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EBI DbfetchID X82638; SV 1; linear; genomic DNA; STD; PRO; 9608 BP. XX AC X82638; XX DT 28-SEP-1995 (Rel. 45, Created) DT 22-APR-1996 (Rel. 47, Last updated, Version 9) XX DE C.sordelii cytotoxin gene XX KW cytotoxin. XX OS Clostridium sordellii OC Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; OC Clostridium. XX RN [1] RX DOI; 10.1016/0378-1119(95)00263-6 RX PUBMED; 7642137. RA Green G.A., Schue V., Monteil H.; RT "Cloning and characterization of the cytotoxin L-encoding gene of RT Clostridium sordellii: homology with Clostridium difficile cytotoxin B"; RL Gene 161(1):57-61(1995). XX RN [2] RP 1-9608 RA Green G.A.; RT ; RL Submitted (14-NOV-1994) to the EMBL/GenBank/DDBJ databases. RL G.A. Green, Inst. de Bacteriologie, 3, Rue Koeberle, 67000 Strasbourg, RL FRANCE XX RN [3] RP 1-9608 RX PUBMED; 8544213. RA Green G.A., Schue V., Girardot R., Monteil H.; RT "Characterisation of an enterotoxin-negative, cytotoxin-positive strain of RT Clostridium sordellii"; RL J. Med. Microbiol. 44(1):60-64(1996). XX FH Key Location/Qualifiers FH FT source 1..9608 FT /organism="Clostridium sordellii" FT /strain="6018" FT /mol_type="genomic DNA" FT /db_xref="taxon:1505" FT CDS 476..7570 FT /transl_table=11 FT /product="cytotoxin L" FT /db_xref="InterPro:IPR018337" FT /db_xref="PDB:2VKD" FT /db_xref="UniProtKB/TrEMBL:Q46342" FT /protein_id="CAA57959.1" FT /translation="MNLVNKAQLQKMVYVKFRIQEDEYVAILNALEEYHNMSESSVVEK FT YLKLKDINNLTDNYLNTYKKSGRNKALKKFKEYLTMEVLELKNNSLTPVEKNLHFIWIG FT GQINDTAINYINQWKDVNSDYTVKVFYDSNAFLINTLKKTIVESATNNTLESFRENLND FT PEFDYNKFYRKRMEIIYDKQKHFIDYYKSQIEENPEFIIDNIIKTYLSNEYSKDLEALN FT KYIEESLNKITANNGNDIRNLEKFADEDLVRLYNQELVERWNLAAASDILRISMLKEDG FT GVYLDVDILPGIQPDLFKSINKPDSITNTSWEMIKLEAIMKYKEYIPGYTSKNFDMLDE FT EVQRSFESALSSKSDKSEIFLPLDDIKVSPLEVKIAFANNSVINQALISLKDSYCSDLV FT INQIKNRYKILNDNLNPSINEGTDFNTTMKIFSDKLASISNEDNMMFMIKITNYLKVGF FT APDVRSTINLSGPGVYTGAYQDLLMFKDNSTNIHLLEPELRNFEFPKTKISQLTEQEIT FT SLWSFNQARAKSQFEEYKKGYFEGALGEDDNLDFAQNTVLDKDYVSKKILSSMKTRNKE FT YIHYIVQLQGDKISYEASCNLFSKDPYSSILYQKNIEGSETAYYYYVADAEIKEIDKYR FT IPYQISNKRNIKLTFIGHGKSEFNTDTFANLDVDSLSSEIETILNLAKADISPKYIEIN FT LLGCNMFSYSISAEETYPGKLLLKIKDRVSELMPSISQDSITVSANQYEVRINEEGKRE FT ILDHSGKWINKEESIIKDISSKEYISFNPKENKIIVKSKYLHELSTLLQEIRNNANSSD FT IDLEKKVMLTECEINVASNIDRQIVEGRIEEAKNLTSDSINYIKNEFKLIESISDSLYD FT LKHQNGLDDSHFISFEDISKTENGFRIRFINKETGNSIFIETEKEIFSEYATHISKEIS FT NIKDTIFDNVNGKLVKKVNLDAAHEVNTLNSAFFIQSLIEYNTTKESLSNLSVAMKVQV FT YAQLFSTGLNTITDASKVVELVSTALDETIDLLPTLSEGLPIIATIIDGVSLGAAIKEL FT SETNDPLLRQEIEAKIGIMAVNLTAASTAIVTSALGIASGFSILLVPLAGISAGIPSLV FT NNELILQDKATKVIDYFKHISLAETEGAFTLLDDKIIMPQDDLVLSEIDFNNNSITLGK FT CEIWRAEGGSGHTLTDDIDHFFSSPSITYRKPWLSIYDVLNIKKEKIDFSKDLMVLPNA FT PNRVFGYEMGWTPGFRSLDNDGTKLLDRIRDHYEGQFYWRYFAFIADALITKLKPRYED FT TNVRINLDGNTRSFIVPVITTEQIRKNLSYSFYGSGGSYSLSLSPYNMNIDLNLVENDT FT WVIDVDNVVKNITIESDEIQKGELIENILSKLNIEDNKIILNNHTINFYGDINESNRFI FT SLTFSILEDINIIIEIDLVSKSYKILLSGNCMKLIENSSDIQQKIDHIGFNGEHQKYIP FT YSYIDNETKYNGFIDYSKKEGLFTAEFSNESIIRNIYMPDSNNLFIYSSKDLKDIRIIN FT KGDVKLLIGNYFKDDMKVSLSFTIEDTNTIKLNGVYLDENGVAQILKFMNNAKSALNTS FT NSLMNFLESINIKNIFYNNLDPNIEFILDTNFIISGSNSIGQFELICDKDKNIQPYFIN FT FKIKETSYTLYVGNRQNLIVEPSYHLDDSGNISSTVINFSQKYLYGIDRYVNKVIIAPN FT LYTDEINITPVYKPNYICPEVIILDANYINEKINVNINDLSIRYVWDNDGSDLILIANS FT EEDNQPQVKIRFVNVFKSDTAADKLSFNFSDKQDVSVSKIISTFSLAAYSDGFFDYEFG FT LVSLDNDYFYINSFGNMVSGLIYINDSLYYFKPPKNNLITGFTTIDGNKYYFDPTKSGA FT ASIGEITIDGKDYYFNKQGILQVGVINTSDGLKYFAPAGTLDENLEGESVNFIGKLNID FT GKIYYFEDNYRAAVEWKLLDDETYYFNPKTGEALKGLHQIGDNKYYFDDNGIMQTGFIT FT INDKVFYFNNDGVMQVGYIEVNGKYFYFGKNGERQLGVFNTPDGFKFFGPKDDDLGTEE FT GELTLYNGILNFNGKIYFFDISNTAVVGWGTLDDGSTYYFDDNRAEACIGLTVINDCKY FT YFDDNGIRQLGFITINDNIFYFSESGKIELGYQNINGNYFYIDESGLVLIGVFDTPDGY FT KYFAPLNTVNDNIYGQAVKYSGLVRVNEDVYYFGETYKIETGWIENETDKYYFDPETKK FT AYKGINVVDDIKYYFDENGIMRTGLISFENNNYYFNEDGKMQFGYLNIKDKMFYFGKDG FT KMQIGVFNTPDGFKYFAHQNTLDENFEGESINYTGWLDLDGKRYYFTDEYIAATGSLTI FT DGYNYYFDPDTAELVVSE" FT CDS 7781..8206 FT /transl_table=11 FT /gene="ORF" FT /db_xref="InterPro:IPR006480" FT /db_xref="UniProtKB/TrEMBL:Q46343" FT /protein_id="CAA57960.1" FT /translation="MNITISFLSKNIFIKLVMLAITFDTLLGCLRAIKTHKFNSSFGIN FT GGIRKIAMIACIFFLSIVDMLTQFNFLFILPQEYINFFRFQHLGISEFFSMLFIFYESI FT SILKNMYLCGLPVPKNIQNKMYNLLYTITDEVKIEDR" XX SQ Sequence 9608 BP; 3862 A; 1064 C; 1373 G; 3309 T; 0 other; aaaaaagtaa aatatattga ttttataaat aaaaaataat aaaaaatata agaatataaa 60 atttttattc ttacagtctc tatttctaaa aataatttaa ttataaactt aatttcaaaa 120 caaatatcaa cagtaaccta tgcaattaaa cgtatataag ttggatttga taataacaaa 180 gctgaaagtg aaataataga taaaaaaata taaacttgca aatagtttta aataataaat 240 tcaaaaaaaa taaaagtatg tttacatatt catataaaaa taattcttac tttatgtaag 300 gtcagttaac ttaaccttat ttgaaataaa aatgttagga gggaataata tatgaaaact 360 taaattctaa aaaatttaat atcaatatac tttcataaat aagagaaaga atataaggta 420 ttttacaatt tagatataag tgctaaaaaa gatgttatat aaagggggaa ttttaatgaa 480 cttagttaac aaagcccaat tacaaaaaat ggtatatgta aaatttcgta ttcaagaaga 540 tgagtacgta gcaatattaa atgctctaga agaatatcac aacatgtcag aaagtagtgt 600 agttgaaaag tatttaaaat taaaggatat aaataatctc acagataatt acctgaacac 660 atataaaaaa tctggaagga ataaagcctt aaaaaaattt aaagaatatc taactatgga 720 agtattagag ctaaaaaata atagtctaac tccagtcgaa aaaaatttac attttatatg 780 gattggagga caaataaatg ataccgctat caactatata aatcaatgga aagatgtaaa 840 tagcgattat acagttaaag ttttttatga tagtaatgca tttttgataa atacattaaa 900 gaaaactatt gttgagtcag caacaaataa tactcttgag tcatttagag aaaacttaaa 960 tgaccctgaa ttcgattata ataaatttta tagaaaacgt atggaaataa tatatgataa 1020 acaaaaacat tttatagatt attataagtc tcagatagaa gagaatcctg aatttataat 1080 tgataatatt ataaaaacat atctctcaaa tgagtattca aaagacctag aagcccttaa 1140 taagtatatt gaagaatctt taaataaaat tactgctaat aatggtaatg atatcagaaa 1200 tctagaaaaa tttgctgatg aggatttggt aagattatat aatcaagaat tagtagaaag 1260 atggaatttg gctgctgctt ctgatatatt acgaatatct atgttaaaag aagatggtgg 1320 tgtatattta gatgttgaca tcttaccagg tatacaacca gatttattta aatctataaa 1380 caagcctgat tcgataacaa atacaagttg ggaaatgata aagttagagg ctataatgaa 1440 atataaggaa tatataccag ggtatacgtc aaagaatttt gacatgttag atgaagaagt 1500 tcaacgcagt tttgaatctg ctttaagttc taaatcagat aagtcagaaa tttttttgcc 1560 acttgatgat ataaaagtat ccccgttaga agtaaaaatt gcatttgcca ataactctgt 1620 tataaatcaa gccttaattt ctttaaaaga ttcctattgt agtgatttag taataaatca 1680 aattaaaaat agatataaaa tcttgaacga caacttaaat ccatccatta atgaaggtac 1740 tgactttaat actacaatga aaatttttag tgacaaatta gcatctattt ctaatgaaga 1800 taatatgatg tttatgataa aaattacaaa ttatttaaaa gttggatttg ctccagatgt 1860 tagaagtact attaacttaa gtggacctgg agtatataca ggagcttatc aagatttgtt 1920 aatgtttaaa gataatagta caaatattca tttactagaa cctgagttaa gaaattttga 1980 gtttcctaaa actaaaattt ctcaattaac agaacaggaa ataactagtt tatggtcatt 2040 taaccaagca agagccaagt ctcaatttga agaatataaa aaaggttatt ttgaaggtgc 2100 acttggagaa gatgataatc ttgattttgc tcaaaataca gtacttgata aagattatgt 2160 ttctaaaaaa atattatcat caatgaaaac ccgaaataaa gaatatattc attatattgt 2220 tcaactacaa ggagataaaa tcagctatga agcatcatgt aacttatttt caaaagatcc 2280 ttattctagt atactatatc agaaaaatat agaaggttca gaaacagcat attactatta 2340 tgttgcagat gctgagataa aagaaataga taaatataga attccatatc aaatttctaa 2400 taaacgtaat attaaattaa cttttattgg tcatggtaaa tctgaattta atactgatac 2460 atttgccaat cttgatgtag attcattatc ttctgagata gaaacaatat taaatttagc 2520 taaagcagat atttctccta agtatataga aataaattta ctgggatgta acatgttcag 2580 ctactctatc agcgcagaag agacttatcc tggaaaactt ttacttaaaa ttaaagatag 2640 agtatcagaa ttaatgccat ctataagtca agactctatt acagtaagtg caaatcaata 2700 tgaagttaga ataaatgaag aaggaaaaag agaaatatta gatcattctg gtaaatggat 2760 aaataaagaa gaaagtatta taaaggatat ttcatcaaaa gaatatatat catttaatcc 2820 aaaagaaaat aaaattatag tgaaatctaa atatttacat gagctgtcta cattattaca 2880 agaaattagg aataatgcca attcaagtga tattgatcta gaaaaaaaag taatgttaac 2940 agaatgtgag ataaatgttg cttcaaatat agatagacag attgtggaag gaagaattga 3000 agaagctaaa aatttgactt ctgactctat taattatata aaaaatgaat ttaaactaat 3060 agaatctatt tctgattcat tatatgattt aaaacatcaa aatggattag atgattctca 3120 ttttatatct tttgaggata tatccaagac tgaaaatgga tttaggataa ggttcattaa 3180 taaagaaact ggaaactcta tatttataga aactgaaaaa gaaattttct ctgaatatgc 3240 tactcatata tctaaagaaa tttctaatat aaaagatact atatttgata atgtaaatgg 3300 caaattagta aaaaaagtaa atctagatgc tgcacatgaa gtaaatactc taaattctgc 3360 cttttttata caatcattaa tcgaatataa tactactaaa gaatcactta gtaatttaag 3420 tgtagcaatg aaggttcaag tttatgctca attatttagt actggtttaa atactattac 3480 agatgcttct aaagttgttg agttagtatc aactgcatta gatgaaacta tagacttact 3540 tcctacatta tctgaaggat tacctataat tgctacaata atagatggtg taagcttagg 3600 cgcggcaatt aaagaactca gcgaaacaaa tgacccatta ttaagacaag aaatagaagc 3660 caagataggt ataatggctg taaatttaac agcagcttca actgcaatcg ttacttcagc 3720 tttaggaata gctagtggtt ttagcatact tttagttcct ttggcaggaa tttcagcagg 3780 gataccaagt ttagtaaaca atgaacttat actccaagat aaggcaacaa aagttataga 3840 ttattttaaa catatttcat tagctgagac tgagggagca tttacattat tagatgataa 3900 aataattatg cctcaagatg acttggtatt atcagaaata gactttaata ataattcaat 3960 aactttaggt aaatgtgaaa tctggagagc tgaaggtggt tcaggccata ccttaactga 4020 tgatatagat catttctttt catcaccatc aataacatat agaaaaccat ggttatctat 4080 atatgatgta ttaaatataa aaaaagaaaa aattgatttt tcaaaagatt taatggtatt 4140 acctaatgca cctaataggg tatttggtta tgaaatggga tggacaccag ggttcagaag 4200 tttagacaat gacggcacta aattattaga tcgtataaga gatcattatg aaggtcaatt 4260 ttattggaga tatttcgctt ttatagctga tgctttaata acaaaattaa aaccacgata 4320 tgaagatact aatgtaagaa taaatctaga tggcaatact agaagcttta tagttccagt 4380 tataaccaca gaacaaataa gaaaaaattt atcttattct ttttatggtt cagggggatc 4440 ttattcatta tctctttctc catataatat gaatatagat ttaaatctag ttgaaaatga 4500 tacttgggtt atagatgttg ataatgttgt aaaaaacatc actatagagt cagatgaaat 4560 acaaaaaggt gaattaatag aaaatatttt atctaagcta aatattgaag ataataaaat 4620 tattttaaat aatcatacta ttaatttcta tggagatata aatgaaagca acagatttat 4680 atctttaaca ttttcaattt tagaggatat aaatataatt atagaaattg atttagtatc 4740 aaaatcttat aaaatacttc tttctggtaa ttgtatgaaa ttgatagaaa actcatctga 4800 tattcaacaa aagatagatc atataggatt taatggtgaa catcagaaat atatacctta 4860 tagttatata gataatgaaa ctaaatacaa cggttttatt gactactcta aaaaagaagg 4920 tctgtttaca gctgaatttt ctaatgaatc cattataagg aatatttata tgcctgatag 4980 taataattta tttatatatt ctagtaaaga tttaaaagat attagaatta taaataaagg 5040 tgatgttaaa ttactaatag gaaattactt taaagatgat atgaaggtat cactttcttt 5100 cactatagaa gatacaaata ctataaagtt gaatggtgta tatctagatg aaaatggagt 5160 agcacaaata ttgaaattta tgaataatgc aaaaagtgct ttaaatactt caaactcgtt 5220 aatgaatttc ttagaaagta tcaatataaa aaatattttc tacaataatc tagaccctaa 5280 tatcgagttt atactagata ctaatttcat aataagtggt agcaattcta ttgggcaatt 5340 tgaacttatc tgtgataaag ataaaaatat acaaccatat tttattaact ttaaaataaa 5400 agaaactagc tataccttat atgtaggaaa tagacaaaat ttgatagtgg aaccaagtta 5460 tcacttagat gattctggaa atatatcttc aactgtcatt aatttctctc agaaatatct 5520 ttatggaata gaccgttatg ttaataaagt tataattgca ccaaatttat atacagatga 5580 aataaatata acacctgtat ataaaccaaa ttatatttgt ccagaagtta ttatattaga 5640 tgcaaattat ataaacgaaa aaataaatgt taatatcaat gacttatcta tacgatatgt 5700 atgggataat gatggtagtg atcttattct tatagcaaat agtgaggaag ataatcaacc 5760 acaagttaaa ataagatttg ttaatgtctt taaaagcgat actgcagcag ataagttgtc 5820 ttttaacttc agtgataagc aagatgtatc tgtaagtaaa attatttcaa cattttcact 5880 tgcagcttat agcgatggat tttttgacta tgaatttggt ctggtttctt tagataatga 5940 ttacttttat attaatagtt ttggaaatat ggtatctgga ttaatatata ttaatgattc 6000 attatattat ttcaaaccac caaaaaataa cttgataact ggattcacaa ctatagatgg 6060 taataaatat tactttgacc caacgaagag tggagctgca tcaataggag aaataacaat 6120 tgatggtaaa gattattact ttaacaaaca aggtattttg caagtaggag ttataaatac 6180 atctgatgga ttaaagtatt ttgctcctgc tggtacactt gatgaaaact tagagggaga 6240 atcagtaaat tttattggaa aattaaatat tgatggaaaa atttattatt ttgaagataa 6300 ttatagagcc gctgtagagt ggaaattatt agatgatgaa acatactatt tcaatccaaa 6360 aacaggagaa gcccttaaag gtttacatca aattggtgat aataaatatt attttgatga 6420 taatggaatt atgcaaactg gtttcattac tataaatgat aaggtatttt attttaataa 6480 tgatggtgtg atgcaagttg gatatattga ggtaaatggt aaatattttt attttggcaa 6540 aaatggagaa agacaattag gagtatttaa tactccagat ggatttaaat tttttggtcc 6600 taaagatgat gatttaggaa ctgaagaagg ggaactaacc ttatataatg gtatattgaa 6660 ttttaatggg aaaatctatt tttttgatat ctcaaataca gctgtagtcg gatggggtac 6720 tcttgatgat ggctctacat attatttcga tgataataga gcagaagcat gcataggttt 6780 aacagtaatt aatgattgta agtattattt tgatgataac ggaataaggc aattaggatt 6840 tatcactata aatgacaata tattttattt ctctgaatct ggaaaaatag agttaggata 6900 ccaaaatata aatggtaact atttctacat agatgaaagt ggtttagttc taattggagt 6960 atttgatacc ccagacggat ataaatattt tgcacctctt aatactgtaa atgataatat 7020 ttatggacaa gcagttaaat atagtggttt agtaagggtt aatgaggacg tatattattt 7080 tggtgaaaca tataaaattg aaactggatg gatagaaaat gaaactgata aatattattt 7140 tgatccagag actaaaaaag catataaagg cattaatgta gttgatgata taaaatatta 7200 tttcgatgag aatggtataa tgagaacagg gcttatatca tttgaaaata ataattatta 7260 cttcaatgaa gatggtaaaa tgcaatttgg ttatctaaat ataaaagata aaatgtttta 7320 ttttggtaaa gatggtaaaa tgcagattgg agtatttaat accccagatg gatttaaata 7380 ctttgcacat caaaatactt tagatgagaa ttttgagggg gaatcaataa actatactgg 7440 ttggttagat ttagatggta aaagatatta ttttacagat gaatatatag cagcaactgg 7500 ctcattgact attgatggtt acaattacta ttttgaccct gatacagctg aattagtagt 7560 tagtgaataa atttaataaa atcaaaatat tgttgatcct ataacaatcg taagagtgat 7620 tattatgtag aattagaaca atatataaaa gtattttcta aaataaaaat ttatcctaaa 7680 ggatgtgagc tactattaat atatagtagt ttacatcctt atatctatat gaattctata 7740 ataatataat attattttaa ttacaaaact aggaggcatt atgaatataa caatatcttt 7800 tttatcaaaa aatatattta taaaactagt gatgctagct ataacatttg atacattatt 7860 gggatgtttg agggcaataa aaacccataa atttaattct agttttggaa tcaatggagg 7920 aattagaaaa atagcaatga tagcttgtat attttttcta tcaatagttg atatgctaac 7980 acaattcaat tttttattta tattgccaca agaatatatt aattttttta gatttcaaca 8040 tctaggaata tcagaatttt tttctatgct atttattttt tatgaaagta taagtatatt 8100 aaaaaatatg tatctatgtg gtttaccagt acctaaaaat atacaaaaca aaatgtataa 8160 tttgttatat acaataacag acgaagtaaa aattgaggat agataaaaat aatgaaaata 8220 tgtattaccg taaattataa tcttttaaag aattgcatat atactagaga ctatattaaa 8280 aaatagaggc ttatatatgc taaacttttc aaatttaaaa tccctatcat acattgattt 8340 caaaaccaat aaaacctatt tacatagtaa gtaaatccac tatagtaggt gataatttat 8400 tctataaatc tatttaggat tactatcaaa aaatacattt atagaatata ttttataaat 8460 tatattctat aaatgtattt taaattgtag gaaaaacttt agaacctaaa atacataatc 8520 tacctctaag aaacttacat caacttgact tattcggtat ctttctagta tctacaccta 8580 cccctaatat ttattttatt actaaaatca agtctatttg gaagattaag aaaaattctt 8640 taaaccctta ctctctcatt taattttttt agtactccta caatattatt ttatatttaa 8700 gtatatatac ttttaatata gaaacgtacg caccctttgg tggcatttat tactattgaa 8760 gccttctgat ctattattaa atatatatct ataatatgta caacaaaagt ttaaccttta 8820 ccacttcgat ttatactata attaagttat tttagtagta aaaaataaaa atgatttctg 8880 tatattacag aaatcatttt tgtcaaacat atatttttaa ccatctatac caaagaaata 8940 tatagcccca tcgatagtaa aatatcctcc atctgcatct atagcagtat caggcataaa 9000 gtaataggta atacattaat ggtatcgttt attgcattga tattagattt actaattgaa 9060 tagaatcgta tatagtattt aaaccagtac taaatagttg agcataaagt tggaccttaa 9120 cctaagtgct taaattattt aatacatatt tgttgctact ataatctatt catgattgaa 9180 taaagaatgc tgaatttaat gtattaatat gaggtacata ttctaactct atattccctt 9240 ttaaattgtc attgaaatct ataattataa gatgttggtt taaaaattga tatctatttt 9300 ttacttgttc tattactaag ttagtaagat atgaaccttt ttttgatatc aaggcttgat 9360 ttataacact tcctaaagcg aaagctattt ttatttcaag atcaaataca tctaaaattt 9420 cctaacttag aaaatatctc agatttttca cttttacttt ctaacgtaat ttgaaagtaa 9480 tcttttaatt gttgatccaa ttgaacaaag ttttttgatg tataattata tatatatttc 9540 ttatacttca taatagccta taattttatt atttcccaac tatctactcc gatagagcta 9600 ggtctaga 9608 // |
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