EBI Dbfetch

ID   Y18523; SV 4; linear; genomic DNA; STD; PRO; 41323 BP.
XX
AC   Y18523; AJ293724;
XX
DT   16-DEC-1998 (Rel. 58, Created)
DT   06-MAR-2006 (Rel. 87, Last updated, Version 7)
XX
DE   Actinoplanes sp. SE50/110 complete acarbose (acb) gene cluster, strain
DE   SE50/110
XX
KW   1-epi-valienol-1,7-bisphosphate-1-adenylyltransferase AcbR;
KW   2-epi-5-epi-valiolone 7-kinase AcbM; 2-epi-5-epi-valiolone synthase AcbC;
KW   2-epi-5-epi-valiolone-7-phosphate 2-epimerase AcbO;
KW   ABC transporter ATP-binding protein AcbW;
KW   ABC transporter binding protein AcbH;
KW   ABC transporter membrane protein AcbF;
KW   ABC transporter membrane protein AcbG;
KW   ABC transporter permease protein AcbX;
KW   ABC transporter permease protein AcbY;
KW   acarbose 4-alpha-glucanotransferase AcbQ; acarbose 7-kinase AcbK;
KW   acarbose resistent alpha-amylase AcbE; acarviose transferase (ATase) AcbD;
KW   acbA gene; acbB gene; acbC gene; acbD gene; acbE gene; acbF gene;
KW   acbG gene; AcbH gene; acbI gene; acbJ gene; acbK gene; acbL gene;
KW   acbM gene; acbN gene; acbO gene; acbP gene; acbQ gene; acbR gene;
KW   acbS gene; acbU gene; acbV gene; acbW gene; acbX gene; acbY gene;
KW   acbZ gene; alpha-amylase AcbZ; asp.3.3 gene; asp3.1 gene; asp3.2 gene;
KW   cyclitol dehydrogenase AcbL; cyclitol oxidoreductase AcbN;
KW   dTDP-4-keto-6-deoxy-glucose 4-aminotransferase AcbV;
KW   dTDP-glucose 4,6-dehydratase AcbB; dTDP-glucose synthase AcbA;
KW   galactocerebrosidase; glycosyltransferase AcbI; glycosyltransferase AcbS;
KW   hydrolase AcbJ; kinase (1-epi-valienol-7-phosphate 1-kinase) AcbU;
KW   NUDIX hydrolase AcbP; xylanase.
XX
OS   Actinoplanes sp. SE50/110
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Micromonosporineae; Micromonosporaceae; Actinoplanes.
XX
RN   [1]
RX   DOI; 10.1074/jbc.274.16.10889
RX   PUBMED; 10196166.
RA   Stratmann A., Mahmud T., Lee S., Distler J., Floss H.G., Piepersberg W.;
RT   "The AcbC protein from Actinoplanes species is a C7-cyclitol synthase
RT   related to 3-dehydroquinate synthases and is involved in the biosynthesis
RT   of the alpha-glucosidase inhibitor acarbose";
RL   J. Biol. Chem. 274(16):10889-10896(1999).
XX
RN   [2]
RC   Revised by [3]
RA   Piepersberg W.;
RT   ;
RL   Submitted (09-DEC-1998) to the EMBL/GenBank/DDBJ databases.
RL   W. Piepersberg, Bergische Universitaet Wuppertal, Gesamthochschule,
RL   Institut fuer Chemische Mikrobiologie, Gaussstr. 20, 42097 Wuppertal,
RL   GERMANY.
XX
RN   [3]
RC   revised by [4]
RA   Stratmann A.;
RT   ;
RL   Submitted (06-NOV-2000) to the EMBL/GenBank/DDBJ databases.
RL   A. Stratmann, Bergische Universitaet Wuppertal, Gesamthochschule, Institut
RL   fuer Chemische Mikrobiologie, Gaussstr. 20, 42097 Wuppertal, GERMANY.
XX
RN   [4]
RC   revised by [11]
RA   Piepersberg W.;
RT   ;
RL   Submitted (04-APR-2002) to the EMBL/GenBank/DDBJ databases.
RL   Piepersberg W., Bergische Universitaet Wuppertal, Gesamthochschule,
RL   Institut fuer Chemische Mikrobiologie, Gaussstr. 20, 42097 Wuppertal,
RL   GERMANY.
XX
RN   [5]
RP   28225-34203
RA   Stratmann A.;
RT   ;
RL   Submitted (04-AUG-2000) to the EMBL/GenBank/DDBJ databases.
RL   Stratmann A., Chemische Mikrobiologie, BUGH Wuppertal, Gaussstr. 20, 42097
RL   Wuppertal, GERMANY.
XX
RN   [6]
RX   DOI; 10.1128/JB.183.15.4484-4492.2001
RX   PUBMED; 11443082.
RA   Hemker M., Stratmann A., Goeke K., Schroeder W., Lenz J., Piepersberg W.,
RA   Pape H.;
RT   "Identification, cloning, expression, and characterization of the
RT   extracellular acarbose-modifying glycosyltransferase, AcbD, from
RT   Actinoplanes sp. strain SE50";
RL   J. Bacteriol. 183(15):4484-4492(2001).
XX
RN   [7]
RX   DOI; 10.1074/jbc.M202375200
RX   PUBMED; 11937512.
RA   Zhang C., Stratmann A., Block O., Brueckner R., Podeschwa M.,
RA   Altenbach H.J., Wehmeier U.F., Piepersberg W.;
RT   "Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes
RT   species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor
RT   leads to proposal of a new biosynthetic pathway";
RL   J. Biol. Chem. 277(25):22853-22862(2002).
XX
RN   [8]
RX   DOI; 10.1016/S0014-5793(03)00221-7
RX   PUBMED; 12681481.
RA   Zhang C., Podeschwa M., Altenbach H.J., Piepersberg W., Wehmeier U.F.;
RT   "The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a
RT   2-epi-5-epi-valiolone-7-phosphate 2-epimerase";
RL   FEBS Lett. 540(1-3):47-52(2003).
XX
RN   [9]
RX   DOI; 10.1016/j.resmic.2004.10.016
RX   PUBMED; 15808935.
RA   Brunkhorst C., Wehmeier U.F., Piepersberg W., Schneider E.;
RT   "The acbH gene of Actinoplanes sp. encodes a solute receptor with binding
RT   activities for acarbose and longer homologs";
RL   Res. Microbiol. 156(3):322-327(2005).
XX
RN   [10]
RA   Wehmeier U.F., Thomas H., Diaz-Guardamino Uribe P.M., Zhang C., Rockser Y.,
RA   Piepersberg W.;
RT   "The acb-gene cluster for acarbose biosynthesis from Actinoplanes sp.
RT   SE50/110: functional analysis and heterologous expression in
RT   streptomycetes";
RL   Unpublished.
XX
RN   [11]
RP   1-41323
RA   Wehmeier U.F.;
RT   ;
RL   Submitted (10-JAN-2006) to the EMBL/GenBank/DDBJ databases.
RL   Wehmeier U.F., Bergische Universitaet Wuppertal, Gesamthochschule, Institut
RL   fuer Chemische Mikrobiologie, Gaussstr. 20, 42097 Wuppertal, GERMANY.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..41323
FT                   /organism="Actinoplanes sp. SE50/110"
FT                   /strain="SE50/110"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:134676"
FT   CDS             complement(<1..1206)
FT                   /transl_table=11
FT                   /gene="asp.3.3"
FT                   /product="hypothetical protein"
FT                   /db_xref="InterPro:IPR001633"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS9"
FT                   /protein_id="CAJ81017.1"
FT                   /translation="MIQRNRQVCDARNESVALISRVVAERAVEPLFQPIVDLDTRRLVG
FT                   AEALARGPAGSPLEFPDQLFEAAARVDLVPELDQLCAARAHEIAQAPGAVVPPLVFINK
FT                   EPAGADRPLSEDLRLRLASISTYRYVLEFTERALAAHPSALLEVAARAHRTGGALALDD
FT                   VGADRLSLAFLPLLEPEVVKLDMHLLRDPYCAHTIETTALVCGYAQRTGAMVIAEGIET
FT                   EQDLQVARALGAGWGQGWLFARPGPLSAVRDWPVDPSARLRAPRPELYVPGASPFDMAS
FT                   ARHRARTGDRHLLDGLTAHVLRQLPFAGPYGVVLGAYPDLATGHGWIPRLADAASTAAL
FT                   VGVSGPGPGLPAPSPIRTSITDGLSGVESEAALVIVDPHVTVALCTRRRHDDAIDFVLT
FT                   FDP"
FT   CDS             1728..5039
FT                   /transl_table=11
FT                   /gene="acbZ"
FT                   /product="alpha-amylase AcbZ"
FT                   /function="secreted alpha-amylase is involved in starch
FT                   degradation"
FT                   /db_xref="GOA:Q27GS8"
FT                   /db_xref="InterPro:IPR013781"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS8"
FT                   /protein_id="CAJ81018.1"
FT                   /translation="MKRRPLRTAGAPAGTAPRSPSRPEEGRVLVLSRHRDVMRRLSAVL
FT                   ALGLVVPLLLAPPWRASAAPAGAAEPSAAALAHWGADRPAPAEQFYFVLPDRFADGNPK
FT                   NDTGGLSGDRLSTGYDPTDKGFYHGGDIQGVIDKLDYIQGLGTTAIWLAPVFKNRPVQG
FT                   TGAAASAGYHGYWVTDFTQVDPHFGTNADLKRLVQLAHRRGLKIYLDIIVNHTADVIQN
FT                   EGGKSTYVDKADAPYRDSRGRPFEDHNYADGSRPFPKVNLQSFPYTPVFASPADATAKV
FT                   PAWLNDPTMYHNRGNSLFSGENSEYGDHTGLDDLWTERPEVVRGMTEIYADWIRDADID
FT                   GYRMDTVKHSNIEFWQQFNPAIQQAARRAGKPGFFMFGEVFSADQEVESRYVRQGGLAA
FT                   SLDFSFQSAARTFVSGDTPATALADLYRHDDLYTARDTGAGRMPTFLGNHDIGRIGSFI
FT                   TTGGADRTSYLRRDQLAHELMFLTRGQPVVYSGDEQGFTGPGGDKDARQDMFASRTPDY
FT                   LDDDLIGTDRTHASDNYDTGHPLYRTIAELGALRKANPALRDGVQITRYAAPGAGIFAF
FT                   SRVDPVRRQEYLVAVNNATTAQTATVGTATPGSTFTGVYRAGGTAATGSDGKLTVTVPA
FT                   LSAVVYRGGSPIAVPSARPTVRISAPAAGASVPSRADLVADVTGDPLATVTFAAQAGSG
FT                   PWTVIGTARQAPYQVHHDLTGLAGGVTVRYKAVVRDGRGRTASSTSSLRVGTPDTHVAP
FT                   ERMVVHYQRPAGDYGAWRLYAFGDIDASAQTTYPDGQPFAGQDEYGAFAWVRLKPGAKN
FT                   AGFVVVDGNGVKDVQQDRFVDPGRQPEIWLKAGDATVYPSRQDATGRPDPQPDPKTAVL
FT                   HYRRADGDYTGWGLHVWDGAAQPTEWTAPLAPSGRDAYGVTFRVPLADGATGVSYVLHA
FT                   GDTKDQPTDQRIDFAAGREVWLLDGVAERLLPVTRRTAAGAGIDVTTSRAGWASRDTVV
FT                   WNTGVGSTLQPVGGGTDGRVYELAYAPVGGITVVGGELAGAYRTLRLTAQRDGLTESQR
FT                   VRFPKLWRYGAFRVADADRHRLATALRGQVVITERDASGKLLAATGVGAAGDLTG"
FT   CDS             complement(5104..5907)
FT                   /transl_table=11
FT                   /gene="acbY"
FT                   /product="ABC transporter permease protein AcbY"
FT                   /function="acarbose export"
FT                   /db_xref="InterPro:IPR010390"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS7"
FT                   /protein_id="CAJ81019.1"
FT                   /translation="MTVSTARRYLRLTAVLCGASLHRLTAYRMDFLIGAASFVIRIACQ
FT                   IALIGVIFQYVPALGGWTRQQALFLLGFSLLPRGLDRLFTDQLWILAWQLVRTGDFFRY
FT                   LIRPVNPFYALLSERFLYPDGFGELATGIAIVVTAAGTMDLHLTVAQWLLLLPLVLGGA
FT                   LIHTFLKAFLASLSFWMTSSLNVMVAVNQLSEFTAYPLNLYHPVLRGVLTWVLPFAFTA
FT                   YLPVRYLLTGDAGPLLWMLPVTTLTVLLGYGTFRLGLRRYEMPGS"
FT   CDS             complement(5904..6707)
FT                   /transl_table=11
FT                   /gene="acbX"
FT                   /product="ABC transporter permease protein AcbX"
FT                   /function="acarbose export"
FT                   /db_xref="InterPro:IPR010390"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS6"
FT                   /protein_id="CAJ81020.1"
FT                   /translation="MIRAARRYAPFALAGLHAVTRYRSTIVLSALTAAAATSLQVFLWR
FT                   AVYAGGPAPAGLPFAQLTSYIVLAQVLGMLHTNRIDEMIAGEVYRGDIAVSLVRPANYA
FT                   LSCLAVNLPTAALSALLAGAPVLAGFAMFASLPAPPPANLLLFAVALLLSVILAFEINF
FT                   LVGLAAFVTTNTWGIRTIKNALVAFLAGQVVPLALFPDGVARLLRLLPFQGLIDSPLRL
FT                   LLGGYSGGSGAAAILGVQALWAVLLYGVLALAWNRSLRRVEVLGG"
FT   CDS             complement(6704..7777)
FT                   /transl_table=11
FT                   /gene="acbW"
FT                   /product="ABC transporter ATP-binding protein AcbW"
FT                   /function="acarbose export"
FT                   /db_xref="GOA:Q27GS5"
FT                   /db_xref="InterPro:IPR003593"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS5"
FT                   /protein_id="CAJ81021.1"
FT                   /translation="MPGYARHARPDGTTGMIVAEHLSKHFKRYRREPGLRGSLRTMFSA
FT                   RYDVVRAVDDISFEVPSGVKIAYIGANGAGKSTTIKLLTGIMRPTTGRVRVDGLDPHRQ
FT                   RTRVAGRIGVVFGQRSQLWWDLPVLDSFRILRHVYEVPQAVYDRNMRLFRDRLDLGALG
FT                   NTPVRQLSLGQRMRAEIAASLLHDPAVVFLDEPTIGLDLVLKQAVRDLINHIHAELGTT
FT                   VMLTSHDIGDITSICDQALVVDRGTIVHQGTMRDLLRSVDTRAVTFEYAAGSVSEAAAL
FT                   RIITEGLPEVDATPAESGRIRVEFPVDRWSARQVIAFLLDRFDLSDVLVPDADLETLLR
FT                   RIYAGSRPEPVTAGDGA"
FT   CDS             8551..9912
FT                   /transl_table=11
FT                   /gene="acbV"
FT                   /product="dTDP-4-keto-6-deoxy-glucose 4-aminotransferase
FT                   AcbV"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q27GS4"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS4"
FT                   /experiment="RT-PCR, protein overexpression, enzyme tests"
FT                   /protein_id="CAJ81022.1"
FT                   /translation="MTRDVFRAGSFRHRRRDPAAVPVSRQADLLARESRHLAPGASEEA
FT                   ALGRRVFVEGRGATLRDADGVEYLDFAAGTLTQSLGHCHPEVVARLTEQAGKLWNVHDF
FT                   ATADRAALCELLAELLPDHLTTLAFFSTGAEVVEAALRTVQAVAEPGRNRVGALRHGFH
FT                   GKTMGARMLVHWDVGDQSFAGNSVLGYAPYCYRCPLELSYPSCEVRCATLVRRHIAEKP
FT                   NVSALFFEPVLGAAGVIVPPPGYWEQIAAACRDNGVLLVADEVLTGGGRTGTFLASEAI
FT                   GVAPDLVTLAKGTASGFPFAVLAGRDEVLRHPRAGLAGSTASTYAGNPLGIAAAHATLS
FT                   VISRDRLIEQVRDLGAVLADRLAEMHDRHPHLGDVRGIGLLHGLEFVHDRQSRRPAPEI
FT                   ARRVYTTALDAGLRTAIGGHIIRLAPPFVIDETELLRGLDLLDRAITEAGRVTA"
FT   CDS             9909..11387
FT                   /transl_table=11
FT                   /gene="acbU"
FT                   /product="putative kinase (1-epi-valienol-7-phosphate
FT                   1-kinase) AcbU"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q27GS3"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS3"
FT                   /protein_id="CAJ81023.1"
FT                   /translation="MTPRPVSTIDVSLASLLRTADWPHEDLRGPGGVRILDEAILGPSR
FT                   LLIVAAERNPESRYFVAVLRHDPSREAVGDAAHDRAVVQAMRERLALPTAAGHLIVFDG
FT                   DPAPFRATRPFDPGWSTNALSLADLDGTLHIHKAYRLVSAATREPHLLRLMHRGGRTQR
FT                   WAGDYHYVEQPSGRRYPLGLLYAYAEGDSLDLPLRHSIRSMWPALLGGTEPAGAVTAAQ
FT                   RSIAGELPGVGRFLRDFHTELAQRLEPAPTFPVNAYLRETAERVAALGCRISADERYPR
FT                   PVREAVVAALTGELDQATTSAVRVPWPAGPSHGDLHLSHILRRQTPDGWRLCVIDLSTP
FT                   APDPADPLGAAQSPWQDLVALLRGLEIFTADEFVHQAALRLGADQDDTCRTVLLISAGQ
FT                   TPDTPGWTGSRLTALRRMHDAASVWAGQVRRMLLSGYADGGEAAEEHPAWRIFRLRRLL
FT                   HELDYAYAHDQHYHAAINLRHVLQTYRPPVTGES"
FT   CDS             11392..13521
FT                   /transl_table=11
FT                   /gene="acbS"
FT                   /product="glycosyltransferase AcbS"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q27GS2"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS2"
FT                   /protein_id="CAJ81024.1"
FT                   /translation="MHIIETYFECGGFDHRFIQGGTSVYLWQLSRGLADLGHRVSIVTP
FT                   AHGRLDDLRRLHEVEDLPGTDEYELPLVLDPRVWGERFPAQMDIALRTTAHRIRLAGVD
FT                   LYFLSNELLDQLPDRFYPPYESKGVDLVFFKPLAYQVAAIRFIRSHFGDQRAIVHAHEP
FT                   FYHYLMPAAFAADPAKHVVSTVQSNMPINKSVYRAEVARLLGFLGAPNALPADDPAGSR
FT                   SPHTVAMSQYQQLTHLHYEYPPDHVRVYDLVAEHADRIDFLSPGHRDYYTCFADTPFAQ
FT                   LFATLPVSRTVRRNADKTFVGGCAVGDEWVTGELPPVDREKVLAGLGLDPDLPAFYHNA
FT                   RYAVNHKGQVELIRAVDRVLSGGVRASFIVRCLSDAGIADPLFHEVVARHPGRVNLEWH
FT                   RVPEDQLREYARAADFCLFPSKFEMDTFLIAQGEAMAAGAVPIATAQLGMAHFGHVADP
FT                   LTGPDAATATGFAVNRSFAEDDPLLVQGLTEQIRRAVTLWNEQPGQYRRLSANAVARAR
FT                   EFTWRRAAQAHEAAFAGVWAGRTPRLPVGDLLRFGWFDELPADAWTLHRDEIAEVALAH
FT                   GDADAYLRCRPDDLDALAALFERAWARADFPACARTVELAEEHRQERVPQWRARLAGRG
FT                   RIDRDGRLHYRPPSAERVELVLPDLAEPLRGTVTVTAMAPTGDTFTGQLPAGTRRADLL
FT                   LTLSDGRTVWDEVTA"
FT   CDS             13518..14609
FT                   /transl_table=11
FT                   /gene="acbR"
FT                   /product="putative
FT                   1-epi-valienol-1,7-bisphosphate-1-adenylyltransferase AcbR"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q27GS1"
FT                   /db_xref="InterPro:IPR005835"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS1"
FT                   /protein_id="CAJ81025.1"
FT                   /translation="MSTGVRAVLLAGGEGRRMGALGAGRLKPLVPFGGAARLIDFSLAN
FT                   ARDSGLDQVLLLSQYQERQLMDDLRRTWWQPGFRVHFGPYDRAYTDGIPVEYEPPTGPP
FT                   ERGTADALIRKAPYLFGPDVTEVLVQHADHVYRFDYRPMIAEHRASGAALTVSYQRIDR
FT                   RYVHLFGMVEFDDRNRLVSFVEKPAEPTSDLVFAAFCVFDAAVLHRYLELLDGTDWQHD
FT                   ISRDVIPAMLAAGEHIRGCPVPGYWADIGTVERYHEAHLSLVGTPPSLAVDAMPWTVAP
FT                   RTARALVTSADGVRHSVVPADLVNHGTVERSVLFPAARIGPGATVRDSVLLPGAVVPAG
FT                   AEIDGAVVLEDGTVQQVTTGARR"
FT   CDS             14606..15193
FT                   /transl_table=11
FT                   /gene="acbP"
FT                   /product="putative NUDIX hydrolase AcbP"
FT                   /db_xref="GOA:Q27GS0"
FT                   /db_xref="InterPro:IPR000086"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GS0"
FT                   /protein_id="CAJ81026.1"
FT                   /translation="MTGAVRAVRSREVYRNPWMSVREDDIVHADGSPGSYGVVTKPDYA
FT                   LIIPRDNGLLHLVEQYRYPVGGRFWEFPQGSWPADAAGGAADLLARTELAEETGLRAGR
FT                   LTPLGRIHVAYGYASQGCHVFLAEQLTAGRSQRERTESDMRQRAVDAAGWADLVGSGRI
FT                   TDAATLAAYTLLRMYDSGTRQPMPEGAESCTW"
FT   CDS             15181..17385
FT                   /transl_table=11
FT                   /gene="acbI"
FT                   /product="glycosyltransferase AcbI"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q27GR9"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR9"
FT                   /protein_id="CAJ81027.1"
FT                   /translation="MHVVSFAFEALAFDVGMMRGGLAPLAWELARHYAAQGHRSSIVTP
FT                   AHGRLPYLAERYDLVELDYRDEHVVPVVPDPDVWAGQPRELGLPLVTRAHLLRHEGVDI
FT                   YLLSDEYLDLLPERLYPAGTSEGSDLAYFKPLVFQVGGLRFLQSRLAGDEPAVVQAYEP
FT                   YYHYLLPPVLAGDPRFRVMSTVASSMPIDLGVYRPQVDRLLEHFGAGTDLDRYVESPVA
FT                   AGADHPAATREAALGAAMAGYLPTTRLSSGRRRADYVGLFALITDHCDTVDFLTPGQRR
FT                   FYSTFRDTPYEAAFRRTAVARVVRENAAKQFVGGCALPENWLRRDPAEVDRAAYLSGLG
FT                   LDPALPTFYHVGRYSPHHKGQVELFRAVERILATDTRVNFVLRCATSAGGGGARIGDPA
FT                   FQAVADRHPGQVRLFWTMADEDELFTEAVAADFGLFPSKYELDTFLTAQGQLCACGAVP
FT                   IGTAQESTRHYRHQLATDHPLATGFALPRSFTPDDERLTGALVRTMREALRMYRDEPGE
FT                   YRRLAGNAAELARTFRYAEVSRRRLAHFAKLLDGTPTAADPEHVIGCGWFDQLDAAQWA
FT                   AHLPQIRREAIRLGDLETLRRCGPVDPGALGALYEAAYRRADFDRCVRVAELLGDRGSE
FT                   AVSLRRRCRVRPHEQGWEIQYRAPGAEQVALVVGGTAHRMHGSAGRFSTVLPTVPMPSP
FT                   VFLLTLASGRYAWDAPPATAHLADLAGQPHPAQPVGAGGR"
FT   CDS             17387..18238
FT                   /transl_table=11
FT                   /gene="acbJ"
FT                   /product="putative hydrolase AcbJ"
FT                   /db_xref="GOA:Q27GR8"
FT                   /db_xref="InterPro:IPR000150"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR8"
FT                   /protein_id="CAJ81028.1"
FT                   /translation="MDGIGTTPPRDHRVVATDLDGTLLRSDLTVSARTRAALRDARAAG
FT                   MIHLAVTGRPVIDTRRLLAGLGYTGPAVCGQGAQVYDFGTDRLLLSRSLDTDLVRELVR
FT                   RIAQRTGPLALAAVSAGLGTEFLVTAGFGAPYQQHRWQLVDEPDLWRAPVAKVLIRHPD
FT                   HDDDTLAALADEVCGAALSVMHAGPGLVELLPGDTSKRTGLAFLAAELGFTGADTIAFG
FT                   DMPNDLPMFDWAGYGVAMANGHPRLRDRADEITVSNDADGVAVVLERLPAVRAGNRKAS
FT                   LR"
FT   CDS             18235..20331
FT                   /transl_table=11
FT                   /gene="acbQ"
FT                   /product="putative acarbose 4-alpha-glucanotransferase
FT                   AcbQ"
FT                   /function="acarbose degradation"
FT                   /db_xref="GOA:Q27GR7"
FT                   /db_xref="InterPro:IPR013781"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR7"
FT                   /protein_id="CAJ81029.1"
FT                   /translation="MTTTTDAALIELAGRYGVSVDWTTDRGEPRTVPADTIQRILAVLG
FT                   VDASSGPAIAAALRAADDDARHRLLPSCVVVRQGEPARGVHPVAGAAYVVATEDGGRHE
FT                   TADPRNDLGRLPIGYHTLRVRVGDRSAAAPVIVAPAVLGTPDRRHWGMLAQIYSVLSER
FT                   SWGMGDLGDLADLTRWSARLGASFVLVNPMHAYVPDRLADPTPYRPGSRRFADPMYLRL
FT                   ADVAEYATAEPAVRAELDRAARQGHELTAEVLHRNALIDRARVWPVKRNALERLYRAPR
FT                   TAGRSAALAAFTAREGRGLEDYATWCALAEVYGTRWRSWPAALQSPHGPAVAAARRELV
FT                   DRIDFHRWLAWLVDEQMAAAQAAAVGSGMAIGVIHDLAVGVDPEGADAWAVQDHLAGGV
FT                   TVGCPADDFNPLGQDWGLPPWRPDTLAEAGYRPFADVIRGTLRHSGALRLDHILGLFRL
FT                   WWIPAGSGARDGAYVRYDHEAMLGVLAVEAFRAGAMIIGEDLGTVHPAVRAELADRGIL
FT                   GTSVLRFEYQGGSENRSGPLPADQWRAGCLATLTTHDLPSTAAWLSGEHVDLQDRLGLL
FT                   NRPRAEVAADAAAERDGWLAELRRTGLLEHETAVPGMSAESLALHRFLARTPARLVGVW
FT                   LPDLVGDRRPQNLPGTSTEFPNWQLPVADADGRPVAMDDLASSAGAQAVAGLYAASAEP
FT                   ATTP"
FT   CDS             20363..21262
FT                   /transl_table=11
FT                   /gene="acbK"
FT                   /product="acarbose 7-kinase AcbK"
FT                   /function="phosphorylation of acarbose (intracellular
FT                   inactivation)"
FT                   /db_xref="GOA:Q8RMD4"
FT                   /db_xref="InterPro:IPR002173"
FT                   /db_xref="UniProtKB/TrEMBL:Q8RMD4"
FT                   /experiment="RT-PCR, protein overexpression, enzyme tests,
FT                   protein purification"
FT                   /protein_id="CAD29481.2"
FT                   /translation="MSEHTDVLVLGGAGVDTIAYVPELPLPFQDSYVVAAIEPRAGQTG
FT                   DNVALGLHTLGLRTMHVDVLGDDPEGDLVRAFHTRHGLPFAALPTAAGTKRAVNLVGPD
FT                   GRRLSLWDGSREAEEDRYPAALIAAHTAHARHVHVCITPPGQHVFGQLNDLPVTVSTDL
FT                   HNWDGAYEGFEVYAFNADLVFLSATALTDVAATMRRVIDRGRARLVVATDGAHGGSVLV
FT                   RGETEVRRYAAVAPEAPVVDSNGAGDAFVSGFLFGHLAGEPLETCLRYGAIAGAYACTI
FT                   PATRAGAIDRAALLRPAA"
FT   CDS             21259..22338
FT                   /transl_table=11
FT                   /gene="acbM"
FT                   /product="2-epi-5-epi-valiolone 7-kinase AcbM"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q8RIS8"
FT                   /db_xref="InterPro:IPR000408"
FT                   /db_xref="UniProtKB/TrEMBL:Q8RIS8"
FT                   /experiment="RT-PCR, protein overexpression, enzyme tests,
FT                   protein purification"
FT                   /protein_id="CAD29482.2"
FT                   /translation="MKRPPHHPVTVADVGGTHLRWARWSPDGGLGEVHTTPSPGHARRP
FT                   GAGAADLQAELIRELASRVEPGARAGVSLGAAMDHHSGTAYASAPLWGPQVSPFDVPAA
FT                   LRAARPDVHWTVVNDVTAGLLHLAEMVRDAGVRKACLVTISTGIACRTMDLRTGGIPVD
FT                   AAGLQGEIGHLPATVLADGVPVVTRCDCGEPGHVAASSSGPGIRRVAAVLARRDPATWA
FT                   GSGPTTRMMAGSGFEDAFRAALDDGDPVAADLLTAVTAPIADLLRTALCLDPELDLIAL
FT                   TGGVAHGLEPHYSAAVHDHLRRRGLYLTSEREPDWLTGRIRVVPPATADPLVGAGLAAL
FT                   AAGPVPAYSGGGREALVGR"
FT   CDS             22335..23435
FT                   /transl_table=11
FT                   /gene="acbL"
FT                   /product="cyclitol dehydrogenase AcbL"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q8RMD3"
FT                   /db_xref="InterPro:IPR013154"
FT                   /db_xref="UniProtKB/TrEMBL:Q8RMD3"
FT                   /protein_id="CAD29483.2"
FT                   /translation="MSRHRAIVRTGTGVVVADVPTPVPGPGELLVGTEWAGLCGTDIQM
FT                   LRGLRDDPEPIIGHEGIARVIAAGDGVPGTLRPGTLVAVNPTHRDDPSFLLGHNVPGLL
FT                   QERTLLPATAVSGGLVLPLPDGTDVTLGPLLEPLAVVSYALSQLGAVRPATLVIVGDGT
FT                   VGHLAARAAVTWLAERPRVVLVHHTAAGRDFSAAGPHPADVLLTTGELAGRPLPGPVAA
FT                   LLATPRDATVEALEAVLAAAGADVLIDVLGGLPPGARSAMLPGVDLTAVRAANCGGFPE
FT                   PALVTTTSGGTRLFGHRGVGNAHLRAAAGELARDPDRYRDLVTHRSDLAGAARIMTALR
FT                   SGRDRIIDGRRLVKLAIQVNVREDHR"
FT   CDS             23432..24187
FT                   /transl_table=11
FT                   /gene="acbN"
FT                   /product="cyclitol oxidoreductase AcbN"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q8RMD2"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q8RMD2"
FT                   /protein_id="CAD29484.1"
FT                   /translation="MSGTLVGRRALVVGGTTGIGRGIADAWAAAGAEVTVCGRSEPAGD
FT                   GAAGLHWEPLDLTRTGEAGARLERIAGDRVDLACFAAVSYGARRAVFEDVAVDEWRTQL
FT                   DINVHGLWLTLRAALPGLRAARPGLFVGVSSEVVYNAGPGRSGYTASKAAAKALLESVA
FT                   QEEDESRVRIVQVLPAGMVDTPSIRRRRPAGFDYSDYMVPADFARNALELAATAGAGHH
FT                   GDSLVVDRGGDWWSVRERMPVSQSRPVRT"
FT   CDS             24184..24996
FT                   /transl_table=11
FT                   /gene="acbO"
FT                   /product="2-epi-5-epi-valiolone-7-phosphate 2-epimerase
FT                   AcbO"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="InterPro:IPR013022"
FT                   /db_xref="UniProtKB/TrEMBL:Q8RMD1"
FT                   /experiment="RT-PCR, protein overexpression, enzyme tests"
FT                   /protein_id="CAD29485.2"
FT                   /translation="MTCRVGLTEWRLAPSGAAAIRLAAAVGADGIQLDFGGPGRGVLVD
FT                   GPGRAGQLRAVADEAGVDLLALAGNLLNDIGLTSQPAVVQPVLARLADTATELGVPLLI
FT                   VPSFRRSAITDAMSFTRTAAALRWAVSLAEARGIVLASENVLPPARARQLVEEVGSPAF
FT                   RLLLDTFNPVRYGLDPAWLATELRPWWADQIHLKDGPPDTGPSPLLGAGQGGVRRTLTA
FT                   LRGSPAPVRALVLENDYRDGHGARLRADLEWARRAAVNARESEKGKLT"
FT   CDS             complement(26253..27215)
FT                   /transl_table=11
FT                   /gene="acbB"
FT                   /product="dTDP-glucose 4,6-dehydratase AcbB"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q9ZAE8"
FT                   /db_xref="HSSP:1BXK"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9ZAE8"
FT                   /protein_id="CAA77209.2"
FT                   /translation="MKILVTGGAGFIGSHFVTSLISGDIATPQPVTQVTVVDKLGYGGN
FT                   LRNLAEASADPRFSFVRGDICDEGLIEGLMARHDTVAHFAAETHVDRSVVASGPFVASN
FT                   LVGTQVLLDAALRHHIGRFLHVSTDEVYGSIDTGSWAEGHPLAPNSPYAASKAGSDLLA
FT                   LAYHQTHGMDVVVTRCSNNYGPRQFPEKMIPLFVTRLLDGLDVPVYGDGRNIRDWLHVS
FT                   DHCRGLALALGAGRAGEVYHIGGGWEATNLELTEILLEACGAPASRISFVTDRKGHDRR
FT                   YSLDYSKIAGELGYRPRVDFTDGIAETVAWYRANRSWWT"
FT   CDS             24993..26147
FT                   /transl_table=11
FT                   /gene="acbC"
FT                   /product="2-epi-5-epi-valiolone synthase AcbC"
FT                   /function="cyclisation of sedo-heptulose-7-phosphate"
FT                   /db_xref="GOA:Q9ZAE9"
FT                   /db_xref="HSSP:1NVE"
FT                   /db_xref="InterPro:IPR002658"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9ZAE9"
FT                   /experiment="RT-PCR, protein overexpression, enzyme tests"
FT                   /protein_id="CAA77208.2"
FT                   /translation="MSGVETVGVHADAHRDSWQVRAQKQITYEVRFRDDVFGLDSTDLL
FT                   EAGADGAGSRRRFVVVDSAVDALYGSRIREYFTHHGIDHSILVMRVGETVKDFDTAGRI
FT                   VAAMDAFGLARRREPMIVVGGGVLMDVAGLVASLYRRGTPFLRVPTTLVGLIDAGVGAK
FT                   TGVNFNGHKNRLGTYAPADLTLLDRRFLATLDRRHLSNGLAEMLKIALIKDAELFQLLE
FT                   RHGRVLIEERFQGRTGTGDRAAVRALRAATHGMLEELGPNLWESRLERSVDYGHTFSPT
FT                   IEMRALPALLHGEAVCVDMALTTVLAYRRGLLDVAQRDRIFAVMTALGLPTWHPLLTPE
FT                   VLEAALQDTVRHRDGWQRLPLPVGIGGVTFVNDVTAGRAAGRPR"
FT   CDS             27298..28209
FT                   /transl_table=11
FT                   /gene="acbA"
FT                   /product="dTDP-glucose synthase AcbA"
FT                   /function="involved in acarbose biosynthesis"
FT                   /db_xref="GOA:Q9ZAE7"
FT                   /db_xref="HSSP:1H5R"
FT                   /db_xref="InterPro:IPR005835"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9ZAE7"
FT                   /protein_id="CAA77210.2"
FT                   /translation="MRGILLAGGTGSRLRPVTWAVSKQLMPVYDKPMIYYPLATLVSCG
FT                   IREILVITTETEAAQFQRLLGDGSQWGLRLEFAVQQRPGGIAEAFLIGEEFLAGGPVAL
FT                   MLGDNLLHGVDFRPCVQRARETAGGHVFGVAVADPSAYGVVEFDAAGRVLSIEEKPVRP
FT                   RSPYAVPGFYLYDADVVETARSLRPSARGELEITEVNQAYLRRGALSVTLLGRGAVWLD
FT                   TGTLADCMRAVDYVRAIDEGQGIKIGCVEEAAWRAGFLDTAQLRALAEPLMSSGYGQYL
FT                   LALTGDGLSRTPQWPALTAAAG"
FT   CDS             complement(28302..31418)
FT                   /transl_table=11
FT                   /gene="acbE"
FT                   /product="acarbose resistent alpha-amylase AcbE"
FT                   /function="extracellular starch degradation"
FT                   /EC_number="3.2.1.1"
FT                   /db_xref="GOA:Q27GR6"
FT                   /db_xref="InterPro:IPR005323"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR6"
FT                   /experiment="RT-PCR, protein overexpression, enzyme tests"
FT                   /protein_id="CAJ81030.1"
FT                   /translation="MDERLKSHIVRALLPVLVGAAGGLPAPRAAQAESPPDRPSHAEQL
FT                   YLVMPDRFANGDTGNDQGGLTGDRLTTGYDPTDAGFYHGGDIQGVIDKLDYIQGLGTTA
FT                   IWLTPIFKNKPVQGTGPNASAGYHGYWITDFTQVDPHFGTNEDLKRLVGLAHRRGMKIY
FT                   LDIVVNHTADVIKNAEGTAYADKGTAPYRDTAGRPFEDRNYADGTHGFPKVDEKSFPHR
FT                   PFFEKPSDATAKAPAWLNDPTMYHNRGETTFGGENAEYGDFTGGLDDLWTERPEVLHGL
FT                   TDIYAGWIRRFGVDGYRLDTLKATDLAFWRPFAEGVGKAADKAGKRDFFLFGEAWSKDQ
FT                   EVTSTFVRRGGLPATLDFPFQGAAQSYARGQGTGQQPWQDLYAKDDLYSRRPGPTPAGC
FT                   HLGEWNHDMGRIATLIKAGSDPKRGCRLELVNELMFLTRGQPGGLLRADEQGFTGRPRL
FT                   NKGSRQDMFASRTPDYLDDRLIGTDKTHASDNHDTGHPLYRTIAELGAVRKAHPGLRDG
FT                   EQITRYAADRAGVFAASRIDRDQRAEYVIAVNNATTAQTVTFDTYTPGCGFQPLYGTGE
FT                   TAATGADGRLTITVPALSAVAYRAEKPIPAADGAPAVTITAPAGRDPRAGPHRTDRAVT
FT                   GDPLSTVTFSARAGNGPWQPIGTAGRGPYRVFHDLTGLAGGAEVQYRRSPGTPRPYRHH
FT                   HQPDPVGTVRAEAGYAVVHYQRPAGDYDGWRLHATGERSKRPRSNPQGEPFTGNGTPNG
FT                   PFAWVKLRPGATKVTFTVSDANGVKDVDADRSLNPQQTPGIWLHQGDPAISYQGPAPAP
FT                   APNTAILHYRRPAGDYTGWGLHLWDGAATPTADWGAPLLPESFDSFGAVFRIPLAAGAT
FT                   GLSYIMHAGEAKDLPTDQRLEFADAGREVWVQAGVQERLLPSVVKPAKLDLTRADAVRV
FT                   DRDTIAWQTGTPDTLEPAGAATDGRVYDLVHAPNGGLRLVDGDLAGDYRSIRLTAQRDG
FT                   LTEKQRRQAPELWQYPAFQAAAALPSGDGQFYVTERDAQGRLMSVTGVR"
FT   CDS             31744..33918
FT                   /transl_table=11
FT                   /gene="acbD"
FT                   /product="acarviose transferase (ATase) AcbD"
FT                   /function="extracellular transfer of acarviose, involved in
FT                   acarbose metabolism"
FT                   /EC_number="2.4.1.19"
FT                   /db_xref="GOA:Q27GR5"
FT                   /db_xref="InterPro:IPR013781"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR5"
FT                   /protein_id="CAJ81031.1"
FT                   /translation="MQRHARHAIAAAVAVSLLPPSLPAHAAGASAVVPYAGNPASLKQD
FT                   LCYQIATDRFSDGNPANNNPGNVPGMFADKTKLNDRQEWLKYMGGDFAGITQRMEYLKN
FT                   LGVGAIWISPHVDNINVPANGATGYHGYWPRDFKRLEEHFGTDEEFDALVSAAHASNIK
FT                   VIMDWTPNGTNPPNQAEDGALYDDGQLVGRYGADSAGHFHHGPAIGDFNDRYQDQYYSL
FT                   ADIADLDQQNPRVDQLLKDDANYWMDRGVDGIRVDAVKHMPLSWQRSFADAVTSHKSAA
FT                   IFGEWYMGDQSDPLYADQVKFANTSGIAAMDFYTNRSIRDTFAGAGSMKSLDAAITKTN
FT                   RDYLYEQDLITFLDNQDTRRFGTLNSDPAALHRALAFLLTTRGTPCLFYGTEQYLHNDT
FT                   GEGSNKGKDPYNRPPMASFDTDTVAYREIRALSDLRRSNPAVAYGDHQQRWINDDVYVY
FT                   ERRFGDNVLLTAINKGSHEYRLDGLRTALPAGTYRDVLGGTFGGSDLTVEDGDGTDRST
FT                   VAPVLGAGQVAVWSYRAPVDTEPRIGGVGPVVTRAGATVTVEGTGFGSGGTVAIGGVPA
FT                   TVQQWTADRITATVPVGVPTGAVQVTVGNGSGTSNGYPITTRTGKPVPVQFTVQNPPAT
FT                   APGESLYLTGDVAELGHWSTSPDQTAGQLLRVPNESRGVLVADLPAGAPVEFKFVKVAA
FT                   DGTVTWEGGANHRYTVPAGGTGTTTLTWQR"
FT   CDS             complement(34153..34944)
FT                   /transl_table=11
FT                   /gene="acbG"
FT                   /product="ABC transporter membrane protein AcbG"
FT                   /function="uptake of acarbose and acarbose homologs"
FT                   /db_xref="GOA:Q27GR4"
FT                   /db_xref="InterPro:IPR000515"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR4"
FT                   /protein_id="CAJ81032.1"
FT                   /translation="MPIVFALYVALRPIEETNQSGYVSLPHQMTLSNFAHAWTRSGMWR
FT                   FFLNSVYVTVPAVLITLLLASMAAYVLSRLGFRFNIPLLILFTAGNLLPQQVIITPLYR
FT                   IYLAVHLPSWLSGSGLLYNSYAGLILINVSFQLGFCVFVLSNYMKTLPPAIDEAALIDG
FT                   ATLWSRYWRLTMPLCRPALAALATLLTTWIYNDFFWAITLISTGDRRPITSALANLQGQ
FT                   FVSNQNLIAAAALIAAIPTLVVYLLLQKQFIAGLSLGSTKG"
FT   CDS             complement(34995..35975)
FT                   /transl_table=11
FT                   /gene="acbF"
FT                   /product="ABC transporter membrane protein AcbF"
FT                   /function="uptake of acarbose and acarbose homologs"
FT                   /db_xref="GOA:Q27GR3"
FT                   /db_xref="InterPro:IPR000515"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR3"
FT                   /protein_id="CAJ81033.1"
FT                   /translation="MTPTIRPAPAARRRRRTLTRRDVAVAAAMLGVPLLLDLAFIWFPA
FT                   LASVLLSFTKWTGIGSIRMRSCADFPSAPGIPQPGCLNGVDNYRQAFTNYPDFWPAVRH
FT                   NAIWLVVFILLATPLGMLFAVVIDRGVRGSRFYQSVLFLPVMLSLALIGIIWELIYSPN
FT                   FGLINTVLGHNHNDNLIDWLGNPRLNLWALLVEASWRQAPYVMVLYLAGLKAVDPALRE
FT                   AAIVDGANAWQTFWRVVFPAMRPINIVVLVVTVIESLRAFDLVYITSNGNPLRGLELLS
FT                   VAVTQNIVGETQRIGFGSTLGVVLLVISLVPISLFLWQAFRREER"
FT   CDS             complement(35975..37276)
FT                   /transl_table=11
FT                   /gene="AcbH"
FT                   /product="ABC transporter binding protein AcbH"
FT                   /function="uptake of acarbose and acarbose homologs"
FT                   /db_xref="GOA:Q27GR2"
FT                   /db_xref="InterPro:IPR017909"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR2"
FT                   /experiment="RT-PCR, overexpression, enzyme tests, protein
FT                   purification, binding assays with substrates"
FT                   /protein_id="CAJ81034.1"
FT                   /translation="MTRFDSAGLTRRSLIGLTGAAATATLLAACGSDDKSGTTSVSDGN
FT                   GPITFGSNYSDEAPKAAFASLMQQATTSTTVPVTVNTTDHNTFQNNISNYLQGTPDSLA
FT                   TWFAGYRLQFFAAQGLLTPIDDVWDKIGGTFNDAAKSLSKGLDGHYYLVPLYNYPWVVF
FT                   YNKSVFQSKGYEVPASWEAFIALARKMQSDGLVPLAFADKDGWPALGTFDILNLRINGY
FT                   DYHIKLMKHEVPWTDPGVTKVFDQWRELAAYQQKGANGRTWQDAAKALENKQAGMMFQG
FT                   SNQVAANYSAKNLPDLDFFVFPAINPQYGTDYMDAPTDGFILPKKGKNAAAAKKVLQYI
FT                   GTAEAEAAFLKTDHWDVGLANGLIAPTYNDIQKKSVAEIGKCKSVSQFMDRDTVPDMAN
FT                   AMIKLIQQFIDQPTPETIATVQKSAEDQAKTIFR"
FT   CDS             37518..39875
FT                   /transl_table=11
FT                   /gene="asp3.1"
FT                   /product="putative galactocerebrosidase"
FT                   /function="putatively involved in xylane degradation"
FT                   /db_xref="GOA:Q27GR1"
FT                   /db_xref="InterPro:IPR013781"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR1"
FT                   /protein_id="CAJ81035.1"
FT                   /translation="MRHLLMVAVTAAAIGTLAAPAPAAAATTVALNGGIVGRAFDGVGA
FT                   ISGGGGNSRLLIDYPEPQRGQILDYLFKPGYGAAVQLLKLEIGGDANSTDGSEPSHQHV
FT                   RGDINCNAGYEFWLGEQAVARNPGIRLVALPWAAPGWIGGGSFWSTDMINYDVSWLNCA
FT                   RQYGLTISYLGGWNERGHDSTWYKNLRTGLDNAGYSAVQIVGDDSGWGMADEFAADPTL
FT                   KNAVGVLGNHYVCGYLSQADSCSTTGNARSSGKPLWASEFGSQDDNAGVVPYIRTVNRG
FT                   YLDAEISGYMNWPLIAAITPNLPFATVGLMDAGSPWSGAYRVGRNLWANAHYAQFTQPG
FT                   WHYLNSSASGYLGGNRANGSYVTLKSTNNTDYSTIYETSGSTAAQTVNVTVSGGLSTGT
FT                   VHVWSTDMGSSNSADWFVRQADITPVGATYTLNLQPNRIYTVTTTTGQGKGTAAGPAPH
FT                   GLALPYSDNFDGYAVRKLPHYSEDMQGSFETRACSAGRGGTCLQQVAPLRPINWQDDSD
FT                   AFTLFGDTGWTNYTVSLDVNMQQAGTVTLLGRANIQNRPQNRQAAYQLRVTDNGGWSIV
FT                   KHTNADTDTTLVSGTRAALGLNSWHNLRLGFSGGQITAAIDNTTVGTVTDYAYGAGQAG
FT                   VGVVGYQTDQFDNLSVTPNSGPALNTLRGVESGRCADVPGASQTNGTQLALWDCNGGSN
FT                   QNFTLTDQKQLLVYGSKCLDVNAGGTADGAKVQIWDCHGGTNQQWTLNADGTIVGIGSG
FT                   KCLDATGHGTANGTLLEIWTCNGGDNQKWSRS"
FT   CDS             39872..40936
FT                   /transl_table=11
FT                   /gene="asp3.2"
FT                   /product="putative xylanase"
FT                   /function="putatively involved in xylane degradation"
FT                   /db_xref="GOA:Q27GR0"
FT                   /db_xref="InterPro:IPR000772"
FT                   /db_xref="UniProtKB/TrEMBL:Q27GR0"
FT                   /protein_id="CAJ81036.1"
FT                   /translation="MKRLAALLSIGILGLALAAPAQAAESNGGVRVMPLGDSITDGYNV
FT                   PGGYRIGLWQRLAADGHLTDLVGSGSNGPAGLGDHDHEGHPGWRIDQLDAAIVGWIQQA
FT                   DPRTILLHIGTNDIGQNYDVANAPARLSALIDKIRVNAPQVQLFVAQIIPTANAANEQK
FT                   TQTFNAALPGIVAQKGPLTHLVDQHSALTTADLADGVHPNAAGYDRMAARWYAALQSVP
FT                   GSLTTLTTPPVGATVLLSNPQSRRCLDVGTTVSLWDCHGAANQQWVRTAAGELRNGADC
FT                   LDATGAGTANGTRLIIWPCHGGANQHFTFHPDGTIVGVPSGRCVDLNANGTANGTIVQL
FT                   WDCNRGANQVWSAR"
XX
SQ   Sequence 41323 BP; 6157 A; 14581 C; 14671 G; 5914 T; 0 other;
     tggatcgaag gtcagcacga agtcgatggc atcgtcgtgg cgccgtcgcg tgcacagagc        60
     cacggtgaca tgcgggtcca cgatcaccag cgccgcctcc gactccaccc cgctcagtcc       120
     atcggtgatc gacgtgcgaa tcggcgaagg agctggcagg cccgggccgg gaccggagac       180
     acccaccagc gccgcggtcg atgccgcgtc ggccagccgc ggaatccagc cgtgtcccgt       240
     cgcgaggtcc ggatacgcgc ccaggaccac gccgtacggg ccggcgaacg gcaattgcct       300
     caagacgtgt gcggtgagcc cgtcgaggag atgccggtcc ccggtccggg cgcggtggcg       360
     agccgaggcc atatcgaacg ggctggcacc gggtacgtac aactcagggc ggggagcacg       420
     caaccgagcc gacgggtcga ccggccaatc ccgcacggcg gacagcggcc caggccgggc       480
     gaacaaccat ccctgccccc agccggcgcc caaggcgcgt gccacctgga gatcctgctc       540
     cgtctcgatg ccctcggcga tcaccatcgc accggtccgc tgggcgtatc cgcacaccag       600
     cgcggtcgtc tcgatggtgt gtgcgcagta cgggtcgcgc agcaggtgca tgtcgagctt       660
     gacgacctcc ggctccaaca gcggcaggaa ggccagcgac agccggtccg caccaacatc       720
     gtcgagcgcc agcgcaccgc cggtgcggtg cgcccgggcg gcgacctcaa gcagcgccga       780
     cgggtgcgcc gccagggcac gctcggtgaa ctccagcacg tatcggtagg tcgagatcga       840
     ggcgagccgt aatcgcaggt cctcgctgag cggccgatcc gccccggcgg gttccttgtt       900
     gatgaacacc agcggtggca ccaccgctcc gggggcctga gcgatctcat gtgcccgggc       960
     ggcgcacaac tggtccagct ccggcaccag gtcaacccgc gcagcggcct cgaacaactg      1020
     gtccgggaac tccagcgggg atcctgccgg cccacgcgca agcgcctccg cccccaccag      1080
     ccggcgggta tcgaggtcga cgatgggctg gaacagcggc tcaacggcac gctcggccac      1140
     tacacgggag atgagcgcga cagactcgtt ccgggcgtca cacacctgcc tgttcctctg      1200
     gatcacacca ccagtcccgt ccgagatggt ttccgcactt ctgctgatcg gctgacaccc      1260
     ggctcacctg agcactcgcg actccatgga ttcgaagacc tgcttatcgg cattcatgcc      1320
     tgccgcctgc tctgtgccga acacgcggac gaccttgccg acgaggacga cgataccgag      1380
     gagcgccatg acgagatcga cgaagcgttc gtgtggctgt gcgtgcccgt acagctcaag      1440
     atcgaggatc tggtggccgg cgggttgatc cgcgaggtgc ggccggagtc tgccggtgcg      1500
     gcgctttccg ggcggatgcg tgccgagtgg caggccgtcc cgcagcaagt gccttccccg      1560
     ctgacggcat cgagagacat cgttgctggg ggcgctccca tcgcaacggt gcgtccacag      1620
     tgttaacggc tggcgacaga cggcttcccg gctgtttgca agtgcttcca cgtgatgcaa      1680
     gagtttgcta gcttcgtgcg gtgcggtgac gccgctggcg gccatcgatg aagcgccggc      1740
     ctctccggac ggcgggcgcc cccgcgggca ccgcaccacg ttccccgtca cgccccgagg      1800
     agggccgcgt cttggttctg tcccgtcatc gcgacgtcat gcgtcgcctg tccgccgtgc      1860
     tggcgctcgg cctggtggtg cccctgctgc tggcgccacc gtggcgggcg tcggccgcgc      1920
     cggccggcgc ggccgagccg agcgccgcgg ccctggccca ttggggagcc gaccggccgg      1980
     cacccgccga acagttctac ttcgtcctgc ccgaccggtt cgccgacggg aacccgaaga      2040
     acgacaccgg cggtctctcc ggcgaccggc tctccaccgg gtacgacccc accgacaagg      2100
     gcttctacca cggtggggac atccaggggg tgatcgacaa gctggactac atccaggggc      2160
     tcggcaccac cgccatctgg ctggccccgg tcttcaagaa tcggccggtg caggggaccg      2220
     gcgccgccgc ctcggccggc taccacggtt actgggtcac cgacttcacc caggtcgacc      2280
     cgcacttcgg caccaacgcc gacctcaagc gcctggtgca gctggcacac cggcggggcc      2340
     tgaagatcta cctggacatc atcgtcaacc acaccgccga cgtcatccag aacgagggcg      2400
     gcaagagcac gtacgtggac aaggccgacg ccccgtaccg ggacagccgg ggccggccgt      2460
     tcgaggacca caactacgcc gacggctcgc ggccgttccc gaaggtgaac ctgcagtcgt      2520
     tcccgtacac gccggtcttc gccagccccg ccgacgccac ggcgaaggtc ccggcctggc      2580
     tgaacgaccc gaccatgtac cacaaccgcg gcaattcgct gttcagtggg gagaacagcg      2640
     agtacggcga ccacaccggc ctcgacgacc tgtggaccga gcggcccgaa gtggtccgcg      2700
     gcatgaccga gatctacgcc gactggatcc gggacgccga catcgacggc taccggatgg      2760
     acaccgtcaa gcacagcaac atcgagttct ggcagcagtt caacccggcc atccagcagg      2820
     ccgcgcgacg ggccggcaaa cccggcttct tcatgttcgg cgaggtcttc agcgccgacc      2880
     aggaggtgga gagccgatac gtccggcagg gcggcctggc cgcgtccctg gacttctcct      2940
     tccagtcggc ggcccgcacg ttcgtctccg gtgacacgcc ggccaccgcg ctggccgacc      3000
     tttaccgaca cgacgacctc tacaccgccc gcgacaccgg ggccggccgg atgcccacct      3060
     tcctcggcaa ccacgacatc ggccggatcg gctcgttcat caccaccggc ggcgccgacc      3120
     ggaccagtta cctgcggcgc gaccagctgg cccacgagct gatgttcctc acccgcgggc      3180
     agccggtggt ctactccggc gacgagcagg gcttcaccgg gccgggcggg gacaaagacg      3240
     cccggcagga catgttcgcc agccggacgc cggactacct cgacgacgac ctgatcggca      3300
     ccgaccggac ccacgcgagc gacaactacg acaccgggca cccgctctac cgcaccatcg      3360
     ccgagctggg cgcgctgcgt aaggcgaacc cggcgctacg cgacggcgtg cagatcaccc      3420
     ggtacgcggc gcccggcgcc ggcatcttcg cgttctcccg ggtcgacccg gtccgacgcc      3480
     aggaatacct ggtcgcggtc aacaacgcca ccaccgcaca gacggccacc gtcggcaccg      3540
     ccacgccggg cagcaccttc accggcgtct accgcgcggg cggtaccgcc gccaccggct      3600
     ccgacggcaa gctcacggtg accgtgcccg ccctgtccgc ggtggtctac cggggcggca      3660
     gccccatcgc ggtcccgtcg gcccggccca ccgtgcggat cagcgcaccg gccgcggggg      3720
     cgtccgtgcc gtcgcgggcc gatctggtcg ccgacgtcac cggcgatccg ctggccacgg      3780
     tgaccttcgc ggcgcaggcc ggatccggcc cgtggaccgt gatcggcacc gcgcggcagg      3840
     ccccgtacca ggttcaccac gacctgaccg gtctggccgg cggggtcacc gtgaggtaca      3900
     aggcggtggt ccgggacggt cgcggacgta ccgcgagctc cacctcgtcg ctgcgggtcg      3960
     gcaccccgga cacccacgtc gcgccggagc ggatggtggt gcactaccag cggcccgccg      4020
     gtgactacgg cgcctggcgg ttgtacgcct tcggcgacat cgacgcgtcc gcccagacca      4080
     cctacccgga cgggcagccg ttcgccggcc aggacgagta cggcgcgttc gcctgggtga      4140
     gactcaagcc cggcgccaag aacgccggtt tcgtcgtggt ggacggcaac ggcgtcaagg      4200
     acgtccagca ggaccggttc gtcgacccgg gccgacaacc ggagatctgg ctgaaagcgg      4260
     gcgacgcgac ggtgtacccg tcccggcagg acgccaccgg ccggcccgac ccgcaaccgg      4320
     acccgaagac cgccgtcctg cactaccggc gcgccgacgg cgactacacc ggatggggcc      4380
     tgcacgtctg ggacggcgcg gcccagccca ccgagtggac ggcgccgctg gccccgtccg      4440
     ggcgcgacgc ctacggtgtc acgttccggg tgccgctcgc cgacggcgcc actggggtca      4500
     gctacgtcct gcacgccggt gacaccaagg accagccgac cgatcagcgg atcgacttcg      4560
     ccgccggccg tgaggtgtgg ctgctcgacg gggtggccga gcgcctgctg ccggtgaccc      4620
     gccggaccgc ggccggcgcc gggatcgatg tgacgacctc gcgcgccggg tgggccagcc      4680
     gggacacggt ggtctggaac accggtgtgg gcagcacctt gcagccggtc ggcggtggca      4740
     ccgacgggcg ggtgtacgag ctggcctacg ccccggtcgg ggggatcacc gtggtcggcg      4800
     gggagctggc gggggcgtac cggaccctgc ggctcaccgc gcagcgtgac ggcctgaccg      4860
     agagccagcg agtccggttc ccgaagctgt ggcggtacgg cgccttccgc gtcgccgacg      4920
     ccgaccggca ccgtctcgcc acggcgttgc gcggtcaggt ggtgatcacc gaacgggacg      4980
     cctcgggcaa gctgctcgcg gccaccggtg tgggcgccgc cggtgacctc accggctgac      5040
     cggagaccgg gatgatcggg gcgcccgcgc cgagcgcgcg ggcccccgat cgcggtgaac      5100
     cggtcagctg ccgggcatct cgtagcgccg cagcccgagc cggaaggtgc cgtaccccag      5160
     caggacggtg agcgtggtga ccggcagcat ccacagcagc ggcccggcgt ccccggtgag      5220
     caggtagcgc accggtaggt aggcggtgaa cgcgaacggc agcacccagg tgagcacccc      5280
     gcgcagcacc gggtggtaga ggttgagcgg gtacgcggtg aactcgctga gctggttgac      5340
     cgccaccatc acgttgaggc tgctggtcat ccagaacgac agggaggcca ggaacgcctt      5400
     gaggaaggtg tggatcaggg cgccgccgag gaccaggggc agcaacagca gccactgtgc      5460
     cacggtcagg tgcaggtcca tcgtcccggc cgcggtgacc acgatggcga tgccggtggc      5520
     cagctccccg aacccgtccg gatagaggaa ccgttcggac agcagcgcgt agaacgggtt      5580
     caccggccgg atcaggtagc ggaagaagtc gccggtgcgc accagctgcc aggccaggat      5640
     ccacagctgg tcggtgaaga gccggtccag cccgcggggc agcagggaga acccgagcag      5700
     gaacagcgcc tgctggcggg tccagccgcc gagcgccgga acgtactgga agatcacccc      5760
     gatcagggcg atctggcagg cgatccggat gacgaagctg gccgccccga tgaggaagtc      5820
     catccggtac gcggtgagcc ggtgcaggct cgccccgcac agcaccgccg tgaggcgcag      5880
     gtaccggcgc gccgtggaga cggtcatccg ccgagcacct ccaccctgcg cagcgaccgg      5940
     ttccaggcca gggccagcac gccgtacagc agtaccgccc agagcgcctg gacaccgagg      6000
     atggcagcgg cgccggaacc gccggagtag ccgccgagca gcagccgcaa cgggctgtcg      6060
     atcaggccct ggaacggcag cagccgcagc agccgggcca cgccgtccgg gaacagcgcg      6120
     agcgggacga cctggccggc caggaaggcg acgagcgcgt tcttgatcgt acggatgccc      6180
     caggtgttgg tcgtgacgaa ggcggcgaga cccaccagga agttgatctc gaaggcgagg      6240
     atcaccgaga gcagcagcgc gacggcgaac agcagcaggt tggcgggcgg gggagcgggc      6300
     agcgacgcga acatcgcgaa accggcgagc accggggcgc cggccagcag cgcactgagc      6360
     gcggcggtcg gcaggttcac cgccagacag ctgagcgcgt agttcgccgg gcgtaccagg      6420
     gagaccgcga tgtccccgcg gtacacctcg ccggcgatca tctcgtcgat ccggttggtg      6480
     tgcagcatcc cgagcacctg cgcgagcacg atgtacgagg tgagctgtgc gaacgggagg      6540
     ccggccggtg ccggtccgcc ggcgtagacg gctcgccaca ggaacacctg caacgaggtg      6600
     gccgcagccg ccgtgagtgc gctcaggacg atggtcgagc ggtaacgggt gacggcgtgc      6660
     agtccggcga gggcgaacgg cgcgtaccgg cgcgcggcgc ggatcatgcg ccgtccccgg      6720
     cggtgaccgg ctccgggcgc gacccggcgt agatgcggcg cagcagtgtc tccagatcgg      6780
     cgtccggcac cagcacgtcg ctcaggtcga accggtccag caggaaggcg atcacctgcc      6840
     gggccgacca gcggtccacc gggaactcga cccggatccg gccggactcg gccggagtgg      6900
     cgtccacctc gggcagtcct tcggtgatga tgcgcagcgc ggcggcctcg gagacgctgc      6960
     cggcggcgta ctcgaaggtg accgcccggg tgtccaccga ccgcagcagg tcccgcatcg      7020
     ttccctggtg gacgatcgtc ccgcggtcca cgaccagcgc ctgatcgcag atgctggtga      7080
     tgtcgccgat gtcgtggctg gtcagcatga ccgtggtgcc cagttcggcg tggatgtggt      7140
     tgatcaggtc ccggaccgcc tgcttgagga ccaggtccag gccgatggtg ggttcgtcga      7200
     ggaagaccac ggccgggtcg tgcagcagcg aggcggcgat ctcggcccgc atgcgctggc      7260
     ccaggctcag ctggcggacc ggggtgttgc cgagggcgcc gaggtccagc cggtcccgga      7320
     acaggcgcat gttccggtcg tacaccgcct gcggcacctc gtagacgtgc cgcaggatgc      7380
     ggaacgagtc gaggaccggc agatcccacc agagctggct gcgctggccg aagaccacgc      7440
     cgatccggcc ggcgacccgg gtgcgctgcc ggtgcgggtc gaggccgtcg acccggaccc      7500
     gcccggtggt cgggcgcatg atgccggtca ggagtttgat cgtggtggac ttgcccgcgc      7560
     cgttcgcccc gatgtaggcg atcttgacac cggacgggac ctcgaagctg atgtcgtcga      7620
     cggcccggac cacgtcgtac cgggccgaga acatggttcg caggctgccc cgcagacccg      7680
     gctcgcgccg gtagcgcttg aagtgcttgc tgaggtgctc ggcgacgatc atgccggtcg      7740
     tgccgtccgg ccgggcatgc cgggcgtacc cgggcatggc gagtcgagat gattcacgga      7800
     tcctcgtttc ttttccggaa gatgtcgtgg cggcaacatt ttgaaattga tgattaccat      7860
     caattaaccg agtttccaca atgtcgcgcc ggtctcggcg accggctata tggaagcaat      7920
     ccgaacagtc ggccggagga tgttgtcgac ggtgtgacaa tccgcgggcg gccggcgccg      7980
     cgctgcgccg gagtgcggcc ggccatcctc gttgtccgag gtgctgaggg gcacggccga      8040
     tcgctcggta gggggagggc ggtcatccgc tgtgcggtgc gggatcagcc aagtgagcat      8100
     tgaatgcgat tgcggcggca ctcgtcaagc cgccgtgccc ggtcctcgaa atgtgaccgc      8160
     gaaacctttc ccgtccgata tggagtgacc ggcgtcataa tttgttgttt cgggcaacaa      8220
     acccatcgcc gatcctcgat atattaccag ccggcttttc cgacattcgg ccagatgaat      8280
     gcggttacag acgggaccgg cgggtggggc cggatggtgg gcggggttgc ggaggggcgg      8340
     ccggtgaacg atgcaagaac ttgctgaaac tttcaggtcc agttgcggtg ccggtttcac      8400
     cgccatagat ttcgcggtca tcgggcctcg acggttccga tccggcccgg ctgagtgtgc      8460
     ggctcgctgg gcggtgcagc gacgccgacg tcgcttgaac cccgaacttc cagcccatct      8520
     caccggatgc ggcggctatc cccttcagga gtgacccgtg atgtgttccg agccggttcg      8580
     tttcgacacc ggcgccgcga cccggcggcg gttccggtga gcaggcaggc cgacctgctc      8640
     gcccgggagt cgcgtcacct ggctccggga gcctccgaag aggcggcgct cggccggcgg      8700
     gtgttcgtcg agggccgcgg cgcgaccctg cgcgacgccg acggtgtgga atacctcgac      8760
     ttcgccgccg gtactttgac ccagtcactc gggcactgcc accccgaggt ggtggcccgg      8820
     ctcaccgaac aggccgggaa gctgtggaac gtccacgact tcgcgaccgc cgaccgcgcc      8880
     gcgctctgcg aactgctcgc cgaactgctg cccgaccacc tcaccacgct cgccttcttc      8940
     tcgaccggcg ccgaggtggt ggaggcggca ctgcggacgg tccaggccgt cgccgaaccc      9000
     ggccgcaacc gggtcggggc actgcggcac ggcttccacg gcaagacgat gggcgcccgc      9060
     atgctggtgc actgggacgt gggggaccag tcgttcgccg gcaacagcgt gctggggtac      9120
     gccccgtact gctaccggtg cccgctggag ctgagctatc cgtcgtgcga ggtccgatgc      9180
     gccaccctgg tacgccggca catcgccgag aaacccaacg tgagcgccct gttcttcgaa      9240
     ccggtgctgg gcgcggccgg cgtgatcgtg ccgccaccgg gctactggga gcagatcgcg      9300
     gccgcgtgcc gggacaacgg cgtactgctg gtcgccgacg aggtgctcac cggcggcggc      9360
     cggaccggaa cctttctggc cagcgaggcg atcggggtcg ccccggatct ggtcacgttg      9420
     gccaagggca ccgcgtccgg tttcccgttc gccgtgctcg ccgggcgtga cgaggtgctg      9480
     cggcatcccc gggccgggct cgccggatcg accgcctcca cctacgccgg caacccgctc      9540
     gggatcgccg ccgcccacgc caccctctcg gtgatctccc gcgaccggct gatcgagcag      9600
     gtccgggacc tcggcgcggt gctggccgac cgcctggccg agatgcacga ccggcacccg      9660
     cacctgggcg acgtgcgcgg catcggcctg ctgcacgggc tcgagttcgt gcacgaccgg      9720
     cagagccggc ggccggcccc ggagatcgcc cggcgggtct acaccaccgc cctcgacgcc      9780
     ggtctgcgca ccgccatcgg cgggcacatc atccggctcg cgccgccgtt cgtcatcgac      9840
     gagaccgagc tgctgcgcgg cctggacctg ctggaccggg cgattaccga ggccgggcgg      9900
     gtgacggcat gacaccccgg ccggtcagca cgatcgacgt gagcctcgcc agcctgctgc      9960
     gcaccgccga ctggccgcac gaggatctgc gcggtcccgg cggggtgcgg atcctcgacg     10020
     aggcgatcct cggcccgtcc cggttgctga tcgtcgcggc cgaacggaac cccgagagcc     10080
     gctacttcgt cgccgttctg cgccacgatc cgtcccggga ggccgtcggc gacgccgccc     10140
     acgaccgggc cgtggtccag gcgatgcgcg agcggctggc actacccacc gcagccggcc     10200
     atctgatcgt cttcgacggt gaccccgcgc cgttccgagc cacccggccg ttcgaccccg     10260
     ggtggtcgac caacgccctg tcgctggccg atctggacgg gacactgcac atccacaagg     10320
     cgtaccggct ggtgtcggcc gccacccggg aaccgcatct gctgcggctg atgcatcgcg     10380
     gcggccgtac ccagcgatgg gccggcgact accactacgt ggagcagccc tccgggcgcc     10440
     gctacccgct gggcctgctc tacgcctatg ccgaaggcga cagcctcgac ctgccgctgc     10500
     ggcacagcat ccggtcgatg tggccggcgc tgctgggcgg caccgaaccg gccggcgcgg     10560
     tgacggccgc gcagcggtcc atcgcgggcg agctgcccgg cgtcggccgg ttcctccgcg     10620
     acttccatac cgaactggcg cagcggctgg aacccgcgcc gacgttcccg gtgaacgcct     10680
     acctgcggga gaccgccgag cgggtggcgg cgctggggtg ccggatcagc gccgacgaac     10740
     gttacccccg gccggtgcgc gaggcggtcg tcgccgccct gaccggcgaa ctggaccagg     10800
     ccaccaccag cgcggtgcgg gtgccgtggc cggccggccc gtcgcacggc gacctgcacc     10860
     tgtcgcacat cctgcgccgg cagacaccgg acggctggcg gctgtgtgtg atcgacctgt     10920
     ccacgcccgc ccccgacccg gccgacccgc tcggcgccgc ccagtcaccg tggcaggacc     10980
     tggtggcgct gctgcgcggg ctggagatct tcaccgccga cgagttcgtg caccaggcgg     11040
     ccctgcggct cggcgccgac caggacgaca cctgccggac cgtgctgctg atcagtgccg     11100
     ggcagacccc ggacacgccg ggttggaccg ggtcccggct caccgcgctg cggcggatgc     11160
     acgacgcggc gtcggtgtgg gccggacagg tccgccggat gctgctgtcc ggttatgccg     11220
     acggcggcga ggcggccgag gagcaccccg cctggcggat cttccggctc cgccgtctgt     11280
     tgcacgaact ggactacgcg tacgcccacg accagcacta ccacgcggcg atcaaccttc     11340
     gacacgtcct ccagacctac cggccgccgg tcaccgggga gagctgagca catgcacatc     11400
     atcgagacgt acttcgaatg cggcggcttc gaccaccggt tcatccaggg cggcacctcg     11460
     gtctatctct ggcagctgtc gcgtggcctg gccgacctgg gacaccgggt ctccatcgtc     11520
     acaccggcgc acggccgcct ggacgatctg cgccggctgc acgaggtcga ggacctgccc     11580
     ggcaccgacg agtacgaact gccgctggtg ctcgacccgc gcgtgtgggg cgaacggttc     11640
     ccggcccaga tggacatcgc cctgcggacc accgcgcatc ggatccggct ggcgggcgtg     11700
     gacctgtact tcctctccaa cgaactgctc gatcagttgc cggaccggtt ctatcccccg     11760
     tacgagagca agggggttga tctggtcttc ttcaagccgc tcgcctatca ggtggcggcc     11820
     atccggttca tcaggtcgca cttcggtgac cagcgcgcga tcgtgcacgc acacgagccg     11880
     ttctaccact acctgatgcc ggccgccttc gccgcggacc cggccaaaca cgtggtcagc     11940
     acggtgcaga gcaacatgcc gatcaacaag tcggtgtacc gggccgaggt ggcgcggctg     12000
     ctcggcttcc tcggcgcccc gaacgcgctg cccgccgacg atccggccgg cagccgttcg     12060
     ccgcacaccg tggcgatgag ccagtaccag cagctgaccc acctgcacta cgaatacccg     12120
     ccggaccacg tgcgggtcta cgacctggtg gccgagcacg ccgaccggat cgacttcctg     12180
     tcgccggggc accgcgacta ctacacctgc ttcgccgaca ccccgttcgc gcagctgttc     12240
     gccaccctgc cggtgtcgcg gacggtacgg cgcaacgcgg acaagacgtt cgtcggcggc     12300
     tgcgccgtcg gtgacgagtg ggtgaccggc gagctgcccc cggtcgaccg ggagaaggtg     12360
     ctggccgggc tcggcctgga cccggacctg ccggccttct accacaacgc ccggtacgcg     12420
     gtcaaccaca aggggcaggt cgagctgatc cgggccgtcg accgggtgct gagcggcggc     12480
     gtgcgggcca gcttcatcgt gcgctgcctc agcgacgccg ggatcgccga cccgctcttc     12540
     cacgaggtgg tggcccgcca cccgggccgg gtgaatctgg agtggcaccg ggtgccggag     12600
     gaccagctgc gggagtacgc ccgagccgcg gacttctgtc tcttcccgtc caagttcgag     12660
     atggacacct tcctgatcgc ccagggtgag gcgatggctg ccggtgcggt accgatcgcc     12720
     accgcccagc tggggatggc gcacttcggt cacgtcgccg acccgctgac cgggccggac     12780
     gcggcgacgg ccaccggatt cgccgtcaac cgctcgttcg ccgaggacga tccgctgctg     12840
     gtccagggcc tgaccgagca gatccgccgg gccgtcacgc tctggaacga gcagcccggc     12900
     cagtaccgcc ggttgtccgc caacgccgtc gcccgggccc gcgagttcac ctggcggcgg     12960
     gcggcccagg cgcacgaggc cgcgttcgcc ggggtgtggg ccggccgtac cccccgcctg     13020
     ccggtcggtg acctgctgcg gttcggctgg ttcgacgagc tgcccgcgga cgcctggacg     13080
     ctgcaccgcg acgagatcgc ggaggtggcc ctggcccacg gcgacgccga cgcctacctg     13140
     cgctgccggc ccgacgacct cgacgccctg gcggcactct tcgagcgggc ctgggcccgg     13200
     gccgacttcc cggcctgcgc gcggaccgta gagctggccg aggagcaccg gcaggagcgg     13260
     gtgccgcagt ggcgggcccg gctcgccggc cgcggccgca tcgaccgcga cggtcggctg     13320
     cactaccgtc cgccgtccgc cgaacgggtc gaactggtct tgcccgacct ggccgaaccc     13380
     ctgcgcggaa cggtcaccgt gaccgcgatg gctccgaccg gcgacacctt caccggacag     13440
     ctgccggccg gaacccggcg tgccgacctg ctgctcaccc tcagtgacgg gcgcaccgtc     13500
     tgggacgagg tgacggcatg agcacgggcg tacgggcggt gctgctcgcc ggtggtgagg     13560
     gacggcggat gggagcgctc ggcgcgggcc ggctcaagcc gctggtgccg ttcgggggcg     13620
     cggcccggct gatcgacttc agtctggcca atgcccgcga ctccggcctg gaccaggtgc     13680
     tgctgctgtc gcagtaccag gagcggcagc tgatggacga cctgcggcgc acctggtggc     13740
     agccggggtt ccgggtgcac ttcgggccgt acgaccgggc ctacaccgac gggatcccgg     13800
     tggagtacga gccgccgacc gggccaccgg agcggggcac cgcggacgcg ctgatccgca     13860
     aggcccccta cctgttcggg ccggatgtca ccgaggtgct ggtgcagcac gccgatcacg     13920
     tgtaccgctt cgactaccgg ccgatgatcg ccgagcaccg cgcgtccggt gccgcgttga     13980
     ccgtgtccta ccagcggatc gaccgccggt acgtgcacct gttcgggatg gtcgagttcg     14040
     acgaccgtaa ccgtctggtc tcgttcgtgg agaagcccgc cgaaccgacc agcgacctgg     14100
     tgttcgccgc gttctgcgtg ttcgacgccg cggtgctgca ccgctacctg gaactgctgg     14160
     acggcaccga ctggcagcac gacatcagcc gcgacgtcat cccggcgatg ctggccgccg     14220
     gcgagcacat ccgcggctgc ccggtgcccg gctactgggc cgacatcggc accgtcgagc     14280
     gctatcacga ggcccacctg tcgctggtgg gcacaccgcc gtcgctggcc gtcgacgcca     14340
     tgccgtggac cgtggcgccc cggaccgccc gggcactggt gacctcggcc gacggtgtgc     14400
     ggcacagtgt cgtaccggcg gacctggtca accacggcac cgtcgagcgc agcgtgctct     14460
     tcccggcggc gcggatcggg cccggcgcga cggtgcgcga cagtgtgctg ctgcccggag     14520
     cggtggtgcc ggccggcgcg gagatcgacg gcgccgtggt gctcgaggac ggcaccgtcc     14580
     agcaggtcac caccggagcc cggcgatgac cggcgccgtc cgggccgtgc gatcccgtga     14640
     ggtgtaccgc aacccgtgga tgagcgtgcg cgaggacgac atcgtgcacg ccgacggctc     14700
     gccgggcagc tacggggtcg tcaccaaacc cgattacgcg ctgatcatcc cgcgggacaa     14760
     cggcctgctg cacctggtgg agcagtaccg ctacccggtc ggcgggcggt tctgggagtt     14820
     cccgcagggc tcgtggccgg ccgacgccgc cggcggtgcc gctgacctgc tcgcccgtac     14880
     cgagttggcc gaggagaccg ggctgcgggc cggccggctg acaccgctgg ggcgcatcca     14940
     cgtcgcgtac ggctacgcca gccagggctg tcacgtcttc ctggccgaac agctcacagc     15000
     ggggcgctct cagcgggagc gcaccgagtc cgacatgcgc cagcgtgccg tggacgccgc     15060
     cggctgggcc gacctggtcg gctccggccg gatcaccgac gccgcgacgc tcgcggccta     15120
     caccctgctg cggatgtacg acagcggaac gcgacagccc atgccggaag gagccgaatc     15180
     gtgcacgtgg tgagcttcgc cttcgaagcc ctcgccttcg acgtagggat gatgcgcggc     15240
     gggctcgccc cgctggcctg ggaactggcc cgccactacg ccgcccaggg acaccgctcc     15300
     tcgatcgtca ccccggcgca cggccgcctg ccgtacctcg ccgagcggta cgacctggtc     15360
     gaactcgact accgggacga gcatgtcgtt cccgtggtcc cggaccccga cgtctgggcg     15420
     gggcagcccc gcgaactggg cctgcccctg gtcacccggg cccacctgct gcggcacgag     15480
     ggcgtcgaca tctacctgct cagcgacgag tacctcgatc tgctgccgga gcggctctac     15540
     ccggccggca cgagtgaggg cagcgacctg gcgtacttca aaccgctggt gttccaggtc     15600
     ggtgggctgc gcttcctgca gtcccggctg gccggtgacg agcccgccgt cgtgcaggcc     15660
     tacgagccgt actaccacta cctcctgccc ccggtgctgg ccggcgaccc gcggttccgg     15720
     gtgatgtcca cggtggccag cagcatgccg atcgacctgg gtgtgtaccg gccccaggtg     15780
     gaccgcctgc tcgagcactt cggcgccggc accgacctgg accgctatgt ggagagcccg     15840
     gtcgcggccg gcgccgacca tcccgcggcc acccgcgagg cggcgctggg cgcggcgatg     15900
     gccggatacc tgccgacgac ccggctctcc agcgggcggc ggcgggccga ctacgtgggc     15960
     ctgttcgcgc tgatcaccga ccactgcgac acggtggact tcctgacccc ggggcagcgg     16020
     cggttctact cgacgttccg ggacaccccg tacgaggcgg cgttccggcg gaccgcggtg     16080
     gcccgggtgg tccgggagaa cgcggcgaaa cagttcgtcg gcggctgtgc gctgccggag     16140
     aactggctgc ggcgggaccc ggccgaggtg gaccgggcgg cgtacctctc cgggctcggg     16200
     ctggacccgg cgctgccgac cttctaccac gtgggccggt actcgccgca ccacaagggt     16260
     caggtggagc tcttccgggc ggtcgagcgg atcctcgcca ccgacacccg ggtcaacttc     16320
     gtgctgcgct gcgccacctc ggccggcggc ggcggcgcca ggatcggtga ccccgccttc     16380
     caggcggtgg ccgaccggca ccccggccag gtgcggctct tctggaccat ggccgacgag     16440
     gacgaactgt tcaccgaggc ggtggcggcg gacttcgggt tgttcccgtc caagtacgaa     16500
     ctggacacct tcctgaccgc ccaggggcag ctgtgcgcct gcggcgcggt gccgatcggg     16560
     accgcgcagg agtcgacccg gcactaccgg caccagctgg ccaccgacca tccgctggcc     16620
     accggattcg ccctgccgcg ctccttcacc ccggacgacg aacgtctgac cggcgctctg     16680
     gtgcgtacca tgcgggaggc gctgcggatg taccgcgacg aaccgggcga gtaccggcgg     16740
     ctggccggca acgccgccga actcgcccgc accttccgct acgccgaggt gtcccggcga     16800
     cggctcgccc acttcgcgaa gctgctcgac ggcacgccga cagcggccga cccggagcac     16860
     gtcatcgggt gcggctggtt cgaccagttg gacgccgcgc agtgggcggc ccacctgccg     16920
     cagatccggc gcgaagcgat ccgcctcggt gacctggaga cgctgcgccg ctgcggcccg     16980
     gtcgacccgg gcgcgctcgg cgcactgtac gaggccgcgt accggcgtgc cgacttcgac     17040
     cggtgcgtgc gggtcgcgga actgctgggc gaccggggca gcgaggcggt gtcgctgcgc     17100
     cggcgctgcc gggtacggcc gcacgagcag ggctgggaga tccagtaccg ggcgccgggc     17160
     gccgagcagg tggccctggt ggtcggcggt accgcccacc ggatgcacgg ttcggccggc     17220
     cggttcagca cggtgctgcc cacggtgccg atgccgtcac cggtgttcct gctgacgctg     17280
     gcctccggac ggtacgcgtg ggacgcccca ccggccaccg cacacctcgc cgacctcgcc     17340
     ggtcagccgc acccggcgca gccggtcggg gccgggggcc gctgacatgg acggcatcgg     17400
     caccacaccc ccgcgcgacc accgggtcgt cgcgaccgac ctcgacggca ccctgctgcg     17460
     ctccgacctg accgtgtccg cccggacccg cgcggcgctg cgcgacgccc gggcggccgg     17520
     catgatccac ctcgcggtga ccggccgccc ggtgatcgac acccgccggc tgctcgccgg     17580
     gctgggctac accggcccgg cggtctgcgg tcagggcgcc caggtgtacg acttcggcac     17640
     cgaccggctg ctgctgagcc gcagcctcga caccgacctg gtgcgcgagc tggtgcgccg     17700
     gatcgcgcag cggaccggtc cgctcgcgct ggccgcggtg agcgccggcc tgggcaccga     17760
     gttcctggtc accgccggtt tcggtgcccc ctaccagcag catcgctggc agctcgtcga     17820
     cgagccggac ctgtggcgtg cgccggtcgc caaggtgctg atccggcacc cggaccacga     17880
     cgacgacacg ctcgcggcac tcgccgacga ggtctgcggc gcggcgctgt cggtgatgca     17940
     cgccggtccg ggcctggtcg aactgctgcc cggtgacacc agcaaacgca ccggcctggc     18000
     ctttctcgcc gccgaactgg gcttcaccgg ggccgacacc atcgccttcg gggacatgcc     18060
     caacgacctg ccgatgttcg actgggccgg gtacggcgtc gcgatggcta acggccaccc     18120
     ccggctgcgc gaccgcgccg acgagatcac tgtcagcaac gacgcggacg gcgtggccgt     18180
     ggtgctcgaa cgtctgcccg ccgtccgggc cggaaaccga aaggcaagcc tgcgatgacc     18240
     accacgacgg atgccgcgct gatcgagctg gccggacggt acggggtgtc ggtcgactgg     18300
     accaccgacc gcggcgagcc gcggacggtg ccggccgaca cgatccagcg gatcctggct     18360
     gtgctcggtg tggacgcgag ctccggcccc gcgatcgccg ccgcgctgcg tgccgcggac     18420
     gacgacgccc ggcaccggct gctgccgtcc tgcgtggtgg tgcggcaggg ggaaccggcc     18480
     aggggagtcc acccggtggc cggggccgcc tatgtggtgg cgaccgagga cggtggccgg     18540
     cacgagacgg ccgacccgcg caacgacctc ggccgccttc cgatcggata ccacacgctg     18600
     cgcgtacggg tgggcgaccg gtccgccgcc gcgccggtga tcgtggctcc ggccgtcctc     18660
     ggcaccccgg accggcggca ctgggggatg ctggcgcaga tctactccgt actgtccgaa     18720
     cggtcctggg ggatgggcga cctcggcgac ctggccgacc tgacccgctg gtcggcccgg     18780
     ctcggggcgt cgttcgtgct ggtcaatccg atgcacgcct acgtgccgga ccgcctggcc     18840
     gaccccacgc cctaccggcc gggcagccgg cggttcgccg acccgatgta tctgcggctg     18900
     gccgacgtcg ccgagtacgc gaccgcggaa ccggcggtgc gggccgaact cgaccgggcc     18960
     gcccgtcagg gacacgaact gaccgccgag gtgctgcacc ggaacgcgct gatcgaccgg     19020
     gctcgggtgt ggccggtcaa gcggaacgcc ctggagcggc tctaccgggc accccgcacg     19080
     gccgggcggt ccgcggctct ggccgccttc accgcccgcg agggccgggg tctcgaggac     19140
     tacgccacct ggtgtgcgct ggccgaggtg tacggcaccc gctggcgttc ctggccggcc     19200
     gctctgcaat ccccgcacgg cccggcggtc gccgccgccc gccgcgagct ggtcgaccgg     19260
     atcgatttcc accgctggct ggcctggctc gtcgacgagc agatggccgc ggcccaggcg     19320
     gccgccgtcg ggtccggcat ggcgatcggc gtgatccacg acttggccgt cggcgtcgac     19380
     ccggagggtg ccgacgcgtg ggcggtgcag gatcatctgg ccggcggtgt cacggtgggc     19440
     tgcccggccg acgacttcaa cccgctcggg caggactggg ggttgccgcc gtggcgcccg     19500
     gacaccctgg ccgaagccgg ttaccggccg ttcgccgacg tgatccgcgg caccctgcgg     19560
     cacagcgggg cgctgcggct ggaccacatt ctcggcctgt tccggctctg gtggatcccg     19620
     gccgggagcg gcgcccgcga cggtgcctac gtccgctacg accacgaggc catgctcggg     19680
     gtgctggccg tcgaggcgtt ccgggccggg gcgatgatca tcggcgagga tctgggcacc     19740
     gtccatccgg cggtccgtgc cgaactcgcc gaccggggca tcctcggcac gtccgtgctg     19800
     cgcttcgagt accagggcgg atcggagaac cgcagcgggc cgctgccggc cgaccagtgg     19860
     cgtgccggct gcctggccac cctcaccacc cacgacctgc cgagtacggc cgcctggctc     19920
     agcggtgagc acgtggacct gcaggaccgg ctgggcctgc tgaaccggcc ccgagccgag     19980
     gtggccgccg acgcggcggc cgaacgtgac ggctggctgg ccgagttgcg gcgcaccggt     20040
     ctgctggagc acgagaccgc cgtaccgggg atgagcgccg agtcgctggc cctgcaccgg     20100
     ttcctggccc ggaccccggc ccgcctggtc ggagtgtggc tgcccgacct ggtcggcgac     20160
     cggaggccgc agaacctgcc gggcaccagc accgagttcc cgaactggca gctgccggtc     20220
     gccgacgccg acggccggcc ggtggcgatg gacgacctgg cgtcctcggc cggcgcccaa     20280
     gcggtcgccg gcctgtacgc cgcatcggcc gagccggcca ccacaccctg acctcgctga     20340
     cccgcacctt tcaaggagat ccatgtcgga gcacaccgac gtcctcgtcc tcggcggcgc     20400
     cggcgtcgac accatcgcct acgtgcccga actgccgctg ccgttccagg acagctacgt     20460
     ggtcgcggcc atcgaaccac gagccgggca gaccggcgac aacgtcgctc tcggcctgca     20520
     cacgctgggc ctgcgcacga tgcacgtcga cgtgctcggc gacgacccgg aaggtgacct     20580
     ggtccgggcc ttccacaccc ggcacggtct gccgttcgcc gccctgccca cggccgccgg     20640
     caccaagcgg gcggtgaacc tggtcggccc ggacggccgc cggctgtcgc tgtgggacgg     20700
     cagccgggaa gccgaggagg accgctaccc ggccgccctg atcgccgcgc acaccgccca     20760
     cgcccggcac gtgcacgtct gcatcacccc gcccgggcag cacgtgttcg gccagctcaa     20820
     cgacctgccg gtcaccgtct ccaccgacct gcacaattgg gacggcgcct acgagggctt     20880
     cgaggtctac gccttcaacg ccgacctggt gttcctgtcg gcgaccgcgc tgaccgacgt     20940
     ggccgcgacg atgcgccgcg tcatcgaccg gggccgggcc cggctggtgg tggccaccga     21000
     cggcgcccac ggcggatcgg tgctggtgcg cggcgagacg gaggtccggc ggtacgcggc     21060
     ggtggccccc gaggcgccgg tggtggactc caacggcgcc ggtgacgcgt tcgtgtccgg     21120
     cttcctcttc gggcacctgg ccggcgaacc gctggagacc tgcctgcgct acggcgcgat     21180
     cgccggcgcc tacgcgtgca ccatccccgc cacccgggcc ggcgccatcg accgggccgc     21240
     gctgctgcgg ccggcggcgt gaagcggcca ccgcaccacc cggtcacggt ggccgacgtg     21300
     ggcggcaccc acctgcgctg ggcacggtgg tcaccggacg gcggactggg cgaagtgcac     21360
     accacgccgt ctccggggca cgcccggcgg cccggcgccg gtgccgccga cctgcaggcg     21420
     gaactgatcc gcgagctggc gtcgcgggtc gagccgggtg cgcgggccgg tgtctcgctc     21480
     ggcgcggcca tggaccacca cagtggtacg gcgtacgcct ccgcgccgtt gtggggtccg     21540
     caggtcagcc cgttcgacgt gccggccgcc ctgcgcgccg cccggccgga cgtgcactgg     21600
     accgtggtca acgacgtcac ggcggggctg ctgcacctgg ccgagatggt tcgcgacgcc     21660
     ggcgtccgca aggcgtgcct ggtcacgatc agcaccggca tcgcctgccg gacgatggac     21720
     ctgcgcaccg gcggtatccc ggtcgacgcg gccggcctcc agggcgagat cggtcacctg     21780
     ccggcgaccg tgctggccga cggggtgccg gtggtgaccc gctgcgactg cggtgagccg     21840
     gggcacgtgg cggcgtcctc gtccgggccg ggcattcgac gggtcgcggc cgtcctggcc     21900
     cggcgtgacc cggccacctg ggcgggctcc gggccgacca cccggatgat ggcgggctcg     21960
     ggcttcgagg acgcgttccg ggccgctctg gacgacggcg atccggtcgc ggcggacctg     22020
     ctgacggcgg tgaccgcccc gatcgcggac ctgctgcgga ccgccctctg cctggacccg     22080
     gaactcgacc tgatcgcgct gaccggtgga gtcgcccacg ggctggaacc gcactactcg     22140
     gcggcggtgc acgaccacct gcggcgccgg gggctctacc tgacctccga gcgggagccg     22200
     gactggttga ccgggcggat ccgggtcgtc ccgccggcga cggccgatcc gttggtcggc     22260
     gccggtctgg ccgcactggc ggcggggccg gtcccggcgt actccggtgg tggccgggaa     22320
     gcgttggtcg ggcgatgagc cggcaccgcg cgatcgtgcg caccggcacc ggcgtggtgg     22380
     tcgccgacgt cccgaccccg gtgccggggc cgggagagct gttggtcggc accgagtggg     22440
     cgggactgtg cggcaccgac atccagatgc tgcgcggcct gcgcgacgat cccgaaccga     22500
     tcatcggcca cgaggggatc gcccgggtga tcgcggccgg cgacggcgtg cccggcacgc     22560
     tgcggccggg gaccctggtg gcggtcaacc cgacccaccg ggacgatccg tcgttcctgc     22620
     tcgggcacaa cgttcccggc ctgctgcagg aacggacgct gctgccggcc accgcggtct     22680
     ccggtggctt ggtgctcccg ctgccggacg gcaccgacgt cacgctgggc ccgctgctgg     22740
     aaccgctggc cgtggtcagc tatgcgctga gccagctcgg cgccgtccgc ccggccaccc     22800
     tggtgatcgt cggcgacgga acggtgggtc acctggccgc ccgggctgcg gtgacctggc     22860
     tggcggagcg gccccgggtg gtgctggtgc accacacggc agcggggcgg gacttcagcg     22920
     cggccgggcc gcatccggcg gacgttctgc tcaccaccgg cgagctggcg ggcagaccgc     22980
     tgccgggacc ggtggccgcc ctgctggcga ccccacggga cgcgactgtc gaggccctgg     23040
     aggcggtcct ggccgcggcc ggcgccgatg tgctgatcga cgtgctgggc ggcctgcccc     23100
     cgggcgcgcg atcggcgatg ctgcccggtg tcgatctcac cgccgtgcgg gcggccaact     23160
     gcggcggctt cccggaaccg gctctggtca ccaccacctc cggcggaacc cggctcttcg     23220
     ggcatcgcgg ggtgggcaac gcgcacctgc gggcggcggc cggcgagctg gcccgcgacc     23280
     cggaccggta ccgggatctc gtcacccatc gcagcgatct ggccggcgcg gcccggatca     23340
     tgaccgcgct ccggagcggc cgggaccgga tcatcgacgg ccgccgactg gtgaagctcg     23400
     cgatccaggt caatgtcaga gaggatcatc gatgagcggg actctggtgg gccgccgcgc     23460
     cctggtggtg ggcggaacca cgggcatcgg ccggggcatc gccgacgcgt gggccgcggc     23520
     cggcgccgag gtgaccgtct gtggccgcag cgagccggcc ggcgatggcg ccgccgggtt     23580
     gcactgggag ccgctcgacc tgacccggac cggggaggcc ggtgcgcgcc tggaacggat     23640
     cgccggtgac cgggtcgatc tggcctgctt cgccgcggtc tcctacgggg cccggcgcgc     23700
     cgtcttcgag gacgtggcgg tggacgaatg gcgtacccag ctggacatca acgtgcacgg     23760
     cctgtggctc accctgcggg cggcactgcc ggggctgcgt gccgcccggc ccggcctgtt     23820
     cgtgggcgtc tcgtccgagg tggtctacaa cgccgggccc ggccgctccg ggtacaccgc     23880
     ctccaaggcg gccgcgaagg cgctgctgga gtcggtggcc caggaggagg acgagagccg     23940
     ggtccggatc gtgcaggtgc tgccggccgg gatggtcgat actccgagca tccggcgccg     24000
     tcgcccggcc ggcttcgact acagcgacta catggtgccc gccgatttcg cgcgcaacgc     24060
     gctggaactc gccgccacgg ccggcgccgg ccaccacggg gacagcctgg tggtcgacag     24120
     gggcggcgac tggtggtcgg tgcgcgagcg gatgccggtg tcgcagagcc ggccggtgcg     24180
     gacgtgacct gccgggtggg gctgaccgag tggcggctgg cgccctcggg tgcggcggcc     24240
     atccggctgg ccgcggcggt cggtgccgac gggatccagc tcgacttcgg cggcccgggc     24300
     cgtggcgtgc tggtggacgg cccgggccgt gccgggcagc tgcgggcggt cgccgacgag     24360
     gcgggagtgg acctgctcgc gctggccggc aacctgctca acgacatcgg gctcacgtcg     24420
     cagccggcgg tggtccagcc ggtgctggcc cggctggccg acacggcgac cgagctcggg     24480
     gtgccgctgc tcatcgtgcc cagcttccgg cgcagcgcga tcaccgacgc gatgtccttc     24540
     acccgcacag cagccgccct gcgctgggcc gtgtcgctgg ccgaggcccg gggaatcgtg     24600
     ctggccagcg agaacgtcct gcccccggcg cgggcccggc agctggtcga ggaggtcggc     24660
     tcaccggctt tccggctgct gctggacacc ttcaacccgg tccggtacgg actcgacccg     24720
     gcctggctgg ccaccgagct ccggccgtgg tgggccgacc agatccacct caaggacggc     24780
     ccgccggaca ccgggccgtc gccgctgctc ggtgcgggac agggcggggt gcggcgcacc     24840
     ctgaccgcgc tcagggggag ccccgcaccg gtacgggccc tggtgctgga gaacgactac     24900
     cgcgacggcc acggtgcgcg gctgcgagcg gacctggagt gggcccgccg ggccgcggtg     24960
     aacgcgagag aatccgagaa agggaagctg acgtgagtgg tgtcgagacg gtaggggtgc     25020
     acgcggatgc gcaccgcgac tcgtggcagg tgcgggccca gaagcagatc acctacgagg     25080
     tgcgcttccg ggacgacgtg ttcgggctgg actccaccga cctgctggag gccggggcgg     25140
     acggggccgg ttcacggcgg cggttcgtgg tggtggacag cgccgtcgac gccttgtacg     25200
     ggtcccggat ccgggagtac ttcacccatc acggcatcga tcattcgatc ctggtgatgc     25260
     gggtgggcga gacggtcaag gacttcgaca cggcgggccg catcgtcgcc gcgatggacg     25320
     ccttcggact ggcccgccgc cgggagccga tgatcgtcgt cggtggtggg gtgctgatgg     25380
     acgtggccgg tctggtggcc agcctctacc ggcgcggcac gccgttcctg cgggtgccga     25440
     cgacactggt cggactgatc gacgcgggtg tcggcgcgaa gaccggggtc aacttcaacg     25500
     gccacaagaa ccggctgggt acgtacgccc cggctgatct gaccctgctg gaccgccgct     25560
     tcctggccac cctggaccgg cgccacctca gcaacgggct cgccgagatg ctcaagatcg     25620
     cgctgatcaa ggatgccgag ctgttccagc tgctggagcg gcacgggcgg gtcctgatcg     25680
     aggaacggtt ccagggccgt accggaaccg gtgaccgggc cgccgtccgg gccctgcgcg     25740
     cggccaccca tggcatgctg gaggaactcg gccccaatct gtgggagagc cggctggaac     25800
     gcagtgtcga ctacgggcac acgttcagcc cgaccatcga gatgcgcgcg ctgccggctc     25860
     tgctgcacgg cgaggccgtg tgtgtggaca tggcgctgac cacggtgctg gcgtaccggc     25920
     ggggtctgct cgacgtcgcg cagcgggacc ggatcttcgc ggtgatgacc gccctgggcc     25980
     tgccgacctg gcatccgctg ctcacgccgg aggtgctgga ggcggcgttg caggacaccg     26040
     tccggcaccg ggacgggtgg cagcggctgc cactgccggt ggggatcggg ggtgtcacgt     26100
     tcgtcaacga cgtgacggcc ggccgagctg caggccgccc gcgctgatgc agcaccggct     26160
     cgccgaggac gccctgctgc tgcgcgccct agctcgggcc gcggacgccg atcgccggaa     26220
     gcgaccggcg tccgtccgcc caccggttgc cgtcaggtcc accaggaacg gttggcgcga     26280
     taccacgcga ccgtttccgc gatgccgtcg gtgaaatcga cccgcggccg gtaaccgagt     26340
     tccccggcga ttttcgaata gtcgagagaa tagcgccggt cgtgaccttt gcgatcggtc     26400
     acgaaagata tgcgcgaagc cggggcgccg cacgcctcga ggaggatctc ggtcaattcg     26460
     agattcgtcg cctcccaccc accgccgatg tgatagacct cgcctgcccg gccggcaccc     26520
     agggccaggg cgagaccgcg gcaatggtcg ctgacgtgga gccagtcgcg gatgttgcgg     26580
     ccgtcgccgt agaccggtac gtcgagcccg tcgagcagcc tggtgacgaa cagcggaatc     26640
     attttctccg ggaattgccg gggcccgtag ttgttcgagc agcgggtcac cacgacgtcc     26700
     atcccgtgcg tctggtggta ggccagagcg aggaggtcgg acccggcttt gctcgcggcg     26760
     tacggcgagt tgggcgccag cggatggccc tcggcccacg agccggtgtc gatcgacccg     26820
     tacacctcgt cggtggaaac atgcaggaag cggccgatat ggtggcgtag cgcggcgtcc     26880
     agtagcacct gagtgccgac caggttgctg gccacgaagg ggccggaggc gaccaccgag     26940
     cggtcgacgt gggtctcggc ggcgaagtgc gccacggtgt cgtgccgcgc catcagcccc     27000
     tcgattagac cttcgtcaca gatgtcgccc cgaacgaagc tgaaacgagg gtccgccgac     27060
     gcttcggcga gatttctgag attgcctccg taacccagtt tgtcgacgac cgtaacctgc     27120
     gtcacgggtt gtggtgtggc aatgtcgcca ctgatcaggg aagttacaaa atgggacccg     27180
     ataaagccgg ctccgccggt gaccaagatt ttcatcgccg ggattgtagc aatgccgcca     27240
     atgggtgccc gatgttcggc cgagccattt acggggcttg ctgatatggt cggtcacgtg     27300
     cgcggaatat tgctggccgg gggaaccggc tcacggcttc gaccggtgac ctgggcggtt     27360
     tccaaacaac tgatgccggt ctatgacaaa ccgatgatct actatccgct ggccacgctc     27420
     gtcagctgcg ggatccggga gatcctggtc atcacgaccg agaccgaggc cgcccagttc     27480
     cagcggttgc tgggtgacgg ctcgcagtgg ggcctgcgtc tggagttcgc cgtgcagcag     27540
     cgccccgggg gcatcgccga ggccttcctc atcggcgagg agttcctggc cggtgggccg     27600
     gtggcgctca tgctcggcga caacctgctg cacggggtgg acttccgccc ctgcgtgcag     27660
     cgggcacgcg agacggccgg tgggcacgtc ttcggagtgg cggtggccga cccgtcggcc     27720
     tacggggtgg tcgagttcga cgccgccggg cgggtgctgt ccatcgagga gaaaccggtc     27780
     cgtccccgct cgccgtacgc ggttcccggc ttctacctct acgacgccga tgtggtcgag     27840
     acggcccggt cgctgcggcc cagcgcccgc ggggagctgg agatcaccga ggtcaaccag     27900
     gcctacctgc ggcgcggcgc actctcggtg acgctgctgg gtcggggcgc ggtctggctc     27960
     gacaccggca ccctggccga ctgcatgcgc gcggtcgact acgtgcgcgc catcgacgag     28020
     ggccagggca tcaagatcgg ctgtgtggag gaggcggcct ggcgggccgg tttcctcgac     28080
     accgcgcagc tgcgtgccct cgccgagccg ttgatgagca gcggctacgg acagtacctg     28140
     ctggctctga ccggcgacgg gctcagccgt accccgcagt ggccggcctt gaccgccgcc     28200
     gccgggtgag cggcccgcgg agggtgaccg gcccgggcgg cgaagggccg gccccccgcg     28260
     aggcgaggaa ccggcccggt ccgtggtcgc cgcagcgccg gtcagcggac tccggtcacc     28320
     gacatgagcc ggccttgcgc atcccgctca gtcacataga actgtccgtc accggagggc     28380
     agggcggccg ccgcctggaa cgccgggtac tgccacagtt ccggtgcctg ccgccgctgc     28440
     ttctcggtga ggccgtcgcg ctgcgcggtc agccggatgc tgcgatagtc gccggcgagg     28500
     tcaccgtcga ccaggcgcag cccaccgttc ggggcgtgca cgaggtcgta gacgcgcccg     28560
     tcggtggctg ccccggccgg ttccagcgtg tcgggcgtac cggtctgcca ggcgatcgtg     28620
     tcccggtcca cccgcaccgc gtcggccctg gtcagatcga gtttcgccgg tttcaccacc     28680
     gacggcagca gccgttcctg gacgcccgcc tgcacccaga cctcccggcc cgcgtcggcg     28740
     aactccagcc gctggtcggt cggcagatcc ttggcctcgc cggcgtgcat gatgtagctg     28800
     agaccggtgg ccccggccgc cagcgggatc cggaagaccg caccgaagct gtcgaacgac     28860
     tccggcagca gcggcgcgcc ccagtcggcg gtgggggtgg ccgcaccgtc ccacaggtgc     28920
     aggccccagc cggtgtaatc gccggctgga cgccggtagt gcaggatcgc ggtgttcggc     28980
     gcgggtgcgg gcgccggacc ctggtaggag atggccgggt cgccctggtg cagccagatc     29040
     ccgggtgtct gctggggatt gagcgagcgg tcggcgtcga cgtccttgac accgttggcg     29100
     tcactcacgg tgaaggtgac cttcgtggcg ccgggccgca gtttgaccca ggcgaacggc     29160
     ccgttaggcg ttccgttccc ggtgaacggc tctccctgcg ggttcgagcg cggccgcttc     29220
     gaacgttcgc cggtggcgtg caggcgccag ccgtcgtagt cgccggcggg acgctgatag     29280
     tgcacgacgg cgtagcccgc ctcggcccgc acggtgccga ccggatccgg ctggtggtgg     29340
     tggcggtacg gcctcggcgt cccgggcgac cgccggtact gcacctcggc gccgccggcc     29400
     agtccggtca ggtcgtggaa cacccggtac gggccccgtc cggccgtgcc gatcggctgc     29460
     cacggcccgt taccggcgcg ggcggagaag gtgacggtgg acagcgggtc gccggtgacg     29520
     gcgcggtcag ttcggtgcgg cccggcacga gggtcccggc ccgcgggtgc ggtgatcgtc     29580
     acggcggggg cgccgtccgc cgcggggatc ggtttctcgg cccgataggc caccgccgac     29640
     agcgccggca cggtgatggt gagccggccg tcggcaccgg tggccgccgt ctcgccggtg     29700
     ccgtagagag gctggaagcc gcagcccggg gtgtaggtgt cgaaggtgac ggtctgcgcg     29760
     gtggtcgcgt tgttcaccgc gatcacatac tcggcacgct ggtcgcggtc gatgcgggag     29820
     gcggcgaaga ccccggcgcg gtcggcggcg taccgggtga tctgctcacc gtcacgcagt     29880
     cccgggtggg ccttgcgcac ggcgcccagc tcggcgatgg tgcggtagag cgggtgcccg     29940
     gtgtcgtggt tgtcgctcgc gtgggtcttg tcggtgccga tcaggcggtc gtccaggtag     30000
     tccggtgtcc ggctggcgaa catgtcctgg cgcgagccct tgttcagccg agggcgcccg     30060
     gtgaagccct gctcgtcggc ccggagtaga ccacccggct ggccgcgggt gaggaacatc     30120
     agctcgttca ccagttcgag ccggcacccg cgtttcggat cggagccggc cttgatcaga     30180
     gtggcgatcc ggcccatgtc gtggttccac tcgccgaggt ggcagccggc cggcgtcggt     30240
     cccggccggc ggctgtagag gtcgtccttc gcgtacaggt cctgccaagg ctgctggccg     30300
     gtgccttgcc cgcgcgcgta gctctgggcc gcgccctgga acgggaagtc gagggtcgcg     30360
     ggcaggccgc cccggcggac gaacgtcgag gtgacttcct ggtccttgct ccaggcctca     30420
     ccgaagagga agaagtcacg cttgcccgcc ttgtccgcgg ccttgcccac gccctcggcg     30480
     aaaggccgcc agaacgccag gtcggtggct ttgagggtgt ccagccggta gccgtcgacg     30540
     ccgaaccgcc ggatccagcc ggcgtagatg tcggtcagcc cgtgcagcac ctcgggccgc     30600
     tcggtccaca gatcgtcgag gccgccggtg aagtcgccgt attcggcgtt ctccccgccg     30660
     aaggtggtct cgccccggtt gtggtacatg gtcgggtcgt tgagccaggc gggtgccttg     30720
     gcggtggcgt cggacggctt ctcgaagaac ggccggtggg ggaacgactt ctcgtcgacc     30780
     ttggggaagc cgtgtgtccc gtcggcgtag ttgcggtcct cgaagggacg acccgcggtg     30840
     tcgcggtagg gcgcggttcc cttgtcggcg taggcggtgc cctcggcgtt cttgatcacg     30900
     tcggcggtgt ggttcaccac gatgtcgagg tagatcttca tgccgcgccg gtgggcgagg     30960
     ccgaccagcc gcttgaggtc ctcgttggtc ccgaagtgcg ggtcgacctg ggtgaagtcg     31020
     gtgatccagt agccgtggta gccggcggac gcgttcggac ccgtaccctg caccggcttg     31080
     ttcttgaaga tcggcgtcag ccagatcgcc gtggtaccga gcccctggat gtagtccagt     31140
     ttgtcgatca cgccctggat gtcgccgccg tggtagaagc cggcgtcggt ggggtcgtac     31200
     ccggtggtga gccggtctcc ggtcagcccg ccctgatcgt tgccggtgtc gccgttggcg     31260
     aaccggtcgg gcatcaccag gtagagctgc tcggcgtggg acggccggtc cggcggcgat     31320
     tcggcctgcg cggcccgcgg agccggcagg ccaccggcgg cccccaccag cacgggcagc     31380
     agcgcccgga cgatatgaga tttcagtctt tcatccatcg tggaccctct ctcgcgatcg     31440
     ctgggacgct agcccggcgg gagacgtgcc cgcaagaact tgctgtttta gcaagaagtt     31500
     tcagaaccgg gacggcacgc tgtagcccag atcatagatc gcgatcaggt agttaaaact     31560
     gcagctcaac ggcaattgcg catggtctga ggtcgatgta cttaaagctc tgcgcaagct     31620
     tagggttgaa gtggcggtga tgcatccatc actgtatgcg catctgaatg acgtcttctg     31680
     caagttcttg cagcggtctc cgggccctgc ccttcctcgt catcccttca caaggagaag     31740
     ctcgtgcaac gtcacgccag gcatgccatc gccgcggcgg tagccgtttc gctgctgccg     31800
     ccgtcactgc cggctcatgc cgccggggct tcggccgtgg tgccgtacgc cggtaacccg     31860
     gccagtctca agcaggacct ctgctaccag atcgccaccg accggttcag cgacgggaac     31920
     ccggcgaaca acaatccggg caacgtgccc ggcatgttcg ccgacaagac caagctgaac     31980
     gaccggcagg agtggctcaa atacatggga ggtgacttcg ccggcatcac ccagcggatg     32040
     gagtacctca agaacctggg cgtcggcgcg atctggatct cgccgcacgt cgacaacatc     32100
     aacgttccgg cgaacggcgc caccggttac cacggctact ggccgcgcga cttcaagcgg     32160
     ctcgaagagc acttcggcac cgacgaggag ttcgacgcgc tggtgtcggc ggcgcacgcc     32220
     agcaacatca aagtgatcat ggactggacg ccgaacggca ccaacccgcc gaaccaggcc     32280
     gaggacggcg ccctctacga cgatgggcag ctggtcggca ggtacggggc ggacagtgcc     32340
     gggcacttcc accacggccc ggcgatcggc gacttcaacg atcgctacca ggaccagtac     32400
     tacagcctgg ccgacatcgc cgacctcgac cagcagaacc cgcgggtcga ccagctgctc     32460
     aaggacgacg ccaactactg gatggaccgc ggggtcgacg gcatccgggt cgacgccgtc     32520
     aagcacatgc cgctgagctg gcagcggtcc ttcgccgacg cggtcacctc gcacaagagc     32580
     gcggccatct tcggcgagtg gtacatgggc gaccagtccg atccgctcta cgccgaccag     32640
     gtcaagttcg ccaacaccag cggcatcgcg gccatggact tctacaccaa ccgctcgatc     32700
     cgcgacacct tcgccggcgc cggctcgatg aagtccctgg acgcggcgat caccaagacc     32760
     aaccgggact acctctacga gcaggatctg atcacgttcc tggacaacca ggacacccgg     32820
     cgcttcggga cgctcaacag cgatccggcg gccctgcacc gggcgctcgc cttcctgctc     32880
     accacccggg gtacgccgtg cctgttctac ggcaccgagc agtacctgca caacgacacc     32940
     ggtgagggca gcaacaaggg caaggacccg tacaaccggc ccccgatggc cagtttcgac     33000
     accgacacgg tcgcctaccg ggagatccgc gccctctccg acctgcgccg gtcgaacccc     33060
     gcggtggcct acggggacca ccagcagcgg tggatcaacg acgacgtgta cgtctacgag     33120
     cgccggttcg gcgacaacgt gctgctgacc gccatcaaca agggctcgca cgagtaccgg     33180
     ctcgacgggc tgcgcaccgc gctgccggcc ggcacctatc gcgacgtgct cggcggcacc     33240
     ttcggcggct ccgacctgac cgtcgaggac ggcgacggca ccgaccggtc gaccgtcgcg     33300
     ccggtgctgg gtgccgggca ggtcgccgtc tggtcgtacc gggcgccggt ggacaccgag     33360
     ccccggatcg gcggggtcgg gccggtcgtg acccgggccg gcgccaccgt caccgtcgag     33420
     ggcaccggct tcggctccgg cggaaccgtc gcgatcggcg gagtccccgc gaccgtccag     33480
     cagtggacgg cggaccgtat caccgccacc gtcccggtcg gcgttcccac cggggccgtc     33540
     caggtgaccg tcggcaacgg ctccggcacc agcaacgggt acccgatcac cacccgtacc     33600
     ggaaaaccgg tcccggtgca gttcaccgtt cagaacccgc cggccaccgc gcccggggag     33660
     tcgctctacc tgaccggtga cgtcgccgag ttggggcact ggtcgaccag cccggaccag     33720
     accgcgggac agctgctgcg ggtgccgaac gagtcccggg gcgtcctcgt cgccgacctg     33780
     ccggccgggg cgccggtcga gttcaagttc gtcaaggtcg cggccgacgg cacggtgacc     33840
     tgggagggtg gtgccaacca ccggtacacc gtcccggccg gcggcaccgg cacgaccacg     33900
     ctcacctggc agcgctgacg ccaccgtgcg gagggcccgg ccgtgaccgg gcccgccgca     33960
     ccgggccggg cggtggaacg gccgggacgg tgggcgccgg ccccggcgtg cgcagatcga     34020
     gggctgcgca caccgggggc tgaacggctg gtctggccca gcgccgacgg tccgccgtcg     34080
     gcgagtatct caccttcagg gcgtccccgg acgcctcgcc cggcttctcc accagcgccg     34140
     acggttacca gatcacccct tggtggagcc gagggagagg ccggcgatga actgcttctg     34200
     caggagcagg tagaccacca gggtggggat ggcggcgatc agggccgcgg cggcgatcag     34260
     gttctggttc gagacgaact ggccctgcag gttggccagg gcggaggtga tcgggcggcg     34320
     gtcacccgtg gagatcaggg tgatggccca gaagaagtcg ttgtagatcc acgtggtgag     34380
     cagggtggcc agggcggcca gggccgggcg gcacaggggc atcgtcaggc gccagtaacg     34440
     cgaccacagc gtggcgccgt cgatcagggc cgcctcgtcg atggcggggg gcagggtctt     34500
     catgtaattc gacaggacga agacgcagaa gcccagctgg aacgagacgt tgatcaaaat     34560
     caggccggcg tacgagttgt acagcaggcc gcttccactc agccaggacg gcaggtggac     34620
     ggccaggtag atgcggtaca gcggggtgat gatgacctgc tgggggagca ggttgccggc     34680
     ggtgaacagg atcagcagcg gaatgttgaa ccggaaaccg aggcgggaca acacgtacgc     34740
     cgccatggag gccagcaaca gggtgatcag cacggccggc acggtgacat agacggaatt     34800
     gagaaagaat cgccacatgc cggatcgggt ccacgcatgc gcgaagttgg acagggtcat     34860
     ctggtgcggc agtgacacgt accctgactg attggtctct tcgatcggtc gtaacgcgac     34920
     gtacagcgcg aaaacgatcg gcatcagcca caacaccgcc atgaccagca ggaagagctg     34980
     cgatccggta cgtttcaccg ttcctcccgc cggaatgcct gccacaggaa aagggagatc     35040
     ggcaccagcg agatgaccag cagcaccacg cccagcgtgg agccgaagcc gatccgctgg     35100
     gtttccccga cgatgttctg ggtgaccgcc acggacagca gttcgaggcc gcgcagcgga     35160
     ttgccgttgc tggtgatgta gaccaggtcg aaggcccgca acgactcgat gaccgtcacg     35220
     accagcacca cgatgttgat cggtcgcatc gccgggaaga cgacccgcca gaatgtctgc     35280
     cacgcgttcg cgccgtccac gatcgccgcc tcgcgcagcg ccggatcgac cgctttcaaa     35340
     cccgccagat acagcaccat cacgtacggg gcctgccgcc agctcgcctc gacgagcagc     35400
     gcccagaggt tgagccgggg attgccgagc cagtcgatca ggttgtcgtt gtggttgtgc     35460
     ccgagcaccg tgttgatcag cccgaagttg ggggagtaga tgagctccca gatgatgccg     35520
     atcagcgcga gcgacagcat caccggcagg aacagcacgc tctggtagaa ccggctgccc     35580
     cgcaccccgc ggtcgatcac caccgcgaac agcatgccca gcggcgtcgc gaggaggatg     35640
     aagaccacga gccagatggc gttgtgccgg accgccggcc agaagtccgg ataattggtg     35700
     aacgcctggc gataattgtc gacgccgttc aggcaacccg gttgcgggat gccgggcgcg     35760
     gacgggaaat ccgcgcagga ccgcatccgg atcgagccga tcccggtcca tttggtgaag     35820
     gacagcagca cggaggcgag cgccgggaac cagatgaagg cgaggtcgag cagtagcggc     35880
     acgccgagca tggcggcggc gaccgcgacg tcgcggcggg tgagcgtgcg gcggcgccgg     35940
     cgggcggccg gcgccggtcg aatggtcggg gtcatcagcg gaaaatcgtc ttcgcctggt     36000
     cctcagcgct cttctgaacg gtcgcgatcg tctccggggt cggctggtcg atgaactgct     36060
     ggatcagctt gatcatcgcg ttggccatgt cgggcacggt gtcgcggtcc atgaactgcg     36120
     agacgctctt gcatttgccg atctcggcga ccgacttctt ctggatgtcg ttgtaggtgg     36180
     gtgcgatcag cccgttggcc aggccgacgt cccagtggtc ggtcttgagg aacgcggcct     36240
     cggcctcggc ggtgccgatg tattgcagga ccttcttggc cgcggcggcg ttcttcccct     36300
     tcttcggcag gatgaagccg tcggtgggtg cgtccatgta gtcggtgccg tactgcgggt     36360
     tgatcgccgg gaagacgaag aagtccaggt cgggaaggtt cttcgcgctg tagttggcgg     36420
     ccacctggtt ggagccctgg aacatcatcc cggcctgctt gttctccaga gctttggcgg     36480
     cgtcctgcca ggtccggccg ttggcgccct tctgctggta cgcggccagt tcccgccact     36540
     ggtcgaagac cttggtgacc ccggggtcgg tccacggcac ctcgtgcttc atcagcttga     36600
     tgtggtagtc gtagccgttg atccgcaggt tgaggatgtc gaaggtgccc agcgccggcc     36660
     agccgtcctt gtcggcgaag gccagcggga ccagtccgtc cgactgcatc ttccgggcca     36720
     gcgcgatgaa cgcctcccag ctggccggga cctcgtaccc cttggactgg aaaacgctct     36780
     tgttgtagaa gacgacccac gggtagttgt agagcggcac caggtagtag tggccgtcga     36840
     gtcctttgga gaggcttttc gcggcgtcgt tgaaggtgcc gccgatcttg tcccagacgt     36900
     cgtcgatcgg ggtgagcagc ccctgcgcgg cgaagaactg caggcggtac ccggcgaacc     36960
     aggtggccag cgagtccggg gtgccctgca ggtaattgct gatgttgttc tggaacgtgt     37020
     tgtggtccgt ggtgttgacc gtgaccggga cggtggtgct ggtggtcgcc tgctgcatca     37080
     gcgacgcgaa ggccgccttg ggcgcctcgt cggagtagtt ggagccgaac gtgatcggcc     37140
     cgttgccgtc gctgacgctg gtcgtcccgc tcttgtcgtc actgccgcag gcggcgagca     37200
     gggtggcggt cgcggcggcg ccggtgagtc ctatcaggga ccgccgggtc aggccggcgg     37260
     agtcgaaacg tgtcatgggt cgccctccga gctagcggaa acgcacacag tccaacgtga     37320
     ctggccgtca tcgaactctg tcggacggtc gatgtcaaga catccgattg ttactgcctg     37380
     attgcggaaa gatcgtggct cgctggttgc ggggatggcc agggatagtt catgccttac     37440
     agggacatcg acgctgacgg atgcgttgac ccaagatccg acattgtcgc gcgtaatcac     37500
     acgcagggga gtggcacatg cgtcacttgc tcatggtcgc ggtcaccgcg gccgccatcg     37560
     gcaccctcgc cgcacccgcc ccggccgccg cggccaccac cgtcgccctc aacggcggca     37620
     tcgtcggccg cgccttcgac ggcgtcggcg cgatcagcgg tggcggcggc aactcccggc     37680
     tgctcatcga ctacccggaa ccgcagcgcg ggcagatcct cgactacctg ttcaagccgg     37740
     gctacggcgc cgcggtccag ctgctcaaac tggagatcgg cggcgacgcc aactccaccg     37800
     acggctccga gcccagccac cagcacgtac gcggcgacat caactgcaac gccggctacg     37860
     aattctggct cggcgagcag gcggtcgccc gcaaccccgg gatccggctg gtcgccctgc     37920
     cgtgggccgc gcccggctgg atcggcggcg gttccttctg gtccacggac atgatcaatt     37980
     acgacgtctc ctggctcaac tgcgccagac agtacggcct gacgatcagc tacctgggcg     38040
     gctggaacga acgcggccac gacagcacct ggtacaagaa cctgcggacc gggctcgaca     38100
     acgccggata ctccgcggtg cagatcgtcg gcgacgacag cggctggggg atggccgacg     38160
     agttcgccgc cgaccccacg ttgaaaaacg cggtcggcgt gctcggcaac cactacgtct     38220
     gcggctatct gtcccaggcc gactcgtgca gcaccacggg caacgcgcgc tccagcggga     38280
     aaccactgtg ggccagcgaa ttcggctccc aggacgacaa cgcgggcgtg gtgccgtaca     38340
     tccgtaccgt caaccggggt tacctcgacg cggagatcag cggatacatg aactggccgc     38400
     tgatcgcggc catcaccccc aatctgccgt tcgccacggt gggcctgatg gatgccggct     38460
     caccgtggtc gggggcctat cgggtgggcc ggaatctgtg ggcgaacgcg cattacgccc     38520
     agttcaccca gcccggctgg cactatctca acagttcggc cagcggatac ctgggcggga     38580
     accgggccaa cggcagctat gtgacgctca aatcgacgaa caacaccgac tacagcacca     38640
     tctacgagac cagtggcagc accgcggcgc aaaccgtgaa cgtcaccgtc tccggtgggc     38700
     tcagcaccgg caccgttcac gtgtggtcga ccgacatggg ctcgtcgaat tccgccgact     38760
     ggttcgtccg gcaggccgac atcacgccgg tcggcgcgac gtacaccctc aatctgcagc     38820
     cgaatcggat ctataccgtc accacgacca ccgggcaggg gaaaggcacc gcggcgggtc     38880
     cggctccgca tggtctggcc ctgccgtaca gcgacaattt cgacggatat gcggtccgta     38940
     agctgcccca ctacagcgag gacatgcagg ggtcgttcga aacccgggcc tgctcggccg     39000
     ggcgcggcgg gacgtgcctg cagcaggtcg cgccgctgcg gccgatcaat tggcaggacg     39060
     acagcgacgc cttcaccctt ttcggcgaca ccggctggac caattacacg gtcagcctcg     39120
     acgtgaacat gcagcaggcc ggcaccgtca cgctgctggg ccgggccaac atccagaacc     39180
     gtccgcagaa ccggcaggcc gcctatcagc tgcgcgtcac cgacaacggc ggctggtcga     39240
     tcgtcaaaca caccaatgcc gacacggaca cgacgctcgt ctccggcacc cgcgccgcgc     39300
     tgggcctgaa cagctggcac aatctacgac tcggattctc cggcggccag atcaccgccg     39360
     ccatcgacaa caccacggtg ggcaccgtca ccgactatgc gtacggcgcg gggcaggccg     39420
     gcgtcggcgt cgtcggctac cagaccgacc agttcgacaa cctcagcgtc acccccaaca     39480
     gcggcccggc cctcaacacg ctgcgtggcg tcgaatccgg ccgctgtgcc gacgtgcccg     39540
     gcgccagcca gaccaacggc acccagctcg ccctctggga ctgcaacggc ggcagcaatc     39600
     agaacttcac cctgacagat cagaaacaat tgctggtgta cgggtcgaag tgcctggacg     39660
     tcaacgccgg aggaaccgcg gacggcgcca aggtgcagat ctgggattgc cacggcggaa     39720
     ccaaccagca gtggacgctc aacgccgacg gcacgatcgt cggaatcggc tccggcaaat     39780
     gcctggacgc caccggccac ggcacggcca acggcaccct gctcgaaatc tggacctgca     39840
     acggcggcga caaccagaag tggagccggt catgaaacgt ctcgcggccc tgctgtcgat     39900
     cggcattctc ggcctggcgc tcgccgcccc ggcgcaggcg gcggaatcca acggcggcgt     39960
     ccgggtgatg ccactgggcg actccatcac cgacggctac aacgtgcccg gcggctaccg     40020
     catcggactg tggcagcgcc tggccgccga cggccacctc accgacctcg tcggctccgg     40080
     ctccaacggc ccggccggcc tcggcgacca cgaccacgag ggccaccccg gctggcgcat     40140
     cgaccagctc gacgccgcca tcgtcggctg gatccagcag gccgacccgc gtaccatcct     40200
     gctgcacatc ggcacgaacg acatcggcca gaactacgac gtcgccaacg ccccggcccg     40260
     gctctccgcc ctgatcgaca agatccgcgt caacgcgccg caggtgcagc tgttcgtcgc     40320
     gcagatcatc ccgaccgcca acgcggcgaa cgagcagaag acccagacct tcaacgcggc     40380
     cctgcccggc atcgtcgccc agaagggccc gctcacccac ctggtcgacc agcactccgc     40440
     actcaccacc gccgacctgg ccgacggcgt gcacccgaac gccgccggct acgacaggat     40500
     ggccgcccgc tggtacgccg ccctgcaatc ggtgcccggc agcctgacca ccctcaccac     40560
     cccgccggtc ggggcgaccg tgctgctgtc caacccgcag tcgagacgct gcctggacgt     40620
     cggcaccacg gtctccctct gggactgcca cggcgcggcc aaccagcagt gggtccgcac     40680
     cgccgccggc gaactccgca acggcgccga ctgcctggac gcgaccggcg ccggcaccgc     40740
     gaacggcacc aggctgatca tctggccctg ccacggcggc gccaaccagc acttcacctt     40800
     ccaccccgac ggcaccatcg tcggcgtgcc ctccggccgc tgcgtcgacc tcaacgccaa     40860
     cggcaccgcg aacggcacga tcgtccaact gtgggactgc aaccggggcg ccaaccaggt     40920
     gtggtccgcc cgctgaccgg ccccgtgacc ccggtcgtga tctccggggt tccgggcgcg     40980
     ggaagtgatc ggcccggcgc tcgccggccg ggccgggaca agaccggtcg cagcatgctg     41040
     cgaccggtgc gggcgtgcgg cagatcgccc gtcatccggc cgggatcaat cacgggagga     41100
     ggcagcgcag cgccgcccgg tccgcggagt gcggcggcga tcgcctccgc cggagtcgtc     41160
     gtcggccgtc cgatcaggcg ccgcaggtcg ccggagtcgg tgaacatctc gtcgtggctc     41220
     atggcgcggt cggcgtccgc aaggacctgc gccagctcgg tgggcacgcc cgcgccgacc     41280
     agcacccggg cgaacgcgtc gaccggcaga tccgatatct cta                       41323
//