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EBI DbfetchID Z22934; SV 1; linear; genomic DNA; STD; INV; 2271 BP. XX AC Z22934; XX DT 14-JUN-1993 (Rel. 36, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 11) XX DE S.mansoni ER-luminal cysteine protease ER 60 gene. XX KW form I phosphoinositide-specific phospholipase C. XX OS Schistosoma mansoni OC Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea; Strigeidida; OC Schistosomatoidea; Schistosomatidae; Schistosoma. XX RN [1] RP 1-2271 RX DOI; 10.1006/expr.1996.4123 RX PUBMED; 9149235. RA Finken-Eigen M., Kunz W.; RT "Schistosoma mansoni: gene structure and localization of a homologue to RT cysteine protease ER 60"; RL Exp. Parasitol. 86(1):1-7(1997). XX RN [2] RP 1-2271 RA Kunz W.; RT ; RL Submitted (04-JUN-1993) to the EMBL/GenBank/DDBJ databases. RL Kunz W., University of Duesseldorf, Institute of Genetics, RL Universitaetsstrasse 1, Duesseldorf, Germany, D-40225 XX FH Key Location/Qualifiers FH FT source 1..2271 FT /organism="Schistosoma mansoni" FT /strain="Liberia" FT /mol_type="genomic DNA" FT /dev_stage="adult" FT /clone_lib="genomic EMBL3-library of P.T. LoVerde" FT /clone="gN11-1" FT /db_xref="taxon:6183" FT 5'UTR 388..520 FT exon 388..654 FT /label=ex1 FT mRNA join(388..654,695..900,933..1161,1196..1309,1344..1640, FT 1675..2271) FT precursor_RNA 388..2271 FT sig_peptide 521..562 FT CDS join(521..654,695..900,933..1161,1196..1309,1344..1640, FT 1675..2149) FT /product="ER-luminal cysteine protease ER 60" FT /db_xref="GOA:P38658" FT /db_xref="HSSP:1MEK" FT /db_xref="InterPro:IPR012335" FT /db_xref="UniProtKB/Swiss-Prot:P38658" FT /protein_id="CAA80521.1" FT /translation="MRWLLSCLFLVAFASCSKVLELTKDNFHSELKSIPVALVKFYAPW FT CGHCKKLAPEFTSAAQIISGKTNDVKLVKVDCTTQESICSEFGVSGYPTLKIFRNGDLD FT GEYNGPRNANGIANYMISRAGPVSKEVSTVSDVENVLSDDKPTVFAFVKSSSDPLIKTF FT MALAKSMVDDAVFCHSHNNLFVTPSDNELRVYLPKRLRTKFEDDFAVYKGELESNNIKD FT WIRKHGQGLVGYRSPSNTFYFENSDLVVLYNNQSIDSYPSGVKYLRNRVLKTLKDNPQK FT FKNLVFAYSFADDFSYEISDYGIEADKLPAVVIQSKDKKYKLEKFSLDAFSDFLNKFED FT GLLTPHVKSEPLPTDDSSAVKKLVALNFDEIVNNEEKDVMVVFHAGWCGHCKNLMPKYE FT EAASKVKNEPNLVLAAMDATANDVPSPYQVRGFPTIYFVPKGKKSSPVSYEGGRDTNDI FT IKYLAREATEELIGYDRSGNPKKSEL" FT mat_peptide join(563..654,695..900,933..1161,1196..1309,1344..1640, FT 1675..2146) FT misc_feature 575..863 FT /standard_name="first thioredoxin domain" FT intron 655..694 FT exon 695..900 FT /label=ex2 FT intron 901..932 FT exon 933..1161 FT /label=ex3 FT intron 1162..1195 FT exon 1196..1309 FT /label=ex4 FT intron 1310..1343 FT exon 1344..1640 FT /label=ex5 FT intron 1641..1674 FT exon 1675..2271 FT /label=ex6 FT misc_feature 1778..2017 FT /standard_name="second thioredoxin domain" FT 3'UTR 2150..2271 FT polyA_signal 2254 FT polyA_site 2271 XX SQ Sequence 2271 BP; 705 A; 419 C; 418 G; 729 T; 0 other; caaagttaga gatatcaaca aatgtgaaac ttatagtgat caagttacga ccagtgccat 60 gaaaagtttt cagtagacgc tcaactccca aaccaacagc ctggatttca taagaacctg 120 tcattcaacg aagaaaatgc ttaaatggct tattaccctt tatgtaccat ttcataagct 180 ttttcttcag gttgcattcg acattgcatt gttttcaaac atcactataa attcaagaat 240 cctcatttag tctggactca taaattattc ataactatca gaatctgatt ttgttactcg 300 gagtgaccac tgttagccag ctctgaagaa ccacatcacg aactttcttt gtatattttt 360 ttttagttga attcatgaat cgatctaagc tagatcacca ttggaaccct caatctgaca 420 attactgttt tgtttatatc tattcgtcaa ccaaccaatc acataataac acatatctgg 480 cgtcgtataa agctgcacgt ttgagtgtta atccttaagg atgcgttggt tgctgtcgtg 540 tcttttcctc gtcgcatttg cgtcgtgtag caaggtcctt gagctcacta aagacaattt 600 ccattctgaa ttaaagtcca taccagttgc tctggtgaag ttttacgctc catggtaatt 660 tcgagtggtt ttattaaaac ttgatattaa acaggtgtgg acactgtaaa aaactagctc 720 ctgagttcac ttcagccgca caaattatat ccggaaaaac taacgatgtt aagctcgtta 780 aggttgattg tactactcaa gaaagtatct gctcggagtt cggagttagt ggctacccta 840 ctctgaaaat cttcaggaat ggagatttag acggtgaata taatggtcca agaaatgcaa 900 gtaagattca tgttattata actcaggtgc agatggaatc gccaattata tgatatcccg 960 agcaggacct gtatccaaag aagtcagcac tgttagtgat gtagagaacg tcttgtcaga 1020 cgacaagcca actgtgtttg cttttgtaaa atcgtctagc gacccgttaa taaaaacatt 1080 catggctctt gcaaaatcaa tggttgacga tgctgtattt tgtcatagtc ataataatct 1140 ttttgtaact cctagtgaca agtaagttat tgattgctta ataaccattt ttcagcgagt 1200 tgagagtcta cttgcctaaa cgtcttcgaa cgaagtttga ggatgacttc gctgtttata 1260 aaggagaact tgaatctaac aatattaaag actggattcg caaacatggg taaggaagtt 1320 gtcctgtctt attttcaatt tagccaggga ctggttggtt atagatcacc gtcaaataca 1380 ttttacttcg aaaattccga tttagtagta ttatacaata accaatccat agattcatat 1440 ccatctggag taaaatacct aagaaatcgt gttctcaaaa cccttaagga caacccccaa 1500 aaattcaaga atttggtttt cgcttatagc tttgcggacg atttttctta tgaaatatct 1560 gattatggta tagaagcgga taagttacca gcggttgtaa tccaatctaa agacaaaaag 1620 tacaagcttg agaaatttag gtaagttttt tcgtaattaa ttatcttgtc atagtcttga 1680 tgccttctct gattttttga ataaatttga agatggtctt ttgaccccac atgtaaaatc 1740 agaacctctc ccaacagacg actctagtgc agtcaaaaag ttagttgcac tcaactttga 1800 tgagatagta aataacgagg agaaagatgt aatggtcgtc tttcatgctg gttggtgtgg 1860 tcattgtaaa aatctaatgc caaagtacga ggaagcagcc agtaaagtaa aaaatgaacc 1920 aaatttggtt ttggctgcta tggatgcaac cgccaatgat gtcccttcgc cttatcaagt 1980 caggggattc ccaactatct atttcgtccc taaaggaaag aaatcttcac ctgtatctta 2040 cgagggtggt cgagacacta atgacatcat caagtacctt gcacgcgaag ctactgaaga 2100 acttattggg tacgacagat caggcaatcc aaagaaaagt gaactatagg atgtctttaa 2160 taatcttatt tttcgaaaca ttgtattata tttcctcatt tttactgatt ctttgataaa 2220 tcataattgt gatgtatttc aacttttagt tggtaataaa cctgtttttt g 2271 // |
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