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EBI DbfetchID X87095; SV 1; linear; mRNA; STD; INV; 2085 BP. XX AC X87095; XX DT 01-JUL-1995 (Rel. 44, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 12) XX DE P.falciparum mRNA for thioredoxin reductase XX KW thioredoxin reductase. XX OS Plasmodium falciparum (malaria parasite P. falciparum) OC Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodium; OC Plasmodium (Laverania). XX RN [2] RP 1-2085 RA Mueller S.; RT ; RL Submitted (05-MAY-1995) to the EMBL/GenBank/DDBJ databases. RL S. Mueller, Bernhard Nocht Inst. for Tropical Med., Dept of Biochemistry, RL Bernhard-Nocht-Str. 74, 20359 Hamburg, FRG XX RN [3] RP 1-2085 RX DOI; 10.1016/0166-6851(95)02476-X RX PUBMED; 8719241. RA Muller S., Becker K., Bergmann B., Schirmer R.H., Walter R.D.; RT "Plasmodium falciparum glutathione reductase exhibits sequence similarities RT with the human host enzyme in the core structure but differs at the RT ligand-binding sites"; RL Mol. Biochem. Parasitol. 74(1):11-18(1995). XX RN [4] RP 1-2085 RX DOI; 10.1016/0166-6851(96)02694-1 RX PUBMED; 8892299. RA Muller S., Gilberger T.W., Farber P.M., Becker K., Schirmer R.H., RA Walter R.D.; RT "Recombinant putative glutathione reductase of Plasmodium falciparum RT exhibits thioredoxin reductase activity"; RL Mol. Biochem. Parasitol. 80(2):215-219(1996). XX FH Key Location/Qualifiers FH FT source 1..2085 FT /organism="Plasmodium falciparum" FT /strain="FCH-5" FT /mol_type="mRNA" FT /dev_stage="gametocytes" FT /db_xref="taxon:5833" FT CDS 207..1832 FT /gene="TrxR" FT /product="thioredoxin reductase" FT /db_xref="GOA:Q25861" FT /db_xref="HSSP:1ONF" FT /db_xref="InterPro:IPR006338" FT /db_xref="UniProtKB/Swiss-Prot:Q25861" FT /protein_id="CAA60574.1" FT /translation="MCKDKNEKKNYEHVNANEKNGYLASEKNELTKNKVEEHTYDYDYV FT VIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHYAGH FT MGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVKYINGLAKL FT KDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSITSDDIFSLKKDP FT GKTLVVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKVKLYMEEQGVMFKN FT GILPKKLTKMDDKILVEFSDKTSELYDTVLYAIGRKGDIDGLNLESLNMNVNKSNNKII FT ADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLFKDSDEIMDYSYIPTSIYT FT PIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRAQKDEYDLDVSSTC FT LAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDNCIGIHPTDAESFM FT NLFVTISSGLSYAAKGGCGGGKCG" FT mRNA 1..2085 FT /gene="TrxR" XX SQ Sequence 2085 BP; 829 A; 236 C; 343 G; 677 T; 0 other; taaagaattc atcaaataaa tatttccaaa ttaatcaact tcattttatt aggatcatca 60 ataaaaatat acattctaag aataatctta ttaactctaa ttcatcttat aatgtttttt 120 ataataaata ttttataaag aacacattcc aaaataaaaa taaactatcc tccatatatt 180 ccaaattaaa cttttccatt aaaaacatgt gtaaagataa aaacgaaaaa aaaaattatg 240 aacatgttaa tgcgaatgaa aaaaatggct acctagctag cgaaaaaaac gaactcacca 300 aaaataaggt cgaggaacat acatatgatt atgattatgt tgtaatagga ggaggtccag 360 gtggaatggc ttcagccaaa gaagctgcag cacatggtgc tcgagtttta ttgtttgatt 420 atgtaaagcc aagtagtcaa ggaacaaaat ggggtatagg tggaacgtgt gtgaacgtag 480 gatgtgtacc aaaaaaatta atgcactatg caggtcatat ggggagtata tttaaattag 540 attcgaaagc atatggatgg aaatttgaca atttaaaaca tgactggaag aaattagtta 600 caactgtaca atctcacata cgttcattaa attttagtta tatgactggt ttgagatcat 660 caaaggttaa atatattaat gggttagcca agttaaaaga caaaaataca gtatcttatt 720 atttaaaagg agatttatcg aaagaagaaa ctgttacagg aaaatatatt ttaatagcaa 780 caggatgtag accacatata ccagatgatg ttgaaggtgc taaagaatta agtattacat 840 ctgatgatat tttttcatta aaaaaagatc caggaaaaac attagtagtt ggagcatcat 900 atgtagcctt agagtgttct ggttttctta attcattagg atatgacgta acagtagctg 960 tgcgttcaat agtcttaaga ggttttgatc aacaatgtgc cgttaaagta aaactttata 1020 tggaagaaca aggagttatg tttaagaatg gaattttgcc aaaaaaatta acaaaaatgg 1080 atgataaaat attagtcgaa tttagtgata aaacaagtga attatatgat actgttctat 1140 atgctattgg aagaaaagga gacattgacg gtttaaattt agaatcatta aatatgaatg 1200 taaataaaag taataataaa attatagctg atcatttaag ttgtactaat attccttcaa 1260 tatttgctgt aggagacgta gctgaaaatg tcccagaatt agcgcccgtg gctataaaag 1320 caggagaaat attagctaga cgattattca aagattcaga tgaaataatg gattattcat 1380 atattcctac atctatatat acacctattg aatatggtgc atgtggatat tcagaagaaa 1440 aagcatatga attatatggt aaatcaaatg tagaagtatt tttgcaagaa tttaataatt 1500 tggaaatatc tgctgttcat cgacaaaaac atataagagc acaaaaagat gaatatgact 1560 tggacgtctc tagtacatgc ttagcaaaac ttgtttgtct aaaaaatgaa gacaatcgag 1620 ttattgggtt ccattacgta ggtcctaatg caggagaagt tacacaagga atggctttag 1680 ctttaagatt aaaagttaag aaaaaggact ttgataactg cataggtatt catccaacag 1740 atgctgaatc gttcatgaat ttgtttgtta ccatatcttc tggattgtct tatgcagcta 1800 aaggaggatg tgggggtgga aaatgtggat aaaaggaaaa tctctccatt aacatttcaa 1860 gcattatata tatatatata atatatatat atatatatat aataaatgca tttatagttc 1920 actgcatttc tccatttttg ttatatatat atatataata tatatgtatt tttattttta 1980 ttttatttta ttttatttta tttttatttt ttttaagata cttttttaaa attataaaga 2040 aaattaaatt tttcaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 2085 // |
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