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EBI DbfetchID Z21490; SV 2; linear; genomic DNA; STD; VRL; 6495 BP. XX AC Z21490; M31715; XX DT 01-JUN-1993 (Rel. 36, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 9) XX DE African swine fever virus tdk, EP1242L, K145R, K421R and EP84R genes XX KW EP1242L gene; protein EP84R; protein K145R; protein K421R; KW RNA polymerase second largest subunit; tdk gene; thymidine kinase. XX OS African swine fever virus OC Viruses; dsDNA viruses, no RNA stage; Asfarviridae; Asfivirus. XX RN [1] RP 1-770 RA Bockamp E.-O.; RT ; RL Submitted (29-JAN-1990) to the EMBL/GenBank/DDBJ databases. RL Bockamp E.-O., YANEZ, Centro de Biologia Molecular (CSIC-UAM), Campus, de RL Cantoblanco, Madrid, 28049, SPAIN. XX RN [2] RP 1-761 RX DOI; 10.1016/0042-6822(90)90409-K RX PUBMED; 2389555. RA Blasco R., Lopez-Otin C., Munoz M., Bockamp E.-O., Simon-Mateo C., RA Vinuela E.; RT "Sequence and evolutionary relationships of African swine fever virus RT thymidine kinase"; RL Virology 178(1):301-304(1990). XX RN [3] RP 636-6495 RA Yanez R.J.; RT ; RL Submitted (22-JAN-1993) to the EMBL/GenBank/DDBJ databases. RL Rafael J. YANEZ, Centro de Biologia Molecular (CSIC-UAM), Campus, de RL Cantoblanco, Madrid, 28049, SPAIN. XX RN [4] RP 636-6495 RX DOI; 10.1093/nar/21.10.2423 RX PUBMED; 8506138. RA Yanez R.J., Boursnell M., Nogal M.L., Yuste L., Vinuela E.; RT "African swine fever virus encodes two genes which share significant RT homology with the two largest subunits of DNA-dependent RNA polymerases"; RL Nucleic Acids Res. 21(10):2423-2427(1993). XX FH Key Location/Qualifiers FH FT source 1..6495 FT /organism="African swine fever virus" FT /strain="BA71V" FT /mol_type="genomic DNA" FT /clone="p5RK" FT /clone="p5RY'" FT /clone="p5RE'" FT /db_xref="taxon:10497" FT CDS 61..651 FT /gene="tdk" FT /product="thymidine kinase" FT /EC_number="2.7.1.21" FT /db_xref="GOA:P18555" FT /db_xref="InterPro:IPR001267" FT /db_xref="InterPro:IPR020633" FT /db_xref="UniProtKB/Swiss-Prot:P18555" FT /protein_id="CAG33722.1" FT /translation="MNIIRKLKPGTISLVLGPMFAGKTTFLIHCIYMLERLEKKVVFIK FT STKNTRDKTIKTHSGIQLRPKQCKIIESTQLSDVGSLTDIHAVVVDEAHFFDDLIKCRT FT WAEEEKIIILAGLNASFEQKMFPPIVRIFPYCSWVKYIGRTCMKCNQHNACFNVRKNAD FT KTLILAGGSELYVTCCNNCLKNTFIKQLQPIKY" FT CDS complement(2421..6149) FT /gene="EP1242L" FT /product="putative RNA polymerase second largest subunit" FT /function="DNA-dependent RNA polymerase" FT /EC_number="2.7.7.6" FT /db_xref="GOA:P42487" FT /db_xref="InterPro:IPR007120" FT /db_xref="InterPro:IPR007121" FT /db_xref="InterPro:IPR007641" FT /db_xref="InterPro:IPR007642" FT /db_xref="InterPro:IPR007645" FT /db_xref="InterPro:IPR007646" FT /db_xref="InterPro:IPR007647" FT /db_xref="InterPro:IPR015712" FT /db_xref="UniProtKB/Swiss-Prot:P42487" FT /protein_id="CAA79698.1" FT /translation="MEPLRPQITYGPIETVDNEELTEADMLSFISAAVNSTGLIGYNIK FT SFDDLMDNGIPQIVKQMFNVDITYKDQRDHTEIDKLRESVQIQFNFTDVNIERPQHRNY FT SQGNKINLLPNKARLCGLSYSGPVNLAAEVILTAHYSNGRQEVKRASIPPFQVSTFPIM FT RGSNRCHTHHLSKTAKKEIGEDPNEPGGYFIARGGEWVVDLLENIRFNTLHIHYHTMQQ FT GNNEIIRGEFISQPGGAFENSSQIIIRYMTTGAITIEINSTKFSKLRIPWYLIFRMFGM FT TGDDSIIEQVVFDLESNSPVNTFMIEILEKSIHVLDPIFQPVQHEPNREKIIQFLSEKV FT SKFVSNPSAYKSDENAVQYLNERQLTILDKILLPHMGQTADTRVRKLRFLGLLIHKILL FT VIMNVFPPTDRDSYRTKRVHGSGVSLAKAFKAIFNTSVIAPIINGFKELLKQTAFEELT FT QRNIIEAFSAALSKNTASDLNRSMEQSIISGNKTIMVRQRPIVNRVSTQSLERKNLLNT FT ISALRTVNTHNTTNASKQTERADMMRRVHASYPGYICVAQSADTGEKVGMSKQLAITAN FT VCTAGEVLSLKQRLLSDPAIQQLADVSNKDIVRKGLARVFINGEWIGCCTNAFELAQRY FT RMFRREGKIVHPHTTIYWDSMVDEVEFWLDVGRLTRPLLIVDNNIEKYNQACYKAAEAR FT KKGDKDWEKHKIPFIQNTRFTSQMAKDILAGTLTLEDLVAQGICEFITPEEAENCLVAF FT SIIELRKHKHDVTRRFTHVDVPQAILGLAALVSPYANCTQPARVTYETNQGRQTGGWYC FT FSWPYRVDMNRFFQFYNEMPLVKTIAHNYVIPNGLNTIVAYMIYGGYNQEDSVIVSQSF FT IDRGGFAGTFYREEKVELESDIESFGKPDPLITKNLKPGANYEKLVDGFVPVGTVVKKG FT DIIIGKVAKIRGEKDELNKYIDRSVMYGFDEPAVVDAVMRPHGPNDEIFGLMRLRYERN FT LNIGDKMSSRSGNKGIAALALPTSDMPFTEDGLQPDLIVNPHSHPSRMTNGQMIETTVG FT LANALQGVVTDGTAFLPINVQLLSERLAQEGLRFNGCQKMFNGQTGEYFDAAIFIGPTY FT HQRLQKFVLDDRYAVASYGPTDALTGQPLDGKRSHGGLRLGEMEHWVLTAQGAMQTIIE FT KSHDDSDGCISYICRNCGEPAIYNASHPIYKCMNCDVQADIGMVDSRRSSIVFQHEMRA FT ANVNITSVLSPRVFQPA" FT CDS 667..1104 FT /gene="K145R" FT /product="protein K145R" FT /note="putative" FT /db_xref="UniProtKB/Swiss-Prot:Q07385" FT /protein_id="CAA79699.1" FT /translation="MDHYLKKLQDIYTKLEGHPFLFSPSKTNEKEFITLLNQALASTQL FT YRSIQQLFLTMYKLDPIGFINYIKTSKQEYLCLLINPKLVTKFLKITSFKIYINFRLKT FT FYISPNKYNNFYTAPSEEKTNHLLKEEKTWAKIVEEGGEES" FT CDS 1137..2402 FT /gene="K421R" FT /product="protein K421R" FT /note="putative" FT /db_xref="UniProtKB/Swiss-Prot:Q07384" FT /protein_id="CAA79700.1" FT /translation="MYTHVDVVGIAEASAALYVQKDRDRYLDVLTTIENFIYQHKCIIT FT GESAHLLFLKKNIYLYEFYSNNVAEHSKALATLLYKLDPEYLTRYTVLITKIPNHWYVI FT NVDQREFVRLYAIPAVKQHLPIPILPFYCTSALTHQELFCLGPELQLIQIYSKLCNPNF FT VEEWPTLLDYEKSMRMLFLEQFPRRLEIAGGKKEEEKHESIIKKIILEMVSTRQRIVVG FT GYIQKNLYNHVLKNRNRLQLITSLDIYEEKDIIQQFCDSNGLKIKIRINNPLLPTNPEL FT RRLTIYFNHNNDDDQSYLIVDMYNTGSYELVPTNQINTLDGSFLIGTPFVQARFLLVEI FT WVLMLIAQQTKKDTKKIIQFFINQYEMLMNSPWPSMEALFPSSSKRYLGNYVDPNALIK FT WAQLKLKRIPPFYPGKPDEESC" FT CDS 6228..6482 FT /gene="EP84R" FT /product="protein EP84R" FT /note="putative" FT /db_xref="GOA:Q07383" FT /db_xref="UniProtKB/Swiss-Prot:Q07383" FT /protein_id="CAA79701.1" FT /translation="MPYSRDITKFITATEPEVGLPLLALQHSKSVIGVILLVISLLFIF FT IGIIILSVSSGHTTAASIFIVLSLILGGGGFFLIYKDNS" FT old_sequence 697..737 FT /replace="" FT /note="this sequence corrects entry M31715, in which FT nucleotides 697..737 are missing" FT /citation=[3] FT repeat_region 2379..2435 FT /rpt_unit_range=2379..2400 FT /note="there are 3 repeat units, last one being a truncated FT form with only 13 bp" FT /citation=[1] XX SQ Sequence 6495 BP; 1810 A; 1364 C; 1417 G; 1904 T; 0 other; ttaccagaat ggatcgcgtc ttactaaaag tgaattggag aaaaaaatta aacggtcaaa 60 atgaatataa ttaggaagct taagcctgga acaattagcc ttgtgctggg acccatgttt 120 gccggcaaaa ctacgtttct tattcattgc atttacatgc tcgaacgttt ggaaaaaaaa 180 gtagtcttca taaaatctac caaaaacacc cgagacaaaa ctattaaaac acactccggt 240 atacagctac gacccaagca atgtaaaatc atagaaagca cacagttatc tgacgtggga 300 tctctcaccg atatccatgc agttgtcgta gatgaagcgc atttttttga cgatttaata 360 aaatgccgca cctgggcaga ggaagaaaaa attattattc ttgcgggact caatgcttcc 420 ttcgagcaga aaatgtttcc gcccatcgtt cgtatttttc cttactgcag ctgggttaag 480 tatattggcc gcacctgtat gaaatgtaac caacataatg catgctttaa tgtgcgtaag 540 aacgcagaca agacgcttat ccttgcggga ggaagtgaac tgtacgtaac atgttgtaac 600 aactgtctaa aaaatacatt tattaagcag ttgcaaccta ttaaatatta aaaatcttat 660 acaataatgg atcattatct taaaaaatta caagatattt atacgaagct cgagggccat 720 ccctttcttt ttagcccgtc gaaaaccaat gaaaaagagt ttattactct gctaaaccag 780 gccttggcct caacgcagct ttaccgcagc atacaacagc tgtttttaac gatgtataag 840 ctagatccca ttgggtttat taactatatt aaaacgagta aacaagagta tttatgcctg 900 ttgattaatc ctaaactcgt tactaagttt ttaaaaataa cgagctttaa aatttacatt 960 aatttcagac tgaaaacttt ttatataagt cctaataagt ataataattt ttacactgct 1020 ccctctgaag aaaagactaa ccatctccta aaagaagaaa aaacttgggc aaagattgtt 1080 gaagaaggag gagaagaatc ctaagtcgct tacatttttt tttgccattt tatagaatgt 1140 acacgcatgt tgatgttgtc ggaatagctg aagcctcagc ggccctctac gtgcaaaaag 1200 atagggatcg ctacttggac gtgctaacaa ccatcgaaaa ctttatttac caacacaaat 1260 gcatcataac aggggaaagc gcccacctac tctttttaaa aaaaaatatt tatctttacg 1320 aattttactc caacaatgtg gcggagcaca gcaaggcttt ggcgaccctg ctttacaaac 1380 ttgatccgga atacctcact cgttacacag tactcatcac caagattccc aaccattggt 1440 atgtgattaa cgttgatcag cgagaatttg tgcgcctata tgccattccg gcagttaaac 1500 aacacttacc gattcccatt ttacccttct attgcaccag cgcactcacc caccaagaat 1560 tgttttgttt aggacctgaa ctgcagttaa tacaaatata ttccaagctc tgtaacccca 1620 actttgtcga ggaatggcct acgttgctcg actacgaaaa aagcatgcgg atgttatttt 1680 tagaacagtt tccgcgaaga ttggaaatag cgggcgggaa gaaggaggag gaaaagcatg 1740 aaagtatcat taaaaaaata atactagaaa tggtctctac ccgtcagcga atcgttgttg 1800 gaggttacat acaaaaaaac ctgtacaacc atgtactcaa gaatagaaat cgtttacagc 1860 ttattacgag cttagatatt tatgaagaaa aagatatcat ccagcaattt tgtgattcaa 1920 atggactgaa gatcaaaata cgtatcaaca atccgctctt gcctacaaat ccggaattac 1980 ggcgtttgac tatttatttt aatcataata atgatgatga tcagtcatat ctaatagtag 2040 atatgtacaa cacgggaagc tatgagctag tgcctacaaa tcagataaac acgcttgatg 2100 gcagtttttt aataggaaca cccttcgtgc aagcgcgatt tttgttggta gagatctggg 2160 tgcttatgct tattgcgcag caaactaaaa aggacaccaa aaaaataata caatttttta 2220 taaatcaata tgaaatgctt atgaatagtc cttggcccag tatggaggcc ctttttccct 2280 caagcagtaa aagatattta ggcaactatg tagaccctaa cgcgctcata aagtgggcac 2340 aactcaaatt aaaaagaata ccgccttttt atcccggaaa gccggatgaa gaatcatgtt 2400 aagccgattg aaaaatcatg ttaagccggt tgaaatactc ttggtgaaag cacggatgta 2460 atattaacat tggccgcccg catttcgtgt tgaaatacga tggaggagcg acggctatct 2520 accatgccga tatcggcctg gacatcacag ttcatgcact tgtagatggg atgactcgcg 2580 ttatagatgg caggctcgcc acagtttcta cagatgtagg agatgcagcc atccgagtcg 2640 tcgtgcgatt tttctatgat ggtttgcatg gcgccctgcg ccgtaagcac ccaatgctcc 2700 atttctccca gacgaagacc tccgtgcgat cgtttgccgt ccaacggctg gcctgtgagg 2760 gcatccgtgg gcccatagct tgcaacggcg tatcggtcat ccagcacaaa tttttgcagg 2820 cgctggtgat aggtcggtcc tatgaagatg gccgcatcaa agtactcgcc ggtctggccg 2880 ttgaacattt tttggcatcc attgaagcgt agaccttctt gcgccagtct ttctgaaaga 2940 agctgcacgt taataggcag gaatgcggtg ccgtctgtta ccaccccctg tagggcattt 3000 gctagaccaa ccgtggtttc tatcatttga ccgttggtca ttcgggaggg atgtgagtgg 3060 gggtttacaa tgagatcggg ctgcagtccg tcctctgtga agggcatgtc tgaggtgggc 3120 agggccagcg ccgcaatgcc cttgttcccg ctgcgagaac tcatcttgtc gcctatattg 3180 agatttcttt catagcgcag gcgcatgagg ccaaagatct cgtcattggg cccatgggga 3240 cgcatcacag catccacgac ggccggctca tcgaagccgt acatgacaga ccggtcgatg 3300 tatttgttga gttcgtcttt ttcgccccgt attttggcca cttttcctat aatgatgtcg 3360 ccctttttga ccaccgttcc cacgggcaca aacccatcta caagcttttc gtaattagca 3420 cccggcttaa gatttttggt gattaaaggg tcgggcttcc caaacgactc tatatcgctt 3480 tctaattcta ctttttcttc tcggtagaag gtgccggcaa agccgcccct gtcaataaag 3540 gactgcgaca cgatcacaga gtcctcctga ttgtagccgc cgtagatcat ataggccaca 3600 atggtattaa gcccgttggg tatgacatag ttatgtgcta tggtctttac aagcggcatt 3660 tcattgtaaa actggaagaa acggttcatg tctacacgat atggccagct gaagcagtac 3720 caaccccccg tctgcctacc ctgatttgtt tcataagtaa cacgagcagg ttgggtacag 3780 tttgcgtagg gggacactag ggcggcaagg cccaaaatag cttggggcac gtccacgtgt 3840 gtgaaacgac gtgttacatc atgtttgtgc ttgcgtagct cgatgataga gaaggcaaca 3900 agacagtttt ccgcttcttc gggggtaatg aattcacaga tgccctgcgc tacgagatct 3960 tcaagtgtaa gtgttccggc taaaatgtct tttgccattt gagacgtaaa tcgcgtattt 4020 tgaatgaaag ggattttatg tttttcccag tctttatcgc ctttttttct ggcctctgcg 4080 gccttgtaac aggcttgatt gtatttttca atattattat ctacaatgag cagggggcgg 4140 gtcagcctac cgacgtccaa ccagaattct acttcgtcta ccatgctatc ccagtagatg 4200 gtggtatggg gatgcacaat cttgccctca cggcgaaaca ttctataccg ctgagcaagc 4260 tcaaaggcgt tggtgcagca gccaatccat tctccgttga taaatacgcg cgctaggccc 4320 tttcgtacaa tgtccttgtt ggaaacatcg gctaactgtt gaatggccgg atctgataga 4380 aggcgttgtt ttaacgaaag tacttctcca gcggtacaga cattggcggt aatggctaac 4440 tgtttagaca tacctacttt ttcaccagta tcggctgact gggctacgca gatgtatcca 4500 ggataagatg cgtgcacgcg acgcatcatg tcagcccttt ctgtttgttt ggatgcgttg 4560 gtggtgttat gagtatttac cgtacgcaac gctgaaatcg tatttaataa attttttctt 4620 tccaaacttt gagtagatac tctgtttaca atggggcgct gtcgcaccat gatggtttta 4680 tttcctgaaa tgatagactg ttccatactg cgattgagat cggaggcggt attttttgat 4740 aaagcggcag aaaatgcctc gataatgttt cgctgggtta gctcctcaaa agctgtttgt 4800 ttaagaagtt ctttgaaccc attgatgatg ggtgctatca cggatgtatt aaaaatagcc 4860 ttaaaggcct tagcaagcga gacccctgag ccgtgcaccc gcttggtgcg gtagctatca 4920 cggtccgtgg gtggaaacac attcataatg acaagaagta ttttatgaat aagcaggcct 4980 aaaaagcgca gttttcgtac acgtgtatct gcggtttggc ccatgtgtgg caacaatatt 5040 ttgtctaaaa tagtaagttg tctttcattc aagtattgta ccgcattttc atcgcttttg 5100 taagcagatg ggtttgagac aaatttggaa accttctcag ataaaaactg gataattttt 5160 tctcggttcg gctcgtgttg gaccggttga aatatggggt ctaaaacatg aatggatttt 5220 tccagaattt ctatcatgaa ggtattcaca ggggagttgg attccagatc gaataccact 5280 tgctcaatga tgctgtcatc gcctgtcatt ccaaacatgc gaaagatgag ataccaaggt 5340 atgcgaagtt ttgagaactt ggtgctattg atttcaatgg taatggcacc agtagtcatg 5400 tagcgtataa taatttgaga gctattttcg aaggcacctc ctggttgaga gataaactcg 5460 ccgcgaatga tttcattatt cccttgttgc atggtatggt aatggatgtg aagcgtgtta 5520 aagcggatgt tttctaagag gtctacgacc cattccccgc ctcgggctat aaagtagccg 5580 ccgggttcat tagggtcttc tcctatttct ttttttgcgg tttttgatag gtgatgagtg 5640 tggcagcggt tgctgccccg catgatggga aatgtggaca cctgaaatgg aggaatactt 5700 gctcgtttta cctcctgccg accattgctg tagtgcgccg ttaaaataac ctcggcggct 5760 agattaacag ggcccgaata ggaaaggcca cacaggcgtg ccttattagg tagtaaattt 5820 atcttgtttc cctgtgaata gtttcgatgt tgcgggcgtt caatgttcac atctgtaaag 5880 ttaaattgga tctgaaccga ttcccgaagc ttatctattt cagtatggtc gcgttggtct 5940 ttataagtaa tatccacgtt aaacatttgt tttacaattt gcgggattcc attgtccata 6000 agatcgtcga agcttttgat gttataccct atcaatcctg tagagtttac tgcagcggag 6060 ataaagctca gcatatcagc ctctgtaagc tcctcattat ccacggtttc aatggggccg 6120 taggttattt gcggccgcaa gggttccata attatgaagt actacattaa tattcagtta 6180 ttctttaaaa taaatcttta tttataaatc ttatttataa tataagaatg ccttattcaa 6240 gagatatcac aaagtttatc acggcaacgg aaccagaggt gggtctcccc ctgttggcgc 6300 tgcaacactc caagtccgtc ataggggtta ttcttcttgt aataagtttg ttatttattt 6360 tcattggcat tattatacta tcggtgagta gtggtcatac cacagcagcc tctatattta 6420 tcgtattgag tcttatccta ggtggcggtg gtttttttct tatttataaa gataattctt 6480 aacccacata aaatt 6495 // |
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