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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   X83603; SV 1; linear; genomic DNA; STD; INV; 1414 BP.
XX
AC   X83603;
XX
DT   01-JUN-1995 (Rel. 44, Created)
DT   18-APR-2005 (Rel. 83, Last updated, Version 20)
XX
DE   P.falciparum thioredoxin reductase gene
XX
KW   thioredoxin reductase.
XX
OS   Plasmodium falciparum (malaria parasite P. falciparum)
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodium;
OC   Plasmodium (Laverania).
XX
RN   [1]
RX   DOI; 10.1016/0166-6851(95)02476-X
RX   PUBMED; 8719241.
RA   Muller S., Becker K., Bergmann B., Schirmer R.H., Walter R.D.;
RT   "Plasmodium falciparum glutathione reductase exhibits sequence similarities
RT   with the human host enzyme in the core structure but differs at the
RT   ligand-binding sites";
RL   Mol. Biochem. Parasitol. 74(1):11-18(1995).
XX
RN   [2]
RP   1-1414
RA   Muller S.;
RT   ;
RL   Submitted (20-DEC-1994) to the EMBL/GenBank/DDBJ databases.
RL   S. Muller, Bernhard Nocht Inst. for Tropical Med., Dept of Biochemistry,
RL   Bernhard-Nocht-Str. 74, 20359 Hamburg, FRG
XX
RN   [3]
RP   1-1414
RX   DOI; 10.1016/0166-6851(96)02694-1
RX   PUBMED; 8892299.
RA   Muller S., Gilberger T.W., Farber P.M., Becker K., Schirmer R.H.,
RA   Walter R.D.;
RT   "Recombinant putative glutathione reductase of Plasmodium falciparum
RT   exhibits thioredoxin reductase activity";
RL   Mol. Biochem. Parasitol. 80(2):215-219(1996).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1414
FT                   /organism="Plasmodium falciparum"
FT                   /strain="FCH-5"
FT                   /mol_type="genomic DNA"
FT                   /dev_stage="erythrocytic asexual stages"
FT                   /db_xref="taxon:5833"
FT   CDS             <1..>1414
FT                   /codon_start=1
FT                   /gene="TrxR"
FT                   /product="thioredoxin reductase"
FT                   /db_xref="GOA:Q25861"
FT                   /db_xref="HSSP:1ONF"
FT                   /db_xref="InterPro:IPR006338"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q25861"
FT                   /protein_id="CAA58583.1"
FT                   /translation="IGAGSGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNV
FT                   GCVPKKLMHYAGHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFSYMTGLR
FT                   SSKVKYINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELS
FT                   ITSDDIFSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKV
FT                   KLYMEEQGVMFKNGILPKKLTKMDDKILVEFSDKTSELYDTVLYAIGRKGDIDGLNLES
FT                   LNMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLFKDSDE
FT                   IMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRA
FT                   QKDEYDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDN
FT                   CIGIHPTAAEELS"
XX
SQ   Sequence 1414 BP; 532 A; 172 C; 287 G; 423 T; 0 other;
     attggagcgg ggtcgggggg aatggcttca gccaaagaag ctgcagcaca tggtgctcga        60
     gttttattgt ttgattatgt aaagccaagt agtcaaggaa caaaatgggg tataggtgga       120
     acgtgtgtga acgtaggatg tgtaccaaaa aaattaatgc actatgcagg tcatatgggg       180
     agtatattta aattagattc gaaagcatat ggatggaaat ttgacaattt aaaacatgac       240
     tggaagaaat tagttacaac tgtacaatct cacatacgtt cattaaattt tagttatatg       300
     actggtttga gatcatcaaa ggttaaatat attaatgggt tagccaagtt aaaagacaaa       360
     aatacagtat cttattattt aaaaggagat ttatcgaaag aagaaactgt tacaggaaaa       420
     tatattttaa tagcaacagg atgtagacca catataccag atgatgttga aggtgctaaa       480
     gaattaagta ttacatctga tgatattttt tcattaaaaa aagatccagg aaaaacatta       540
     gtagttggag catcatatgt agccttagag tgttctggtt ttcttaattc attaggatat       600
     gacgtaacag tagctgtgcg ttcaatagtc ttaagaggtt ttgatcaaca atgtgccgtt       660
     aaagtaaaac tttatatgga agaacaagga gttatgttta agaatggaat tttgccaaaa       720
     aaattaacaa aaatggatga taaaatacta gtcgaattta gtgataaaac aagtgaatta       780
     tatgatactg ttctatatgc tattggaaga aaaggagaca ttgacggttt aaatttagaa       840
     tcattaaata tgaatgtaaa taaaagtaat aataaaatta tagctgatca tttaagttgt       900
     actaatattc cttcaatatt tgctgtagga gacgtagctg aaaatgtccc agaattagcg       960
     cccgtggcta taaaagcagg agaaatatta gctagacgat tattcaaaga ttcagatgaa      1020
     ataatggatt attcatatat tcctacatct atatatacac ctattgaata tggtgcatgt      1080
     ggatattcag aagaaaaagc atatgaatta tatggtaaat caaatgtaga agtatttttg      1140
     caagaattta ataatttgga aatatctgct gttcatcgac aaaaacatat aagagcacaa      1200
     aaagatgaat atgacttgga cgtctctagt acatgcttag caaaacttgt ttgtctaaaa      1260
     aatgaagaca atcgagttat tgggttccat tacgtaggtc ctaatgcagg agaagttaca      1320
     caaggaatgg ctttagcttt aagattaaaa gttaagaaaa aggactttga taactgcata      1380
     ggtattcacc ccaccgccgc ggaggagtta agcc                                  1414
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