EBI Dbfetch

ID   Z23135; SV 1; linear; genomic DNA; STD; INV; 1657 BP.
XX
AC   Z23135;
XX
DT   30-JUN-1993 (Rel. 36, Created)
DT   18-APR-2005 (Rel. 83, Last updated, Version 8)
XX
DE   L.donovani trypanothione reductase gene, complete CDS
XX
KW   NADPH:trypanothione disulphide oxidoreductase; trypanothione reductase.
XX
OS   Leishmania donovani
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmania.
XX
RN   [1]
RP   1-1657
RX   DOI; 10.1016/0166-6851(94)00034-4
RX   PUBMED; 7935607.
RA   Taylor M.C., Kelly J.M., Chapman C.J., Fairlamb A.H., Miles M.A.;
RT   "The structure, organization, and expression of the Leishmania donovani
RT   gene encoding trypanothione reductase";
RL   Mol. Biochem. Parasitol. 64(2):293-301(1994).
XX
RN   [2]
RP   1-1657
RA   Taylor M.C.;
RT   ;
RL   Submitted (28-JUN-1993) to the EMBL/GenBank/DDBJ databases.
RL   taylor m. c., Netherlands Cancer Institute, Molecular biology, Plesmanlaan
RL   121, Amsterdam, North Holland, The Netherlands, 1066CX
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1657
FT                   /organism="Leishmania donovani"
FT                   /strain="HU3"
FT                   /isolate="HU3"
FT                   /mol_type="genomic DNA"
FT                   /clone="LTR1,LTR3, LTR4,LTR6, TR-PCR1,"
FT                   /db_xref="taxon:5661"
FT   CDS             57..1532
FT                   /standard_name="NADPH:trypanothione disulphide
FT                   oxidoreductase"
FT                   /product="trypanothione reductase"
FT                   /EC_number="1.6.4.8"
FT                   /db_xref="GOA:P39050"
FT                   /db_xref="HSSP:1TYT"
FT                   /db_xref="InterPro:IPR004099"
FT                   /db_xref="UniProtKB/Swiss-Prot:P39050"
FT                   /citation=[1]
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAA80668.1"
FT                   /translation="MSRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPAL
FT                   VALGGTCVNVGCVPKKLMVTGAQYMDLIRESGGFGWEMDRESLCPNWKTLIAAKNKVVN
FT                   SINESYKSMFADTEGLSFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSW
FT                   PTRLGVPGDEFCITSNEAFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYR
FT                   GDLILRGFDTEVRKSLTKQLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQV
FT                   MLAIGVPRSQALQLDKAGVRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINE
FT                   GACVLLETVFGGKPRATDHTKVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPL
FT                   MHNISGSKHKEFMIRIITNESNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTI
FT                   GVHPTSAEELCSMRTPAYFYESGKRVEKLSSNL"
XX
SQ   Sequence 1657 BP; 370 A; 493 C; 511 G; 283 T; 0 other;
     cagcctcccc ctcccctcac cctctcgcga aaattcttcg cttctctcaa cggctgatgt        60
     cccgcgcgta cgacctcgtg gtgcttggcg ccggatctgg aggtctggag gcgggatgga       120
     acgcggccgt cacgcacaag aagaaggtgg ccgtcgtcga tgtgcaggcg acgcacggtc       180
     cgccggctct cgttgcgctc ggcggcacgt gcgtgaacgt cggctgcgtg ccaaagaaac       240
     tcatggtgac aggtgcccag tacatggacc tgatccgtga gtctggcggc ttcggatggg       300
     agatggaccg cgaatcgctc tgccccaact ggaagacgct catcgccgcg aagaacaagg       360
     tggtgaacag catcaacgag agctacaaga gcatgttcgc tgatacggag ggcctcagct       420
     ttcacatggg cttcggtgcc cttcaagacg ctcacacggt ggtggtgcgc aagtcggaag       480
     acccacacag cgacgtgctg gagaccctcg acacggagta catcctcatt gccaccggct       540
     cctggccgac gcgcctcgga gtccccggcg acgagttctg catcacgagc aacgaggcct       600
     tctacctcga ggatgccccc aagcggatgc tgtgcgtcgg cggcggctac atcgccgttg       660
     agtttgccgg catcttcaac ggctacaagc cttgcggtgg ctatgtcgac ctgtgctacc       720
     gcggcgatct tattttgcgc ggcttcgata cagaggtgcg caagagcctg acgaagcagc       780
     tgggggcgaa cggaataaga gtgcgtacaa acttgaaccc gacgaagatc acgaagaatg       840
     aggacggctc gaatcacgtt cacttcaacg atggcacgga ggaggactac gatcaggtca       900
     tgctcgcgat cggtgtgccg cgctcgcagg cactacagct cgacaaggcc ggcgtccgaa       960
     caggaaagaa cggtgccgtg caggtcgacg cgtattcgaa gacatcggtg gacaacatct      1020
     acgccatcgg cgacgtgacg aaccgcgtga tgttgacgcc ggtggccatc aacgaaggcg      1080
     cgtgcgtctt gcttgaaacc gtcttcggtg gcaagccccg cgccaccgac cacacgaagg      1140
     tcgcgtgcgc cgtgttctcc ataccgccga tcggcacgtg cggcatgacg gaggaggagg      1200
     cggcgaagaa ctacgaaacc gtcgccgtgt acgcgagctc cttcacgccc cttatgcaca      1260
     acatcagcgg cagcaagcac aaggaattca tgatccgcat catcacgaac gaatccaacg      1320
     gcgaggttct gggtgttcac atgctcggcg acagtgcgcc tgagatcatc cagagcgtcg      1380
     gcatttgcat gaagatgggt gccaagatca gcgacttcca cagcaccatc ggagtccacc      1440
     cgacgagcgc cgaggagctc tgctccatgc gcactccagc gtacttctac gagagtggca      1500
     agcgcgtcga aaagctcagc agcaacctct gaagagggag gagagatgaa gaagaacgcc      1560
     tcaagccctt ccacctagcc gtgatgcacg gtatcacaga ccagcaggca tgcgagagat      1620
     ggaaagggga agaggtcagc aggcagtgag ctctgat                               1657
//