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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   X74422; SV 1; linear; genomic DNA; STD; FUN; 1526 BP.
XX
AC   X74422;
XX
DT   06-AUG-1993 (Rel. 36, Created)
DT   18-APR-2005 (Rel. 83, Last updated, Version 5)
XX
DE   S.pombe tms1 gene for putative dehydrogenase (multicopy suppressor of p53
DE   tumour mutant induced growth arrest)
XX
KW   dehydrogenase; multicopy suppressor; tms1 gene.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
XX
RN   [1]
RP   1-1526
RA   Wagner P.;
RT   ;
RL   Submitted (30-JUL-1993) to the EMBL/GenBank/DDBJ databases.
RL   P. Wagner, Universtitaet des Saarlandes, Medizinische Biochemie, Gebaude
RL   44, 66421 Homburg/Saar, FRG
XX
RN   [2]
RP   1-1526
RX   DOI; 10.1111/j.1432-1033.1993.tb18299.x
RX   PUBMED; 8223615.
RA   Wagner P., Grimaldi M., Jenkins J.R.;
RT   "Putative dehydrogenase tms1 suppresses growth arrest induced by a p53
RT   tumour mutant in fission yeast";
RL   Eur. J. Biochem. 217(2):731-736(1993).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1526
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="G72h-"
FT                   /mol_type="genomic DNA"
FT                   /haplotype="haploid"
FT                   /clone_lib="pWH5-HindIII partial digest of genomic DNA"
FT                   /clone="ptms1-1"
FT                   /clone="ptms1-2"
FT                   /db_xref="taxon:4896"
FT   TATA_signal     10..15
FT   prim_transcript 67..>1526
FT   CDS             316..1359
FT                   /gene="tms1"
FT                   /product="dehydrogenase"
FT                   /function="multicopy suppressor of p53 tumour mutant
FT                   induced growth arrest"
FT                   /db_xref="GENEDB:SPBC1773.05c"
FT                   /db_xref="GOA:P36624"
FT                   /db_xref="HSSP:1E3J"
FT                   /db_xref="InterPro:IPR002328"
FT                   /db_xref="UniProtKB/Swiss-Prot:P36624"
FT                   /protein_id="CAA52443.1"
FT                   /translation="MDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWKEGGIGDFI
FT                   LKKPMILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFA
FT                   ATPPYDGTLRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTRGNLKCGSRVLVM
FT                   GCGTVGLLMMAVAKAYGAIDIVAVDASPSRVEFAQKYVGAKPFTPIAAKENESLPDYAQ
FT                   RYKQAIIEKYGEFDFAVDATGVGICIHTAVLALKRGGTFVQAGNGKPVIDFPINHIINY
FT                   EINVLGSFRYAHGCYKQSLFLVSNGLVDVKPLITHRFAFKDALKAYETVASGEEGVLKV
FT                   IIGGPDA"
FT   polyA_signal    1469..1474
XX
SQ   Sequence 1526 BP; 423 A; 308 C; 330 G; 465 T; 0 other;
     tagggtaact ataaattgag ggcagttcgc aacagctgtt caatagattc agaaattttt        60
     agtagacatc gcatctcatt caatacttaa cttctgttcc tgtcaactat atagtactat       120
     tgtaatcggt acagtcagaa cagaataata tcatctactt gaaagaaaca ataattaatt       180
     aattgttttt ggaatccctt tcagttctta aagcaaatca tctaaatcgt ttattcatac       240
     ccttgttata ttgaaatttt caattaaagc tacaaaatcg gacctcgaga gaaagcattc       300
     gtcttgcgca agaaaatgga cactgcgatc gaggatcgtc ctggtcagac tttgactgat       360
     gaccatcaag tcaaagtcgc catcaaggct actggaattt gcggtagcga cgttcattac       420
     tggaaagaag gcggcattgg agacttcatt ctgaagaaac ccatgatctt gggccatgaa       480
     agcgcaggtg ttgtcgtcga agttggaaag ggtgtctctt ccttaaagcc cggtgatcca       540
     gttgcggttg aacccggttg cgtttgtcgt ttatgcgatt actgtcgttc tggtagatac       600
     aacttgtgtc ctcatatgga gtttgctgct actcctccat acgacggaac tcttcgcact       660
     tactacatta ccacagaaga cttttgcacc aagctaccta agcagatttc agttgaagag       720
     ggtgctcttt tcgagcccat gagtgttgcc gttcacgcta tgacccgcgg taacctcaag       780
     tgtggttcgc gagtccttgt gatgggatgt ggtacagttg gcctcttgat gatggctgtt       840
     gctaaggctt atggggcaat tgacattgtt gctgttgacg cttccccctc tcgtgtagag       900
     tttgctcaaa agtatgttgg tgcaaagccc tttactccca ttgctgccaa ggagaatgag       960
     tcattacccg actacgcgca gagatataag caagcaatca tcgaaaagta cggtgagttt      1020
     gattttgctg tagatgccac tggcgttggc atctgcattc acactgccgt attggcactc      1080
     aaacgaggtg gtacatttgt gcaagctgga aatggaaaac ctgtgattga ttttcccatt      1140
     aaccacatca ttaattatga aatcaacgtc ttaggtagtt tccgttacgc ccatggatgc      1200
     tacaaacaat ctctatttct ggtatcaaac gggctggttg acgttaaacc actcattacc      1260
     cacagattcg ctttcaaaga tgccctaaag gcttacgaaa ctgtcgcaag cggcgaagaa      1320
     ggtgtgctga aagtaatcat tggtggtccc gatgcgtagt tctttgagta tttcgatttg      1380
     attatttttc attataagag ccaagctttc agagagtact ctcatgagaa attattttat      1440
     gtgttagcca tgttatatcc ctaatttcaa taaatgttgt ttagaaagaa aaaatcttat      1500
     tatatacatg taaaaacaaa tgtgta                                           1526
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