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EBI DbfetchID X90711; SV 1; linear; genomic DNA; STD; PRO; 15389 BP. XX AC X90711; XX DT 19-SEP-1995 (Rel. 45, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 10) XX DE Bordetella pertussis lipopolysaccharide biosynthesis locus baf gene, waaA, DE waaB & wlbA,B,C,D,E,F,G,H,I,J & L genes XX KW baf gene; lipopolysaccharide biosynthesis; terminal inverted repeat; KW waaA gene; waaC gene; wlbA gene; wlbB gene; wlbC gene; wlbD gene; KW wlbE gene; wlbF gene; wlbG gene; wlbH gene; wlbI gene; wlbJ gene; KW wlbK gene; wlbL gene. XX OS Bordetella pertussis OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Alcaligenaceae; Bordetella. XX RN [1] RX DOI; 10.1046/j.1365-2958.1996.354877.x RX PUBMED; 8821935. RA Allen A.G., Maskell D.J.; RT "The identification, cloning and mutagenesis of a genetic locus required RT for lipopolysaccharide biosynthesis in Bordetella pertussis"; RL Mol. Microbiol. 19(1):37-52(1996). XX RN [2] RP 1-15389 RA Maskell D.J.; RT ; RL Submitted (10-AUG-1995) to the EMBL/GenBank/DDBJ databases. RL D.J. Maskell, Imperial College of Science, Technology, and Medicine, Dept RL of Biochemistry, Exhibition Road, London SW7 2AY, UK XX RN [3] RA Reeves P.R., Hobbs M., Valvano M.A., Skurnik M., Whitfield C., Coplin D., RA Kido N., Klena J., Maskell D., Raetz C.R.H., Rick P.D.; RT "Bacterial polysaccharide synthesis and gene nomenclature"; RL Trends Microbiol. 49:495-503(1996). XX CC Polysaccharide genes have been named in accordance with the CC Bacterial Polysaccharide Gene Nomenclature scheme XX FH Key Location/Qualifiers FH FT source 1..15389 FT /organism="Bordetella pertussis" FT /strain="BP536" FT /mol_type="genomic DNA" FT /note="LPS biosynthesis locus" FT /db_xref="taxon:520" FT CDS <1..92 FT /codon_start=3 FT /transl_table=11 FT /gene="baf" FT /db_xref="GOA:Q45338" FT /db_xref="InterPro:IPR004619" FT /db_xref="UniProtKB/Swiss-Prot:Q45338" FT /protein_id="CAA62242.1" FT /translation="FGATPQPTYLDSPVLDGLAALAAQGAPTA" FT CDS complement(289..1575) FT /transl_table=11 FT /gene="waaA" FT /note="gene referred to as kdtA in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45374" FT /db_xref="InterPro:IPR007507" FT /db_xref="UniProtKB/TrEMBL:Q45374" FT /protein_id="CAA62243.1" FT /translation="MGRGVYTLALRGLAPLIWLWMWRRARRAGGQWELFAPARFGRAGA FT RAPAPLAAPVWVHAVSLGETRAAQPLVQALLERGLPVLLTHTTATGRAEGERLFGAAIG FT RGQLQQAWLPYDFPGATRRFLARHAPRCGLLMEREVWPNLLAAARAQGVPMALVSARFS FT ASSLRQAGWLGQALREALAGLDRVLAQTDEDGARLCQAGANAYTVTGSLKFDVALPEAQ FT LRVGHAWAGATGRPVIALASTREGEDAMFIEAIGALQAHRAATPRPLILLIPRHPQRFD FT EAAAQLQAAGLAYARRSAGSGEPGPHIDVLLGDTLGEMPFYYAAADVAIVGGSFARLGG FT QNLIEACAAGTPVIVGPHTFNFKDAARDAIAAGAALRAPDARTALDWALQLLAEPARRQ FT AMSEAARAWTAAHAGATRRTLDALEDWLG" FT CDS complement(1577..2584) FT /transl_table=11 FT /gene="waaC" FT /note="gene referred to as rfaC in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45375" FT /db_xref="InterPro:IPR011908" FT /db_xref="UniProtKB/TrEMBL:Q45375" FT /protein_id="CAA62244.1" FT /translation="MPNRILIVRTSSLGDLVHMLPAISDIARYVPDTQIDWVAEEAFAD FT IPKWHPAVNEVIKVAHRRWRKAWWSEPVRQERRALAERLRSVSYDVVLDMQGLLKSAWL FT VRQTRGVRHGLDWRSAREPLVSLFYNVRHRVEFWQPAVVRQRKLAALTFGYNYAGSPDF FT GLQAFGRAAQADDAPADPGRRMLHLAADRGYAVIMPSASRDDKLWPEDDWRAVFRRLQD FT AGCALRLLAGNEQEAERARVLVAGMEGVEVLPRMDLTSVAQVLAGARLMVGLDSGLTHL FT SAALGRPTIGIYRASTPVRTPLVGPSYTASLGDRGASPSREAVLASVEQALAAA" FT CDS 2714..3766 FT /transl_table=11 FT /gene="wlbA" FT /note="gene referred to as bplA in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q79H45" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q79H45" FT /protein_id="CAA62245.1" FT /translation="MSSLPITDRKIRFGLVGCGRISKNHIGAIAQHGDRAELVEICDTN FT PEALQAAEAATGARPFSSLSDMLAQGNADALVLATPSGLHPWQAIEVAQAGRHVVSEKP FT MATRWEDGKRMVKACDEAGVRLFVVKQNRRNATLQLVKKAIEQGRFGRIYMVTVNVFWT FT RPQEYYDAARWRGKWEWDGGAFMNQASHYVDLLDWLVGPVESVYAYTATLARRIEAEDT FT GVAALRWRHGAMGSINVTMLTYPQNLEGSITILGEKGTVRVGGVAVNRIDEWKFAEPHP FT DDDKIREANYETTSVYGFGHPLYYDNVINCLRGDCEPETDGREGLQSLALLTAIYRSAR FT DGVRIPLPLD" FT CDS 3770..4345 FT /transl_table=11 FT /gene="wlbB" FT /note="gene referred to as bplB in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q79H46" FT /db_xref="InterPro:IPR018120" FT /db_xref="UniProtKB/TrEMBL:Q79H46" FT /protein_id="CAA62246.1" FT /translation="MTTIHPTAIVDEGARIGANSRIWHWVHICGGAEIGAGCSLGQNVF FT VGNRVRIGDRVKIQNNVSVYDNVFLEDDVFCGPSMVFTNVYNPRAAIERKNEYRDTLVR FT QGATLGANCTIVCGATVGRYAFVGAGAVVNKDVPDFALVVGVPARQIGWMSRHGEQLDL FT PLAGNGQARCPHTGDLYILENGVCRLGE" FT CDS 4349..5449 FT /transl_table=11 FT /gene="wlbC" FT /note="gene referred to as bplC in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45378" FT /db_xref="HSSP:1MDX" FT /db_xref="InterPro:IPR015422" FT /db_xref="UniProtKB/TrEMBL:Q45378" FT /protein_id="CAA62247.1" FT /translation="MQFIDLKTQYQALRDTINPRIQAVLDHGQFIMGPEVKELEAALCA FT YTGAKHCITVASGTEALLISLMALGVKAGDEVITTSFTFVATAEVIALLGAKPVFVDVE FT PDTCNIKVSEIEAKITPRTKAIIPVSLYGQCGDMDEVNAVAARHGLPVIEDAAQSFGAT FT YKGRKSCNLSTIGCTSFFPSKPLGCYGDGGALFTNDDELAQAMREIRVHGQSGRYYHAR FT IGVGGRMDTLQCAVVLGKLERFDWEIAQRIKIGARYQQLLADLPGGACTVTVRPDRDSV FT WAQFTVMVPNREAVIAQLKEAGIPTAVHYPRPIHAQPAYEQYAEGAGATPVSDDLAARV FT MSLPMHPDLDEATQDKIVAALRQALN" FT CDS 5457..6545 FT /transl_table=11 FT /gene="wlbD" FT /note="gene referred to as bplD in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45379" FT /db_xref="HSSP:1O6C" FT /db_xref="InterPro:IPR003331" FT /db_xref="UniProtKB/TrEMBL:Q45379" FT /protein_id="CAA62248.1" FT /translation="MPKKILTVLGARPQFIKASVVSAAIAQHPELTEVVVHTGQHFDAN FT MSDVFFDELGMQTPAHQLDIHGGGHGDMTGRMLVALEQVMQAEKPDVVLVYGDTNSTLA FT GALAAVKLHIPVAHVEAGLRSFNLRMPEEVNRILTDRISRWLFTPTDSATRHLAAEGQS FT GEKVVQVGDVMYDVALHHGARVTAEGRALAAHGLKPGGYVLATIHRAENTDDAQRLTTI FT VRALQALAAERQVVWPLHPRTWGILARLGLLDELASTVTLLEPVGYLDMVQLEKYAALI FT ATDSGGVQKEAFFHRIPCVTLRDETEWTELVDAGWNRLAPPVSSAVVAQAVQDALREQP FT RDVQPYGDGQAARRIVDALAAH" FT CDS 6616..7827 FT /transl_table=11 FT /gene="wlbE" FT /note="gene referred to as bplE in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45380" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q45380" FT /protein_id="CAA62249.1" FT /translation="MEFRPYYFGREWIGHGHQVKVAASTISHIRARAPQAGGRLTRENV FT DGIEYLWYATLPYQGNGARRLLNMLQFSARLYGLRRDLGGWRPDIVIASSTHPYDVLPA FT ARLARQTGARLVFEVHDLWPLTPRLLGGFKAWHPMIASMQYAEDYAYRHADLTVSMLPC FT ALPYMRERGLDPRRYAHVPNGVPVTEYSSPDFDNPDYLRVRAQIRQLREQCDFVLAYAG FT THGHANALDMLLQAMARLRDQPIGLLLLGDGPDKPELKRLAGQLGLRHIAFADPVPRPA FT VQAVMADIDAAYIGLRRSPLFQFGVSPNKLFDYMLSACPVVQSIESGNDIVADARCGLS FT VPAEDPAALAAALHGLRTLPAAERQAMGRRGRDYVLARHDYPVLAQQFLDAVQSVTPRR FT AASR" FT CDS 7890..9077 FT /transl_table=11 FT /gene="wlbF" FT /note="gene referred to as bplF in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45381" FT /db_xref="HSSP:1MDO" FT /db_xref="InterPro:IPR015422" FT /db_xref="UniProtKB/TrEMBL:Q45381" FT /protein_id="CAA62250.1" FT /translation="MSDFLPFALPDIGEAEIQAVTESMRSGWLTTGPNAREFEREFAAY FT IGADVEAVAVNSATAGLHLALEAIGVGPGDEVITTTHTFTASAEVARYLGAEPVLVDID FT PATLCISPAAIERAITPRTRAIVPVHYGGLSCDMDSILEIARKHGLKVIEDAAHALPAS FT WQGRRIGSLESDLTVYSFYATKTLATGEGGMVVTRDPALAKRCRVMRLHGIDRDAFDRF FT TSKKPAWYYEIVAPGFKYNMTDTAAAMGRVQLQRVQQMRDRRAQIAAAYDQAFADLPLT FT LPPGPGRTPGVERVAHRDDDEHSWHLYAIRIHPQAPLKCDDFIVRMTENGIGCSVHYVP FT LHLQPYWRDRYGLTPDMYPHSQAAFEGMASLPIYSRMTDADVQRVIASVRQLLRP" FT CDS 9074..9667 FT /transl_table=11 FT /gene="wlbG" FT /note="gene referred to as bplG in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45382" FT /db_xref="InterPro:IPR003362" FT /db_xref="UniProtKB/TrEMBL:Q45382" FT /protein_id="CAA62251.1" FT /translation="MIKRLFDVVCSGLGLLALLPLLALIAIAIKLDSPGPVFFRQERVG FT KDGVPFRIHKLRSMSVRQDPQAGQITVGADPRITRVGKWIRKWKLDELVQLIDVFTGSM FT SLVGPRPEVPRYVVLYPDALRDLVLSVRPGITDPASIRFRNENEILGQSSDPERTYREI FT ILPEKLRIQAEYVQTRTFLGDLKIIAHTLLAVAR" FT CDS 9863..11035 FT /transl_table=11 FT /gene="wlbH" FT /note="gene referred to as bplH in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45386" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q45386" FT /protein_id="CAA62255.1" FT /translation="MLSNVPSRQSPDFAQRTPARVALLGPARSIHTIRWANGLALRGLQ FT VHLLSLETPDLSLYDERIVQYRLPWRAPLGYFLAAPRLRALLKRIDPDLLNVHYATGYG FT LLARRARFSPVLLSAWGSDIYEFPNSSTWHKALLQRNLDHATALAATSHAMQREMRGLT FT RRPIFVTPFGIDEALFQPAQSVQAPAADGPIVIGTVKALETHYGIDTLIQAFALLRQAL FT AASQPGMAERLVLRIYGAGSQLQRLRAQAQAAHIANQVEFKGRIPHAEVPEALRALDVY FT VALSRMDSFGVAILEACSCALPVVVSNADGPAEVVVDGKTGYIVAREDAHAAADRLQEL FT VLNPELRQRLGAAGRARVLSEYTWSKSLDMMLDAYTETARLYRATQPASV" FT CDS 11035..11736 FT /transl_table=11 FT /gene="wlbI" FT /note="gene referred to as bplI in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="UniProtKB/TrEMBL:Q45383" FT /protein_id="CAA62252.1" FT /translation="MTLLPLLVIASYSIIHLLEYLSYYARVAGRMAGKPVTGYAIQNAT FT TTVTRFFYLALMPLLGFLVDKQVPTSLYLQMGLAAMFGAALLSLLGYWLRYSWIALLTN FT AVRKRAGQPPLRVEEIRTALEAPASLPKKRIALLAAIVFLCYCLGVLLSYFFALVFHEY FT RSTISQLSGLINGVATVLLTFVLEPRIAGIVDARPTHDVYHAIQAMLNGRLIAIGLLAP FT ALFFGVCIGFV" FT CDS 11828..12394 FT /transl_table=11 FT /gene="wlbJ" FT /note="gene referred to as bplJ in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="UniProtKB/TrEMBL:Q45384" FT /protein_id="CAA62253.1" FT /translation="MLDPLRPFHFGAALILALIALDREWRRVVLDSALTRWLAATAAVL FT LIQLLWVEHTDRYLRFLAFLLTGVCYTVLADALVRRRVDFAEGLYPIVLYWLITAAIPI FT YDAWTGSGRFRMSYPLTGGVWYNINDMATALVFANLIWLLIKRKLSFPLYLTCWFYALA FT MNRRTILLAASVLGLCCTCWATRGA" FT CDS 12454..13035 FT /transl_table=11 FT /gene="wlbK" FT /note="gene referred to as bplK in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="UniProtKB/TrEMBL:Q45385" FT /protein_id="CAA62254.1" FT /translation="MLHHGNFQFGTLPSLAPRAQVGAGAVLTPASTAAADETIQSAQAG FT EDMPPVGEIGVIANNGDHSTAYRVQLLLDMYAQIREMPWWQWAFGLGLGQLNLMWPATD FT TQWASPHFFWLEMFFHLGLLWVAFLGWLLVRSDSTGRICLITAAIAGMAPSSMIYLQPF FT WFLVGVCVAVLPQKNGAPSRPAALPQHASQ" FT CDS 13084..14958 FT /transl_table=11 FT /gene="wlbL" FT /note="gene referred to as bplL in Mol. Microbiol. FT 19:37-52(1996)" FT /db_xref="GOA:Q45387" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q45387" FT /protein_id="CAA62256.1" FT /translation="MTLPYAIRRLFVDLPRPFKQMLAIVLDAVILLGAFHLALWLRFEL FT FFLTDQYLFLSLLACAGGIAALAAFGVYLYILRYMSERVLAAILGGIVVSVMVVTAGNT FT FLQLATISRGVLVLYAALALVGLIGVRLIARKLLFPADHHMADPRTPVLIYGAGGAGSQ FT LAMALRTGPHYRPVAMLDDDKRKHRLVVNGLRVYPPEQLPKLIDRHNIRQLLIAMPSAP FT PKQIRSIVEAAEPYRLRIRLVPSMRELIDPTNGVRLRDVQVEDLLGRDPVAPIDTLLGR FT CVTDRVVMVTGAGGSIGSELCRQILALRPRKLVLFEIAEPALYAIEQDLRQRIGERNIE FT IAGVLGSVRDAAHCLAQLQEHGVQTIYHAAAYKHVPIVEHNVSEGIRTNAFGTLNMAET FT AIQAGVLDFVLISTDKAVRPTNVMGASKRLAELILQAHAQIQDKTRFSMVRFGNVLGSS FT GSVVPLFRRQILEGGPITLTHPEITRYFMTIPEAAQLVLQAGAMGESGSVFVLDMGEPV FT LIRELAERMVRLYGLTVKNSDQPDGDIEIRITGLRPGEKLYEELLIGEDSRETLHPRIM FT RATEYSLPYETLMGQLRMLDRSLQMCSPRQAAELLGQIVREYASVTYA" FT misc_feature 14955..>15389 FT /note="insertion seqence" FT repeat_region 14955..14982 FT /rpt_type=INVERTED XX SQ Sequence 15389 BP; 2622 A; 5440 C; 4768 G; 2559 T; 0 other; ccttcggcgc cacgccgcag cccacttacc tcgacagccc cgtgctcgac ggcctggcgg 60 cgctcgccgc gcaaggcgcg ccaacggcct gaccccccac acccggcgga tttcccatgc 120 gcatcctgtt cctcctgatc gtcgcggcca acctgtgggt ctatgcgctg ggccagggct 180 ggctgggcct gcgtcccgcc gacgaaggac gcgacgccgc tcgcctgaac caggaaatga 240 aggccgacca ggtcaaggtg ctgcggccct gacgaaccgc acggcgggct atcccagcca 300 atcctccagc gcgtccagcg tgcgccgcgt ggcgccggca tgcgcggcgg tccaggcgcg 360 cgcggcctcg ctcatggcct gccggcgtgc cggctcggcc agcagctgca gcgcccaatc 420 gagcgcggtg cgcgcgtcgg gcgcacgcag cgccgccccc gccgcaatgg cgtcccgggc 480 ggcatccttg aaattgaacg tatgcgggcc gacgatgacc ggcgtgccgg ccgcgcaggc 540 ttcgatcagg ttctgcccgc ccagcctggc gaagctgccc cccacgatgg caacatcggc 600 ggccgcgtag tagaacggca tctcgcccag ggtatcgccc agcagtacgt cgatatgcgg 660 tccgggctcg cccgagccgg ccgagcgccg cgcataggcc aggccggccg cctgcaactg 720 ggcggccgcc tcgtcgaaac gctggggatg gcgaggaatc agcaggatca gcggccgcgg 780 cgtggcggcg cgatgcgcct gcaaggcgcc gatcgcctcg atgaacatgg cgtcctcgcc 840 ctcgcgcgtg ctcgccagcg caatcacggg ccggcccgtc gccccggccc aggcgtgtcc 900 gacccgcaat tgcgcctcgg gcagcgccac gtcgaacttc aggctgccgg tcaccgtgta 960 ggcattcgca ccggcctggc acaggcgcgc gccatcctcg tcggtctgcg ccagcacccg 1020 gtccaggccc gccagggcct cacgcagcgc ctggcccagc cagccggcct ggcgcagcga 1080 cgaagcggaa aagcgcgcgc tgaccagcgc catcggcacc ccctgcgcgc gcgccgccgc 1140 cagcagattg ggccagactt cccgctccat cagcaaaccg cagcgaggcg catggcgcgc 1200 caggaagcgc cgcgtcgcgc caggaaaatc gtagggcagc caggcttgct gcaattgccc 1260 gcgtccgatc gccgcaccga acaggcgctc gccctcggcc cggccggtgg cggtggtatg 1320 ggtcaacagg acgggcaggc cacgctccag cagggcctgg accagcggct gcgccgcgcg 1380 cgtctcgccc aggctgaccg catgcaccca gaccggcgcg gccagcggcg cgggcgcgcg 1440 cgcgccggcg cgaccgaagc gggccggcgc gaacaactcc cactggccgc ccgcgcgccg 1500 cgcgcggcgc cacatccata gccagatcaa cggcgccagg ccccgcaacg ccagggtata 1560 gacgccgcgg cccatgtcag gccgccgcca gggcctgctc gaccgaggcc agcacggcct 1620 cgcgcgatgg cgaggcgcca cggtcgccca ggctggccgt atagctgggc cccaccagcg 1680 gcgtacgcac cggcgtcgag gcacgataga tgccgatggt cggacggccc agcgccgccg 1740 acagatgcgt caggccgctg tccagcccca ccatcaggcg ggcgccggcc agcacctgcg 1800 ccaccgacgt caaatccatg cgcggcagca cttccacgcc ctccatgccg gcaaccagca 1860 cgcgggcgcg ctcggcctcc tgctcgttgc cggccagcag gcgcagggcg cagccggcat 1920 cctgcagccg ccggaatacg gcgcgccaat cgtcctcggg ccacagtttg tcgtcgcggc 1980 tggccgacgg catgatcacc gcataacccc ggtcggccgc caggtgcagc atgcggcggc 2040 ccggatcggc cggcgcatcg tcggcctgcg cggcccggcc gaatgcctgc aatccgaaat 2100 cgggcgatcc cgcgtagttg tagccaaagg tcaacgcggc cagcttgcgc tggcgtacca 2160 cggccggctg ccagaactcc acccggtgcc ggacgttgta aaacagcgac accaacggct 2220 cgcgcgcgga gcgccagtcc aggccgtggc gcaccccgcg ggtctgccgc accagccagg 2280 ccgatttcag cagcccctgc atatccagca cgacatcgta ggacaccgag cgcaggcgct 2340 cggccagcgc gcggcgttcc tggcgcaccg gctcggacca ccaggccttg cgccagcgcc 2400 ggtgtgccac cttgatcacc tcattgaccg ccggatgcca tttcgggata tcggcaaaag 2460 cctcttccgc aacccagtca atctgggtat cgggaacgta tcgggcgata tcggaaatag 2520 caggcagcat atgcaccaaa tcgccaagcg acgaggtgcg aacgatgaga atacgatttg 2580 gcatcaataa ccaacgagat ttgtcaggaa aatccctacg gattcgcggt attattgccg 2640 cttattttcg cccgctgctg tccggggcgg cataagaaga atttcggcaa tttacctcaa 2700 tccctcggcg ttcatgagct cacttcccat caccgatcga aaaatccgtt tcggcttagt 2760 tggttgcggc cgcatttcca agaaccatat cggcgcgatc gcgcagcacg gcgaccgcgc 2820 cgagctggtc gaaatctgcg ataccaaccc cgaggcgctg caggctgccg aggcggccac 2880 cggggcgcgg ccgttctcct cgctcagcga catgctggcg caaggcaatg ccgacgcgct 2940 ggtgctggcc accccgtccg gcctgcaccc ctggcaagcc atcgaagtgg cccaggccgg 3000 tcgccacgtg gtcagcgaga agcccatggc tacccgctgg gaagacggca agcgcatggt 3060 caaggcctgt gacgaagccg gggtgcgcct gttcgtggtc aagcagaacc gccgcaacgc 3120 caccctgcaa ctggtcaaga aggccatcga gcagggccgc ttcggccgta tctacatggt 3180 gacggtcaac gtcttctgga cccggccgca ggagtattac gacgccgccc gctggcgcgg 3240 caagtgggaa tgggacggcg gcgcattcat gaaccaggcc agccactacg tggacctgct 3300 ggactggctg gtcggcccgg tcgaaagcgt ctacgcctac acggccacgc tggcgcgccg 3360 catcgaagcc gaggacaccg gcgtggcggc gctgcgctgg cgccacggcg cgatgggctc 3420 gatcaacgtc accatgctga cctatccgca gaacctggaa ggctccatca ccattctcgg 3480 tgaaaagggg acggttcgcg tgggcggcgt tgcggtcaac cgcatcgacg aatggaagtt 3540 tgccgaaccg catccggatg acgacaagat ccgcgaagcc aattacgaaa ccacgtcggt 3600 ctacggtttc gggcacccgc tgtactacga caatgtcatc aattgcctgc gcggcgactg 3660 cgaacccgaa accgacggcc gcgaaggcct gcaatcgctg gccctgctga ccgccatcta 3720 ccgctccgcg cgcgacggcg tgcgcatccc cctgccgctg gactgacgca tgaccaccat 3780 ccatccgacc gccattgtcg atgaaggcgc ccgcatcggc gccaacagcc gcatctggca 3840 ctgggtccac atctgcggcg gcgccgagat cggcgcaggc tgctcgctgg ggcagaacgt 3900 cttcgtcggc aaccgtgtgc ggatcggcga ccgcgtgaaa atccagaaca acgtgtcggt 3960 gtacgacaac gttttcctgg aggacgacgt gttctgcggt ccgagcatgg tgttcaccaa 4020 cgtctacaac ccgcgcgcgg ccatcgaacg caagaacgaa taccgcgaca cgctggtgcg 4080 ccagggcgcc acgctgggcg ccaactgcac catcgtctgc ggcgcgacag tgggccgcta 4140 cgcctttgtc ggcgccggcg cggtcgtcaa caaggacgtc cccgatttcg cactggtggt 4200 cggtgtgccg gcgcgccaga tcggctggat gagccgccac ggcgaacagc tcgacctgcc 4260 cctggccggc aacggccagg cgcgctgccc ccatacgggc gacctttata tcctggaaaa 4320 cggcgtctgc cgactgggcg agtgagacat gcaattcatt gacctgaaaa cccaatacca 4380 agcgctgcgc gacaccatca acccgcgcat ccaggccgtg ctggaccacg gccagttcat 4440 catgggcccg gaagtcaagg aactggaggc cgccttgtgc gcctacaccg gcgccaagca 4500 ctgcatcacc gtggcctcgg gcaccgaggc gctgctgatc tcgctgatgg cgctgggcgt 4560 gaaggccggc gacgaagtca tcaccacctc gttcaccttc gtggccaccg ctgaagtcat 4620 cgcgctgctg ggcgccaagc ccgtgttcgt cgacgtcgaa ccggatacct gcaacatcaa 4680 ggtgtccgag atcgaagcga agatcacccc gcgcaccaag gccatcatcc cggtgtcgct 4740 gtacggccaa tgcggcgaca tggacgaagt caacgccgtc gcggccaggc acggcctgcc 4800 ggtcatcgaa gacgccgcgc agagcttcgg cgccacctac aagggccgca agagctgcaa 4860 cctgtcgacc atcggctgca ccagcttctt cccgagcaag ccgctgggct gctacggcga 4920 cggcggcgcg ctgttcacca acgacgacga gctggcgcaa gccatgcgcg aaatccgcgt 4980 gcacggccaa tcgggccgct actaccacgc ccgcatcggc gtgggcggcc gcatggacac 5040 gctgcaatgc gccgtggtgc tgggcaagct ggagcgtttc gattgggaaa tcgcccaacg 5100 catcaagatc ggcgcgcgct accagcaact gctggccgat ttgcccggcg gcgcatgtac 5160 cgtaaccgtg cgccccgacc gcgacagcgt ctgggcccag ttcaccgtca tggtgcccaa 5220 ccgcgaagcc gtcatcgccc agctgaagga ggccggcatt cccaccgccg tgcactatcc 5280 gcgccccatc cacgcgcagc cggcctatga gcaatacgcc gagggcgccg gcgccacgcc 5340 ggtttccgac gacctggccg cgcgcgtcat gagcctgccg atgcacccgg atctggacga 5400 agccacccag gacaagatcg tcgccgcgtt gcgccaggcc ctgaactgat ttcgtcatgc 5460 cgaagaagat actgaccgta ctgggcgctc gcccgcaatt catcaaggcg agcgtcgtct 5520 ccgccgccat tgcccagcac ccggaactga cggaagtcgt ggtccacacg ggccagcatt 5580 tcgacgccaa catgtccgac gtcttcttcg acgaactggg catgcagacg cccgcccacc 5640 agctcgacat ccacggcggc ggccacggcg acatgaccgg ccgcatgctg gtcgcgctcg 5700 aacaggtgat gcaggcggaa aagccggacg tggtgctggt ctacggcgac accaattcga 5760 ccctggccgg cgcgctggcg gcggtcaagc tgcatattcc ggtcgcccac gtggaggccg 5820 gcctgcgttc gttcaacctg cgcatgcccg aggaagtgaa ccgcatcctg accgaccgca 5880 tttcgcgctg gctgttcacg cctaccgaca gcgccacgcg ccacctggcc gccgaaggcc 5940 agtcgggcga gaaggtcgtg caggtcggcg atgtcatgta cgacgtcgcg ctgcaccacg 6000 gcgcgcgggt caccgccgaa ggccgggccc tggcggccca tggcctgaag ccgggcggct 6060 atgtgctggc cacgatccat cgcgcggaaa ataccgacga cgcgcaacgc ctgacgacca 6120 tcgtgcgcgc gctgcaggcg ttggccgccg agcgccaggt cgtctggccg ctgcacccgc 6180 gcacgtgggg catcctggcc cgcctgggac tgctcgacga gctggcgtcc accgtcacct 6240 tgctcgaacc ggtcggctac ctggacatgg tgcagctgga gaaatacgcc gccctcatcg 6300 ccaccgactc cggcggcgtg cagaaggaag cgtttttcca tcgcatcccc tgcgtcacgc 6360 tgcgcgacga aaccgaatgg accgagctgg tcgacgccgg ctggaatcgc ctggcgccgc 6420 cggtgtccag cgccgttgtc gcgcaagccg tccaggacgc gttgcgcgaa cagccgcgcg 6480 acgtgcagcc ctacggcgac ggccaggccg cacggcgcat cgtggacgcc ctggccgccc 6540 actgatccac cgtagtacac gcaccgccat gaacatcctg ctgatcaacc attacgcagg 6600 ctcgcccgct atggcatgga gttccggccg tattacttcg gccgcgaatg gatcgggcat 6660 gggcatcagg taaaagtggc ggccagcacg atctcgcaca tccgggcgcg cgccccccag 6720 gcaggcggcc ggctgacgcg cgagaacgtc gatggcatcg agtatctctg gtatgccacg 6780 ttgccgtacc aaggcaacgg cgcgcgccgc ctgctcaata tgctgcagtt cagcgcgcgc 6840 ctgtatgggc tgcgccgcga ccttggcggc tggcggccgg atatcgtcat tgcctcgtcc 6900 acgcatccct acgacgtcct gcccgcggca cgcctggccc gccagaccgg cgcccgcctg 6960 gtgttcgaag tgcacgacct gtggccgctg acgcccaggc tgctgggcgg cttcaaggcc 7020 tggcatccga tgatcgcgtc gatgcaatac gcggaagact acgcgtaccg gcacgccgac 7080 ctgaccgttt ccatgctgcc atgcgccctg ccctacatgc gcgagcgcgg gctggacccg 7140 cggcggtatg cgcacgtgcc caacggcgtg ccggtgacgg aatacagttc gcccgacttc 7200 gataaccccg actatctgcg ggtacgcgcg cagatccgcc aattgcgcga acaatgcgat 7260 ttcgtgcttg cctacgccgg cacgcacggc cacgccaatg cgctggacat gctgttgcag 7320 gcgatggcgc ggctgcgcga ccaacccatc ggcctcttgc tgctgggcga tggccccgac 7380 aaaccggagc tcaagcgcct ggccggccag ctcggcctgc gccacatcgc cttcgccgat 7440 ccggtgcctc gccccgccgt gcaggccgtg atggccgaca tcgacgcggc ctatatcggc 7500 ctgaggcgca gcccgctgtt ccagttcggc gtcagcccca acaagctgtt cgactacatg 7560 ctgtcggcct gcccggtagt gcaatcgatc gaaagcggca acgatatcgt ggccgacgcc 7620 cgttgcggcc tgtccgtgcc ggcggaagat ccggccgccc tggccgcggc cctgcacggc 7680 ctgcgcaccc tgcccgccgc cgagcgccag gccatgggcc ggcgcggccg tgactacgtg 7740 ctcgcccgcc acgactaccc ggtgctggcg cagcaattcc tcgacgccgt gcaatctgtc 7800 acgccacggc gcgcagcctc gcgctaatct gcgagaattg gccggtgccg ccggcggcgc 7860 gcctctcact tctacagcga tccagcacca tgagcgactt cctgcccttt gccctgcccg 7920 atatcggcga ggccgaaatc caagcggtca ccgaatccat gcgttcgggc tggctgacca 7980 ccggccccaa cgcccgcgag ttcgaacgcg aattcgcggc ctacatcggc gccgacgtgg 8040 aggccgtggc cgtcaattcg gccaccgccg gcctgcacct ggccctggaa gccatagggg 8100 tcggcccggg cgacgaagtc atcaccacca cccacacatt caccgccagc gccgaagtcg 8160 cccgctacct gggcgccgaa ccggtcctgg tcgatatcga cccggccacg ctgtgcatct 8220 cgcccgccgc catcgaacgc gccatcacgc cgcgcacccg cgcaatcgtg ccggtgcact 8280 acggcggcct gtcctgcgac atggacagca tcctggagat cgcccgcaag cacggcctga 8340 aagtcatcga ggacgccgcc cacgcgctgc ccgcctcctg gcaaggccgg cgtatcggca 8400 gcctggaaag cgacctgacc gtctacagct tttacgccac caagacgctg gccaccggcg 8460 aagggggcat ggtggtcacg cgcgaccccg ccctcgccaa gcgctgccgt gtcatgcggc 8520 tgcatggcat cgaccgcgac gccttcgatc gcttcacctc gaagaagccg gcgtggtact 8580 acgaaatcgt cgcccccggc ttcaagtaca acatgaccga cacggccgcc gcgatgggcc 8640 gcgtccagtt gcagcgcgtg cagcaaatgc gcgaccggcg cgcacagatc gccgcggcct 8700 atgaccaggc cttcgccgat ctgccgctga cactgccccc cggccctggc cgcacgccgg 8760 gcgtcgaacg cgtggcccac cgcgatgacg acgagcattc ctggcacctg tacgccatcc 8820 gcatccatcc gcaggcgccg ctcaagtgcg acgacttcat cgtgcgcatg accgagaacg 8880 gcatcggctg cagcgtgcac tacgtgccgt tgcacctgca gccctattgg cgcgaccgat 8940 atggcctgac gcctgacatg tacccccatt cccaggccgc attcgaaggc atggccagcc 9000 tgccgatcta ctcgcgcatg accgatgccg atgtacagcg cgtcatcgca tcggtacggc 9060 aactgctgcg cccatgatca aacggctgtt tgacgtcgtt tgctcggggc tggggctgct 9120 ggcgctactg ccgctgctcg ccctgatcgc catcgccatc aagctggaca gcccgggacc 9180 ggtgtttttc cgccaggaac gcgtcggcaa ggacggcgtg ccatttcgca tccacaagct 9240 gcgcagcatg agcgtgcggc aggacccgca ggcggggcag atcacggtgg gcgccgaccc 9300 tcgcataacc cgtgtcggga aatggatccg caagtggaaa ctggacgagc tggtccagtt 9360 gatcgacgtc tttaccggca gcatgagcct ggtcggcccg cgtcccgaag tgccccgcta 9420 tgtggtcctg tatccggacg cgttgcgcga cctggtcctt tcggtgcgcc ccggaatcac 9480 cgatcccgcg tcgatacgct ttcgcaacga aaacgagatc ctgggacaat caagcgaccc 9540 cgaacgtaca taccgcgaaa tcattcttcc ggaaaaattg cgtatccagg ccgaatatgt 9600 ccaaacacgg acatttttgg gtgacctgaa aatcattgcc cataccctgc tggccgttgc 9660 cagataatcg gaaactattt gatactctta ctccacgggt aagacacgcc gctcattgga 9720 gattgtgtta atttgactcg cactcaatgg cgcgccccgg cagtgtcgcg cctttgcgca 9780 ccaacgccgc ggctttcccg ccatccgact gtccccagga tgcgcccggt cgcgcgcacc 9840 cacgatggtt cgatgattta tcttgctaag taacgtaccc tctcgccagt cgccagactt 9900 cgcgcaacgc acgcctgcca gggtagcctt gctgggaccg gcacgtagca tccataccat 9960 ccgctgggca aacggattgg ccctgcgcgg cctgcaggta cacctgcttt cgctggaaac 10020 gcccgatctc tcgctgtacg acgagcgcat cgtccagtat cggcttccct ggcgcgctcc 10080 gctgggttac ttcctggccg cgccccgcct gcgggcactg ctcaaacgca tcgacccgga 10140 tctgctcaac gttcactatg cgaccggcta cggcctgttg gcgcgccgcg cccgtttctc 10200 ccccgtcctg ctgtcagcgt ggggtagcga catttacgag tttccgaact ccagtacctg 10260 gcacaaggca ttgctgcagc gcaatctcga ccatgcgacg gccctggcgg ccaccagcca 10320 cgccatgcag cgcgaaatgc gcggcctgac gcggcgcccg atcttcgtta ccccgttcgg 10380 catcgacgaa gcgctgttcc aaccggccca atccgtccag gcgccggccg cggacggccc 10440 catcgtcata ggcacggtca aggcgctgga aacccactac ggcatcgaca cgctgatcca 10500 ggcctttgcg ctgctcaggc aggccctggc agccagccag cccgggatgg ccgagcgcct 10560 ggtgttgcgc atctatggcg cgggcagcca gctccagcgc ctgcgcgcgc aggcccaggc 10620 cgcccatatc gcgaatcagg tggaattcaa gggacgcatc ccgcacgccg aggtgcccga 10680 agccttgcgc gccctggacg tgtacgtggc cttgagccgc atggacagct tcggcgtcgc 10740 catcctggaa gcctgctcgt gcgccctgcc ggtcgtggtg tccaatgccg atggcccggc 10800 cgaggtcgtg gtcgacggca agacgggcta catcgtggcg cgtgaagacg cccatgccgc 10860 cgccgacagg ctgcaggagc tggtcctgaa cccggagttg cgtcaacgcc tgggtgccgc 10920 cgggcgggcc cgcgtgctca gcgaatatac ctggagcaaa agcctggata tgatgctgga 10980 cgcctacacc gaaacagcca ggctttatcg tgcgacccag cccgcctccg tatgatgacc 11040 ctgctacccc tgctggtcat cgccagctat tcgatcatcc atctgctcga gtatctgagc 11100 tactacgcgc gcgtcgcggg gcgcatggcg ggcaagcccg tcaccggcta tgccatccag 11160 aacgccacca ccacggtcac ccgcttcttc tacctggccc tgatgccgct gctgggcttc 11220 ctggtcgaca agcaggtccc gacctcgctc tatctccaga tggggctggc agccatgttt 11280 ggcgcggcgc tgctgtccct gctgggttac tggctgcgct actcctggat cgcgctgctc 11340 accaatgccg tgcgcaagcg cgcggggcag ccgccactgc gcgttgaaga aatccggacc 11400 gccctggagg caccggccag cctgccgaaa aaacgcatcg ccctgctggc cgcaatcgtt 11460 ttcctttgct attgcctggg cgtattactt tcatactttt tcgcgctggt gtttcacgag 11520 tatcgaagta cgatttcgca actgtcagga ttgatcaacg gcgttgcgac cgtcctgctc 11580 acatttgtcc tggaaccccg cattgccggc atcgtggacg cgcgtccgac ccacgacgtc 11640 tatcatgcga tccaggccat gctgaatggc cggttgatcg caatcggttt gctggcgccc 11700 gctcttttct tcggagtttg cattggcttt gtctagcgcg ccgacccgag ccctggcttg 11760 gccgaacata tccacgccac tggccttgtg cgccgtcgca ctgggttttt ccggctcttc 11820 catctacgtg ctggacccgc tgcgaccctt tcatttcggc gccgcgctga tcctggctct 11880 gatcgcgctg gaccgggaat ggcgccgtgt tgtcctggac agtgccctga cccgctggct 11940 ggcagcgacc gcggcggtcc tgctgatcca gttgctgtgg gtagagcata cggaccgtta 12000 tctgcgtttt ctggccttcc tgctgacagg cgtctgctac accgtgctgg ccgacgcgct 12060 ggtccgccgc cgcgtggatt ttgcggaagg cttgtacccc atagtcctct actggctgat 12120 cacagccgcc ataccgatct acgacgcctg gaccggctcc ggccgcttcc ggatgagcta 12180 ccccctgacc ggcggcgtct ggtacaacat caatgacatg gccacggccc tggtcttcgc 12240 caatctcatc tggctcctga tcaagcgcaa gctgtcgttc cccctgtacc tcacctgttg 12300 gttctatgcc ctggccatga accgccgcac catcttgctg gccgcaagcg tgctggggct 12360 gtgctgtacc tgctgggcta cgcgcggcgc ctgaagcacg gcaaccggac gctgctggcc 12420 ggcgcgctgc ttgcgacctc ggccgccgcc ctggtgctgc atcatggcaa cttccagttc 12480 ggcaccctcc cgtccctggc gccccgggcc caggtcgggg ctggcgccgt actgacgccg 12540 gcatccaccg cggccgccga cgagaccatc caatccgcgc aggccggcga ggatatgccc 12600 cccgtgggcg agatcggagt gattgccaac aacggcgacc actcgaccgc ttatcgggtc 12660 cagctattgc tggacatgta tgcgcagatc cgcgaaatgc cctggtggca atgggcattc 12720 ggcctggggc tgggacaatt gaacctgatg tggccggcga cggacaccca atgggcatcg 12780 ccgcatttct tctggctcga aatgttcttt catctgggct tgctgtgggt ggcattcctc 12840 ggctggctgt tggtgcgctc ggacagtacc ggacgcatct gcctgataac cgcggcgatc 12900 gccggcatgg ccccgagttc catgatttat ctgcagccct tctggtttct ggtcggcgta 12960 tgcgtggccg tcttgccaca gaaaaatggc gccccgtccc gtccagccgc attgccgcag 13020 cacgctagtc agtaaaatcc gcaaactgct tgcctaccct ttttcgcatc gtccgtcgca 13080 gttatgactc tcccctatgc catccggcgc ctcttcgtcg acttgccgcg accgttcaag 13140 cagatgctgg cgatcgtgct ggatgccgta atcctgctgg gcgctttcca cctggcgcta 13200 tggctgcgtt tcgagctgtt cttcctgacc gaccagtatc tgttcctgtc cctgcttgcc 13260 tgcgcgggcg gcattgcggc cctggcggcg ttcggcgtct acctctatat cctgcgctac 13320 atgagcgagc gggtgctggc cgccatcctg gggggaatag tggtatcggt catggtcgtg 13380 accgccggga acaccttcct gcagctggcc accatctcgc gcggcgtact ggtcctgtat 13440 gccgcgctcg ccctggtggg cctgatcggc gtgcggctga ttgcccgcaa actgctgttc 13500 cccgccgacc atcacatggc cgatccgcgc acgccggtac tgatctacgg cgcgggcggg 13560 gccgggtcgc aactggccat ggcgctgcgc acggggccgc attaccgtcc cgtcgccatg 13620 ctcgacgacg acaagcgtaa acaccgcctg gtcgtcaacg gcctgcgggt ctacccgccc 13680 gagcaactgc ccaagctgat cgaccgccac aacatccggc agctgctgat cgcgatgcct 13740 tcggcgccgc ccaagcagat ccgcagcatc gtcgaagccg ccgaaccata ccgcctgcgc 13800 atccggctgg tgccgagcat gcgcgaactc atcgacccca ccaatggcgt gcgcctgcgc 13860 gacgtacagg tggaggatct gctcggacgc gatccggtcg cgcccatcga cacgctgttg 13920 ggccgctgcg tcacggaccg ggtcgtcatg gtcacgggcg ccggcggctc catcggttcc 13980 gaactgtgcc gccagatcct ggccttgcgc ccccgcaagc tggtgctctt cgagatcgcc 14040 gaaccggcgc tctacgccat cgagcaggat ctgcgccagc gcatcggcga gcgcaacatc 14100 gaaattgccg gcgtgctggg gtcggtgcgc gacgccgccc actgcctggc ccagttgcag 14160 gagcacggcg tacagaccat ttatcacgcc gccgcgtaca agcacgtgcc catcgtcgag 14220 cacaatgtct ccgagggcat acgcaccaat gccttcggca cgctcaacat ggccgagacc 14280 gccatccagg cgggcgtgct cgatttcgtc ctgatctcca ccgataaggc cgtgcgcccc 14340 accaatgtca tgggcgcctc caagcgcctg gccgagctga tcctgcaggc gcacgcgcag 14400 atccaggaca agacccgctt ctcgatggtg cgctttggca acgtgctggg cagctccggc 14460 agcgtcgtgc cgctgttccg gcgccagatc ctggaaggcg ggccgatcac gctcacgcac 14520 cccgagatca cgcgctactt catgaccata cccgaagccg cgcaactggt actgcaggcc 14580 ggcgccatgg gcgaatccgg ctcggtcttc gtgctggaca tgggcgaacc ggtattgatc 14640 cgcgaactgg ccgagcgcat ggtgcgcctg tacggactga cagtaaagaa ctcggaccaa 14700 ccggatggcg atatcgaaat tcgcatcacg ggactgcggc ccggggaaaa gctgtacgaa 14760 gaactgctga tcggggaaga ctcccgtgaa accctgcatc cccgcatcat gcgcgccacg 14820 gaatacagcc ttccgtacga aaccctcatg gggcaattgc gcatgctcga tcgttcgctg 14880 caaatgtgca gcccgcggca agcggcggaa ttgctgggcc agatcgtacg ggaatatgcg 14940 tcggtgacgt acgcctagct gtgaactgtc aataggttgt attcgtccag gttgagtctg 15000 gagatgggta cagcgcgccc gatgccttgg tggggtcgat gccagttgta gcggtcaatg 15060 aagggctgca aggcagcctg tcgttcggct gagctcgtgt agggcctggc gtatgcccac 15120 tcccgtaagc aggtctgcac gaggcgctcg gccttgccgt tggtcttggg ggtgtagggg 15180 cgggtgcgga tgtgacggat tcccagctcc acgcacaccg cccgaaaggt cctggagacg 15240 tagccgctgc cgttgtcggt catcacgcgg tcgatgcgca cgcccagact ggcgtagtag 15300 gcggtggctt ggcgcaggaa ctcagcgcac tgatcgccgc cttcatcgtc gaggatgcga 15360 gcaaaggaca cgcgcgagaa gtcatcgat 15389 // |
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