FT /db_xref="InterPro:IPR011046" FT /db_xref="InterPro:IPR015943" FT /db_xref="InterPro:IPR017986" FT /db_xref="InterPro:IPR019781" FT /db_xref="InterPro:IPR019782" FT /db_xref="SGD:S000001451" FT /db_xref="UniProtKB/Swiss-Prot:P35184" FT /protein_id="CAA86082.1" FT /translation="MEPQEEFITTEEVEQEIVPTVEVEQDVPVDIEGENDDDDEMMNDD FT EEALEVDMSNNSLTYFDKHTDSVFAIGHHPNLPLVCTGGGDNLAHLWTSHSQPPKFAGT FT LTGYGESVISCSFTSEGGFLVTADMSGKVLVHMGQKGGAQWKLASQMQEVEEIVWLKTH FT PTIARTFAFGATDGSVWCYQINEQDGSLEQLMSGFVHQQDCSMGEFINTDKGENTLELV FT TCSLDSTIVAWNCFTGQQLFKITQAEIKGLEAPWISLSLAPETLTKGNSGVVACGSNNG FT LLAVINCNNGGAILHLSTVIELKPEQDELDASIESISWSSKFSLMAIGLVCGEILLYDT FT SAWRVRHKFVLEDSVTKLMFDNDDLFASCINGKVYQFNARTGQEKFVCVGHNMGVLDFI FT LLHPVANTGTEQKRKVITAGDEGVSLVFEVPN" FT misc_feature 8384..8428 FT /note="Beta-transducin family Trp-Asp repeats signature" FT CDS complement(9257..9622) FT /note="orf, len: 121, CAI: 0.15" FT /db_xref="GOA:P40569" FT /db_xref="InterPro:IPR000679" FT /db_xref="SGD:S000001452" FT /db_xref="UniProtKB/Swiss-Prot:P40569" FT /protein_id="CAA86083.1" FT /translation="MSTKLPIVISNGTAFKKVPVQLLLNSGSEAQHGLPRNADSQPARP FT RTGITRTCGQCGEIKTSLQWREGPNGAACLCNACGLFFRKLILRFGRAAAKRYMEQIKG FT TGTKRRIPKELTGTVRF" FT misc_feature 10188..10188 FT /note="ambiguous base, A or C" FT CDS 10222..11052 FT /note="orf, len: 276, CAI: 0.07" FT /db_xref="GOA:P40570" FT /db_xref="UniProtKB/Swiss-Prot:P40570" FT /protein_id="CAA86084.1" FT /translation="MAFLQGKKGKGYFNDEGLDDKLIQKGKGAGHRKEMLHLEDDNGRQ FT RSVIANLQKFVYCCLYLRFIKDGSLFLILLGWIISSLCDFIQELTLRYLKKNYLEVGRD FT NDQEDDESLAIRGLETPIVRMIINKAIRYYQGLILLETAYCIVYHIRLDVSRDICSKPY FT GFVIMLLIREFTCPVPTAFPSKLLLVLLDILLLFCQIVIINGSLSSSLQNVKLIVKELN FT AEEEGALNILKLNTWHMDATGPELIVLKNHDKSIPQQADGDDATEITPLLNIAE" FT CDS 11186..11620 FT /note="orf, len: 144, CAI: 0.10" FT /db_xref="GOA:P40571" FT /db_xref="InterPro:IPR007175" FT /db_xref="SGD:S000001454" FT /db_xref="UniProtKB/Swiss-Prot:P40571" FT /protein_id="CAA86085.1" FT /translation="MGKKAHGGKMKPEIDENGTLLVPPPRTIANQDHFHRLNYLYQISA FT YQTRARQKARTDAHTPLARNYIKSMDLISKKTKTSLLPTIKRTICKKCHRLLWTPKKLE FT ITSDGALSVMCGCGTVKRFNIGADPNYRTYSEREGNLLNS" FT misc_feature 11453..11470 FT /note="Cytochrome c family heme-binding site signature" FT CDS 11866..12663 FT /note="orf, len: 265, CAI: 0.10" FT /db_xref="GOA:P40572" FT /db_xref="SGD:S000001455" FT /db_xref="UniProtKB/Swiss-Prot:P40572" FT /protein_id="CAA86086.1" FT /translation="MSGTRCLLGVGLPVDVTATETLTHDEQGPGVEPGPCSRGSSIDGL FT LPSLLGPHDDVDDDSAAFHKYMTLSRDGAGAIHAPSLVEDASRNDDDDDDEDDDDSSMS FT RDLSKALDMSSSSSSSPRVQSRRHRSSVSAISAILHQGKSGREDITGSLSVPAEQEKLS FT FLAKASSIFFRRNSMPRDKHTHSVCPASRPDSERFIVTSAAAQSLRRQQQLEDAQYARV FT ITNFRTIGWCSPSEIESVEYKRSLINAEWDEKISLLSHAQCYK" FT misc_feature 12274..12297 FT /note="ATP/GTP-binding site motif A (P-loop)" FT misc_feature 12384..12528 FT /note="near identity with bases 2 to 146 upstream of FT SCASP3A J03926 S.CEREVISIAE ASPARAGINASE II GENE (ASP3)" FT CDS complement(12794..13357) FT /note="len: 187, CAI: 0.09, possible regulatory protein FT with PROSITE matches to leucine zipper and fos/jun basic FT domain" FT /db_xref="GOA:P40573" FT /db_xref="InterPro:IPR004827" FT /db_xref="InterPro:IPR011700" FT /db_xref="SGD:S000001456" FT /db_xref="UniProtKB/Swiss-Prot:P40573" FT /protein_id="CAA86087.1" FT /translation="MSAKQGWEKKSTNIDIASRKGMNVNNLSEHLQNLISSDSELGSRL FT LSLLLVSSGNAEELISMINNGQDVSQFKKLREPRKGKVAATTAVVVKEEEAPVSTSNEL FT DKIKQERRRKNTEASQRFRIRKKQKNFENMNKLQNLNTQINKLRDRIEQLNKENEFWKA FT KLNDINEIKSLKLLNDIKRRNMGR" FT CDS 12804..13403 FT /note="This orf is slightly longer than the one in the same FT position on the complementary strand but is disregarded on FT the grounds that the complementary orf has a better FT positional base preference score" FT /db_xref="GOA:Q03885" FT /db_xref="SGD:S000028799" FT /db_xref="UniProtKB/Swiss-Prot:Q03885" FT /protein_id="CAA86088.1" FT /translation="MFRLLMSFNNFKDLISLMSLSFAFQNSFSLFNCSIRSRSLLICVF FT KFCSLFMFSKFFCFLRMRNRCDASVFFLLRSCLILSSSLEVLTGASSSFTTTAVVAATF FT PFLGSRSFLNCETSWPLFIMLMSSSALPLLTSSNDSKREPSSESLDIRFCRCSERLFTF FT IPFLLAMSMFVDFFSHPCFALILTNKTICLRNYHWL" FT misc_feature complement(12983..13027) FT /note="fos/jun DNA-binding basic domain signature" FT CDS 13847..14584 FT /note="len: 245, CAI: 0.13, possible regulatory protein" FT /db_xref="GOA:P40574" FT /db_xref="InterPro:IPR004827" FT /db_xref="InterPro:IPR011616" FT /db_xref="SGD:S000001457" FT /db_xref="UniProtKB/Swiss-Prot:P40574" FT /protein_id="CAA86089.1" FT /translation="MALPLIKPKESEESHLALLSKIHVSKNWKLPPRLPHRAAQRRKRV FT HRLHEDYETEENDEELQKKKRQNRDAQRAYRERKNNKLQVLEETIESLSKVVKNYETKL FT NRLQNELQAKESENHALKQKLETLTLKQASVPAQDPILQNLIENFKPMKAIPIKYNTAI FT KRHQHSTELPSSVKCGFCNDNTTCVCKELETDHRKSDDGVATEQKDMSMPHAECNNKDN FT PNGLCSNCTNIDKSCIDIRSIIH" XX SQ Sequence 17421 BP; 5466 A; 3567 C; 3566 G; 4822 T; 0 other; gatccaattg cgtggtgtca atttggatcc gtcagttaaa atccctgcaa agccattcct 60 atccacccac gctcccatag aaaatgacac gtttttcgag gatgctgata aagtcagttt 120 catcaatcac cccttagttc ttgatgatat cgaacagcat atcatcagat tgaaatcact 180 gggttacaat accattcgtt tacccttcac ctgggaatct cttgaacatg ctggtccagg 240 acagtacgat tttgactata tggattatat cgtcgaggta ctaaccagga ttaacagcgt 300 acaacaaggt atgtacattt atttggaccc tcaccaagac gtctggtcta ggtttagcgg 360 tggatctgga gcaccgctat ggaccttata ctgtgcaggg tttcaacctg caaacttcct 420 ggccaccgat gctgcaatct tacataatta ttatattgac cccaaaacgg gcagggaagt 480 tggcaaagat gaagagtcct accctaagat ggtttggcct acaaactact tcaaactggc 540 gtgtcaaaca atgtttacgt tattctttgg tgggaaacaa tatgctccta agtgcacaat 600 taatggagaa aacatacagg attacttgca aggaaggttt aatgatgcaa tcatgacact 660 gtgcgcaaga attaaagaaa aggctcctga gttgtttgag agcaactgca ttattggatt 720 agagtctatg aacgagccaa actgtggtta cattggtgaa acaaatctcg atgtgattcc 780 gaaagagaga aatttgaaat tgggcaaaac gccaacggca tttcaaagct ttatgctggg 840 tgaaggtatt gagtgcacaa tagatcaata taaaaggaca ttttttggat tttctaaggg 900 aaaaccgtgc acaatcaatc ccaaaggcaa aaaagcttgg ctgagtgcag aggaaagaga 960 tgcgatagat gcgaagtata attgggaaag gaaccctgaa tggaaaccag acacttgcat 1020 ttggaaactc catggtgttt gggagattca gaatggtaaa cgccctgttt tactcaaacc 1080 aaattacttt agccaacctg atgcaacggt atttataaac aatcattttg ttgactatta 1140 cactggaatt tataacaagt ttagggaatt cgatcaagaa ttgtttatta taatccaacc 1200 gccggtaatg aagccaccac ccaatttaca aaattctaaa atattggaca ataggacgat 1260 ttgtgcatgt catttttatg atggtatgac actaatgtat aagacatgga ataaacgaat 1320 tggcatagac acctatggac tagtaaacaa aaaatactca aatcctgcct ttgctgtagt 1380 gcttggcgaa aacaatatac ggaaatgcat taggaagcaa ttatcagaaa tgcaaaagga 1440 cgctaaatcc atgcttggaa aaaaagtacc tgtattcttc accgaaattg gtattccatt 1500 tgacatggac gacaagaaag catatattac aaatgactat tcttcacaga ccgctgcatt 1560 ggatgctctt ggatttgcat tagaaggaag taatctttcg tacaccttat ggtgttattg 1620 cagtattaat tcacatatat ggggtgacaa ttggaacaat gaagattttt cgatttggtc 1680 cccggatgac aaaccactct atcacgatac ccgagcaaaa actcctactc ctgagccatc 1740 tccagcctct actgtggctt cggtatccac ttctacatct aaatcgggtt cttcacaacc 1800 accaagtttc ataaaaccag ataatcattt agatttggat agtccctcgt gcactttaaa 1860 gagcgacttg tcagggttca gagctcttga tgctataatg agaccattcc ccatacaaat 1920 tcacggaaga tttgagtttg ctgagtttaa cttatgtaat aaatcctacc ttttgaaatt 1980 agttggtaaa acgacacctg aacagataac tgtccctaca tatattttta taccacggca 2040 ccattttaca ccaagccggt tgtcaattcg ttcatcatca ggtcattata cctataacac 2100 tgactaccag gttcttgaat ggtttcacga gcctggccat cagttcattg aaatttgcgc 2160 aaaatcgaag tcaaggccca acacccctgg aagtgacact tcgaatgact taccagcgga 2220 atgcgttatc agctaaacaa aaattgaacc aaaagctata gtagtcatat atatatatat 2280 acaccctttt tattgttaca aaaagatttc accatcagaa atctaaagaa gccggttcat 2340 catcatcttc acgttctctt ttcactgaac ccagttcatt tttcaaaaga gaactcacat 2400 atgcttggaa ctgattgata aaaggttgta aagctgttaa tgaaacatca ttatttttct 2460 ccatttctgt ttgaagatca attagcttag gtgctttttc aggtgcaaag gattcatcaa 2520 taggcacaca gacattcccc gtagcaggat gaatacaaaa aggggccttt aacaaatgaa 2580 ttgtttgctt tgtaacttcc acatccagct tcggataaag agtcatcaat acgagatctt 2640 ccttacattc acgtaactta attatgtgag agtcttgctt ggggcctttg aagagcgatg 2700 tagctatctg atctatatca ttccacttct ctttgcttga cctccttgga ttgtccagcc 2760 aatacttctt taatgaatca atcaattgtt tatcatataa tgcaggcaat aaagtttgga 2820 tagcatgttg gtcatcttcc caaggatttt gctcttcgag cataatgctg acaaagaaag 2880 gtttcaattg ctccaaagaa cgagcaagat gagggtgata aggcctcttc aaagccaatc 2940 gcttgtcagt atttctgtct ctaatcacgt tgacataatc taaaacgttt cttcgttgta 3000 catccgtcaa agcccgtgcc cgtttgtcgc ttacccaaca atgagcacca cgtctacctg 3060 aaaataccca gatgaagtcc ttataaccaa aatcctctct tagggccgtg ttcgtaattt 3120 tcattgccaa agatataaat ttccagcact tagagcaaac ttgggctccg gagcaacacg 3180 ttctgaaggc atcgtaatca tccatatcaa tatcaaacac caactccttc tctaaagctt 3240 tcaattcgct ttttaataga gtatcacgtt ctcttggcgg tttgttatat atggcaccga 3300 tttcaaatct gtctgggttg gctttttcta tttgtgcttt gaaatcttgc acagagttaa 3360 aagaattata ccttttgtaa gcacctgacc tgaacgccat agcgaattct ctgttaatca 3420 tatccctaga aggtttgggc gaatgattca gccagttgaa aatgtgtttg aatggataga 3480 gcgacttata gtagtactcc atgtctgagg agcttggccc attagtcttt actgaattgg 3540 tcatgatgtt tataaaacag ttttttgagt tgctaaaact aatttttgct agtattatgg 3600 cacgcttttc tcttcagctt caaagtattt ttgattaatt ttttatcttt ttggcgttat 3660 gaaacttttc aactgaaaga aaacaatagg taaaagtggc aaagggcact gaccgagcaa 3720 ctgtttcgaa actcacgcat cattcacacg taggatatag taatggttga accagcaagg 3780 aaaaagcaga ggattgatcg cgatactcat cacactgtgg ctgaaccagt aacggaagct 3840 aaaaatacgc tgtacgtgag ccagcttaat gaaaaaatta atatgcaacg actgcgagta 3900 aacctttttt tgctctttgc tacgtttgga gaggtactga aggttagcat gaatttcaag 3960 aaacagcggg gccaagcctt tatcaccatg agaaccatcg accaggccag tctggcccag 4020 atttcattaa acggcgagcg attctttggt aagcctttga aagttgagtt cagcaagagt 4080 gaaactaaaa cactatgact ggcttaacgc tctattcata gcagcacgta tataccgaga 4140 agagctgcca taggggcaca tcaaagtcaa gagcgcagaa ccaaaccaaa atgtttatat 4200 ccaaacaacc cggcgttata gatggtcgtc aacggacaaa taatatcaag gcatgtatca 4260 atatggagta gatatagaat ctacaaaaat ctgtagcaga aagagtctcc cgaaaagaca 4320 tactgcagaa cggccgctta ttcctcactt caattgctta aataatacaa agggcaaacc 4380 acagagtacc ccattgccaa aagacgttta ttacattttg gaagtgataa tttagtatat 4440 aagacagctt actatatgat gaattacagt gtagttcagc gtttatatgt ggcttcgttt 4500 aaaatgatat atatttctag taaaagcaaa aattcacaaa tgataaacaa atcaaaataa 4560 acatcaaaag aaccgccaat tgataaaagc acaaagtacc aggcagagtt gtgaaaccgg 4620 gcctcttcta ttgtaccaca cacaaatttt tctttattta ggtagaggat gagtctggaa 4680 cccacacaaa cggtctccgg tacgccgccg atgctgcatc aaagaacaca caaacaagta 4740 tacccattgc ggatggaaac tatcccaata ttggaatccg actccaaggc tactctacaa 4800 agcaacgagc ccacccagaa agatgaggag gagaccgaat attttgagaa taaacaatcc 4860 gtgtcgaatt tgagccccga tttgaaattc aaacgacaca agaataaaca tatccagggg 4920 ttccctactc tgggcgaaag gctggataac ctgcaagata taaaaaaggc caagagagtg 4980 gagaatttca attcttctgc gccaattgct gacgacaatc atagtggaga tgcgactgca 5040 aatgcgactg caaatgcgac tgcaaatgcg actgcgaatg ttaatgcaag tgcaatgccc 5100 gctccatata tgccttatta ctattactac catccgatga atgcaccaac tcctgcaatg 5160 ataccatatc ctggatcacc aatgcattcg attatgccca actcctcatt acagcccttt 5220 tattcgcaac ccactgctgc aggcggtccc gatatgacta ctccccaaaa tatatcttca 5280 tcacaacaat tgctgccagc tccgcaattg tttccgtacg gatcattcca tcaacaacaa 5340 cttcagcaac cacactacat tcaacgaaca agggaaagga aaaaatcaat cggaagtcag 5400 agaggtagaa gattgtctat gttagcatct caagctaatg ggggaagcac tattatatct 5460 ccgcacaagg atattcctga agaggatttt tacaccgtgg ttggaaatgc gtcttttggt 5520 aaaaatttac aaatacgaca gcttttcaac tggtgtttaa tgagatctct gcataaattg 5580 gagttgaagg ctaaaaacca agaggaagaa ggggaacttg aacatctgac caaaaaatcc 5640 aagctcgaat caacaaaggc agaaactgat tatgtggatc ccaaacgtct ggctatggtg 5700 ataataaaag agtttgtcga tgatcttaaa aaagatcata ttgcgataga ttgggaagat 5760 gaggaaaaat atgaggatga agatgaggag aagattctgg ataatactga aaactacgat 5820 gacacggaac tgcgacaact gtttcaggaa aacgacgacg acgacgacga cgacgatgag 5880 gtggactact cggaaataca gaggtctaga cgtaaattta gtgaaaggag aaaagcccta 5940 ccgaaagaac caaaaaaact attacctaat agcaaaaacg tggaaaacac aaagaatctt 6000 agcattttaa cgagcaaggt gaacgcgatc aaaaatgaag tgaaagaatg ggcagtcact 6060 ttagacactt cgagaccaga tcttgaatgg caagaattga cttcattctc atcacaacca 6120 ctggaaccgt tgtcggatac agaagagcca gaccttgcga ttgcagatgt tgagacaaag 6180 ttagaaacaa aagtcgatga gctaaggtac cagtcgcata tattaaactc gcactcacta 6240 gccttaaacg aaataacaaa ttcaaaagtg aataaattga acatagaaac aatgagaaag 6300 atctcaagcg aaacggacga tgaccactca caagtgatta atcctcaaca gctgttgaag 6360 ggattaagtt tatctttcag taaaaaactg gatttatgaa ataaaagaaa aaatcaaaaa 6420 aaaatcggat acttctgcat atgtaacatt acacagtcat acatttatat atacatatat 6480 atacatatta atgtatttga aaaagcaaaa gaaccattct atccttagtt aaagggcgaa 6540 tcagtagcag cgctaccact attgttattg ttttcgtttg ctgtcatggt atcgtggtgg 6600 taaataatac tttcttgaag tgataatgtt gatgacgatg ctgctgaagg gctacccata 6660 tctaaagatt tgaacagctg gagtgggcgt tccaataacc catttgaatg ttcattgtat 6720 acctgtaatc ttgtcatatg acttttccag acggagctat tatctgctaa taaaattatc 6780 ctgtcacggg caacatgttc aataagcgta caccatacgt gagacaattg ttcaatgcat 6840 ttatcgtagt agtaattatt actagctaat tcaaatctgg gcaatttgat aactaattcc 6900 gtgcaaatgt ctaagaattt taatgatgcg tgcaaatttt ccaaacgtgg tggaatgtta 6960 tccagtatga aatccaccaa acagtttaag aactccagaa tttgaggttt cattctcacg 7020 aaagcatagt catctaattt attactctca taagacctat tgtaaggtat gctctggtaa 7080 acggcttctg atttttgttt caacatgtcc agacactttt gtatactgaa gtctaatccg 7140 atgactctcg tatgtacgct ttgttgtatt tctggatgtt ttgtcatcaa atccaccaac 7200 aactgctgta attggttctt gttcattagt tccatgcctc gttgcaaggg cagaggctgc 7260 cctctgatga gcgatcctgg ctgaggcctc ctcttggaga cgcccccata tttcatcaca 7320 ttcttgttac gaggtagttc ttcctcttct tgctcctcgt tggcataccg ccttttttgt 7380 ttcactccag cagttggaat cattacattg cctgtgcctt gtgaactgac tgtactctgt 7440 gttattttac tgctgggttt aaaaccccat tcaaacccca tcataatgct atactgtcct 7500 gtgtttgttg cttttgccag gtaccttcga acacactaag tgagaatact tggttaagta 7560 tatttttaag taagaaattc ccactcgccg cattatcacc cgcccgccgt ttctttttct 7620 ggcaaaattt tcactatgaa taactaaaga gatacattcg atgggcttta gatgaggcct 7680 tttgaagacc aaaacagcac caaatagcga cacattaagc gtaatggaac ctcaagaaga 7740 gtttataact accgaagaag ttgagcagga gattgtgccc actgtggagg tcgaacaaga 7800 cgttcccgtt gatattgaag gagagaatga cgacgatgat gaaatgatga atgatgatga 7860 ggaagctttg gaggtcgaca tgtccaacaa ctcgcttacc tatttcgata agcacacaga 7920 ctccgtgttt gccattggcc atcatcctaa cctgccgcta gtatgtaccg gtgggggtga 7980 taacttggca catctttgga catcacattc acagccaccc aagtttgctg gcactctaac 8040 cggttatggc gaatctgtga tttcatgttc tttcacttct gaagggggct tcttggtcac 8100 tgccgatatg tcggggaagg ttcttgtaca catgggtcaa aaaggtggcg ctcagtggaa 8160 gttggcatcg caaatgcaag aagtcgaaga gattgtttgg ctgaaaactc atcccactat 8220 agcaaggacg tttgcgtttg gtgcaactga tggatctgtt tggtgctacc agattaatga 8280 gcaggatggt tctttggaac agttaatgtc tggttttgta caccagcaag attgctctat 8340 gggtgaattc attaacaccg acaagggtga aaatacgctg gaattagtca cttgttcttt 8400 ggatagcact attgtggcat ggaattgctt cactggccaa caattattta agatcacaca 8460 ggcagaaatc aagggattag aagctccatg gatttcccta tcattagctc cggaaacttt 8520 gaccaagggt aactcgggtg tcgtggcatg tgggtccaac aatggtcttc tggcagtaat 8580 taattgtaac aatggcggtg cgattttaca tttatctaca gtgattgaac taaagccaga 8640 acaagacgaa ttagatgcct ccattgaatc catttcttgg tcatccaaat tctcccttat 8700 ggccattggc cttgtctgcg gtgaaatact cttatatgat acaagtgcat ggagagtaag 8760 acacaagttt gttctcgaag attctgttac aaaacttatg tttgataatg atgacttatt 8820 cgcatcgtgt atcaatggta aggtttacca gtttaatgca agaactggcc aagagaagtt 8880 tgtttgtgtg ggccataata tgggggttct tgattttata ttactgcatc ctgtggcaaa 8940 taccggcacc gagcagaaga gaaaagtaat aactgcaggt gatgaaggtg tatctctggt 9000 gttcgaggta ccaaactgat agatagtcgc gtatacataa ataacaaaaa aacaaattca 9060 ataacataaa ataaaaatac ttttacatac agaagaagaa actttatata ttcgacaaag 9120 gaaaatgtaa aaaaaaaaaa cacattattt taaaagaact gcgctcatta tcgtcgttaa 9180 cgattttatt attacatgtt gaacgttaca ttgtcttttt gtcccgatag gttgaaagct 9240 gaaaaagtat aatgggtcag aatctgacag ttccggtaag ttctttgggg atccttctct 9300 tagtcccggt acctttaatt tgctccatgt atcttttagc agctgctcta ccgaagcgca 9360 gaatcaattt tctaaaaaac aacccacaag cattacacag gcaagcagca ccgttagggc 9420 cctccctcca ttgtaatgaa gtcttaatct ctccacattg cccacatgtc ctagtaatgc 9480 ccgttcttgg tcgagcaggc tgagagtcag cgttcctagg gaggccatgt tgtgcctctg 9540 atccgctatt caacagcaat tgaacgggga cttttttgaa ggctgttccg tttgaaatca 9600 caataggcaa cttagtggac atagcgaccc tgtaatgtta tgtttctagc taggaacaga 9660 aagtgccagc tttttgagca gttaaagagt aaaatgttta tgtggtttca cggacttaca 9720 tgtgaaagac tagcctggcg ctatctaaat tcatgatgaa actcgatggc cctttccatg 9780 gcacaaaaat cttgacacat ggatgtgcgc ggcggcggta accgcaccaa ggaaaaaagg 9840 gtccaatgcc aagaaataat aaaacggacc cttttttctt tttttttgaa ataaaattga 9900 aagagaaatg caaacacttt tcaggtttga aaagaaaaga aaacgtcaag aatcttacgc 9960 caaaagtgcc taagattcaa gtatctctga aaggcgtacc attttcaaca aggggcatag 10020 gtggccgcaa actaggataa ttgacaactt agtttcatat tgacaatgtc atcgcaattg 10080 aggagatagc cataattcgg gagggtacaa aacctgacct gctagtgttc aactaatgca 10140 tcatgggtac tatagagagc attctagtgg tagaaaaaaa aaaaaaaaca aactttaaac 10200 cgggtaatat aaacttctca tatggctttt ctccagggaa agaaagggaa gggatacttc 10260 aatgacgaag gcttagatga caagctaata cagaaaggga aaggagcagg gcatcggaag 10320 gaaatgttgc atttggaaga tgacaatgga cgacaaaggt cagtgatagc gaatttgcag 10380 aaattcgttt attgctgcct gtacttgagg tttatcaaag atggatcatt attcttgatc 10440 ctcctggggt ggataatttc atcgctctgt gatttcattc aggaattgac actcaggtac 10500 ctgaagaaga actatttaga ggtgggccgc gacaatgatc aggaagatga tgaaagtctt 10560 gccatcagag ggttagaaac acctattgta agaatgataa taaacaaagc catacgatat 10620 taccaaggcc taatacttct agaaacagcg tactgtatag tataccacat taggctagac 10680 gtatcgagag acatatgttc caaaccgtac ggatttgtga taatgctttt gataagggaa 10740 tttacttgtc cggtacccac agcgtttcct agcaagctac ttctggtact actcgatatt 10800 ttattacttt tctgccagat tgtaataata aacggctcac tgagctcgag tcttcagaac 10860 gtgaaactta ttgtcaagga gttgaatgca gaagaagagg gcgcactcaa cattctcaaa 10920 cttaatacct ggcacatgga tgcaaccgga ccggaactca tagtactcaa gaatcatgac 10980 aagtcgattc ctcaacaggc agacggggat gacgctacag agatcactcc tctactgaat 11040 atcgccgaat aaattcaaga aaggaaaaga aaaaaaatta ccaaaatgaa aagaacggaa 11100 aaaaaagatg aacagaaaat aaaacaatac gtggttcttc tactgtcctt cccacatcgc 11160 cgacagagaa aagacaagca aaaagatggg caagaaagca cacggaggaa agatgaaacc 11220 tgagatcgac gaaaatggta ctctgctagt accgccacca aggacgattg cgaaccagga 11280 ccatttccat agattaaact acctctacca aatatccgct taccaaacaa gagcaagaca 11340 gaaagcaaga acagacgcac atacgccttt ggcacgcaat tatatcaaat caatggacct 11400 aattagtaag aaaaccaaga catcactgct tcctacgata aagagaacaa tttgtaaaaa 11460 atgccatcgg ttgttatgga ccccaaaaaa actggaaatc acatccgacg gagcgctttc 11520 ggtaatgtgt gggtgcggta ccgttaaacg ttttaatatt ggcgccgatc ctaattacag 11580 gacctactcg gagcgggagg gtaatctact aaattcttag ggttattggt agggttttgg 11640 accaatgttt tgagcaggac aaaaatgcgg agtttccaga ttttctttaa gagccgaccc 11700 cccaccccct tgcccctata catggggtac gtgcctgtat tttgagggaa aactacgaca 11760 taaaacacag ggaaaaaaac gagacgcccg tttgaagaag gtaatgtagg attccgtctt 11820 gccagcatag cggataaaca ccgcaaggag gtgttgtggt cggtaatgag tggcacgagg 11880 tgtttgctag gcgtcggact accagttgat gtgactgcta cggaaacttt gactcatgat 11940 gaacaaggac caggtgtaga gccaggaccg tgttcgcgag gaagttctat agatggtctg 12000 ctgccctcgt tgctcggtcc acatgatgat gtggatgacg attcggcggc ttttcacaag 12060 tacatgacac tatcgcgaga tggcgcaggc gccatccatg ctccgtcatt agtcgaagac 12120 gcctcaagga acgacgacga cgacgatgat gaagacgacg acgacagttc catgtcgcga 12180 gacctatcca aggctctaga tatgtcatcg tcatcatcgt ccagcccgcg cgttcaaagt 12240 cggcggcacc gtagttctgt gagcgcaata tctgcaatct tacaccaagg aaaatctggc 12300 cgcgaagaca taactggaag ccttagcgtt ccggcagaac aagaaaaact cagttttctt 12360 gccaaagcct cgagtatttt ctttcgaagg aacagtatgc ccagagacaa acatacgcat 12420 tcagtatgtc ccgctagccg cccagattcc gagagattta tcgtcacatc tgcagccgcg 12480 cagtctttac gccgccaaca acaactggaa gacgctcagt acgctcgagt tattacaaac 12540 tttcgtacta taggatggtg ctctcccagc gagatagagt ctgtggaata taaacggtcc 12600 ttgatcaatg cggagtggga cgaaaagatc tcgcttttgt ctcacgcgca atgctataaa 12660 taataaatat acatatatat atatttatat gtagatagat gtgtgtatat atatgctagg 12720 taaagaaacg gaaaaatcga aaaatcgaag ttggagagga aaaacaagac atcaggcccg 12780 cacgtttcgc gggctacctg cccatgttcc gtctcttaat gtcattcaac aatttcaaag 12840 acttaatctc gttaatgtca ttgagctttg ctttccaaaa ctcattttcc ttgttcaatt 12900 gctctatacg atcgcgaagt ttgttgattt gcgtgtttaa gttctgcagc ttattcatgt 12960 tctcaaaatt cttttgtttc ttgcgaatgc ggaaccgctg cgacgcctct gtgttctttc 13020 ttctccgctc ttgcttaatc ttatccagtt cgttagaagt gctcacggga gcttcctctt 13080 cttttacaac aactgctgtt gttgcggcaa ccttcccctt tctcggctcg cggagcttct 13140 taaactgcga gacatcctgg ccattattta tcatgctaat gagctcctcc gcgttgccac 13200 tgctaaccag cagcaatgat agcaagcgcg agcccagctc tgaatcgctt gatatcaggt 13260 tctgtagatg ttccgaaaga ttgttcacgt tcataccctt cctgcttgca atgtcaatgt 13320 ttgttgattt cttttcccac ccttgtttcg cactcatatt gacgaacaaa acaatttgtc 13380 ttcgtaacta ccactggtta taaatagtta aattcaagtt acctcgtgtt cttagtcatt 13440 ggctgcccgg ccttgactca cgccagtgac ctacaactat ggcgtttccg cttcccgccc 13500 aaaactgtgg tgttagaaag tagaaaaagg tgaaaaaagc gaaacctaaa accaaaaaaa 13560 aaaaataagt cacgtgcact cagtacccct tctattgtat tttagtttac ctattgggcc 13620 gggcgggccc cacaactgtg gcatctttca gatcattttt ttccagaatg catggaactg 13680 acgagtgaac ttttattcca cggaaaagga caaaaaggtg cagtaatgga atggtctttt 13740 tgcacggcag tgatgtcgct atcatatcaa tcactgaaag tgaagttaac catattacaa 13800 caagttcaca caacataaac agtgtaacta gcatattatc acagtcatgg ctctacctct 13860 gataaaacct aaggagtctg aggaaagcca cctcgctctt ttgtccaaga tccacgtgtc 13920 caaaaattgg aaactgcctc caaggttgcc ccatagagca gctcagcgga ggaaaagagt 13980 tcatcgactt cacgaagatt acgaaactga agaaaatgat gaggagctac agaagaaaaa 14040 acggcagaat agagacgccc aaagggccta cagagaacgc aaaaacaaca agttgcaagt 14100 gctggaggaa accatagagt cactgagtaa ggtcgttaaa aactacgaaa cgaaactaaa 14160 ccgcctccaa aatgaacttc aagcgaaaga atcggaaaat catgccctta aacagaaatt 14220 ggagaccctt actctgaaac aagcctctgt gcctgctcag gaccctatcc tgcagaattt 14280 gatcgagaat ttcaaaccaa tgaaggcgat acctattaag tacaataccg ctatcaagcg 14340 ccaccagcac tcgacagaac tgcctagctc tgtcaaatgc ggcttttgta acgacaacac 14400 tacttgcgtt tgtaaagaac tggaaacaga tcaccgtaaa agtgacgacg gtgtggccac 14460 agaacagaag gatatgtcga tgccacatgc agagtgcaat aataaagata accccaatgg 14520 gctctgtagt aattgtacta atatcgacaa atcatgtatc gacatccggt ccatcatcca 14580 ctgaagagag agaacttctt aatacttata aatacgtcat tgaacagctc aacttttgta 14640 acgtcaaaag aacgcacatg aaaggagtga cattgctttt ttctttgcaa gtttattact 14700 gtggttatgt gtaaagaatt agttcatgga cattggccgc agagtgcaaa agcgttttgg 14760 acaccccgcc tttggtgttc tcgccgccat attttgagac gttagtttcc gacgaattga 14820 gctgaagcgg tggacattat ctcaaggtac cgcttactat gcctatacat tcctgcaatt 14880 tttttttttt tttttttgat aagtattact gggtaatggg aagtataatc actaggcata 14940 ttatttttga cgcagaggag tggcagcctg tctactatgt aaatgtaatg gtagaaccgt 15000 tattataacg taaaatagat cgtacataag aaaaactgga cgcaaaccat ttaaatctaa 15060 atgcgaatat gcgtactgat tattaacatg ataccataat ttagatcttt ccttttgaaa 15120 gtcgtgtcaa attctagtat tggcggatga gatcctaatg tgctaaacaa tagagataat 15180 gggatccccg caaatttcat ttttaaattg ctttcctctt ctgagttgaa cacgaatttt 15240 tgagaatcta gctgtagtta gacgttacgc aaaagaagct ttggcgcaag caaatctcct 15300 tccatactgg tctcctttac ggctgtacga acactaccgt agtgacaaac tgaaaaacga 15360 ggatttggtg agcagtctgg aacaggtaga tgaatcataa agcgcagcaa ccatcctcga 15420 actgatgaca gtacgacttt tctccaaaat agatataaag aaaggctggt tattcgtgga 15480 gagttcagtc ctccgtatct aaccttgatg aattaaaact caggccagaa caatctcttt 15540 aacagacctc catacatact ctcggagcta tattttagtg cgatcaaact gcgaatagaa 15600 taaagcagac gcaagaggca aattacaaac tcttgcgctt cctttttagc gagcttgtta 15660 aagtagggtc tgaacgagag gctgtcacaa ttgcgttgcg ttatgcaaag gatataacac 15720 ggtgctgaag ttaaactgtg aaactataca agtggaggac cctttgagtt ttctgtagat 15780 aaaaaggaga atgtttcaga agagcgtcag agatctcgaa tgacagatcg gtggctacca 15840 cgaaatctta taggcgtttc tctgggctcc ctagttacgt atagcgctga cgtagtttag 15900 aagggcgcgc gcattttttc tattgttgcc tcttttctcg ctagctggct tttagcatca 15960 tgttctgcgg atattattct ccgcccggaa ggttcgtgga aggcctagaa tgagatctat 16020 caataacgct acgcagattt ctaatgttac atgtcacgtc gatctgacat atatctccgt 16080 caggttcgat ccagactctc tgcgcgcgta ccaagagctt tttgtttcaa taggaacgga 16140 atttccttta ttgaatgtgg caacgaactg cggagggtta ttagcttctt gacactttct 16200 tcgtccatta cgtagaccta acgttgaaaa ggagacctcg aagaaatttt aactcttggc 16260 acctcagaat aaacaaggtc atctagtgcg atggcaatgc ttcaaagtaa atggagaatt 16320 tcgaaggcta gcgtctctag ataaatctca gcctaaccct tttacacgaa gttttcccaa 16380 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaagggcggt tgtctttggc atatcgcgaa 16440 aataatagat cttatcaagg ggtttttaag tcatcctctg attattggaa gtcataatca 16500 cgttcaatgg tgggaggcct tcggaaaaga aaagaaaaga aaagaaaatt ttctcaatct 16560 gaaacagtct cttgtttacg ttacactggc aattttaacg gcgagactca tctgaaaaaa 16620 gctattcgac ttagtcctgt gtttttcatt acagataatc ctgatcaacg ggtgtacgtt 16680 tttccatttt aggtcagtat cctccctctg tgtttcaaac taagtataag cgcccaccct 16740 aattcgctcg tatccttgtg tcaacttctt tgctgctctg cagctgtaaa cagtttttgc 16800 gataagcctc acatatgtca gtgctgtaaa taccggaaat agaaagtcac tgtggtctgt 16860 accctcattt gatttacgcg gttagaaaag tggaaactct ttcttaaccg tgtaaatcaa 16920 gtatgtcatt tcaggaaact tcctcaattc ttggcgtact atattgagtt gccaatgtat 16980 gagagtggtc gatttcaatc ggcaacattc tatctcgcaa ttacgcaata aaaattgaca 17040 tggtatgtta ttttcatcct tcggattttt caaaccattc tgttataaga gatatgtacc 17100 atcaatcgcc gacagcgata ccctctttaa cctctagtaa gaaggacccg gcacttattg 17160 taatacgttt aggggaagta ggtaaatctg gaccggtaat acggcataac gatccatttc 17220 ggacatcggg gacatttctt ttttttcctt tattattttt tttttctaat gtccttacga 17280 atttcaggct ctaaccttat ttcttattag gacgtgtact cattgccatc gcaacaataa 17340 aaataaaaca ttaataaaaa attaattaga gcctgtaaca tagagatcaa cgctactgta 17400 gcgttagaag gacagtgaga g 17421 // |
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